amphetamine has been researched along with Coloboma in 2 studies
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
Coloboma: Congenital anomaly in which some of the structures of the eye are absent due to incomplete fusion of the fetal intraocular fissure during gestation.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here we dissect the components of dopaminergic neurotransmission in the hyperactive mouse mutant coloboma to identify pre- and postsynaptic elements essential for the effects of amphetamine in these mice." | 3.74 | D2-like dopamine receptors mediate the response to amphetamine in a mouse model of ADHD. ( Fan, X; Hess, EJ, 2007) |
| "The mouse mutant coloboma (Cml+) exhibits profound spontaneous locomotor hyperactivity resulting from a deletion mutation." | 1.29 | Mouse model of hyperkinesis implicates SNAP-25 in behavioral regulation. ( Collins, KA; Hess, EJ; Wilson, MC, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fan, X | 1 |
| Hess, EJ | 2 |
| Collins, KA | 1 |
| Wilson, MC | 1 |
2 other studies available for amphetamine and Coloboma
| Article | Year |
|---|---|
D2-like dopamine receptors mediate the response to amphetamine in a mouse model of ADHD.
Topics: Adenylyl Cyclases; Amphetamine; Animals; Attention Deficit Disorder with Hyperactivity; Catalepsy; C | 2007 |
Mouse model of hyperkinesis implicates SNAP-25 in behavioral regulation.
Topics: Amphetamine; Animals; Behavior, Animal; Coloboma; Disease Models, Animal; Dopamine Agonists; Gene Ex | 1996 |