Page last updated: 2024-10-25

amphetamine and Complications, Pregnancy

amphetamine has been researched along with Complications, Pregnancy in 38 studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Research Excerpts

ExcerptRelevanceReference
"This case report describes a woman with narcolepsy treated with racemic amphetamine (rac-amphetamine) during pregnancy and breastfeeding with follow-up on the infant's development up to 10 months of age."7.81Narcolepsy Treated with Racemic Amphetamine during Pregnancy and Breastfeeding. ( Beck, O; Öhman, I; Sarman, I; Wikner, BN, 2015)
" This case study reflects on the maternity care provided for a woman who continued to use amphetamines during her pregnancy; and who was diagnosed with placenta praevia and subsequently suffered a placental abruption."7.79Placenta praevia, placental abruption and amphetamine use in pregnancy: a case study. ( Geraghty, S; McLaurin, R, 2013)
"In a tertiary neonatal care center in Taiwan, three neonates whose mothers self-reported heroin abuse with methadone treatment during pregnancy were studied."7.78Perinatal effects of combined use of heroin, methadone, and amphetamine during pregnancy and quantitative measurement of metabolites in hair. ( Chang, YZ; Chen, JY; Chen, SC; Ng, YY; Su, PH; Yang, C, 2012)
"From 1998 to 2004, the hospitalization ratio for cocaine abuse decreased 44%, whereas the hospitalization ratio for amphetamine abuse doubled."7.74Hospitalizations with amphetamine abuse among pregnant women. ( Cox, S; Jamieson, DJ; Kourtis, AP; Posner, SF, 2008)
"Sixty-five children born to women who all used amphetamine during pregnancy have been followed prospectively since birth 1976-77."7.69Amphetamine addiction during pregnancy: 10-year follow-up. ( Eriksson, M; Zetterström, R, 1994)
"Sixty-five children whose mothers were addicted to amphetamine during pregnancy were followed prospectively until eight years of age, when they were tested in their homes."7.67Health and development of 8-year-old children whose mothers abused amphetamine during pregnancy. ( Billing, L; Eriksson, M; Steneroth, G; Zetterström, R, 1989)
"A group of 69 amphetamine-addicted women who all abused during part of or the whole pregnancy have been followed since the birth of the index child born in 1976 or 1977."7.67Influence of pregnancy and child-rearing on amphetamine-addicted women. Five-year follow-up after delivery. ( Eriksson, M; Steneroth, G; Zetterström, R, 1986)
"The adverse effects of amphetamine addiction during pregnancy and the neonatal period were studied in 69 Swedish women."7.66Amphetamine addiction and pregnancy. II. Pregnancy, delivery and the neonatal period. Socio-medical aspects. ( Eriksson, M; Larsson, G; Zetterström, R, 1981)
"In Group 2, psychiatric illness and drug abuse were more common among parents and siblings than in Group 1."5.26Amphetamine addiction and pregnancy. Psycho-social and medical aspects. ( Eriksson, M; Larsson, G; Zetterström, R, 1979)
" Women who received amphetamine-dextroamphetamine or methylphenidate monotherapy in the first half of pregnancy were compared with unexposed women."3.85Placental Complications Associated With Psychostimulant Use in Pregnancy. ( Bateman, BT; Cohen, JM; Desai, RJ; Gray, KJ; Hernández-Díaz, S; Huybrechts, KF; Mogun, H; Park, Y; Patorno, E, 2017)
"This case report describes a woman with narcolepsy treated with racemic amphetamine (rac-amphetamine) during pregnancy and breastfeeding with follow-up on the infant's development up to 10 months of age."3.81Narcolepsy Treated with Racemic Amphetamine during Pregnancy and Breastfeeding. ( Beck, O; Öhman, I; Sarman, I; Wikner, BN, 2015)
" This case study reflects on the maternity care provided for a woman who continued to use amphetamines during her pregnancy; and who was diagnosed with placenta praevia and subsequently suffered a placental abruption."3.79Placenta praevia, placental abruption and amphetamine use in pregnancy: a case study. ( Geraghty, S; McLaurin, R, 2013)
"In a tertiary neonatal care center in Taiwan, three neonates whose mothers self-reported heroin abuse with methadone treatment during pregnancy were studied."3.78Perinatal effects of combined use of heroin, methadone, and amphetamine during pregnancy and quantitative measurement of metabolites in hair. ( Chang, YZ; Chen, JY; Chen, SC; Ng, YY; Su, PH; Yang, C, 2012)
"From 1998 to 2004, the hospitalization ratio for cocaine abuse decreased 44%, whereas the hospitalization ratio for amphetamine abuse doubled."3.74Hospitalizations with amphetamine abuse among pregnant women. ( Cox, S; Jamieson, DJ; Kourtis, AP; Posner, SF, 2008)
"Sixty-five children born to women who all used amphetamine during pregnancy have been followed prospectively since birth 1976-77."3.69Amphetamine addiction during pregnancy: 10-year follow-up. ( Eriksson, M; Zetterström, R, 1994)
" In this report, we show that prenatal stress (restraint of the mother during the last week of pregnancy) may contribute to an individual's vulnerability to develop amphetamine self-administration."3.68Increased locomotor response to novelty and propensity to intravenous amphetamine self-administration in adult offspring of stressed mothers. ( Abrous, N; Deminière, JM; Guegan, G; Le Moal, M; Maccari, S; Piazza, PV; Simon, H, 1992)
"Sixty-five children whose mothers were addicted to amphetamine during pregnancy were followed prospectively until eight years of age, when they were tested in their homes."3.67Health and development of 8-year-old children whose mothers abused amphetamine during pregnancy. ( Billing, L; Eriksson, M; Steneroth, G; Zetterström, R, 1989)
"A group of 69 amphetamine-addicted women who all abused during part of or the whole pregnancy have been followed since the birth of the index child born in 1976 or 1977."3.67Influence of pregnancy and child-rearing on amphetamine-addicted women. Five-year follow-up after delivery. ( Eriksson, M; Steneroth, G; Zetterström, R, 1986)
"Various stressors (laparotomy, cold or amphetamine injection) applied during the last third of pregnancy resulted in an increase of corticosterone level in mothers and a decrease of the response to emotional stressor (restriction) in their adult offspring."3.67Stress in early ontogenesis and reactivity of hypothalamo-pituitary-adrenal system in adult rats. ( Maslova, LN; Naumenko, EV, 1985)
"The adverse effects of amphetamine addiction during pregnancy and the neonatal period were studied in 69 Swedish women."3.66Amphetamine addiction and pregnancy. II. Pregnancy, delivery and the neonatal period. Socio-medical aspects. ( Eriksson, M; Larsson, G; Zetterström, R, 1981)
"Drug abuse during pregnancy has attracted national attention, but most studies are from large cities."1.29Drug abuse in an obstetric population of a midsized city. ( Hawthorne, JL; Maier, RC, 1993)
"Perinatal substance abuse is independently associated with growth retardation and prematurity."1.28The perinatal impact of cocaine, amphetamine, and opiate use detected by universal intrapartum screening. ( Batra, KK; Evans, AT; Gillogley, KM; Hansen, RL; Samuels, SJ, 1990)
"Amphetamines were detected in 13% (n = 65) of patients."1.28Prevalence of use of cocaine and other substances in an obstetric population. ( Fink, DJ; Fox, HE; Matera, C; Moomjy, M; Warren, WB, 1990)
"In Group 2, psychiatric illness and drug abuse were more common among parents and siblings than in Group 1."1.26Amphetamine addiction and pregnancy. Psycho-social and medical aspects. ( Eriksson, M; Larsson, G; Zetterström, R, 1979)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199022 (57.89)18.7374
1990's8 (21.05)18.2507
2000's2 (5.26)29.6817
2010's6 (15.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cohen, JM1
Hernández-Díaz, S2
Bateman, BT2
Park, Y1
Desai, RJ1
Gray, KJ1
Patorno, E1
Mogun, H2
Huybrechts, KF2
Bröms, G1
Christensen, LB1
Einarsdóttir, K1
Engeland, A1
Furu, K1
Gissler, M1
Karlsson, P1
Karlstad, Ø1
Kieler, H1
Lahesmaa-Korpinen, AM1
Nørgaard, M1
Reutfors, J1
Sørensen, HT1
Zoega, H1
Öhman, I1
Wikner, BN1
Beck, O1
Sarman, I1
Thompson, BL1
Levitt, P1
Stanwood, GD1
Byrnes, JJ1
Bridges, RS1
Byrnes, EM1
Su, PH1
Chang, YZ1
Yang, C1
Ng, YY1
Chen, JY1
Chen, SC1
McLaurin, R1
Geraghty, S1
CALDWELL, W1
KING, AG1
CHAPMAN, JD1
BAYLY, MA1
CRAIG, PE1
ANSPAUGH, RD1
VIGLIONE, JP1
BRESLOW, S1
BELAFSKY, HA1
SHANGOLD, JE1
HIRSCH, LM1
STAHL, MB1
Cox, S1
Posner, SF1
Kourtis, AP1
Jamieson, DJ1
Langer, DH1
Brown, GL1
Docherty, JP1
Billing, L2
Eriksson, M6
Larsson, G3
Zetterström, R6
Franssen, RM1
Stolk, LM1
van den Brand, W1
Smit, BJ1
Hawthorne, JL1
Maier, RC1
Gurnack, AM1
Paul, W1
Halmesmäki, E1
Kari, A1
Deminière, JM1
Piazza, PV1
Guegan, G1
Abrous, N1
Maccari, S1
Le Moal, M1
Simon, H1
Gillogley, KM1
Evans, AT1
Hansen, RL1
Samuels, SJ1
Batra, KK1
Matera, C1
Warren, WB1
Moomjy, M1
Fink, DJ1
Fox, HE1
Steneroth, G2
Naumenko, EV1
Maslova, LN1
Beck, KJ2
Zumbé, FJ2
Schönhöfer, PS2
Waldmann, H1
Ramer, CM1
Kornetsky, C1
Kupernik, K1
Neuberg, R1

Reviews

4 reviews available for amphetamine and Complications, Pregnancy

ArticleYear
Prenatal exposure to drugs: effects on brain development and implications for policy and education.
    Nature reviews. Neuroscience, 2009, Volume: 10, Issue:4

    Topics: Alcohols; Amphetamine; Antidepressive Agents; Brain; Child; Crack Cocaine; Drug-Related Side Effects

2009
Dopamine receptor supersensitivity and schizophrenia: a review.
    Schizophrenia bulletin, 1981, Volume: 7, Issue:2

    Topics: Adenylyl Cyclases; Amphetamine; Animals; Apomorphine; Brain Chemistry; Dopamine; Female; Guinea Pigs

1981
[Drugs and pregnancy].
    Duodecim; laaketieteellinen aikakauskirja, 1998, Volume: 114, Issue:20

    Topics: Amphetamine; Cannabis; Cocaine; Female; Fetus; Hallucinogens; Humans; Illicit Drugs; Narcotics; Preg

1998
Psychoactive drugs in the immature organism.
    Psychopharmacologia, 1970, Volume: 17, Issue:2

    Topics: Amphetamine; Animals; Autistic Disorder; Behavior, Animal; Catecholamines; Child; Child Behavior; Ch

1970

Trials

1 trial available for amphetamine and Complications, Pregnancy

ArticleYear
Psychoactive drugs in the immature organism.
    Psychopharmacologia, 1970, Volume: 17, Issue:2

    Topics: Amphetamine; Animals; Autistic Disorder; Behavior, Animal; Catecholamines; Child; Child Behavior; Ch

1970

Other Studies

34 other studies available for amphetamine and Complications, Pregnancy

ArticleYear
Placental Complications Associated With Psychostimulant Use in Pregnancy.
    Obstetrics and gynecology, 2017, Volume: 130, Issue:6

    Topics: Abruptio Placentae; Adrenergic Uptake Inhibitors; Adult; Amphetamine; Atomoxetine Hydrochloride; Att

2017
Association Between Methylphenidate and Amphetamine Use in Pregnancy and Risk of Congenital Malformations: A Cohort Study From the International Pregnancy Safety Study Consortium.
    JAMA psychiatry, 2018, 02-01, Volume: 75, Issue:2

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Amphetamine; Attention Deficit Disorder with Hyperac

2018
Narcolepsy Treated with Racemic Amphetamine during Pregnancy and Breastfeeding.
    Journal of human lactation : official journal of International Lactation Consultant Association, 2015, Volume: 31, Issue:3

    Topics: Adult; Amphetamine; Breast Feeding; Central Nervous System Stimulants; Child Development; Female; Hu

2015
Amphetamine sensitization in reproductively experienced female rats.
    Neuroscience letters, 2011, Sep-20, Volume: 502, Issue:3

    Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Dopamine Uptake Inhibitors; Dose-Response Relat

2011
Perinatal effects of combined use of heroin, methadone, and amphetamine during pregnancy and quantitative measurement of metabolites in hair.
    Pediatrics and neonatology, 2012, Volume: 53, Issue:2

    Topics: Adult; Amphetamine; Electroencephalography; Female; Fetus; Gas Chromatography-Mass Spectrometry; Hai

2012
Placenta praevia, placental abruption and amphetamine use in pregnancy: a case study.
    Women and birth : journal of the Australian College of Midwives, 2013, Volume: 26, Issue:2

    Topics: Abruptio Placentae; Amphetamine; Central Nervous System Stimulants; Cesarean Section; Female; Fetal

2013
d-Amphetamine sulfate in the treatment of prepartum nausea and vomiting: a two-year study of 150 unwed mothers.
    American journal of obstetrics and gynecology, 1954, Volume: 68, Issue:4

    Topics: Amphetamine; Amphetamines; Dextroamphetamine; Female; Humans; Mothers; Nausea; Pregnancy; Pregnancy

1954
The treatment of pregnancy nausea with a pill.
    Obstetrics and gynecology, 1955, Volume: 6, Issue:3

    Topics: Amphetamine; Amphetamines; Anti-Allergic Agents; Female; Histamine H1 Antagonists; Humans; Nausea; P

1955
Control of weight gain in pregnancy, utilizing methamphetamine.
    The Journal of the American Osteopathic Association, 1961, Volume: 60

    Topics: Amphetamine; Amphetamines; Female; Humans; Methamphetamine; Obesity; Pregnancy; Pregnancy Complicati

1961
Desoxyephedrine as an aid in weight control for pregnant clinic patients.
    Quarterly bulletin. Northwestern University (Evanston, Ill.). Medical School, 1960, Volume: 34

    Topics: Amphetamine; Amphetamines; Female; Humans; Methamphetamine; Obesity; Pregnancy; Pregnancy Complicati

1960
Use of an anorexic antidepressant in the control of nausea and vomiting of pregnancy.
    The Journal of the Oklahoma State Medical Association, 1955, Volume: 48, Issue:2

    Topics: Amphetamine; Amphetamines; Antidepressive Agents; Barbiturates; Nausea; Pregnancy; Pregnancy Complic

1955
Effects of dexedrine sulfate on nausea and vomiting of pregnancy.
    American journal of obstetrics and gynecology, 1950, Volume: 60, Issue:4

    Topics: Amphetamine; Amphetamines; Dextroamphetamine; Female; Humans; Nausea; Pregnancy; Pregnancy Complicat

1950
Appetite control in pregnancy using combined prochlorperazine-dextroamphetamine.
    Clinical medicine (Northfield, Ill.), 1962, Volume: 69

    Topics: Amphetamine; Amphetamines; Appetite; Appetite Regulation; Dextroamphetamine; Female; Obesity; Pregna

1962
Control of weight gain in pregnancy: double blind study of a dieting aid.
    Clinical medicine (Northfield, Ill.), 1963, Volume: 70

    Topics: Amphetamine; Amphetamines; Diet, Reducing; Double-Blind Method; Female; Humans; Meprobamate; Pregnan

1963
Hospitalizations with amphetamine abuse among pregnant women.
    Obstetrics and gynecology, 2008, Volume: 111, Issue:2 Pt 1

    Topics: Adolescent; Adult; Age Factors; Amphetamine; Amphetamine-Related Disorders; Chi-Square Distribution;

2008
Amphetamine addiction and pregnancy. III. One year follow-up of the children. Psychosocial and pediatric aspects.
    Acta paediatrica Scandinavica, 1980, Volume: 69, Issue:5

    Topics: Amphetamine; Child Development; Family; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn;

1980
Amphetamine addiction and pregnancy. II. Pregnancy, delivery and the neonatal period. Socio-medical aspects.
    Acta obstetricia et gynecologica Scandinavica, 1981, Volume: 60, Issue:3

    Topics: Abnormalities, Drug-Induced; Amphetamine; Female; Fetal Death; Humans; Infant Mortality; Infant, New

1981
Amphetamine addiction during pregnancy: 10-year follow-up.
    Acta paediatrica (Oslo, Norway : 1992). Supplement, 1994, Volume: 404

    Topics: Amphetamine; Child; Child Behavior; Child of Impaired Parents; Child, Preschool; Developmental Disab

1994
Analysis of morphine and amphetamine in meconium with immunoassay and HPLC-diode-array detection.
    Journal of analytical toxicology, 1994, Volume: 18, Issue:5

    Topics: Amphetamine; Chromatography, High Pressure Liquid; Female; Fluorescence Polarization Immunoassay; Hu

1994
Drug abuse in an obstetric population of a midsized city.
    Southern medical journal, 1993, Volume: 86, Issue:12

    Topics: Adult; Amphetamine; Barbiturates; Benzodiazepines; Cannabis; Cocaine; Female; Georgia; Humans; Illic

1993
Factors related to perinatal substance abuse in a California county.
    Perceptual and motor skills, 1997, Volume: 84, Issue:3 Pt 2

    Topics: Adolescent; Adult; Amphetamine; Barbiturates; California; Dronabinol; Female; Humans; Methamphetamin

1997
Amphetamine addiction and pregnancy. Psycho-social and medical aspects.
    Acta psychiatrica Scandinavica, 1979, Volume: 60, Issue:4

    Topics: Adolescent; Adult; Alcoholism; Amphetamine; Female; Foster Home Care; Humans; Interview, Psychologic

1979
Increased locomotor response to novelty and propensity to intravenous amphetamine self-administration in adult offspring of stressed mothers.
    Brain research, 1992, Jul-17, Volume: 586, Issue:1

    Topics: Amphetamine; Animals; Female; Injections, Intravenous; Motor Activity; Pregnancy; Pregnancy Complica

1992
The perinatal impact of cocaine, amphetamine, and opiate use detected by universal intrapartum screening.
    American journal of obstetrics and gynecology, 1990, Volume: 163, Issue:5 Pt 1

    Topics: Adult; Amphetamine; Analysis of Variance; Birth Weight; Body Height; Chi-Square Distribution; Cocain

1990
Prevalence of use of cocaine and other substances in an obstetric population.
    American journal of obstetrics and gynecology, 1990, Volume: 163, Issue:3

    Topics: Adolescent; Adult; Amphetamine; Cocaine; Female; Humans; New York City; Pregnancy; Pregnancy Complic

1990
Health and development of 8-year-old children whose mothers abused amphetamine during pregnancy.
    Acta paediatrica Scandinavica, 1989, Volume: 78, Issue:6

    Topics: Amphetamine; Child Behavior Disorders; Child Development; Child, Preschool; Female; Growth; Humans;

1989
Influence of pregnancy and child-rearing on amphetamine-addicted women. Five-year follow-up after delivery.
    Acta psychiatrica Scandinavica, 1986, Volume: 73, Issue:6

    Topics: Alcoholism; Amphetamine; Child; Child Rearing; Child Welfare; Child, Preschool; Crime; Female; Follo

1986
Stress in early ontogenesis and reactivity of hypothalamo-pituitary-adrenal system in adult rats.
    Endocrinologia experimentalis, 1985, Volume: 19, Issue:3

    Topics: Adrenalectomy; Amphetamine; Animals; Cold Temperature; Corticosterone; Female; Hydrocortisone; Hypot

1985
[Obstetrical problems in drug abuse].
    Medizinische Klinik, 1974, Volume: 69, Issue:38

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Amphetamine; Dronabinol; Female; Humans; Infant,

1974
[Gynecological-obstetrical problems in female drug users and drug addicts].
    Geburtshilfe und Frauenheilkunde, 1973, Volume: 33, Issue:4

    Topics: Adolescent; Adult; Amenorrhea; Amphetamine; Barbiturates; Dronabinol; Dysmenorrhea; Female; Hallucin

1973
[Psychiatric emergencies during pregnancy and in the puerperium].
    Munchener medizinische Wochenschrift (1950), 1973, Jun-01, Volume: 115, Issue:22

    Topics: Amphetamine; Cannabis; Emergencies; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Lyse

1973
The case history of an infant born to an amphetamine-addicted mother.
    Clinical pediatrics, 1974, Volume: 13, Issue:7

    Topics: Adult; Amphetamine; Apgar Score; Blood Glucose; Electroencephalography; Female; Fetus; Fixation, Ocu

1974
[Limits of biological therapy in child psychiatry].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1966, Volume: 66, Issue:7

    Topics: Adolescent; Amphetamine; Barbiturates; Child; Child, Preschool; Enuresis; Fear; Feeding and Eating D

1966
Drug dependence and pregnancy: a review of the problems and their management.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1970, Volume: 77, Issue:12

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Amphetamine; Barbiturates; Cannabis; Fema

1970