amphetamine has been researched along with Genetic Predisposition in 13 studies
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Similarly, subjective responses to amphetamine did not differ by a family history of alcoholism." | 3.73 | Striatal dopamine release and family history of alcoholism. ( Alexander, M; Brasic, J; Kumar, A; Kuwabara, H; McCaul, ME; Munro, CA; Oswald, LM; Wand, GS; Wong, DF; Ye, W; Zhou, Y, 2006) |
| "Other PTSD symptoms, such as anxiety (elevated plus maze) and hyperarousal (acoustic startle response), were also investigated in these rats." | 1.40 | Only susceptible rats exposed to a model of PTSD exhibit reactivity to trauma-related cues and other symptoms: an effect abolished by a single amphetamine injection. ( Gisquet-Verrier, P; Toledano, D, 2014) |
| "The etiology of drug addiction, a central nervous system (CNS) disease, is not fully known." | 1.39 | Estimation of BDNF gene polymorphism and predisposition to dependence development for selected psychoactive compounds: genetic aspects of addiction with the selected drugs, amphetamine, tetrahydrocannabinol and opiates. ( Biskupska, J; Borowiak, KS; Ciechanowicz, A; Janus, T; Karlin-Grazewicz, K; Machoy-Mokrzynska, A; Ossowski, A; Potocka-Banas, B; Waloszczyk, P, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (53.85) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, SJ | 1 |
| Liao, DL | 1 |
| Chen, CH | 1 |
| Wang, TY | 1 |
| Chen, KC | 1 |
| Toledano, D | 1 |
| Gisquet-Verrier, P | 1 |
| Zhang, K | 1 |
| Zhao, Y | 1 |
| Wang, Q | 1 |
| Jiang, H | 1 |
| Du, J | 1 |
| Yu, S | 1 |
| Zhao, M | 1 |
| Won, H | 1 |
| Mah, W | 1 |
| Kim, E | 2 |
| Kim, JW | 1 |
| Hahm, EK | 1 |
| Kim, MH | 1 |
| Cho, S | 1 |
| Kim, J | 1 |
| Jang, H | 1 |
| Cho, SC | 1 |
| Kim, BN | 1 |
| Shin, MS | 1 |
| Seo, J | 1 |
| Jeong, J | 1 |
| Choi, SY | 1 |
| Kim, D | 1 |
| Kang, C | 1 |
| Carvalho, M | 1 |
| Carmo, H | 1 |
| Costa, VM | 1 |
| Capela, JP | 1 |
| Pontes, H | 1 |
| Remião, F | 1 |
| Carvalho, F | 1 |
| Bastos, Mde L | 1 |
| Biskupska, J | 1 |
| Borowiak, KS | 1 |
| Karlin-Grazewicz, K | 1 |
| Janus, T | 1 |
| Waloszczyk, P | 1 |
| Potocka-Banas, B | 1 |
| Machoy-Mokrzynska, A | 1 |
| Ossowski, A | 1 |
| Ciechanowicz, A | 1 |
| Alcaro, A | 1 |
| Cabib, S | 1 |
| Ventura, R | 2 |
| Puglisi-Allegra, S | 2 |
| Sorokin, AIa | 1 |
| Kudrin, VS | 1 |
| Klodt, PM | 1 |
| Tuomisto, L | 1 |
| Poletaeva, II | 1 |
| Raevskiĭ, KS | 1 |
| Munro, CA | 1 |
| McCaul, ME | 1 |
| Oswald, LM | 1 |
| Wong, DF | 1 |
| Zhou, Y | 1 |
| Brasic, J | 1 |
| Kuwabara, H | 1 |
| Kumar, A | 1 |
| Alexander, M | 1 |
| Ye, W | 1 |
| Wand, GS | 1 |
| Hunsley, MS | 1 |
| Curtis, WR | 1 |
| Palmiter, RD | 1 |
| Fleming, SM | 1 |
| Salcedo, J | 1 |
| Hutson, CB | 1 |
| Rockenstein, E | 1 |
| Masliah, E | 1 |
| Levine, MS | 1 |
| Chesselet, MF | 1 |
| Richfield, EK | 1 |
| Thiruchelvam, MJ | 1 |
| Cory-Slechta, DA | 1 |
| Wuertzer, C | 1 |
| Gainetdinov, RR | 1 |
| Caron, MG | 1 |
| Di Monte, DA | 1 |
| Federoff, HJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Candidate Gene Screening for 6-14 Year Old Patients With ADHD (Attention Deficit/ Hyperactivity Disorder)[NCT03018574] | 100 participants (Actual) | Observational | 2016-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for amphetamine and Genetic Predisposition
| Article | Year |
|---|---|
Toxicity of amphetamines: an update.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Chemical and | 2012 |
12 other studies available for amphetamine and Genetic Predisposition
| Article | Year |
|---|---|
Construction and Analysis of Protein-Protein Interaction Network of Heroin Use Disorder.
Topics: Alcoholism; Amphetamine; Cocaine-Related Disorders; Genetic Predisposition to Disease; Heroin Depend | 2019 |
Only susceptible rats exposed to a model of PTSD exhibit reactivity to trauma-related cues and other symptoms: an effect abolished by a single amphetamine injection.
Topics: Amphetamine; Animals; Anxiety; Cues; Disease Models, Animal; Genetic Predisposition to Disease; Indi | 2014 |
Association study of GABA system genes polymorphisms with amphetamine-induced psychotic disorder in a Han Chinese population.
Topics: Adult; Amphetamine; Asian People; Case-Control Studies; Female; gamma-Aminobutyric Acid; Gene Freque | 2016 |
GIT1 is associated with ADHD in humans and ADHD-like behaviors in mice.
Topics: Adaptor Proteins, Signal Transducing; Amphetamine; Animals; Attention Deficit Disorder with Hyperact | 2011 |
Estimation of BDNF gene polymorphism and predisposition to dependence development for selected psychoactive compounds: genetic aspects of addiction with the selected drugs, amphetamine, tetrahydrocannabinol and opiates.
Topics: Adolescent; Adult; Amphetamine; Brain-Derived Neurotrophic Factor; Dronabinol; Female; Genetic Predi | 2013 |
Genotype- and experience-dependent susceptibility to depressive-like responses in the forced-swimming test.
Topics: Adrenergic Uptake Inhibitors; Amphetamine; Analysis of Variance; Animals; Antidepressive Agents, Tri | 2002 |
[The interstrain differences in the effects of D-amphetamine and raclopride on dorsal striatum dopaminergic system in KM and Wistar rats (microdialysis study)].
Topics: Amphetamine; Animals; Corpus Striatum; Dopamine; Epilepsy, Reflex; Genetic Predisposition to Disease | 2004 |
Environment makes amphetamine-induced dopamine release in the nucleus accumbens totally impulse-dependent.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Disease Models, Animal; Dopamine; Dopamine Upta | 2005 |
Striatal dopamine release and family history of alcoholism.
Topics: Adolescent; Adult; Alcoholism; Amphetamine; Basal Ganglia; Dopamine; Female; Genetic Predisposition | 2006 |
Behavioral and sleep/wake characteristics of mice lacking norepinephrine and hypocretin.
Topics: Amphetamine; Animals; Behavior, Animal; Brain; Dopamine Agonists; Electroencephalography; Electromyo | 2006 |
Behavioral effects of dopaminergic agonists in transgenic mice overexpressing human wildtype alpha-synuclein.
Topics: alpha-Synuclein; Amphetamine; Animals; Apomorphine; Behavior, Animal; Benserazide; Brain; Disease Mo | 2006 |
Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aging; alpha-Synuclein; Amphetamine; Animals; Behavior | 2002 |