Page last updated: 2024-10-25

amphetamine and Deficiency, Mental

amphetamine has been researched along with Deficiency, Mental in 20 studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Research Excerpts

ExcerptRelevanceReference
"Fragile X syndrome is an X-linked form of mental retardation including, among others, symptoms such as stereotypic behaviour, hyperactivity, hyperarousal, and cognitive deficits."1.32Object recognition impairment in Fmr1 knockout mice is reversed by amphetamine: involvement of dopamine in the medial prefrontal cortex. ( Catania, MV; Musumeci, SA; Pascucci, T; Puglisi-Allegra, S; Ventura, R, 2004)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199016 (80.00)18.7374
1990's1 (5.00)18.2507
2000's2 (10.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Giovanoli, S1
Werge, TM1
Mortensen, PB1
Didriksen, M1
Meyer, U1
NOURRISSIER, MT1
GRISLAIN, JR1
FISH, CH1
BOWLING, E1
MCCONNELL, TR1
CROMWELL, RL1
MORRIS, JV1
MACGILLIVRAY, RC1
MATHIESON, CM1
REBHUN, J1
Ventura, R1
Pascucci, T1
Catania, MV1
Musumeci, SA1
Puglisi-Allegra, S1
Jou, R1
Handen, B1
Hardan, A1
Kinsbourne, M1
Schaller, JL1
Behar, D1
Gadow, KD1
Sulestrowska, H1
Omenn, GS1
Alexandris, A1
Lundell, FW1
Kuhn, R1
Taeschler, M1
Schoch, J1
Claghorn, J1
Neblett, C1
Sutter, E1
Farrell, G1
Kraft, I1
Kupernik, K1
Lobb, H1
Berkson, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Development and Validation of a System for the Anticipation of Challenging Behaviors of People With Autism Spectrum Disorder Based on a Smart Shirt: a Mixed-method Design[NCT05340608]51 participants (Actual)Observational2022-06-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for amphetamine and Deficiency, Mental

ArticleYear
Prevalence and efficacy of stimulant drug use with mentally retarded children and youth.
    Psychopharmacology bulletin, 1985, Volume: 21, Issue:2

    Topics: Adolescent; Adult; Aged; Amphetamine; Attention Deficit Disorder with Hyperactivity; Central Nervous

1985
Genetic approaches to the syndrome of minimal brain dysfunction.
    Annals of the New York Academy of Sciences, 1973, Feb-28, Volume: 205

    Topics: Amphetamine; Attention Deficit Disorder with Hyperactivity; Child; Dextroamphetamine; Diseases in Tw

1973

Trials

3 trials available for amphetamine and Deficiency, Mental

ArticleYear
Effect of thioridazine, amphetamine and placebo on the hyperkinetic syndrome and cognitive area in mentally deficient children.
    Canadian Medical Association journal, 1968, Jan-13, Volume: 98, Issue:2

    Topics: Aggression; Amphetamine; Attention; Child; Child Behavior Disorders; Clinical Trials as Topic; Human

1968
[Pharmacologic and clinical properties of a new butyrophenone derivative (FR 33)].
    Psychopharmacologia, 1966, Volume: 9, Issue:4

    Topics: Adult; Amphetamine; Animals; Antidepressive Agents; Butyrophenones; Catalepsy; Catatonia; Clinical T

1966
The effect of drugs on hyperactivity in children with some observations of changes in mineral metabolism.
    The Journal of nervous and mental disease, 1971, Volume: 153, Issue:2

    Topics: Acetazolamide; Adolescent; Amphetamine; Analysis of Variance; Child; Child, Preschool; Chlorides; Cl

1971

Other Studies

15 other studies available for amphetamine and Deficiency, Mental

ArticleYear
Interactive effects between hemizygous 15q13.3 microdeletion and peripubertal stress on adult behavioral functions.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019, Volume: 44, Issue:4

    Topics: Age Factors; Amphetamine; Anhedonia; Animals; Anxiety; Behavior, Animal; Central Nervous System Stim

2019
[Mental deficiencies].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1953, Sep-18, Volume: 29, Issue:56

    Topics: Amphetamine; Amphetamines; Diet, Reducing; Glutamates; Intellectual Disability

1953
[Modern stimulants of intelligence in pediatrics].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1954, Jan-20, Volume: 30, Issue:5

    Topics: Amphetamine; Amphetamines; Central Nervous System Agents; Central Nervous System Stimulants; Glutama

1954
Effect of amphetamines on speech defects in the mentally retarded.
    California medicine, 1962, Volume: 96

    Topics: Amphetamine; Aphasia; Cleft Palate; Deafness; Dextroamphetamine; Double-Blind Method; Humans; Intell

1962
STUDIES IN ACTIVITY LEVEL. VII. EFFECTS OF AMPHETAMINE DRUG ADMINISTRATION ON THE ACTIVITY LEVEL OF RETARDED CHILDREN.
    American journal of mental deficiency, 1964, Volume: 68

    Topics: Adolescent; Amphetamine; Amphetamines; Child; Humans; Intellectual Disability; Movement Disorders; P

1964
The results of the experimental administration of amphetamine sulphate in oligophrenia.
    The Journal of mental science, 1955, Volume: 101, Issue:422

    Topics: Amphetamine; Amphetamines; Diet, Reducing; Intellectual Disability

1955
Clinical observations on iproniazid in idiots with epilepsy.
    California medicine, 1960, Volume: 92

    Topics: Amines; Amphetamine; Animals; Ephedrine; Epilepsy; Guinea Pigs; Intellectual Disability; Iproniazid;

1960
Object recognition impairment in Fmr1 knockout mice is reversed by amphetamine: involvement of dopamine in the medial prefrontal cortex.
    Behavioural pharmacology, 2004, Volume: 15, Issue:5-6

    Topics: Amphetamine; Animals; Central Nervous System Stimulants; Cognition Disorders; Discrimination Learnin

2004
Psychostimulant treatment of adults with mental retardation and attention-deficit hyperactivity disorder.
    Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists, 2004, Volume: 12, Issue:4

    Topics: Adult; Amphetamine; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants

2004
Do repetitive movement patterns in children and animals serve a dearousing function?
    Journal of developmental and behavioral pediatrics : JDBP, 1980, Volume: 1, Issue:1

    Topics: Amphetamine; Animals; Arousal; Autistic Disorder; Displacement, Psychological; Humans; Intellectual

1980
Selegiline for the delivery of small doses of amphetamine.
    The Journal of neuropsychiatry and clinical neurosciences, 1997,Spring, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Amphetamine; Attention Deficit Disorder with Hyperactivity; Child; Child Developm

1997
[Treatment of psychopathologic sequelae of early childhood brain damage].
    Psychiatrie, Neurologie und medizinische Psychologie. Beihefte, 1968, Volume: 8-9

    Topics: Amphetamine; Antipsychotic Agents; Brain Damage, Chronic; Child; Drug Therapy, Combination; Glutamat

1968
[Limits of biological therapy in child psychiatry].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1966, Volume: 66, Issue:7

    Topics: Adolescent; Amphetamine; Barbiturates; Child; Child, Preschool; Enuresis; Fear; Feeding and Eating D

1966
Trace GSR conditioning with benzedrine in mentally defective and normal adults.
    American journal of mental deficiency, 1968, Volume: 73, Issue:2

    Topics: Adaptation, Physiological; Adolescent; Adult; Amphetamine; Analysis of Variance; Conditioning, Class

1968
Stereotyped movements of mental defectives: VI. No effect of amphetamine or a barbiturate.
    Perceptual and motor skills, 1965, Volume: 21, Issue:3

    Topics: Adult; Amphetamine; Blindness; Humans; Intellectual Disability; Male; Movement; Psychopharmacology;

1965