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amphetamine and Depression, Endogenous

amphetamine has been researched along with Depression, Endogenous in 59 studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Research Excerpts

ExcerptRelevanceReference
"Seventy unwed pregnant patients in states of mild to moderate depression evidenced by one or more symptoms (tenseness, "nervousness," crying spells, listlessness, fatigue, nausea and vomiting, insomnia and overeating), received informal psychotherapy and a sustained-release capsule combining d-amphetamine sulfate and amobarbital."7.63Prepartum depression; a study of seventy unwed mothers treated with d-amphetamine sulfate and amobarbital. ( CALDWELL, WG; NOWERS, W, 1958)
"Seventy unwed pregnant patients in states of mild to moderate depression evidenced by one or more symptoms (tenseness, "nervousness," crying spells, listlessness, fatigue, nausea and vomiting, insomnia and overeating), received informal psychotherapy and a sustained-release capsule combining d-amphetamine sulfate and amobarbital."3.63Prepartum depression; a study of seventy unwed mothers treated with d-amphetamine sulfate and amobarbital. ( CALDWELL, WG; NOWERS, W, 1958)
"With the exception of Parkinson's disease, there is little evidence that treatments which decrease DA function are potent inducers of depression, but it is argued that such a relationship might not necessarily be expected."2.36Dopamine and depression: a review of recent evidence. I. Empirical studies. ( Willner, P, 1983)
"Although depressive disorders affect approximately 5% of the population in developed countries each year, current antidepressants usually require several weeks to produce beneficial clinical effects and are only effective in about 55% of patients."1.35Early prediction of the effectiveness of antidepressants: inputs from an animal model. ( Friedman, A; Lax, E; Lubin, N; Merenlender, A; Rosenstein, M; Yadid, G, 2009)
"Priapism is a "persistent erection not accompanied by sexual desire or stimulation, usually lasting more than six hours and typically involving only the corpora cavernosa."1.33Priapism and quetiapine: a case report. ( Dilley, JW; Harrison, G; Loeb, L; Nelson, K, 2006)
"A group of 329 hospitalized drug abusers were evaluated for a current or past diagnosis of alcoholism."1.27A comparison of alcoholic and nonalcoholic drug abusers. ( Griffin, ML; Michael, JL; Mirin, SM; Weiss, RD, 1988)

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-199048 (81.36)18.7374
1990's1 (1.69)18.2507
2000's6 (10.17)29.6817
2010's4 (6.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Furlanetti, LL1
Coenen, VA1
Aranda, IA1
Döbrössy, MD1
Amiri, S1
Alijanpour, S1
Tirgar, F1
Haj-Mirzaian, A1
Amini-Khoei, H1
Rahimi-Balaei, M1
Rastegar, M1
Ghaderi, M1
Ghazi-Khansari, M1
Zarrindast, MR1
Gonzáles, MA1
Miranda, AP1
Orrego, H1
Silva, R1
Forray, MI1
Friedman, A1
Merenlender, A1
Lax, E1
Rosenstein, M1
Lubin, N1
Yadid, G1
Chen, CY1
Lin, KM1
RUDOLF, GD1
Kalinichev, M1
Rouillier, M1
Girard, F1
Royer-Urios, I1
Bournique, B1
Finn, T1
Charvin, D1
Campo, B1
Le Poul, E1
Mutel, V1
Poli, S1
Neale, SA1
Salt, TE1
Lütjens, R1
LEHEW, JL1
ROBERTS, E1
GRAHN, HV2
COHEN, BD1
SENF, R2
HUSTON, PE2
DE RUDOLF, GM1
SETTEL, E1
CALDWELL, WG1
NOWERS, W1
DAVIDOFF, E1
LEMERE, F1
KLIMO, Z1
KARKOSKA, V1
LUKASSIEWICZ, M1
BUSHNELL, LF1
FEIGLEY, DM1
GIBERTI, F2
ROSSI, R2
BATTISTELLA, G1
HARE, EH1
DOMINIAN, J1
SHARPE, L1
STEIN, L1
HARRISON, RM1
BATTERMAN, RC1
FELLNER, CH1
FISCHER, E1
ORLANDO, J1
LUDMER, RL1
PARE, CM1
LEWIS, E1
ANCHERSEN, P1
JOHNSEN, G1
Quinn, PO1
Harrison, G1
Dilley, JW1
Loeb, L1
Nelson, K1
Wallace-Boone, TL1
Newton, AE1
Wright, RN1
Lodge, NJ1
McElroy, JF1
GOTTLIEB, JS1
Luchins, DJ1
Willner, P3
Lake, CR1
Quirk, RS1
Mailman, RB1
Lewis, MH1
Kilts, CD1
Matussek, N1
Belmaker, RH1
Silverstone, T1
Arató, M1
Rihmer, Z1
Bánki, CM1
Grof, P1
Feinberg, M1
Carroll, BJ1
Mashkovskiĭ, MD1
Andreeva, NI1
Silberman, EK1
Reus, VI1
Jimerson, DC1
Lynott, AM1
Post, RM1
Antelman, SM1
Chiodo, LA1
Naranjo, CA1
Tremblay, LK1
Busto, UE1
Swerdlow, NR1
Hauger, R1
Irwin, M1
Koob, GF1
Britton, KT1
Pulvirenti, L1
Gwirtsman, HE1
Guze, BH1
Tibilova, AU1
Alimova, RA1
Chiarello, RJ1
Cole, JO1
Weiss, RD1
Mirin, SM1
Griffin, ML1
Michael, JL1
Siever, LJ1
Insel, TR1
Hamilton, JA1
Aloi, J1
Murphy, DL1

Reviews

9 reviews available for amphetamine and Depression, Endogenous

ArticleYear
Health consequences of illegal drug use.
    Current opinion in psychiatry, 2009, Volume: 22, Issue:3

    Topics: Amphetamine; Depressive Disorder; Health Status; Hepatitis C; Humans; Illicit Drugs; Marijuana Abuse

2009
Dopamine and depression: a review of recent evidence. I. Empirical studies.
    Brain research, 1983, Volume: 287, Issue:3

    Topics: Amphetamine; Antipsychotic Agents; Brain; Bromocriptine; Depressive Disorder; Dihydroxyphenylalanine

1983
Animal models related to developmental disorders: theoretical and pharmacological analyses.
    Applied research in mental retardation, 1981, Volume: 2, Issue:1

    Topics: 5,7-Dihydroxytryptamine; Amphetamine; Animals; Attention Deficit Disorder with Hyperactivity; Brain;

1981
[Neurobiologic aspects of depression].
    Therapeutische Umschau. Revue therapeutique, 1983, Volume: 40, Issue:9

    Topics: Amphetamine; Animals; Blood Platelets; Cholinergic Fibers; Clonidine; Depressive Disorder; Desiprami

1983
Dopamine and depression: a review of recent evidence. III. The effects of antidepressant treatments.
    Brain research, 1983, Volume: 287, Issue:3

    Topics: Amphetamine; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Bra

1983
The clinical pharmacology of appetite--its relevance to psychiatry.
    Psychological medicine, 1983, Volume: 13, Issue:2

    Topics: Amphetamine; Anorexia; Appetite; Bipolar Disorder; Brain Chemistry; Depressive Disorder; Dopamine; F

1983
The validity of animal models of depression.
    Psychopharmacology, 1984, Volume: 83, Issue:1

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Behavior, Animal; Circadian Rhythm; Depressive Disorder;

1984
The role of the brain reward system in depression.
    Progress in neuro-psychopharmacology & biological psychiatry, 2001, Volume: 25, Issue:4

    Topics: Amphetamine; Animals; Brain; Brain Chemistry; Central Nervous System Stimulants; Depressive Disorder

2001
The use of psychostimulants in general psychiatry. A reconsideration.
    Archives of general psychiatry, 1987, Volume: 44, Issue:3

    Topics: Adult; Amphetamine; Central Nervous System Stimulants; Clinical Trials as Topic; Depressive Disorder

1987

Trials

2 trials available for amphetamine and Depression, Endogenous

ArticleYear
Heterogeneity of amphetamine response in depressed patients.
    The American journal of psychiatry, 1981, Volume: 138, Issue:10

    Topics: Adult; Amphetamine; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Huma

1981
The use of psychostimulants in general psychiatry. A reconsideration.
    Archives of general psychiatry, 1987, Volume: 44, Issue:3

    Topics: Adult; Amphetamine; Central Nervous System Stimulants; Clinical Trials as Topic; Depressive Disorder

1987

Other Studies

49 other studies available for amphetamine and Depression, Endogenous

ArticleYear
Chronic deep brain stimulation of the medial forebrain bundle reverses depressive-like behavior in a hemiparkinsonian rodent model.
    Experimental brain research, 2015, Volume: 233, Issue:11

    Topics: Adrenergic Agents; Amphetamine; Animals; Central Nervous System Stimulants; Deep Brain Stimulation;

2015
NMDA receptors are involved in the antidepressant-like effects of capsaicin following amphetamine withdrawal in male mice.
    Neuroscience, 2016, 08-04, Volume: 329

    Topics: Amphetamine; Animals; Antidepressive Agents; Capsaicin; Central Nervous System Stimulants; Depressiv

2016
Enduring attenuation of norepinephrine synaptic availability and augmentation of the pharmacological and behavioral effects of desipramine by repeated immobilization stress.
    Neuropharmacology, 2017, 05-01, Volume: 117

    Topics: Amphetamine; Animals; Antidepressive Agents, Tricyclic; Anxiety; Central Nervous System Stimulants;

2017
Early prediction of the effectiveness of antidepressants: inputs from an animal model.
    Journal of molecular neuroscience : MN, 2009, Volume: 39, Issue:1-2

    Topics: Amphetamine; Animals; Antidepressive Agents; Behavior, Animal; Depressive Disorder; Desipramine; Dop

2009
The effect of amphetamine on fatigue and depression.
    The British journal of addiction to alcohol and other drugs, 1947, Volume: 44, Issue:2

    Topics: Amphetamine; Amphetamines; Depression; Depressive Disorder; Fatigue; Humans

1947
ADX71743, a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7: in vitro and in vivo characterization.
    The Journal of pharmacology and experimental therapeutics, 2013, Volume: 344, Issue:3

    Topics: Allosteric Regulation; Amphetamine; Animals; Anxiety Disorders; Behavior, Animal; Cell Line; Chromos

2013
Amycal comp.
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1953, 02-01, Volume: 73, Issue:3

    Topics: Amphetamine; Amphetamines; Atropa belladonna; Barbiturates; Depression; Depressive Disorder

1953
Evaluation of an amphetamine-barbiturate combination in the supportive treatment of the aged.
    Journal of the American Geriatrics Society, 1954, Volume: 2, Issue:2

    Topics: Aged; Amphetamine; Amphetamines; Anxiety; Barbiturates; Depression; Depressive Disorder; Humans

1954
D'amphetamine therapy in obesity or depression complicated by benign hypertension.
    American practitioner and digest of treatment, 1954, Volume: 5, Issue:8

    Topics: Amphetamine; Amphetamines; Depression; Depressive Disorder; Dextroamphetamine; Humans; Hypertension;

1954
Use of a d-amphetamine-amobarbital combination as an adjunct to the treatment of carcinoma.
    Journal of the American Geriatrics Society, 1954, Volume: 2, Issue:9

    Topics: Amobarbital; Amphetamine; Amphetamines; Anxiety; Barbiturates; Depression; Depressive Disorder; Dext

1954
Perceptual accuracy in schizophrenia, depression, and neurosis, and effects of amytal.
    Journal of abnormal psychology, 1956, Volume: 52, Issue:3

    Topics: Amobarbital; Amphetamine; Amphetamines; Barbiturates; Depression; Depressive Disorder; Humans; Neuro

1956
The treatment of depression with methylamphetamine.
    The Journal of mental science, 1956, Volume: 102, Issue:427

    Topics: Amphetamine; Amphetamines; Depression; Depressive Disorder; Humans; Methamphetamine

1956
Dextro-amphetamine sulfate in mild depression and anxiety.
    International record of medicine and general practice clinics, 1957, Volume: 170, Issue:9

    Topics: Amphetamine; Amphetamines; Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Dextroamphet

1957
Prepartum depression; a study of seventy unwed mothers treated with d-amphetamine sulfate and amobarbital.
    California medicine, 1958, Volume: 88, Issue:5

    Topics: Amobarbital; Amphetamine; Amphetamines; Anxiety; Apathy; Depression; Depressive Disorder; Dextroamph

1958
Effect of combined chlorpromazine and dextro-amphetamine on severely depressed patients.
    Diseases of the nervous system, 1958, Volume: 19, Issue:6

    Topics: Amphetamine; Amphetamines; Chlorpromazine; Depression; Depressive Disorder; Dextroamphetamine; Human

1958
JB-516 and iproniazid.
    The American journal of psychiatry, 1958, Volume: 115, Issue:6

    Topics: Amphetamine; Amphetamines; Depression; Depressive Disorder; Hydrazines; Iproniazid; Niacin; Nicotini

1958
[Treatment of depressive states].
    Ceskoslovenska psychiatrie, 1959, Volume: 55, Issue:1

    Topics: Amphetamine; Amphetamines; Convulsive Therapy; Depression; Depressive Disorder; Electroconvulsive Th

1959
First-trimester depression: a suggested treatment.
    Obstetrics and gynecology, 1961, Volume: 18

    Topics: Amphetamine; Amphetamines; Depression; Depressive Disorder; Female; Humans; Pregnancy; Pregnancy Tri

1961
Office care of mild emotional distress.
    Diseases of the nervous system, 1962, Volume: 23

    Topics: Amobarbital; Amphetamine; Amphetamines; Anxiety; Anxiety Disorders; Atropa belladonna; Depression; D

1962
[Preliminary contribution to the application of a psychopharmacological method of differential diagnostic evaluation of depression].
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1961, Dec-31, Volume: 85

    Topics: Amphetamine; Amphetamines; Central Nervous System; Depression; Depressive Disorder; Diagnosis, Diffe

1961
Proposal of a psychopharmacological test ("stimulation threshold") for differentiating neurotic from psychotic depressions. Preliminary report.
    Psychopharmacologia, 1962, Volume: 3

    Topics: Amphetamine; Amphetamines; Bipolar Disorder; Depression; Depressive Disorder; Humans; Psychotic Diso

1962
Phenelzine and dexamphetamine in depressive illness. A comparative trial.
    British medical journal, 1962, Jan-06, Volume: 1, Issue:5270

    Topics: Amphetamine; Amphetamines; Depression; Depressive Disorder; Dextroamphetamine; Hydrazines; Phenelzin

1962
Effects and interactions of imipramine, chlorpromazine, reserpine and amphetamine on self-stimulation: possible neurophysiological basis of depression.
    Recent advances in biological psychiatry, 1961, Volume: 4

    Topics: Amphetamine; Amphetamines; Chlorpromazine; Depression; Depressive Disorder; Imipramine; Reserpine; S

1961
A double blind trial of a new preparation for the treatment of mild depression encountered in general practice.
    The British journal of clinical practice, 1963, Volume: 17

    Topics: Amphetamine; Antidepressive Agents; Depression; Depressive Disorder; Double-Blind Method; Family Pra

1963
SUSTAINED-ACTION AMPHETAMINE-MEPROBAMATE COMBINATION FOR THE TREATMENT OF OBESITY.
    Current therapeutic research, clinical and experimental, 1964, Volume: 6

    Topics: Amphetamine; Amphetamines; Appetite Depressants; Biomedical Research; Delayed-Action Preparations; D

1964
EARLY RECOGNITION OF DEPRESSION.
    Geriatrics, 1964, Volume: 19

    Topics: Amitriptyline; Amphetamine; Amphetamines; Barbiturates; Benactyzine; Chlordiazepoxide; Deanol; Depre

1964
[EFFECT OF METHYLAMPHETAMINE, IPRONIAZID AND TRANYLCYPROMINE ON ADRENALINE PSYCHOMOTOR DEPRESSION].
    Prensa medica argentina, 1964, Dec-25, Volume: 51

    Topics: Amphetamine; Amphetamines; Animals; Depression; Depressive Disorder; Epinephrine; Iproniazid; Metham

1964
TREATMENT OF DEPRESSION.
    Lancet (London, England), 1965, May-01, Volume: 1, Issue:7392

    Topics: Amphetamine; Amphetamines; Antidepressive Agents; Catecholamines; Depression; Depressive Disorder; D

1965
HYPERPYREXIA WITH ANTIDEPRESSANT DRUGS.
    British medical journal, 1965, Jun-26, Volume: 1, Issue:5451

    Topics: Amphetamine; Amphetamines; Antidepressive Agents; Depression; Depressive Disorder; Drug Therapy; Fev

1965
[Abuse of sedatives, with reference to amycal therapy of depression, etc..].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1952, Mar-01, Volume: 72, Issue:5

    Topics: Amphetamine; Amphetamines; Barbiturates; Depression; Depressive Disorder; Humans; Hypnotics and Seda

1952
Psychopathology of schizophrenia and depression. I. Effect of amytal and amphetamine sulfate on level and maintenance of attention.
    The American journal of psychiatry, 1952, Volume: 109, Issue:2

    Topics: Aged; Amobarbital; Amphetamine; Attention; Depression; Depressive Disorder; Humans; Psychopathology;

1952
[Abuse of amphetamine and hypnotics; reply to Tor Christiansen].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1952, Apr-01, Volume: 72, Issue:7

    Topics: Amphetamine; Amphetamines; Depression; Depressive Disorder; Humans; Hypnotics and Sedatives; Mental

1952
The depressed patient; management with the aid of a new medication.
    American practitioner and digest of treatment, 1950, Volume: 1, Issue:8

    Topics: Amphetamine; Amphetamines; Barbital; Depression; Depressive Disorder; Disease Management

1950
Treating adolescent girls and women with ADHD: gender-specific issues.
    Journal of clinical psychology, 2005, Volume: 61, Issue:5

    Topics: Adolescent; Adult; Age Factors; Amphetamine; Anxiety Disorders; Attention Deficit Disorder with Hype

2005
Priapism and quetiapine: a case report.
    Psychopharmacology bulletin, 2006, Volume: 39, Issue:1

    Topics: Amphetamine; Amphetamine-Related Disorders; Antipsychotic Agents; Comorbidity; Depressive Disorder;

2006
Behavioral and pharmacological validation of the gerbil forced-swim test: effects of neurokinin-1 receptor antagonists.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:8

    Topics: Adrenergic Uptake Inhibitors; Amphetamine; Animals; Antidepressive Agents; Antidepressive Agents, Se

2008
The use of sodium amytal and benzedrine sulfate in the symptomatic treatment of depressions.
    Diseases of the nervous system, 1949, Volume: 10, Issue:2

    Topics: Amobarbital; Amphetamine; Depression; Depressive Disorder; Sulfates; Sulfur Oxides

1949
Developments in biological psychiatry: clinical applications to the major psychoses.
    Hospital & community psychiatry, 1982, Volume: 33, Issue:5

    Topics: Amphetamine; Antidepressive Agents; Depressive Disorder; Dexamethasone; Diagnosis, Differential; Hum

1982
CNS stimulants and the look-alike drugs.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:4

    Topics: Amphetamine; Caffeine; Central Nervous System Stimulants; Depressive Disorder; Ephedrine; Humans; Il

1984
Adenylate cyclase and the search for new compounds with the clinical profile of lithium.
    Pharmacopsychiatry, 1984, Volume: 17, Issue:1

    Topics: Adenylyl Cyclases; Albuterol; Amphetamine; Antidepressive Agents; Brain; Cyclic AMP; Demeclocycline;

1984
The relationships of neuroendocrine tests in endogenous depression.
    Progress in neuro-psychopharmacology & biological psychiatry, 1983, Volume: 7, Issue:4-6

    Topics: Adult; Amphetamine; Depressive Disorder; Dexamethasone; Female; Growth Hormone; Humans; Hydrocortiso

1983
Biological markers for endogenous depression in series and parallel.
    Biological psychiatry, 1984, Volume: 19, Issue:1

    Topics: Amphetamine; Bipolar Disorder; Depressive Disorder; Dexamethasone; Electroencephalography; Growth Ho

1984
[Experimental and clinical characteristics of the Soviet antidepressant inkasan].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1984, Volume: 84, Issue:3

    Topics: Amphetamine; Animals; Antidepressive Agents; Apomorphine; Biogenic Amines; Brain; Carbolines; Cats;

1984
Dopamine autoreceptor subsensitivity: a mechanism common to the treatment of depression and the induction of amphetamine psychosis.
    Biological psychiatry, 1981, Volume: 16, Issue:8

    Topics: Amitriptyline; Amphetamine; Animals; Antidepressive Agents, Tricyclic; Apomorphine; Depressive Disor

1981
Endocrine, immune, and neurochemical changes in rats during withdrawal from chronic amphetamine intoxication.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1991, Volume: 5, Issue:1

    Topics: Adrenocorticotropic Hormone; Amphetamine; Animals; Biomarkers; Body Weight; Brain Chemistry; Cortico

1991
Amphetamine, but not methylphenidate, predicts antidepressant response.
    Journal of clinical psychopharmacology, 1989, Volume: 9, Issue:6

    Topics: Amphetamine; Antidepressive Agents; Depressive Disorder; Humans; Methylphenidate; Prognosis

1989
[Problem of transient dementias of old age (clinico-diagnostic aspect)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1985, Volume: 85, Issue:9

    Topics: Aged; Amphetamine; Anxiety; Central Nervous System Stimulants; Dementia; Depressive Disorder; Diagno

1985
A comparison of alcoholic and nonalcoholic drug abusers.
    Journal of studies on alcohol, 1988, Volume: 49, Issue:6

    Topics: Adult; Alcoholism; Amphetamine; Bipolar Disorder; Cocaine; Depressive Disorder; Female; Humans; Hypn

1988
A comparison between the growth hormone responses to amphetamine and clonidine.
    Psychiatry research, 1985, Volume: 16, Issue:1

    Topics: Adult; Amphetamine; Clonidine; Depressive Disorder; Growth Hormone; Humans; Obsessive-Compulsive Dis

1985