amphetamine has been researched along with Delayed Effects, Prenatal Exposure in 91 studies
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "As a test of plausibility for the hypothesis that schizophrenia can result from abnormal brain, especially cerebral cortical, development, these studies examined whether, in the rat, disruption of brain development initiated on embryonic day (E) 17, using the methylating agent methylazoxymethanol acetate (MAM), leads to a schizophrenia-relevant pattern of neural and behavioral pathology." | 7.73 | A neurobehavioral systems analysis of adult rats exposed to methylazoxymethanol acetate on E17: implications for the neuropathology of schizophrenia. ( Geyer, MA; Ghajarnia, M; Grace, AA; Jentsch, JD; Moore, H, 2006) |
| "Psychosocial factors that could be used as predictive indicators for adjustment of 4-year-old children whose mothers had used amphetamine during pregnancy were studied by means of simple and multivariate correlation analyses." | 7.67 | Predictive indicators for adjustment in 4-year-old children whose mothers used amphetamine during pregnancy. ( Billing, L; Eriksson, M; Steneroth, G; Zetterström, R, 1988) |
| "Schizophrenia is believed to arise from an interaction of genetic predisposition and adverse environmental factors, with stress being a primary variable." | 5.39 | Peripubertal diazepam administration prevents the emergence of dopamine system hyperresponsivity in the MAM developmental disruption model of schizophrenia. ( Du, Y; Grace, AA, 2013) |
| "The present analysis indicates that the literature is currently too limited to draw anything but very tentative conclusions about whether amphetamine during pregnancy is detrimental to the offspring." | 4.77 | Prenatal amphetamine effects on behavior: possible mediation by brain monoamines. ( Middaugh, LD, 1989) |
| "The methylazoxymethanol acetate (MAM) rodent neurodevelopmental model of schizophrenia exhibits aberrant dopamine system activation attributed to hippocampal dysfunction." | 3.88 | Impaired contextual fear-conditioning in MAM rodent model of schizophrenia. ( Gill, KM; Grace, AA; Miller, SA, 2018) |
| "Methamphetamine (METH) abuse is a growing health problem worldwide, and METH use during pregnancy not only endangers the mother's health but also the developing fetus." | 3.80 | Sex differences in methamphetamine pharmacokinetics in adult rats and its transfer to pups through the placental membrane and breast milk. ( Bubenikova-Valesova, V; Bumba, J; Kacer, P; Rambousek, L; Slamberova, R; Syslova, K, 2014) |
| " Furthermore, the presence or absence of maternal weight loss predicted MK-801 and amphetamine stimulated locomotor abnormalities in offspring." | 3.77 | Individual differences in maternal response to immune challenge predict offspring behavior: contribution of environmental factors. ( Ahlbrand, R; Bronson, SL; Horn, PS; Kern, JR; Richtand, NM, 2011) |
| " Post-weaning exposure to SD increased body weight, body fat, and plasma leptin levels, as well as the plasma glucose response to glucose challenge, compared to chow-fed rats." | 3.76 | Long-term physiological and behavioral effects of exposure to a highly palatable diet during the perinatal and post-weaning periods. ( Frate, C; Schuster, K; Shalev, U; Tobin, S; Tylor, A; Woodside, B, 2010) |
| "To determine the effect of prenatal lead exposure on brain monoaminergic systems, pregnant rats were given tap water containing 250 ppm lead acetate, for the duration of pregnancy, while tap water without lead (Pb(2+)) was substituted at birth." | 3.74 | Maternal lead exposure produces long-term enhancement of dopaminergic reactivity in rat offspring. ( Brus, R; Kostrzewa, RM; Nowak, P; Szczerbak, G, 2007) |
| "As a test of plausibility for the hypothesis that schizophrenia can result from abnormal brain, especially cerebral cortical, development, these studies examined whether, in the rat, disruption of brain development initiated on embryonic day (E) 17, using the methylating agent methylazoxymethanol acetate (MAM), leads to a schizophrenia-relevant pattern of neural and behavioral pathology." | 3.73 | A neurobehavioral systems analysis of adult rats exposed to methylazoxymethanol acetate on E17: implications for the neuropathology of schizophrenia. ( Geyer, MA; Ghajarnia, M; Grace, AA; Jentsch, JD; Moore, H, 2006) |
| "003) in pups born to mothers who were stressed during pregnancy by injections of either saline or amphetamine in saline." | 3.72 | Very mild stress of pregnant rats reduces volume and cell number in nucleus accumbens of adult offspring: some parallels to schizophrenia. ( Ishtoyan, A; Lyon, M; McClure, WO, 2004) |
| "Psychosocial factors that could be used as predictive indicators for adjustment of 4-year-old children whose mothers had used amphetamine during pregnancy were studied by means of simple and multivariate correlation analyses." | 3.67 | Predictive indicators for adjustment in 4-year-old children whose mothers used amphetamine during pregnancy. ( Billing, L; Eriksson, M; Steneroth, G; Zetterström, R, 1988) |
| "Oxazepam treatment of primiparous mouse dams on days 12-16 of pregnancy (15 mg/kg p." | 3.67 | Prenatal benzodiazepine effects in mice: postnatal behavioral development, response to drug challenges, and adult discrimination learning. ( Alleva, E; Bignami, G, 1986) |
| "Various stressors (laparotomy, cold or amphetamine injection) applied during the last third of pregnancy resulted in an increase of corticosterone level in mothers and a decrease of the response to emotional stressor (restriction) in their adult offspring." | 3.67 | Stress in early ontogenesis and reactivity of hypothalamo-pituitary-adrenal system in adult rats. ( Maslova, LN; Naumenko, EV, 1985) |
| "A benzodiazepine (oxazepam) was given to nulliparous mice on days 12-16 of pregnancy, and the development and young adult behaviour of the offspring were studied." | 3.67 | Short-, medium-, and long-term effects of prenatal oxazepam on neurobehavioural development of mice. ( Alleva, E; Bignami, G; Laviola, G; Tirelli, E, 1985) |
| "Amphetamines evaluated were D- and D,L-amphetamine and methamphetamine." | 2.43 | NTP-CERHR monograph on the potential human reproductive and developmental effects of amphetamines. ( , 2005) |
| "Individuals with fetal alcohol spectrum disorder (FASD) are at increased risk for substance use disorders (SUD)." | 1.42 | Amphetamine sensitization and cross-sensitization with acute restraint stress: impact of prenatal alcohol exposure in male and female rats. ( Bodnar, T; Comeau, WL; Galea, LA; Uban, KA; Weinberg, J; Yu, WK, 2015) |
| "Schizophrenia is believed to arise from an interaction of genetic predisposition and adverse environmental factors, with stress being a primary variable." | 1.39 | Peripubertal diazepam administration prevents the emergence of dopamine system hyperresponsivity in the MAM developmental disruption model of schizophrenia. ( Du, Y; Grace, AA, 2013) |
| "One of the most common drug abused by pregnant women is methamphetamine (MA), which is also the most frequently abused illicit drug in the Czech Republic." | 1.38 | Do prenatally methamphetamine-exposed adult male rats display general predisposition to drug abuse in the conditioned place preference test? ( Hrubá, L; Macúchová, E; Nová, E; Pometlová, M; Rokyta, R; Schutová, B; Šlamberová, R, 2012) |
| " At 7 weeks of age, dose-response curves were obtained with morphine (10, 31." | 1.30 | Influence of chronic prenatal and postnatal administration of naltrexone in locomotor activity induced by morphine in mice. ( Luján Estrada, M; Medina Jiménez, M; Rodríguez, R, 1997) |
| "This case report is the first to reveal holoprosencephaly and trisomy 13, with maternal early gestational abuse of amphetamine." | 1.29 | Holoprosencephaly and trisomy 13 in a fetus with maternal early gestational amphetamine abuse--a case report. ( Chai, CY; Chao, MC; Lee, JN; Tsai, EM, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (12.09) | 18.7374 |
| 1990's | 15 (16.48) | 18.2507 |
| 2000's | 20 (21.98) | 29.6817 |
| 2010's | 43 (47.25) | 24.3611 |
| 2020's | 2 (2.20) | 2.80 |
| Authors | Studies |
|---|---|
| Stollenwerk, TM | 1 |
| Hillard, CJ | 1 |
| Perez-Palomar, B | 1 |
| Erdozain, AM | 1 |
| Erkizia-Santamaría, I | 1 |
| Ortega, JE | 1 |
| Meana, JJ | 1 |
| Gallant, S | 1 |
| Welch, L | 1 |
| Martone, P | 1 |
| Shalev, U | 2 |
| Gill, KM | 1 |
| Miller, SA | 1 |
| Grace, AA | 6 |
| Wang, R | 2 |
| Shen, YL | 3 |
| Hausknecht, KA | 2 |
| Chang, L | 1 |
| Haj-Dahmane, S | 3 |
| Vezina, P | 3 |
| Shen, RY | 5 |
| Gray, A | 1 |
| Tattoli, R | 1 |
| Dunn, A | 1 |
| Hodgson, DM | 1 |
| Michie, PT | 1 |
| Harms, L | 1 |
| Perez, SM | 2 |
| Donegan, JJ | 1 |
| Lodge, DJ | 3 |
| Du, Y | 1 |
| Willi, R | 1 |
| Harmeier, A | 1 |
| Giovanoli, S | 2 |
| Meyer, U | 4 |
| Rambousek, L | 1 |
| Kacer, P | 1 |
| Syslova, K | 1 |
| Bumba, J | 1 |
| Bubenikova-Valesova, V | 1 |
| Slamberova, R | 5 |
| Macúchová, E | 2 |
| Nohejlová, K | 1 |
| Hausknecht, K | 1 |
| Dlugos, C | 1 |
| Uban, KA | 1 |
| Comeau, WL | 1 |
| Bodnar, T | 1 |
| Yu, WK | 1 |
| Weinberg, J | 1 |
| Galea, LA | 1 |
| Pase, CS | 1 |
| Roversi, K | 2 |
| Trevizol, F | 1 |
| Kuhn, FT | 1 |
| Dias, VT | 1 |
| Vey, LT | 1 |
| Antoniazzi, CT | 1 |
| Barcelos, RC | 1 |
| Bürger, ME | 1 |
| McDonnell-Dowling, K | 1 |
| Kelly, JP | 1 |
| Gomes, FV | 1 |
| Guimarães, FS | 1 |
| Richetto, J | 2 |
| Labouesse, MA | 1 |
| Poe, MM | 1 |
| Cook, JM | 1 |
| Riva, MA | 2 |
| Chou, S | 1 |
| Jones, S | 1 |
| Li, M | 1 |
| Batinić, B | 1 |
| Santrač, A | 1 |
| Divović, B | 1 |
| Timić, T | 1 |
| Stanković, T | 1 |
| Obradović, ALj | 1 |
| Joksimović, S | 1 |
| Savić, MM | 1 |
| Buschert, J | 1 |
| Sakalem, ME | 1 |
| Saffari, R | 1 |
| Hohoff, C | 1 |
| Rothermundt, M | 1 |
| Arolt, V | 1 |
| Zhang, W | 1 |
| Ambrée, O | 1 |
| Engler, H | 1 |
| Engler, A | 1 |
| Feldon, J | 2 |
| Schedlowski, M | 1 |
| Silvagni, A | 2 |
| Barros, VG | 2 |
| Mura, C | 2 |
| Antonelli, MC | 2 |
| Carboni, E | 2 |
| Spoerri, E | 1 |
| Yee, BK | 1 |
| Schwarz, MJ | 1 |
| Björklund, O | 1 |
| Halldner-Henriksson, L | 1 |
| Yang, J | 1 |
| Eriksson, TM | 1 |
| Jacobson, MA | 1 |
| Daré, E | 1 |
| Fredholm, BB | 1 |
| Thompson, BL | 1 |
| Levitt, P | 2 |
| Stanwood, GD | 2 |
| Kleinhaus, K | 1 |
| Steinfeld, S | 1 |
| Balaban, J | 1 |
| Goodman, L | 1 |
| Craft, TS | 1 |
| Malaspina, D | 1 |
| Myers, MM | 1 |
| Moore, H | 2 |
| Smith, AM | 1 |
| Chen, WJ | 1 |
| Ibba, M | 1 |
| Tylor, A | 1 |
| Schuster, K | 1 |
| Frate, C | 1 |
| Tobin, S | 1 |
| Woodside, B | 1 |
| Naef, L | 1 |
| Moquin, L | 1 |
| Dal Bo, G | 1 |
| Giros, B | 1 |
| Gratton, A | 1 |
| Walker, CD | 1 |
| Terplan, M | 1 |
| Wright, T | 1 |
| Bronson, SL | 3 |
| Ahlbrand, R | 4 |
| Horn, PS | 2 |
| Kern, JR | 1 |
| Richtand, NM | 5 |
| Horn, P | 2 |
| Stanford, K | 1 |
| McNamara, RK | 2 |
| Muhammad, A | 1 |
| Kolb, B | 1 |
| Flores, G | 2 |
| de Jesús Gómez-Villalobos, M | 1 |
| Rodríguez-Sosa, L | 1 |
| Schutová, B | 2 |
| Hrubá, L | 2 |
| Pometlová, M | 2 |
| Piontkewitz, Y | 1 |
| Arad, M | 1 |
| Weiner, I | 2 |
| Chambers, B | 1 |
| Davis, J | 1 |
| Benoit, S | 1 |
| Tambyraja, R | 1 |
| Grainger, M | 1 |
| Vorhees, CV | 1 |
| Graham, DL | 1 |
| Braun, AA | 1 |
| Schaefer, TL | 1 |
| Skelton, MR | 1 |
| Williams, MT | 1 |
| Zager, A | 1 |
| Mennecier, G | 1 |
| Palermo-Neto, J | 1 |
| Bocarsly, ME | 1 |
| Barson, JR | 1 |
| Hauca, JM | 1 |
| Hoebel, BG | 1 |
| Leibowitz, SF | 1 |
| Avena, NM | 1 |
| Nová, E | 1 |
| Rokyta, R | 1 |
| Yamamotová, A | 1 |
| Shah, A | 1 |
| Asher, A | 1 |
| Wilson, CA | 1 |
| Terry, AV | 1 |
| Zuckerman, L | 1 |
| Rehavi, M | 1 |
| Nachman, R | 1 |
| Juárez, I | 1 |
| Silva-Gómez, AB | 1 |
| Peralta, F | 1 |
| Choong, KC | 1 |
| McClure, WO | 1 |
| Ishtoyan, A | 1 |
| Lyon, M | 1 |
| Wiley, JL | 1 |
| Compton, AD | 1 |
| Sandner, G | 1 |
| Silva, RC | 1 |
| Angst, MJ | 1 |
| Knobloch, J | 1 |
| Danion, JM | 1 |
| Koenig, JI | 1 |
| Elmer, GI | 1 |
| Shepard, PD | 1 |
| Lee, PR | 1 |
| Mayo, C | 1 |
| Joy, B | 1 |
| Hercher, E | 1 |
| Brady, DL | 1 |
| Jentsch, JD | 1 |
| Ghajarnia, M | 1 |
| Geyer, MA | 1 |
| McBride, SM | 1 |
| Culver, B | 1 |
| Flynn, FW | 1 |
| Szczerbak, G | 2 |
| Nowak, P | 2 |
| Kostrzewa, RM | 2 |
| Brus, R | 2 |
| Nitka, D | 1 |
| Sitkiewicz, T | 1 |
| Ramirez, OA | 1 |
| Keller, EA | 2 |
| Orsingher, OA | 2 |
| Spear, LP | 1 |
| Brake, SC | 1 |
| Diaz, R | 1 |
| Ogren, SO | 1 |
| Blum, M | 1 |
| Fuxe, K | 1 |
| Henry, C | 1 |
| Guegant, G | 1 |
| Cador, M | 1 |
| Arnauld, E | 1 |
| Arsaut, J | 1 |
| Le Moal, M | 1 |
| Demotes-Mainard, J | 1 |
| Tsai, EM | 1 |
| Lee, JN | 1 |
| Chao, MC | 1 |
| Chai, CY | 1 |
| Dell'Omo, G | 1 |
| Fiore, M | 1 |
| Petruzzi, S | 1 |
| Alleva, E | 4 |
| Bignami, G | 3 |
| Simansky, KJ | 1 |
| Kachelries, WJ | 1 |
| Tavares, MA | 2 |
| Silva, MC | 2 |
| Silva-Araújo, A | 1 |
| Xavier, MR | 1 |
| Ali, SF | 2 |
| Inderbitzin, S | 1 |
| Lauber, ME | 1 |
| Schlumpf, M | 1 |
| Lichtensteiger, W | 1 |
| Medina Jiménez, M | 1 |
| Luján Estrada, M | 1 |
| Rodríguez, R | 1 |
| Snyder-Keller, A | 1 |
| Keller, RW | 1 |
| Cagiano, R | 2 |
| Ancona, D | 1 |
| Cassano, T | 1 |
| Tattoli, M | 2 |
| Trabace, L | 2 |
| Cuomo, V | 2 |
| Du, W | 1 |
| Aloyo, VJ | 1 |
| Pazdelski, PS | 1 |
| Harvey, JA | 1 |
| Glatt, SJ | 1 |
| Bolaños, CA | 1 |
| Trksak, GH | 1 |
| Crowder-Dupont, C | 1 |
| Jackson, D | 1 |
| Xu, C | 1 |
| Gaetani, S | 1 |
| Ghiglieri, V | 1 |
| Giustino, A | 1 |
| Mereu, G | 1 |
| Halmesmäki, E | 1 |
| Kari, A | 1 |
| Bortolozzi, A | 1 |
| Duffard, R | 1 |
| Antonelli, M | 1 |
| Evangelista de Duffard, AM | 1 |
| Laviola, G | 2 |
| Pick, CG | 1 |
| Yanai, J | 1 |
| Lall, SB | 1 |
| Sahoo, RN | 1 |
| Scalzo, FM | 1 |
| Holson, RR | 1 |
| Gough, BJ | 1 |
| Middaugh, LD | 1 |
| Fride, E | 1 |
| Weinstock, M | 1 |
| Billing, L | 1 |
| Eriksson, M | 1 |
| Steneroth, G | 1 |
| Zetterström, R | 1 |
| Brioni, JD | 1 |
| Levin, LE | 1 |
| Córdoba, N | 1 |
| Wagner, GC | 1 |
| Jarvis, MF | 1 |
| Gottesfeld, DS | 1 |
| Giorlando, M | 1 |
| Rabii, J | 1 |
| Naumenko, EV | 1 |
| Maslova, LN | 1 |
| Tirelli, E | 1 |
6 reviews available for amphetamine and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Sources of variation in the design of preclinical studies assessing the effects of amphetamine-type stimulants in pregnancy and lactation.
Topics: Amphetamine; Amphetamines; Animals; Animals, Newborn; Central Nervous System Stimulants; Disease Mod | 2015 |
Prenatal exposure to drugs: effects on brain development and implications for policy and education.
Topics: Alcohols; Amphetamine; Antidepressive Agents; Brain; Child; Crack Cocaine; Drug-Related Side Effects | 2009 |
NTP-CERHR monograph on the potential human reproductive and developmental effects of amphetamines.
Topics: Amphetamine; Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Central Nervo | 2005 |
Periadolescence: age-dependent behavior and psychopharmacological responsivity in rats.
Topics: Age Factors; Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain; Cocaine; Exploratory Behavi | 1983 |
[Drugs and pregnancy].
Topics: Amphetamine; Cannabis; Cocaine; Female; Fetus; Hallucinogens; Humans; Illicit Drugs; Narcotics; Preg | 1998 |
Prenatal amphetamine effects on behavior: possible mediation by brain monoamines.
Topics: Amphetamine; Animals; Behavior, Animal; Brain; Catecholamines; Dopamine; Female; Norepinephrine; Pre | 1989 |
85 other studies available for amphetamine and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Adolescent THC Treatment Does Not Potentiate the Behavioral Effects in Adulthood of Maternal Immune Activation.
Topics: Aging; Amphetamine; Animals; Behavior, Animal; Conditioning, Classical; Dronabinol; Extinction, Psyc | 2021 |
Maternal Immune Activation Induces Cortical Catecholaminergic Hypofunction and Cognitive Impairments in Offspring.
Topics: Amphetamine; Animals; Brain; Cognitive Dysfunction; Disease Models, Animal; Dopamine; Female; Humans | 2023 |
Effects of chronic prenatal MK-801 treatment on object recognition, cognitive flexibility, and drug-induced locomotor activity in juvenile and adult rat offspring.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Cognition; Dizocilpine Maleate; Dose-Respon | 2017 |
Impaired contextual fear-conditioning in MAM rodent model of schizophrenia.
Topics: Action Potentials; Amphetamine; Animals; Central Nervous System Stimulants; Conditioning, Classical; | 2018 |
Prenatal ethanol exposure increases risk of psychostimulant addiction.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Behavior, Addictive; Central Nervous System Sti | 2019 |
Maternal immune activation in mid-late gestation alters amphetamine sensitivity and object recognition, but not other schizophrenia-related behaviours in adult rats.
Topics: Amphetamine; Animals; Behavior, Animal; Disease Models, Animal; Female; Male; Maternal Exposure; Mot | 2019 |
Environmental enrichment reverses increased addiction risk caused by prenatal ethanol exposure.
Topics: Amphetamine; Animals; Animals, Newborn; Behavior, Addictive; Environment; Ethanol; Female; Male; Pre | 2018 |
Effect of estrous cycle on schizophrenia-like behaviors in MAM exposed rats.
Topics: Amphetamine; Animals; Behavior, Animal; Disease Models, Animal; Estrous Cycle; Female; Hippocampus; | 2019 |
Peripubertal diazepam administration prevents the emergence of dopamine system hyperresponsivity in the MAM developmental disruption model of schizophrenia.
Topics: Amphetamine; Animals; Anxiety; Central Nervous System Sensitization; Diazepam; Dopaminergic Neurons; | 2013 |
Altered GSK3β signaling in an infection-based mouse model of developmental neuropsychiatric disease.
Topics: Amphetamine; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glycogen Syn | 2013 |
Sex differences in methamphetamine pharmacokinetics in adult rats and its transfer to pups through the placental membrane and breast milk.
Topics: Amphetamine; Animals; Brain Chemistry; Central Nervous System Stimulants; Female; Male; Methamphetam | 2014 |
Gender differences in the effect of adult amphetamine on cognitive functions of rats prenatally exposed to methamphetamine.
Topics: Age Factors; Amphetamine; Animals; Central Nervous System Stimulants; Cognition; Female; Male; Maze | 2014 |
Excitatory synaptic function and plasticity is persistently altered in ventral tegmental area dopamine neurons after prenatal ethanol exposure.
Topics: Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Biophysics; Central Nervous System De | 2015 |
Amphetamine sensitization and cross-sensitization with acute restraint stress: impact of prenatal alcohol exposure in male and female rats.
Topics: Acute Disease; Amphetamine; Animals; Central Nervous System Stimulants; Dopamine; Dose-Response Rela | 2015 |
Chronic consumption of trans fat can facilitate the development of hyperactive behavior in rats.
Topics: Adaptation, Psychological; Akathisia, Drug-Induced; Amphetamine; Animals; Central Nervous System Sti | 2015 |
Effects of pubertal cannabinoid administration on attentional set-shifting and dopaminergic hyper-responsivity in a developmental disruption model of schizophrenia.
Topics: Amphetamine; Animals; Attention; Benzoxazines; Cannabinoids; Central Nervous System Stimulants; Dise | 2014 |
Behavioral effects of the benzodiazepine-positive allosteric modulator SH-053-2'F-S-CH₃ in an immune-mediated neurodevelopmental disruption model.
Topics: Amphetamine; Animals; Benzodiazepines; Central Nervous System Stimulants; Cognition Disorders; Disea | 2015 |
Adolescent olanzapine sensitization is correlated with hippocampal stem cell proliferation in a maternal immune activation rat model of schizophrenia.
Topics: Amphetamine; Animals; Animals, Newborn; Antipsychotic Agents; Avoidance Learning; Benzodiazepines; C | 2015 |
Lipopolysaccharide exposure during late embryogenesis results in diminished locomotor activity and amphetamine response in females and spatial cognition impairment in males in adult, but not adolescent rat offspring.
Topics: Amphetamine; Animals; Autistic Disorder; Behavior, Animal; Cognition; Disease Models, Animal; Female | 2016 |
Prenatal immune activation in mice blocks the effects of environmental enrichment on exploratory behavior and microglia density.
Topics: Age Factors; Amphetamine; Analysis of Variance; Animals; Brain; Central Nervous System Stimulants; C | 2016 |
Preventive effects of minocycline in a neurodevelopmental two-hit model with relevance to schizophrenia.
Topics: Amphetamine; Animals; Anti-Inflammatory Agents; Central Nervous System Stimulants; Disease Models, A | 2016 |
Prenatal restraint stress differentially modifies basal and stimulated dopamine and noradrenaline release in the nucleus accumbens shell: an 'in vivo' microdialysis study in adolescent and young adult rats.
Topics: Adolescent; Adult; Amphetamine; Animals; Child; Dopamine; Dopamine Uptake Inhibitors; Female; Humans | 2008 |
Evaluating early preventive antipsychotic and antidepressant drug treatment in an infection-based neurodevelopmental mouse model of schizophrenia.
Topics: Age Factors; Amphetamine; Animals; Animals, Newborn; Antidepressive Agents, Second-Generation; Antip | 2010 |
Decreased behavioral activation following caffeine, amphetamine and darkness in A3 adenosine receptor knock-out mice.
Topics: Amphetamine; Analysis of Variance; Animals; Caffeine; Central Nervous System Stimulants; Darkness; E | 2008 |
Effects of excessive glucocorticoid receptor stimulation during early gestation on psychomotor and social behavior in the rat.
Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Dexamethasone; Female; Glucocorticoids | 2010 |
Amphetamine treatment during early postnatal development transiently restricts somatic growth.
Topics: Amphetamine; Animals; Brain; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Fe | 2010 |
Prenatal restraint stress: an in vivo microdialysis study on catecholamine release in the rat prefrontal cortex.
Topics: Age Factors; Amphetamine; Animals; Catecholamines; Central Nervous System Stimulants; Dopamine; Extr | 2010 |
Long-term physiological and behavioral effects of exposure to a highly palatable diet during the perinatal and post-weaning periods.
Topics: Adiposity; Age Factors; Amphetamine; Animal Nutritional Physiological Phenomena; Animals; Appetite R | 2010 |
Maternal high-fat intake alters presynaptic regulation of dopamine in the nucleus accumbens and increases motivation for fat rewards in the offspring.
Topics: Amphetamine; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Conditioning, Operant; | 2011 |
The effects of cocaine and amphetamine use during pregnancy on the newborn: myth versus reality.
Topics: Abnormalities, Drug-Induced; Amphetamine; Cocaine; Female; Humans; Infant, Newborn; Maternal Behavio | 2011 |
Individual differences in maternal response to immune challenge predict offspring behavior: contribution of environmental factors.
Topics: Age Factors; Amphetamine; Analysis of Variance; Animals; Animals, Newborn; Antiviral Agents; Behavio | 2011 |
Divergent activation of ventromedial and ventrolateral dopamine systems in animal models of amphetamine sensitization and schizophrenia.
Topics: Action Potentials; Amphetamine; Animals; Central Nervous System Stimulants; Corpus Striatum; Disease | 2012 |
Effects of risperidone and paliperidone pre-treatment on locomotor response following prenatal immune activation.
Topics: Amphetamine; Animals; Animals, Newborn; Antipsychotic Agents; Central Nervous System Stimulants; Dis | 2011 |
Mild prenatal stress-modulated behavior and neuronal spine density without affecting amphetamine sensitization.
Topics: Amphetamine; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Dendritic Spines; Disease Mod | 2011 |
Prenatal amphetamine exposure effects on dopaminergic receptors and transporter in postnatal rats.
Topics: Amphetamine; Animals; Autoradiography; Behavior, Animal; Central Nervous System Stimulants; Child; C | 2011 |
Does prenatal methamphetamine exposure affect the drug-seeking behavior of adult male rats?
Topics: Amphetamine; Analysis of Variance; Animals; Body Weight; Cocaine; Conditioning, Operant; Disease Mod | 2011 |
Abnormal trajectories of neurodevelopment and behavior following in utero insult in the rat.
Topics: Aging; Amphetamine; Animals; Behavior, Animal; Central Nervous System; Corpus Striatum; Data Interpr | 2011 |
Effects of prenatal immune activation and peri-adolescent stress on amphetamine-induced conditioned place preference in the rat.
Topics: Amphetamine; Animals; Conditioning, Classical; Female; Male; Maze Learning; Poly I-C; Pregnancy; Pre | 2012 |
Fluoxetine and aripiprazole treatment following prenatal immune activation exert longstanding effects on rat locomotor response.
Topics: Acute-Phase Reaction; Amphetamine; Animals; Antipsychotic Agents; Aripiprazole; Disease Models, Anim | 2012 |
Prenatal immune challenge in rats: altered responses to dopaminergic and glutamatergic agents, prepulse inhibition of acoustic startle, and reduced route-based learning as a function of maternal body weight gain after prenatal exposure to poly IC.
Topics: Amphetamine; Animals; Dizocilpine Maleate; Dopamine Agents; Excitatory Amino Acid Antagonists; Femal | 2012 |
Maternal immune activation in late gestation enhances locomotor response to acute but not chronic amphetamine treatment in male mice offspring: role of the D1 receptor.
Topics: Amphetamine; Analysis of Variance; Animals; Central Nervous System Stimulants; Corpus Striatum; Dopa | 2012 |
Effects of perinatal exposure to palatable diets on body weight and sensitivity to drugs of abuse in rats.
Topics: Alcohol Drinking; Amphetamine; Animals; Body Weight; Dietary Fats; Eating; Female; Food Preferences; | 2012 |
Do prenatally methamphetamine-exposed adult male rats display general predisposition to drug abuse in the conditioned place preference test?
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Psychologic | 2012 |
Behavioral and antinociceptive effects of different psychostimulant drugs in prenatally methamphetamine-exposed rats.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Female; Male; Me | 2012 |
Hippocampal deep brain stimulation reverses physiological and behavioural deficits in a rodent model of schizophrenia.
Topics: Action Potentials; Amphetamine; Animals; Animals, Newborn; Attention Deficit Disorder with Hyperacti | 2013 |
Variable maternal stress in rats alters locomotor activity, social behavior, and recognition memory in the adult offspring.
Topics: Adrenergic Uptake Inhibitors; Amphetamine; Animals; Antipsychotic Agents; Atomoxetine Hydrochloride; | 2013 |
Immune activation during pregnancy in rats leads to a postpubertal emergence of disrupted latent inhibition, dopaminergic hyperfunction, and altered limbic morphology in the offspring: a novel neurodevelopmental model of schizophrenia.
Topics: Aging; Amphetamine; Animals; Central Nervous System Stimulants; Clozapine; Corpus Striatum; Disease | 2003 |
Repeated i.v. cocaine exposure produces long-lasting behavioral sensitization in pregnant adults, but behavioral tolerance in their offspring.
Topics: Amphetamine; Animals; Animals, Newborn; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dopami | 2003 |
Anoxia at birth induced hyperresponsiveness to amphetamine and stress in postpubertal rats.
Topics: Amphetamine; Animals; Animals, Newborn; Brain; Cesarean Section; Dopamine; Dopamine Agents; Dose-Res | 2003 |
Methylphenidate restores ventral tegmental area dopamine neuron activity in prenatal ethanol-exposed rats by augmenting dopamine neurotransmission.
Topics: Amphetamine; Animals; Dopamine; Dopamine Agents; Dopamine Uptake Inhibitors; Drug Interactions; Elec | 2004 |
Very mild stress of pregnant rats reduces volume and cell number in nucleus accumbens of adult offspring: some parallels to schizophrenia.
Topics: Amphetamine; Analysis of Variance; Animals; Cell Count; Central Nervous System Stimulants; Disease M | 2004 |
Progressive ratio performance following challenge with antipsychotics, amphetamine, or NMDA antagonists in adult rats treated perinatally with phencyclidine.
Topics: Amphetamine; Animals; Animals, Newborn; Antipsychotic Agents; Dose-Response Relationship, Drug; Exci | 2004 |
Prenatal exposure of Long-Evans rats to 17alpha-ethinylestradiol modifies neither latent inhibition nor prepulse inhibition of the startle reflex but elicits minor deficits in exploratory behavior.
Topics: Amphetamine; Animals; Animals, Newborn; Avoidance Learning; Behavior, Animal; Brain; Conditioning, P | 2004 |
Prenatal exposure to a repeated variable stress paradigm elicits behavioral and neuroendocrinological changes in the adult offspring: potential relevance to schizophrenia.
Topics: Age Factors; Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Central Nervous System St | 2005 |
A neurobehavioral systems analysis of adult rats exposed to methylazoxymethanol acetate on E17: implications for the neuropathology of schizophrenia.
Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Brain; Central Nervous System Stimulan | 2006 |
Prenatal and early postnatal dietary sodium restriction sensitizes the adult rat to amphetamines.
Topics: Age Factors; Amphetamine; Animals; Animals, Newborn; Behavior, Animal; Blood Pressure; Central Nervo | 2006 |
Maternal lead exposure produces long-term enhancement of dopaminergic reactivity in rat offspring.
Topics: Amphetamine; Animals; Biogenic Amines; Central Nervous System Stimulants; Cerebral Cortex; Chromatog | 2007 |
Effect of prenatal lead exposure on nigrostriatal neurotransmission and hydroxyl radical formation in rat neostriatum: dopaminergic-nitrergic interaction.
Topics: Amphetamine; Animals; Dopamine; Dopamine Agents; Enzyme Inhibitors; Female; Hydroxyl Radical; Indazo | 2008 |
Prenatal amphetamine reduces alpha but not beta adrenergic receptor binding in brain of adult rats.
Topics: Amphetamine; Animals; Brain; Female; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, | 1983 |
Prenatal corticosterone increases spontaneous and d-amphetamine induced locomotor activity and brain dopamine metabolism in prepubertal male and female rats.
Topics: Aging; Amphetamine; Animals; Behavior, Animal; Corticosterone; Dopamine; Female; Fetus; Locomotion; | 1995 |
Prenatal stress in rats facilitates amphetamine-induced sensitization and induces long-lasting changes in dopamine receptors in the nucleus accumbens.
Topics: Amphetamine; Animals; Autoradiography; Female; Nucleus Accumbens; Pregnancy; Prenatal Exposure Delay | 1995 |
Holoprosencephaly and trisomy 13 in a fetus with maternal early gestational amphetamine abuse--a case report.
Topics: Abnormalities, Drug-Induced; Adolescent; Amphetamine; Chromosomes, Human, Pair 13; Female; Holoprose | 1993 |
Neurobehavioral development of CD-1 mice after combined gestational and postnatal exposure to ozone.
Topics: Amphetamine; Animals; Animals, Newborn; Avoidance Learning; Behavior, Animal; Body Weight; Condition | 1995 |
Prenatal exposure to cocaine selectively disrupts motor responding to D-amphetamine in young and mature rabbits.
Topics: Age Factors; Amphetamine; Animals; Cocaine; Dose-Response Relationship, Drug; Eating; Female; Motor | 1996 |
Effects of prenatal exposure to amphetamine in the medial prefrontal cortex of the rat.
Topics: Amphetamine; Animals; Body Weight; Brain Chemistry; Central Nervous System Stimulants; Dopamine; Fem | 1996 |
Differential effects of prenatal exposure to cocaine and amphetamine on growth parameters and morphometry of the prefrontal cortex in the rat.
Topics: Amphetamine; Animals; Body Weight; Cocaine; Female; Litter Size; Male; Neurons; Organ Size; Prefront | 1996 |
Amphetamine-induced preprodynorphin mRNA expression and kappa-opioid receptor binding in basal ganglia of adult rats after prenatal exposure to diazepam.
Topics: Age Factors; Amphetamine; Analgesics; Animals; Basal Ganglia; Benzeneacetamides; Binding, Competitiv | 1997 |
Influence of chronic prenatal and postnatal administration of naltrexone in locomotor activity induced by morphine in mice.
Topics: Amphetamine; Animals; Animals, Newborn; Animals, Suckling; Dose-Response Relationship, Drug; Drug Re | 1997 |
Stimulant-mediated c-fos induction in striatum as a function of age, sex, and prenatal cocaine exposure.
Topics: Aging; Amphetamine; Animals; Benzazepines; Cocaine; Corpus Striatum; Dopamine Antagonists; Dopamine | 1998 |
Effects of prenatal exposure to low concentrations of carbon monoxide on sexual behaviour and mesolimbic dopaminergic function in rat offspring.
Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Carbon Monoxide; Carboxyhemoglobin; Do | 1998 |
Effects of prenatal cocaine exposure on amphetamine-induced dopamine release in the caudate nucleus of the adult rabbit.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Caudate Nucleus; Cocaine; Dopamine; Dopamine U | 1999 |
Prenatal cocaine exposure alters behavioral and neurochemical sensitization to amphetamine in adult rats.
Topics: Acetylcholine; Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; C | 2000 |
Amphetamine normalizes the electrical activity of dopamine neurons in the ventral tegmental area following prenatal ethanol exposure.
Topics: Action Potentials; Amphetamine; Animals; Cell Count; Central Nervous System Depressants; Dopamine; D | 2001 |
Neurofunctional effects of developmental alcohol exposure in alcohol-preferring and alcohol-nonpreferring rats.
Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Amphetamine; Animals; Avoidance Learning; Bra | 2001 |
Increased sensitivity in dopamine D(2)-like brain receptors from 2,4-dichlorophenoxyacetic acid (2,4-D)-exposed and amphetamine-challenged rats.
Topics: 2,4-Dichlorophenoxyacetic Acid; Aging; Amphetamine; Animals; Benzamides; Brain; Dopamine Antagonists | 2002 |
Eight-arm maze performance, neophobia, and hippocampal cholinergic alterations after prenatal oxazepam in mice.
Topics: Amphetamine; Animals; Anxiety; Behavior, Animal; Dose-Response Relationship, Drug; Exploratory Behav | 1992 |
Physical and behavioral development in rats after late prenatal exposure to diazepam.
Topics: Amphetamine; Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Body Temperature; Body | 1990 |
Neurochemical effects of prenatal haloperidol exposure.
Topics: Amphetamine; Animals; Body Weight; Brain Chemistry; Female; Haloperidol; Male; Pregnancy; Pregnancy | 1989 |
Alterations in behavioral and striatal dopamine asymmetries induced by prenatal stress.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Behavior, Animal; Body Weight; Caudate Nucleus | 1989 |
Predictive indicators for adjustment in 4-year-old children whose mothers used amphetamine during pregnancy.
Topics: Amphetamine; Child Behavior Disorders; Child Development; Child, Preschool; Female; Follow-Up Studie | 1988 |
Reactivity to amphetamine in perinatally undernourished rats: behavioral and neurochemical correlates.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Amphetamine; Animals; Behavior, Animal; Brain | 1986 |
The effects of prenatal morphine on the responsiveness to morphine and amphetamine.
Topics: Amphetamine; Animals; Biogenic Amines; Conditioning, Operant; Drug Tolerance; Female; Morphine; Preg | 1986 |
Prenatal benzodiazepine effects in mice: postnatal behavioral development, response to drug challenges, and adult discrimination learning.
Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Benzodiazepines; Discrimination Learning | 1986 |
Stress in early ontogenesis and reactivity of hypothalamo-pituitary-adrenal system in adult rats.
Topics: Adrenalectomy; Amphetamine; Animals; Cold Temperature; Corticosterone; Female; Hydrocortisone; Hypot | 1985 |
Short-, medium-, and long-term effects of prenatal oxazepam on neurobehavioural development of mice.
Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Female; Growth Disorders; Learning Disab | 1985 |