Page last updated: 2024-10-25

amphetamine and Dementia

amphetamine has been researched along with Dementia in 8 studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.

Research Excerpts

ExcerptRelevanceReference
"L-dopa responsive parkinsonism could be an initial manifestation of Alzheimer's disease, which should be included in the differential diagnosis."5.40An 85-year old male with levodopa-responsive parkinsonism followed by dementia and supranuclear ophthalmoplegia caused by alzheimer-type pathology without Lewy bodies. ( Hagiwara, M; Kasahata, N; Kato, H; Nakamura, A; Uchihara, T, 2014)
"To systematically review the literature on the therapeutic use of amphetamine, lisdexamfetamine and methylphenidate in elderly population with and without dementia."5.05Amphetamine Use in the Elderly: A Systematic Review of the Literature. ( Colpo, GD; John, V; Rocha, NP; Sassi, KLM; Teixeira, AL, 2020)
"One hundred ten patients with alcohol dependence and 56 psychiatric patients with either senile dementia, amphetamine psychosis, epilepsy or chronic schizophrenia were investigated with a CT scan of the brain."3.68Computerized tomographic study on the brain of patients with alcohol dependence. ( Kato, A; Nakajima, T; Nakamura, M; Tsuji, M, 1991)
"L-dopa responsive parkinsonism could be an initial manifestation of Alzheimer's disease, which should be included in the differential diagnosis."1.40An 85-year old male with levodopa-responsive parkinsonism followed by dementia and supranuclear ophthalmoplegia caused by alzheimer-type pathology without Lewy bodies. ( Hagiwara, M; Kasahata, N; Kato, H; Nakamura, A; Uchihara, T, 2014)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's1 (12.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Sassi, KLM1
Rocha, NP1
Colpo, GD1
John, V1
Teixeira, AL1
Kasahata, N1
Hagiwara, M1
Kato, H1
Nakamura, A1
Uchihara, T1
BLACKMAN, LH2
GLENN, A2
OLINGER, L2
Reisberg, B1
Ferris, SH1
Gershon, S1
Kato, A1
Tsuji, M1
Nakamura, M1
Nakajima, T1
Tibilova, AU1
Alimova, RA1
Pohl, P1
Vogl, G1
Fill, H1
Rössler, H1
Zangerle, R1
Gerstenbrand, F1

Reviews

2 reviews available for amphetamine and Dementia

ArticleYear
Amphetamine Use in the Elderly: A Systematic Review of the Literature.
    Current neuropharmacology, 2020, Volume: 18, Issue:2

    Topics: Aged; Amphetamine; Dementia; Depressive Disorder, Major; Humans; Lisdexamfetamine Dimesylate; Methyl

2020
Pharmacotherapy of senile dementia.
    Proceedings of the annual meeting of the American Psychopathological Association, 1980, Volume: 69

    Topics: Adult; Age Factors; Aged; Alzheimer Disease; Amphetamine; Antidepressive Agents, Tricyclic; Dementia

1980

Other Studies

6 other studies available for amphetamine and Dementia

ArticleYear
An 85-year old male with levodopa-responsive parkinsonism followed by dementia and supranuclear ophthalmoplegia caused by alzheimer-type pathology without Lewy bodies.
    Journal of Alzheimer's disease : JAD, 2014, Volume: 39, Issue:3

    Topics: Aged, 80 and over; Alzheimer Disease; Amphetamine; Dementia; Humans; Imaging, Three-Dimensional; Lev

2014
The use of vitarespital in the treatment of elderly psychotic patients.
    International record of medicine and general practice clinics, 1958, Volume: 171, Issue:1

    Topics: Amphetamine; Amphetamines; Dementia; Humans; Mental Disorders; Psychotic Disorders; Reserpine; Vitam

1958
The combination of tranquilizer, sympathomimetic drug and vitamins in the treatment of elderly psychotic patients.
    Journal of the American Geriatrics Society, 1958, Volume: 6, Issue:7

    Topics: Amphetamine; Amphetamines; Dementia; Humans; Hypnotics and Sedatives; Mental Disorders; Psychotic Di

1958
Computerized tomographic study on the brain of patients with alcohol dependence.
    The Japanese journal of psychiatry and neurology, 1991, Volume: 45, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Withdrawal Delirium; Alcoholism; Amphetamine; Atrophy; Brain

1991
[Problem of transient dementias of old age (clinico-diagnostic aspect)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1985, Volume: 85, Issue:9

    Topics: Aged; Amphetamine; Anxiety; Central Nervous System Stimulants; Dementia; Depressive Disorder; Diagno

1985
Single photon emission computed tomography in AIDS dementia complex.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1988, Volume: 29, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Adult; Amphetamine; Brain; Dementia; Diagnosis, Differential; El

1988