amphetamine has been researched along with Depressive Disorder, Major in 11 studies
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To systematically review the literature on the therapeutic use of amphetamine, lisdexamfetamine and methylphenidate in elderly population with and without dementia." | 5.05 | Amphetamine Use in the Elderly: A Systematic Review of the Literature. ( Colpo, GD; John, V; Rocha, NP; Sassi, KLM; Teixeira, AL, 2020) |
| "The use of traditional psychostimulants (methylphenidate and dexamphetamine) and stimulant-like drugs (modafinil and armodafinil) for the treatment of depression is a growing concern given the lack of research evidence supporting their effectiveness." | 4.93 | Stimulants for depression: On the up and up? ( Bassett, D; Boyce, P; Byrow, Y; Hopwood, M; Lyndon, W; Malhi, GS; Mulder, R; Murray, G; Porter, R; Singh, A, 2016) |
| " However, the relationship between ATS use and mental disorders is complex, with divergent patterns of association for ecstasy and methamphetamine use." | 4.02 | The prevalence of mental health disorders among young adults who use amphetamine-type stimulants, compared to young adults who do not. ( Najman, JM; Pourmarzi, D; Smirnov, A; Thoradeniya, MR; Wessel, EL, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Sassi, KLM | 1 |
| Rocha, NP | 1 |
| Colpo, GD | 1 |
| John, V | 1 |
| Teixeira, AL | 1 |
| Kangas, BD | 1 |
| Wooldridge, LM | 1 |
| Luc, OT | 1 |
| Bergman, J | 1 |
| Pizzagalli, DA | 1 |
| Thoradeniya, MR | 1 |
| Wessel, EL | 1 |
| Pourmarzi, D | 1 |
| Najman, JM | 1 |
| Smirnov, A | 1 |
| Hales, CA | 1 |
| Houghton, CJ | 1 |
| Robinson, ESJ | 1 |
| Homan, P | 1 |
| Drevets, WC | 2 |
| Hasler, G | 2 |
| Malhi, GS | 1 |
| Byrow, Y | 1 |
| Bassett, D | 1 |
| Boyce, P | 1 |
| Hopwood, M | 1 |
| Lyndon, W | 1 |
| Mulder, R | 1 |
| Porter, R | 1 |
| Singh, A | 1 |
| Murray, G | 1 |
| Luckenbaugh, DA | 1 |
| Snow, J | 1 |
| Meyers, N | 1 |
| Waldeck, T | 1 |
| Geraci, M | 1 |
| Roiser, J | 1 |
| Knutson, B | 1 |
| Charney, DS | 1 |
| CLANCY, J | 1 |
| Janowsky, DS | 1 |
| Parsey, RV | 1 |
| Oquendo, MA | 1 |
| Zea-Ponce, Y | 1 |
| Rodenhiser, J | 1 |
| Kegeles, LS | 1 |
| Pratap, M | 1 |
| Cooper, TB | 1 |
| Van Heertum, R | 1 |
| Mann, JJ | 1 |
| Laruelle, M | 1 |
| Mashkovskii, MD | 1 |
| Polezhaeva, AI | 1 |
| Avrutskii, GIa | 1 |
| Vertozgadova, OP | 1 |
| Smulevich, AB | 1 |
3 reviews available for amphetamine and Depressive Disorder, Major
| Article | Year |
|---|---|
Amphetamine Use in the Elderly: A Systematic Review of the Literature.
Topics: Aged; Amphetamine; Dementia; Depressive Disorder, Major; Humans; Lisdexamfetamine Dimesylate; Methyl | 2020 |
Stimulants for depression: On the up and up?
Topics: Amphetamine; Antidepressive Agents; Benzhydryl Compounds; Bipolar Disorder; Central Nervous System S | 2016 |
Depression and dysphoria effects on the interpersonal perception of negative and positive moods and caring relationships: effects of antidepressants, amphetamine, and methylphenidate.
Topics: Amphetamine; Antidepressive Agents; Anxiety Disorders; Central Nervous System Stimulants; Clinical T | 2003 |
2 trials available for amphetamine and Depressive Disorder, Major
| Article | Year |
|---|---|
The effects of catecholamine depletion on the neural response to fearful faces in remitted depression.
Topics: Adolescent; Adult; alpha-Methyltyrosine; Amphetamine; Catecholamines; Central Nervous System Stimula | 2014 |
Reward processing after catecholamine depletion in unmedicated, remitted subjects with major depressive disorder.
Topics: Adolescent; Adult; Amphetamine; Catecholamines; Central Nervous System Stimulants; Cross-Over Studie | 2009 |
6 other studies available for amphetamine and Depressive Disorder, Major
| Article | Year |
|---|---|
Empirical validation of a touchscreen probabilistic reward task in rats.
Topics: Amphetamine; Anhedonia; Animals; Depressive Disorder, Major; Female; Learning; Rats; Reward | 2020 |
The prevalence of mental health disorders among young adults who use amphetamine-type stimulants, compared to young adults who do not.
Topics: Amphetamine; Anxiety Disorders; Australia; Depressive Disorder, Major; Humans; Mania; Mental Disorde | 2021 |
Behavioural and computational methods reveal differential effects for how delayed and rapid onset antidepressants effect decision making in rats.
Topics: Acoustic Stimulation; Amphetamine; Analgesics; Animals; Antidepressive Agents; Association Learning; | 2017 |
OTHER ASPECTS OF DEPRESSION.
Topics: Alcoholism; Amphetamine; Antidepressive Agents; Barbiturates; Bipolar Disorder; Brain Diseases; Depr | 1965 |
Dopamine D(2) receptor availability and amphetamine-induced dopamine release in unipolar depression.
Topics: Adolescent; Adult; Amphetamine; Benzamides; Corpus Striatum; Depressive Disorder, Major; Dopamine; F | 2001 |
[The pharmacologic properties and therapeutic effectiveness of the new antidepressant preparation Azaphen].
Topics: Adult; Aged; Amphetamine; Animals; Antidepressive Agents; Bipolar Disorder; Cats; Depression; Depres | 1969 |