amphetamine has been researched along with Drug Overdose in 41 studies
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this report, a pediatric case of bowel obstruction with sepsis complicated by methamphetamine toxicity is described." | 7.91 | A complicated case of bowel obstruction with sepsis and methamphetamine toxicity in a child with pica. ( Jones, P; Shattuck, B; Stevens, C; Ton, E, 2019) |
| "A fatal case of massive intracerebral hemorrhage in a 20-year-old woman after first-time amphetamine abuse is described along with a review of the literature." | 7.70 | [Fatal intracerebral hemorrhage after amphetamine intake]. ( Brorholt-Petersen, JU; Christensen, HR, 2000) |
| "In this report, a pediatric case of bowel obstruction with sepsis complicated by methamphetamine toxicity is described." | 3.91 | A complicated case of bowel obstruction with sepsis and methamphetamine toxicity in a child with pica. ( Jones, P; Shattuck, B; Stevens, C; Ton, E, 2019) |
| "A fatal case of massive intracerebral hemorrhage in a 20-year-old woman after first-time amphetamine abuse is described along with a review of the literature." | 3.70 | [Fatal intracerebral hemorrhage after amphetamine intake]. ( Brorholt-Petersen, JU; Christensen, HR, 2000) |
| "Naloxone immediately reversed respiratory depression induced by fentanyl only at the highest dose tested (10 mg/kg)." | 1.91 | Amphetamines modulate fentanyl-depressed respiration in a bidirectional manner. ( Beardsley, PM; Elder, HJ; Varshneya, NB; Walentiny, DM, 2023) |
| "As amphetamines were present in the urine sample, it was assumed that the tranylcypromine had been converted to amphetamines metabolically." | 1.46 | Discrimination Between Drug Abuse and Medical Therapy: Case report of a tranylcypromine overdose-related fatality. ( Akhgari, M; Etemadi-Aleagha, A; Ghasemi, A; Jokar, F, 2017) |
| "Tramadol was quantified to be 140 mg/L, approximately 470 times the therapeutic range." | 1.39 | Complicated suicide versus autoeroticism?: a case involving multiple drugs and a porta-potty. ( Dickerson, EM; Jones, P; Prahlow, JA; Regnier, J; Wilkins, D, 2013) |
| " Pathohistology revealed microvascular steatosis in the liver, which raised the possibility of chronic use of toxic substances." | 1.38 | [A new designer drug: methylone related death]. ( Kereszty, EM; Kovács, K; Tóth, AR, 2012) |
| "Mebeverine-alcohol is a precursor for a number of amphetamine-like compounds." | 1.33 | Investigative implications of the instability and metabolism of mebeverine. ( Burgess, V; Elliott, S, 2006) |
| "Fenfluramine was detected in the blood sample collected from the victim at the concentration of 7." | 1.31 | Simple and simultaneous analysis of fenfluramine, amphetamine and methamphetamine in whole blood by gas chromatography-mass spectrometry after headspace-solid phase microextraction and derivatization. ( Hara, K; Imamura, T; Kojima, T; Liu, J; Namera, A; Okajima, K; Yashiki, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.88) | 18.7374 |
| 1990's | 8 (19.51) | 18.2507 |
| 2000's | 14 (34.15) | 29.6817 |
| 2010's | 9 (21.95) | 24.3611 |
| 2020's | 8 (19.51) | 2.80 |
| Authors | Studies |
|---|---|
| Elder, HJ | 1 |
| Varshneya, NB | 1 |
| Walentiny, DM | 1 |
| Beardsley, PM | 1 |
| Chang, HH | 1 |
| Zhang, H | 1 |
| Latimore, AD | 1 |
| Murray, BP | 1 |
| D'Souza, RR | 1 |
| Scovronick, N | 1 |
| Gribble, MO | 1 |
| Ebelt, ST | 1 |
| Stevens, C | 1 |
| Ton, E | 1 |
| Jones, P | 2 |
| Shattuck, B | 1 |
| Castro, AL | 1 |
| Tarelho, S | 1 |
| Almeida, D | 1 |
| Sousa, L | 1 |
| Franco, JM | 1 |
| Teixeira, HM | 1 |
| Chawarski, MC | 1 |
| Hawk, K | 2 |
| Edelman, EJ | 2 |
| O'Connor, P | 1 |
| Owens, P | 2 |
| Martel, S | 2 |
| Coupet, E | 2 |
| Whiteside, L | 1 |
| Tsui, JI | 1 |
| Rothman, R | 1 |
| Cowan, E | 2 |
| Richardson, L | 2 |
| Lyons, MS | 2 |
| Fiellin, DA | 2 |
| D'Onofrio, G | 2 |
| Vivolo-Kantor, AM | 1 |
| Hoots, BE | 1 |
| Seth, P | 1 |
| Jones, CM | 1 |
| Vohra, V | 1 |
| King, A | 1 |
| Daviskiba, S | 1 |
| Reed, B | 1 |
| Rockhill, S | 1 |
| Kern, P | 1 |
| Dean, D | 1 |
| Chawarski, M | 1 |
| O'Connor, PG | 1 |
| Huntley, K | 1 |
| Whiteside, LK | 1 |
| Rothman, RE | 1 |
| Pantalon, M | 1 |
| Black, JC | 1 |
| Bau, GE | 1 |
| Iwanicki, JL | 1 |
| Dart, RC | 1 |
| Weber, M | 1 |
| Lessig, R | 1 |
| Richter, C | 1 |
| Ritter, AP | 1 |
| Weiß, I | 1 |
| Akhgari, M | 1 |
| Jokar, F | 1 |
| Etemadi-Aleagha, A | 1 |
| Ghasemi, A | 1 |
| Connors, NJ | 1 |
| Alsakha, A | 1 |
| Larocque, A | 1 |
| Hoffman, RS | 1 |
| Landry, T | 1 |
| Gosselin, S | 1 |
| Tominaga, M | 1 |
| Michiue, T | 1 |
| Inamori-Kawamoto, O | 1 |
| Hishmat, AM | 1 |
| Oritani, S | 1 |
| Takama, M | 1 |
| Ishikawa, T | 1 |
| Maeda, H | 1 |
| Fulde, GW | 1 |
| Forster, SL | 1 |
| Kovaleva, J | 1 |
| Devuyst, E | 1 |
| De Paepe, P | 1 |
| Verstraete, A | 1 |
| Fujita, Y | 1 |
| Takahashi, K | 1 |
| Takei, M | 1 |
| Niitsu, H | 1 |
| Aoki, Y | 1 |
| Onodera, M | 1 |
| Fujino, Y | 1 |
| Inoue, Y | 1 |
| Endo, S | 1 |
| Talu, A | 1 |
| Rajaleid, K | 1 |
| Abel-Ollo, K | 1 |
| Rüütel, K | 1 |
| Rahu, M | 1 |
| Rhodes, T | 1 |
| Platt, L | 1 |
| Bobrova, N | 1 |
| Uusküla, A | 1 |
| Kovács, K | 1 |
| Tóth, AR | 1 |
| Kereszty, EM | 1 |
| Dickerson, EM | 1 |
| Wilkins, D | 1 |
| Regnier, J | 1 |
| Prahlow, JA | 1 |
| Jacobs, W | 1 |
| Zimmerman, JL | 1 |
| MITCHELL, HS | 1 |
| DENTON, RL | 1 |
| Kohrs, FP | 1 |
| Mann, C | 1 |
| Greenberg, R | 1 |
| Degenhardt, L | 1 |
| Roxburgh, A | 1 |
| Barker, B | 1 |
| Elliott, S | 1 |
| Burgess, V | 1 |
| Shah, HV | 1 |
| Irvine, GH | 1 |
| Bradley, M | 1 |
| Zaidi, SM | 1 |
| Al-Sharary, MM | 1 |
| Al-Khuwaitir, TS | 1 |
| Sajid, NU | 1 |
| FRANKEL, E | 1 |
| Pach, J | 1 |
| Pach, K | 1 |
| Targosz, D | 1 |
| Winnik, L | 1 |
| Obara, M | 1 |
| Cadier, MA | 1 |
| Clarke, JA | 1 |
| Galloway, G | 1 |
| Shulgin, AT | 1 |
| Kornfeld, H | 1 |
| Frederick, SL | 1 |
| Nolla-Salas, J | 1 |
| Félez, MA | 1 |
| Iglesias, MI | 1 |
| Brunet, M | 1 |
| Kronstrand, R | 1 |
| Druid, H | 1 |
| Holmgren, P | 1 |
| Rajs, J | 1 |
| Christophersen, AS | 1 |
| Smith-Kielland, A | 1 |
| Christensen, HR | 3 |
| Hedetoft, C | 1 |
| Namera, A | 1 |
| Yashiki, M | 1 |
| Liu, J | 1 |
| Okajima, K | 1 |
| Hara, K | 1 |
| Imamura, T | 1 |
| Kojima, T | 1 |
| Brorholt-Petersen, JU | 1 |
| Roberge, RJ | 1 |
| Luellen, JR | 1 |
| Reed, S | 1 |
| Kraner, JC | 1 |
| McCoy, DJ | 1 |
| Evans, MA | 1 |
| Evans, LE | 1 |
| Sweeney, BJ | 1 |
| Martin, TL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Opioid Use Disorder in the Emergency Department: Clinical Trials Network-0069[NCT03023930] | 1,731 participants (Actual) | Interventional | 2017-04-03 | Completed | |||
| HAART Adherence Among HIV-infected Persons and the Factors Affecting Treatment Adherence[NCT01369056] | 150 participants (Actual) | Interventional | 2010-07-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The primary effectiveness outcome is defined as the rates of patient engagement in formal addiction treatment on the 30th day post enrollment. (NCT03023930)
Timeframe: 30 Days Post Enrollment
| Intervention | Participants (Count of Participants) |
|---|---|
| Baseline Evaluation Period Cohort | 40 |
| IF Evaluation Period Cohort | 59 |
The primary implementation outcome will be evaluated assessing the rate of ED-initiated BUP therapy with referral for ongoing MAT (NCT03023930)
Timeframe: 12 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Baseline Evaluation Period Cohort | 2 |
| IF Evaluation Period Cohort | 53 |
4 reviews available for amphetamine and Drug Overdose
| Article | Year |
|---|---|
Antipsychotics for the treatment of sympathomimetic toxicity: A systematic review.
Topics: Amphetamine; Animals; Antipsychotic Agents; Cocaine; Drug Overdose; Humans; Illicit Drugs; Sympathom | 2019 |
The impact of amphetamine-type stimulants on emergency services.
Topics: Acute Disease; Aggression; Amphetamine; Amphetamine-Related Disorders; Anxiety; Central Nervous Syst | 2015 |
Poisonings and overdoses in the intensive care unit: general and specific management issues.
Topics: Adrenergic beta-Antagonists; Alcohols; Amphetamine; Analgesics; Antidotes; Calcium Channel Blockers; | 2003 |
[Amphetamine, ecstasy and cocaine. Clinical aspects of acute poisoning].
Topics: Amphetamine; Amphetamine-Related Disorders; Central Nervous System Stimulants; Cocaine; Cocaine-Rela | 1999 |
37 other studies available for amphetamine and Drug Overdose
| Article | Year |
|---|---|
Amphetamines modulate fentanyl-depressed respiration in a bidirectional manner.
Topics: Amphetamine; Analgesics, Opioid; Animals; Central Nervous System Stimulants; Drug Overdose; Fentanyl | 2023 |
Associations between short-term ambient temperature exposure and emergency department visits for amphetamine, cocaine, and opioid use in California from 2005 to 2019.
Topics: Amphetamine; Analgesics, Opioid; California; Cocaine; Cross-Over Studies; Drug Overdose; Emergency S | 2023 |
A complicated case of bowel obstruction with sepsis and methamphetamine toxicity in a child with pica.
Topics: Amphetamine; Central Nervous System Stimulants; Child; Colon, Sigmoid; Drug Overdose; Female; Foreig | 2019 |
MDMA Intoxication in a Potential Organ Donor with Cardiac Arrest.
Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Amphetamine; Drug Overdose; Forensic Medicine; Gas Chroma | 2020 |
Use of Amphetamine-Type Stimulants Among Emergency Department Patients With Untreated Opioid Use Disorder.
Topics: Adult; Amphetamine; Amphetamine-Related Disorders; Case-Control Studies; Central Nervous System Stim | 2020 |
Recent trends and associated factors of amphetamine-type stimulant overdoses in emergency departments.
Topics: Adult; Amphetamine; Central Nervous System Stimulants; Drug Overdose; Emergency Service, Hospital; F | 2020 |
Stimulant storm - state health department psychostimulant age-adjusted mortality rate correlates with psychostimulant-based Michigan Poison Center case exposures over time.
Topics: Adult; Amphetamine; Central Nervous System Stimulants; Dextroamphetamine; Drug Overdose; Female; Hum | 2021 |
Emergency department patients with untreated opioid use disorder: A comparison of those seeking versus not seeking referral to substance use treatment.
Topics: Adult; Amphetamine; Baltimore; Cross-Sectional Studies; Drug Overdose; Emergency Service, Hospital; | 2021 |
Association of Medical Stimulants With Mortality in the US From 2010 to 2017.
Topics: Adult; Amphetamine; Central Nervous System Stimulants; Cocaine; Drug Overdose; Female; Humans; Male; | 2021 |
Medico-legal assessment of methamphetamine and amphetamine serum concentrations-what can we learn from survived intoxications?
Topics: Adult; Amphetamine; Body Packing; Driving Under the Influence; Drug Overdose; Gas Chromatography-Mas | 2017 |
Discrimination Between Drug Abuse and Medical Therapy: Case report of a tranylcypromine overdose-related fatality.
Topics: Adult; Amphetamine; Antidepressive Agents; Central Nervous System Stimulants; Depression; Drug Overd | 2017 |
Efficacy of drug screening in forensic autopsy: retrospective investigation of routine toxicological findings.
Topics: Amphetamine; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Autopsy; Chromatograp | 2015 |
Acute chlorophenylpiperazine overdose: a case report and review of the literature.
Topics: Acute Disease; Adult; Amphetamine; Central Nervous System Depressants; Central Nervous System Stimul | 2008 |
Detection of levorotatory methamphetamine and levorotatory amphetamine in urine after ingestion of an overdose of selegiline.
Topics: Adult; Amphetamine; Biomarkers; Drug Overdose; Gas Chromatography-Mass Spectrometry; Humans; Male; M | 2008 |
HIV infection and risk behaviour of primary fentanyl and amphetamine injectors in Tallinn, Estonia: implications for intervention.
Topics: Adult; Amphetamine; Cross-Sectional Studies; Drug Overdose; Estonia; Female; Fentanyl; HIV Infection | 2010 |
[A new designer drug: methylone related death].
Topics: Adolescent; Amphetamine; Asthma; Autopsy; Causality; Death, Sudden, Cardiac; Designer Drugs; Drug Ov | 2012 |
Complicated suicide versus autoeroticism?: a case involving multiple drugs and a porta-potty.
Topics: Adult; Amphetamine; Analgesics, Opioid; Asphyxia; Central Nervous System Stimulants; Disinfectants; | 2013 |
Death and paramethoxyamphetamine - an evolving problem.
Topics: Amphetamine; Amphetamines; Belgium; Disease Outbreaks; Drug Overdose; Female; Humans; Mortality | 2002 |
Overdosage with dexedrine.
Topics: Amphetamine; Amphetamines; Dextroamphetamine; Drug Overdose | 1950 |
The use of amphetamine in gamma-hydroxybutyrate overdose: a case report.
Topics: Adult; Amphetamine; Coma; Drug Interactions; Drug Overdose; Emergencies; Humans; Male; Sodium Oxybat | 2004 |
Underlying causes of cocaine, amphetamine and opioid related deaths in Australia.
Topics: Accidents; Adolescent; Adult; Amphetamine; Australia; Benzodiazepines; Cause of Death; Cocaine; Dopa | 2005 |
Investigative implications of the instability and metabolism of mebeverine.
Topics: Adult; Amphetamine; Anticonvulsants; Chromatography, High Pressure Liquid; Cross Reactions; Drug Ove | 2006 |
Rhabdomyolysis of the masseter muscle: case report.
Topics: Acute Kidney Injury; Adult; Alcoholic Intoxication; Amphetamine; Coma; Drug Overdose; Edema; Face; H | 2008 |
Congenitally corrected transposition of great arteries with ischemic symptoms in middle age.
Topics: Adult; Amphetamine; Central Nervous System Stimulants; Drug Overdose; Humans; Male; Myocardial Ische | 2007 |
Overdose of amphetamine.
Topics: Amphetamine; Amphetamines; Central Nervous System Agents; Drug Overdose | 1949 |
Acute poisonings with drugs of abuse.
Topics: Adult; Alcoholic Intoxication; Amphetamine; Barbiturates; Benzodiazepines; Dronabinol; Drug Overdose | 1995 |
Ecstasy and Whizz at a rave resulting in a major burn plus complications.
Topics: 3,4-Methylenedioxyamphetamine; Adult; Amphetamine; Burns; Designer Drugs; Drug Overdose; Humans; Mal | 1993 |
Amphetamine, not MDMA, is associated with intracranial hemorrhage.
Topics: Amphetamine; Central Nervous System Stimulants; Cerebral Hemorrhage; Drug Overdose; Female; Hallucin | 1995 |
[Fatal neuroleptic malignant syndrome caused by cocaine and amphetamine overdose].
Topics: Adult; Amphetamine; Betaxolol; Central Nervous System Stimulants; Cocaine; Drug Overdose; Fatal Outc | 1996 |
A cluster of fentanyl-related deaths among drug addicts in Sweden.
Topics: Adult; Amphetamine; Analgesics, Opioid; Cause of Death; Chromatography, Gas; Drug Overdose; Fentanyl | 1997 |
[Ecstasy and related drugs in biological materials].
Topics: Amphetamine; Amphetamine-Related Disorders; Drug Overdose; Hallucinogens; Humans; Immunologic Techni | 1999 |
[Poisoning with central nervous system stimulants. Amphetamine, ecstasy, cocaine and gamma-hydroxybutyrate].
Topics: Amphetamine; Amphetamine-Related Disorders; Cocaine; Cocaine-Related Disorders; Denmark; Drug Overdo | 1999 |
Simple and simultaneous analysis of fenfluramine, amphetamine and methamphetamine in whole blood by gas chromatography-mass spectrometry after headspace-solid phase microextraction and derivatization.
Topics: Adult; Amphetamine; Appetite Depressants; Calibration; Central Nervous System Stimulants; Chemical P | 2000 |
[Fatal intracerebral hemorrhage after amphetamine intake].
Topics: Administration, Oral; Adult; Amphetamine; Central Nervous System Stimulants; Cerebral Hemorrhage; Dr | 2000 |
False-positive amphetamine screen following a trazodone overdose.
Topics: Adult; Amphetamine; Antidepressive Agents, Second-Generation; Drug Overdose; False Positive Reaction | 2001 |
Fatalities caused by the MDMA-related drug paramethoxyamphetamine (PMA).
Topics: Adolescent; Adult; Amphetamine; Amphetamines; Autopsy; Central Nervous System Stimulants; Cytochrome | 2001 |
Three cases of fatal paramethoxyamphetamine overdose.
Topics: Adolescent; Adult; Amphetamine; Amphetamines; Autopsy; Central Nervous System Stimulants; Chromatogr | 2001 |