amphetamine has been researched along with Dystonia in 8 studies
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)
Excerpt | Relevance | Reference |
---|---|---|
"Excepting clozapine and DOD 647, all drugs induced dystonia." | 3.70 | New and old antipsychotics versus clozapine in a monkey model: adverse effects and antiamphetamine effects. ( Gerlach, J; Peacock, L, 1999) |
"Early onset torsion dystonia (DYT1), the most common form of hereditary primary dystonia, is caused by a mutation in the TOR1A gene, which codes for the protein, torsinA." | 1.36 | Function of dopamine transporter is compromised in DYT1 transgenic animal model in vivo. ( Balcioglu, A; Hewett, J; Johanson, P; Sharma, N; Standaert, D, 2010) |
"Neither (-)-3-PPP nor SND 919 produced dystonia, but had observable dopamine D2 receptor agonistic effects, (-)-3-PPP producing emesis at 1-4 mg/kg and SND 919 producing motoric unrest and stereotypy at 0." | 1.29 | Effects of several partial dopamine D2 receptor agonists in Cebus apella monkeys previously treated with haloperidol. ( Gerlach, J; Peacock, L, 1993) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (12.50) | 18.7374 |
1990's | 4 (50.00) | 18.2507 |
2000's | 2 (25.00) | 29.6817 |
2010's | 1 (12.50) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Shen, YC | 1 |
Hewett, J | 1 |
Johanson, P | 1 |
Sharma, N | 1 |
Standaert, D | 1 |
Balcioglu, A | 1 |
Capstick, C | 1 |
Checkley, S | 1 |
Gray, J | 1 |
Dawe, S | 1 |
Peacock, L | 3 |
Gerlach, J | 3 |
Hansen, L | 1 |
Mørkeberg, F | 1 |
Rehders, JH | 1 |
Löscher, W | 1 |
Richter, A | 1 |
McKeon, TW | 1 |
Lorden, JF | 1 |
Beales, M | 1 |
Oltmans, GA | 1 |
8 other studies available for amphetamine and Dystonia
Article | Year |
---|---|
Amphetamine as a risk factor for aripiprazole-induced acute dystonia.
Topics: Acute Disease; Adult; Amphetamine; Aripiprazole; Dystonia; Humans; Male; Piperazines; Quinolones; Ri | 2008 |
Function of dopamine transporter is compromised in DYT1 transgenic animal model in vivo.
Topics: Amphetamine; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; D | 2010 |
Dystonia induced by amphetamine and haloperidol.
Topics: Adult; Amphetamine; Dose-Response Relationship, Drug; Drug Synergism; Dystonia; Female; Haloperidol; | 1994 |
Effects of several partial dopamine D2 receptor agonists in Cebus apella monkeys previously treated with haloperidol.
Topics: Administration, Oral; Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Benzothiazoles; | 1993 |
Chronic dopamine D1, dopamine D2 and combined dopamine D1 and D2 antagonist treatment in Cebus apella monkeys: antiamphetamine effects and extrapyramidal side effects.
Topics: Amphetamine; Animals; Arousal; Basal Ganglia Diseases; Benzazepines; Benzofurans; Cebus; Dopamine Ag | 1999 |
New and old antipsychotics versus clozapine in a monkey model: adverse effects and antiamphetamine effects.
Topics: Amphetamine; Animals; Antipsychotic Agents; Cebus; Clozapine; Dextroamphetamine; Disease Models, Ani | 1999 |
Evidence for striatal dopaminergic overactivity in paroxysmal dystonia indicated by microinjections in a genetic rodent model.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Amphetamine; Animals; Benzazepine | 2000 |
Alterations in the noradrenergic projection to the cerebellum of the dystonic (dt) rat.
Topics: alpha-Methyltyrosine; Amphetamine; Animals; Cerebellum; Dystonia; Female; Male; Methoxyhydroxyphenyl | 1986 |