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amphetamine and Cognitive Decline

amphetamine has been researched along with Cognitive Decline in 7 studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Research Excerpts

ExcerptRelevanceReference
"If amphetamine can enhance the therapeutic effects of TCT, this would provide strong support for a "PACT" treatment paradigm for schizophrenia."6.84Amphetamine Enhances Gains in Auditory Discrimination Training in Adult Schizophrenia Patients. ( Alvarez, AI; Bhakta, SG; Hughes, EL; Light, GA; Rana, B; Swerdlow, NR; Talledo, J; Tarasenko, M; Vinogradov, S, 2017)
"If amphetamine can enhance the therapeutic effects of TCT, this would provide strong support for a "PACT" treatment paradigm for schizophrenia."2.84Amphetamine Enhances Gains in Auditory Discrimination Training in Adult Schizophrenia Patients. ( Alvarez, AI; Bhakta, SG; Hughes, EL; Light, GA; Rana, B; Swerdlow, NR; Talledo, J; Tarasenko, M; Vinogradov, S, 2017)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (85.71)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Perez-Palomar, B1
Erdozain, AM1
Erkizia-Santamaría, I1
Ortega, JE1
Meana, JJ1
Pappas, AL1
Bey, AL1
Wang, X1
Rossi, M1
Kim, YH1
Yan, H1
Porkka, F1
Duffney, LJ1
Phillips, SM1
Cao, X1
Ding, JD1
Rodriguiz, RM1
Yin, HH1
Weinberg, RJ1
Ji, RR1
Wetsel, WC1
Jiang, YH1
Grimm, CM1
Aksamaz, S1
Schulz, S1
Teutsch, J1
Sicinski, P1
Liss, B1
Kätzel, D1
Nilsson, SRO1
Heath, CJ1
Takillah, S1
Didienne, S1
Fejgin, K1
Nielsen, V1
Nielsen, J1
Saksida, LM1
Mariani, J1
Faure, P1
Didriksen, M1
Robbins, TW1
Bussey, TJ1
Mar, AC1
Lappin, JM1
Sara, GE1
Managò, F1
Mereu, M1
Mastwal, S1
Mastrogiacomo, R1
Scheggia, D1
Emanuele, M1
De Luca, MA1
Weinberger, DR1
Wang, KH1
Papaleo, F1
Swerdlow, NR1
Tarasenko, M1
Bhakta, SG1
Talledo, J1
Alvarez, AI1
Hughes, EL1
Rana, B1
Vinogradov, S1
Light, GA1

Reviews

1 review available for amphetamine and Cognitive Decline

ArticleYear
Psychostimulant use and the brain.
    Addiction (Abingdon, England), 2019, Volume: 114, Issue:11

    Topics: Amphetamine; Amphetamine-Related Disorders; Brain; Central Nervous System Stimulants; Cocaine; Cocai

2019

Trials

1 trial available for amphetamine and Cognitive Decline

ArticleYear
Amphetamine Enhances Gains in Auditory Discrimination Training in Adult Schizophrenia Patients.
    Schizophrenia bulletin, 2017, 07-01, Volume: 43, Issue:4

    Topics: Adult; Amphetamine; Auditory Perception; Central Nervous System Stimulants; Cognitive Dysfunction; C

2017

Other Studies

5 other studies available for amphetamine and Cognitive Decline

ArticleYear
Maternal Immune Activation Induces Cortical Catecholaminergic Hypofunction and Cognitive Impairments in Offspring.
    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2023, Volume: 18, Issue:3

    Topics: Amphetamine; Animals; Brain; Cognitive Dysfunction; Disease Models, Animal; Dopamine; Female; Humans

2023
Deficiency of Shank2 causes mania-like behavior that responds to mood stabilizers.
    JCI insight, 2017, 10-19, Volume: 2, Issue:20

    Topics: Amphetamine; Anhedonia; Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Central Nervo

2017
Schizophrenia-related cognitive dysfunction in the Cyclin-D2 knockout mouse model of ventral hippocampal hyperactivity.
    Translational psychiatry, 2018, 10-09, Volume: 8, Issue:1

    Topics: Amino Acids; Amphetamine; Animals; Attention; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyc

2018
Continuous performance test impairment in a 22q11.2 microdeletion mouse model: improvement by amphetamine.
    Translational psychiatry, 2018, 11-14, Volume: 8, Issue:1

    Topics: Amphetamine; Animals; Attention; Behavior, Animal; Central Nervous System Stimulants; Cognitive Dysf

2018
Genetic Disruption of Arc/Arg3.1 in Mice Causes Alterations in Dopamine and Neurobehavioral Phenotypes Related to Schizophrenia.
    Cell reports, 2016, 08-23, Volume: 16, Issue:8

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Cognitive Dysfunct

2016