amphetamine has been researched along with Cocaine Abuse in 62 studies
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "From 1998 to 2004, the hospitalization ratio for cocaine abuse decreased 44%, whereas the hospitalization ratio for amphetamine abuse doubled." | 7.74 | Hospitalizations with amphetamine abuse among pregnant women. ( Cox, S; Jamieson, DJ; Kourtis, AP; Posner, SF, 2008) |
| " Relative to vehicle, SHR and WIS with adolescent d-amphetamine treatment self-administered less cocaine upon reaching acquisition criteria, and WIS additionally acquired cocaine self-administration more slowly and had downward shifts in FR and PR cocaine dose-response curves." | 5.43 | Adolescent d-amphetamine treatment in a rodent model of attention deficit/hyperactivity disorder: impact on cocaine abuse vulnerability in adulthood. ( Dwoskin, LP; Jordan, CJ; Kantak, KM; Lemay, C, 2016) |
| " COMT, D4 receptor, and BDNF polymorphisms are linked to methamphetamine abuse and psychosis." | 4.85 | Pharmacogenetic treatments for drug addiction: cocaine, amphetamine and methamphetamine. ( Haile, CN; Kosten, TA; Kosten, TR, 2009) |
| "Attention-deficit/hyperactivity disorder (ADHD) is comorbid with cocaine abuse." | 3.83 | Adolescent D-amphetamine treatment in a rodent model of ADHD: Pro-cognitive effects in adolescence without an impact on cocaine cue reactivity in adulthood. ( Dwoskin, LP; Jordan, CJ; Kantak, KM; Taylor, DM, 2016) |
| "Chronic amphetamine treatment reduces cocaine self-administration in pre-clinical and clinical settings, and amphetamine has been proposed as a candidate medication for treatment of cocaine abuse." | 3.80 | The effect of chronic amphetamine treatment on cocaine-induced facilitation of intracranial self-stimulation in rats. ( Banks, ML; Bauer, CT; Negus, SS, 2014) |
| "From 1998 to 2004, the hospitalization ratio for cocaine abuse decreased 44%, whereas the hospitalization ratio for amphetamine abuse doubled." | 3.74 | Hospitalizations with amphetamine abuse among pregnant women. ( Cox, S; Jamieson, DJ; Kourtis, AP; Posner, SF, 2008) |
| "Cocaine dependence is a substantial public health problem, yet there are no clearly effective medication treatments." | 2.77 | Extended-release mixed amphetamine salts and topiramate for cocaine dependence: a randomized controlled trial. ( Bisaga, A; Brooks, DJ; Levin, FR; Mariani, JJ; Nunes, EV; Pavlicova, M, 2012) |
| "Amphetamine treatment also reversed escalated cocaine intake and decreased motivation to obtain cocaine as measured in a behavioral economics task, thereby linking tolerance to multiple facets of cocaine use." | 1.48 | Amphetamine Reverses Escalated Cocaine Intake via Restoration of Dopamine Transporter Conformation. ( Calipari, ES; Chen, R; Fordahl, SC; Jones, SR; Khoshbouei, H; Saha, K; Siciliano, CA, 2018) |
| "Mice treated with nicotine during early but not late adolescence showed an increase in CPP for cocaine, morphine and amphetamine later in adulthood." | 1.43 | Early adolescent nicotine exposure affects later-life cocaine reward in mice. ( Alajaji, M; Carroll, FI; Damaj, MI; Kota, D; Lazenka, MF; Levine, A; Selley, DE; Sim-Selley, LJ; Wise, LE; Younis, RM, 2016) |
| " Relative to vehicle, SHR and WIS with adolescent d-amphetamine treatment self-administered less cocaine upon reaching acquisition criteria, and WIS additionally acquired cocaine self-administration more slowly and had downward shifts in FR and PR cocaine dose-response curves." | 1.43 | Adolescent d-amphetamine treatment in a rodent model of attention deficit/hyperactivity disorder: impact on cocaine abuse vulnerability in adulthood. ( Dwoskin, LP; Jordan, CJ; Kantak, KM; Lemay, C, 2016) |
| " If these findings can be shown to extend to mammals, beta-lactam antibiotics might represent a novel pharmacotherapy or adjunct approach for treating drug abuse or serve as a template for drug discovery efforts aimed at treating drug abuse, recovery from drug abuse, or ameliorating the withdrawal from chronic use of therapeutic medications." | 1.35 | The beta-lactam antibiotic ceftriaxone inhibits physical dependence and abstinence-induced withdrawal from cocaine, amphetamine, methamphetamine, and clorazepate in planarians. ( Capasso, A; Cavallo, F; Ding, Z; Raffa, RB; Rawls, SM, 2008) |
| "Cocaine dependence is associated with impairment of dopamine function, and this impairment appears to play a critical role in relapse." | 1.34 | Amphetamine-induced dopamine release: markedly blunted in cocaine dependence and predictive of the choice to self-administer cocaine. ( Broft, A; Cooper, TB; Fischman, MW; Foltin, RW; Huang, Y; Hwang, DR; Kleber, HD; Laruelle, M; Martinez, D; Narendran, R; Slifstein, M, 2007) |
| "The 'heroin shortage' was unlikely to have been a simple correction at the end of a long period of reduced heroin availability, and represents a separate non-random shock which strongly affected the markets." | 1.33 | Identification and quantification of change in Australian illicit drug markets. ( Day, C; Degenhardt, L; Gilmour, S; Koch, I, 2006) |
| "The aim of this study was the assessment of disorders after chronic intake of psychoactive drugs, like marijuana, amphetamine, ecstasy, cocaine and opiates." | 1.32 | [Assessment of disorders after chronic psychoactive drug abuse in patients hospitalized in detoxification units]. ( Chrostek Maj, J; Kamenczak, A; Kroch, S; Polewka, A; Szerszeń-Motyka, J, 2004) |
| " Here we demonstrate that, after chronic administration of the psychostimulants cocaine and amphetamine, the transcription factor DeltaFosB is upregulated in the nucleus accumbens of periadolescent mice but not in post-weanling or adult mice." | 1.31 | Periadolescent mice show enhanced DeltaFosB upregulation in response to cocaine and amphetamine. ( Canas, E; Ehrlich, ME; Sommer, J; Unterwald, EM, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (8.06) | 18.2507 |
| 2000's | 31 (50.00) | 29.6817 |
| 2010's | 19 (30.65) | 24.3611 |
| 2020's | 7 (11.29) | 2.80 |
| Authors | Studies |
|---|---|
| Garcia, EJ | 1 |
| Cain, ME | 1 |
| Helander, A | 1 |
| Villén, T | 1 |
| Signell, P | 1 |
| Tschudi, L | 1 |
| Fischer, SKM | 1 |
| Perlov, E | 1 |
| Baumgartner, MR | 1 |
| Soyka, M | 1 |
| Müller, TJ | 1 |
| Seifritz, E | 1 |
| Mutschler, J | 1 |
| Narendran, R | 2 |
| Mason, NS | 1 |
| Himes, ML | 1 |
| Frankle, WG | 1 |
| Allain, F | 1 |
| Delignat-Lavaud, B | 1 |
| Beaudoin, MP | 1 |
| Jacquemet, V | 1 |
| Robinson, TE | 3 |
| Trudeau, LE | 1 |
| Samaha, AN | 1 |
| Brandt, L | 1 |
| Chao, T | 1 |
| Comer, SD | 1 |
| Levin, FR | 3 |
| Zakiniaeiz, Y | 1 |
| Cosgrove, KP | 1 |
| Kohut, SJ | 1 |
| Jacobs, DS | 1 |
| Rothman, RB | 2 |
| Partilla, JS | 1 |
| Bergman, J | 1 |
| Blough, BE | 1 |
| Siciliano, CA | 2 |
| Saha, K | 1 |
| Calipari, ES | 1 |
| Fordahl, SC | 2 |
| Chen, R | 1 |
| Khoshbouei, H | 1 |
| Jones, SR | 2 |
| Chen, SJ | 1 |
| Liao, DL | 1 |
| Chen, CH | 1 |
| Wang, TY | 1 |
| Chen, KC | 1 |
| Mauterer, MI | 1 |
| Lappin, JM | 1 |
| Sara, GE | 1 |
| Saunders, BT | 1 |
| Yager, LM | 1 |
| Bauer, CT | 1 |
| Banks, ML | 1 |
| Negus, SS | 1 |
| Jordan, CJ | 2 |
| Taylor, DM | 1 |
| Dwoskin, LP | 2 |
| Kantak, KM | 2 |
| Alajaji, M | 1 |
| Lazenka, MF | 1 |
| Kota, D | 1 |
| Wise, LE | 1 |
| Younis, RM | 1 |
| Carroll, FI | 1 |
| Levine, A | 1 |
| Selley, DE | 1 |
| Sim-Selley, LJ | 1 |
| Damaj, MI | 1 |
| Lemay, C | 1 |
| Notzon, DP | 1 |
| Mariani, JJ | 2 |
| Pavlicova, M | 2 |
| Glass, A | 1 |
| Mahony, AL | 1 |
| Brooks, DJ | 2 |
| Grabowski, J | 1 |
| Stanis, JJ | 1 |
| Burns, RM | 1 |
| Sherrill, LK | 1 |
| Gulley, JM | 1 |
| Nechifor, M | 1 |
| Crombag, HS | 1 |
| Ferrario, CR | 1 |
| Vocci, FJ | 1 |
| Montoya, ID | 1 |
| Haile, CN | 1 |
| Kosten, TR | 1 |
| Kosten, TA | 1 |
| Napper, LE | 1 |
| Fisher, DG | 1 |
| Johnson, ME | 1 |
| Wood, MM | 1 |
| Moeller, FG | 1 |
| Steinberg, JL | 1 |
| Schmitz, JM | 1 |
| Ma, L | 1 |
| Liu, S | 1 |
| Kjome, KL | 1 |
| Rathnayaka, N | 1 |
| Kramer, LA | 1 |
| Narayana, PA | 1 |
| Brunt, TM | 1 |
| van Laar, M | 1 |
| Niesink, RJ | 1 |
| van den Brink, W | 1 |
| Halbout, B | 1 |
| Quarta, D | 1 |
| Valerio, E | 1 |
| Heidbreder, CA | 2 |
| Hutcheson, DM | 1 |
| Ciccarone, D | 1 |
| Rácz, J | 1 |
| Csák, R | 1 |
| Faragó, R | 1 |
| Vadász, V | 1 |
| Bisaga, A | 1 |
| Nunes, EV | 1 |
| Volkow, ND | 1 |
| Wu, WR | 1 |
| Li, N | 1 |
| Sorg, BA | 1 |
| Ehrlich, ME | 1 |
| Sommer, J | 1 |
| Canas, E | 1 |
| Unterwald, EM | 1 |
| Miquel, M | 1 |
| Font, L | 1 |
| Sanchis-Segura, C | 1 |
| Aragon, CM | 1 |
| Stanwood, GD | 1 |
| Levitt, P | 1 |
| Homberg, JR | 1 |
| Raasø, HS | 1 |
| Schoffelmeer, AN | 2 |
| de Vries, TJ | 2 |
| Covington, HE | 1 |
| Kikusui, T | 1 |
| Goodhue, J | 1 |
| Nikulina, EM | 1 |
| Hammer, RP | 1 |
| Miczek, KA | 1 |
| Chrostek Maj, J | 1 |
| Kroch, S | 1 |
| Kamenczak, A | 1 |
| Polewka, A | 1 |
| Szerszeń-Motyka, J | 1 |
| Canales, JJ | 1 |
| Heusner, CL | 1 |
| Palmiter, RD | 1 |
| Cunha-Oliveira, T | 1 |
| Rego, AC | 1 |
| Cardoso, SM | 1 |
| Borges, F | 1 |
| Swerdlow, RH | 1 |
| Macedo, T | 1 |
| de Oliveira, CR | 1 |
| Peretti-Watel, P | 1 |
| Spire, B | 1 |
| Lert, F | 1 |
| Obadia, Y | 1 |
| Gilmour, S | 1 |
| Koch, I | 1 |
| Degenhardt, L | 1 |
| Day, C | 1 |
| Baumann, MH | 1 |
| Ukairo, OT | 1 |
| Ramanujapuram, S | 1 |
| Surratt, CK | 1 |
| Martinez, D | 2 |
| Foltin, RW | 1 |
| Slifstein, M | 1 |
| Hwang, DR | 1 |
| Broft, A | 1 |
| Huang, Y | 1 |
| Cooper, TB | 1 |
| Fischman, MW | 1 |
| Kleber, HD | 1 |
| Laruelle, M | 2 |
| Kollins, SH | 1 |
| Cole, JC | 1 |
| Goudie, AJ | 1 |
| Field, M | 1 |
| Loverseed, AC | 1 |
| Charlton, S | 1 |
| Sumnall, HR | 1 |
| Ersche, KD | 1 |
| Roiser, JP | 1 |
| Robbins, TW | 1 |
| Sahakian, BJ | 1 |
| Cox, S | 1 |
| Posner, SF | 1 |
| Kourtis, AP | 1 |
| Jamieson, DJ | 1 |
| Rawls, SM | 1 |
| Cavallo, F | 1 |
| Capasso, A | 1 |
| Ding, Z | 1 |
| Raffa, RB | 1 |
| Petitti, DB | 1 |
| Sidney, S | 1 |
| Quesenberry, C | 1 |
| Bernstein, A | 1 |
| Hurd, YL | 1 |
| Svensson, P | 1 |
| Pontén, M | 1 |
| Schenk, S | 1 |
| Partridge, B | 1 |
| Shippenberg, TS | 2 |
| Christensen, HR | 2 |
| Hedetoft, C | 1 |
| Sutton, MA | 1 |
| Karanian, DA | 1 |
| Self, DW | 1 |
| Tzschentke, TM | 1 |
| Schmidt, WJ | 1 |
| Gelernter, J | 1 |
| Abi-Dargham, A | 1 |
| van Dyck, CH | 1 |
| Kegeles, L | 1 |
| Innis, RB | 1 |
| Carboni, E | 1 |
| Spielewoy, C | 1 |
| Vacca, C | 1 |
| Nosten-Bertrand, M | 1 |
| Giros, B | 1 |
| Di Chiara, G | 1 |
| Chefer, VI | 1 |
| Zapata, A | 1 |
| Wardeh, G | 1 |
| van de Ven, HW | 1 |
| Vanderschuren, LJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Trial of an Antiretroviral Treatment Adherence Intervention for HIV+ African Americans[NCT03331978] | 306 participants (Actual) | Interventional | 2018-01-23 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Percentage of doses taken of those prescribed from electronic monitoring. Here we present all data collected at all time points used in analysis. Evaluation of intervention efficacy was performed with repeated measures regression using continuous adherence measurements at all 6 months post-intervention (7th through 12th month post-baseline) and was restricted to those with adherence data at baseline. (NCT03331978)
Timeframe: baseline (pre-treatment) and post-treatment observations at 7, 8, 9, 10, 11, and 12 months post-baseline
| Intervention | percentage of doses taken (Mean) | |||||
|---|---|---|---|---|---|---|
| 7 months post-baseline | 8 months post-baseline | 9 months post-baseline | 10 months post-baseline | 11 months post-baseline | 12 months post-baseline | |
| Control - No Treatment Education | 70.95 | 70.02 | 64.62 | 71.08 | 63.76 | 70.46 |
| Rise - Treatment Education | 68.80 | 72.76 | 72.09 | 71.27 | 69.87 | 70.32 |
Number of Participants who Reported Taking Greater Than or Equal to 75% of Prescribed Dosage, based on electronic monitoring. Here we present all data collected at all time points used in analysis. Evaluation of intervention efficacy was performed with repeated measures regression using adherence measurements at all 6 months post-intervention (7th through 12th month post-baseline) and was restricted to those with adherence data at baseline. (NCT03331978)
Timeframe: baseline (pre-treatment) and post-treatment observations at 7, 8, 9, 10, 11, and 12 months post-baseline
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| 7 months post-baseline | 8 months post-baseline | 9 months post-baseline | 10 months post-baseline | 11 months post-baseline | 12 months post-baseline | |
| Control - No Treatment Education | 43 | 40 | 38 | 32 | 29 | 28 |
| Rise - Treatment Education | 45 | 44 | 43 | 42 | 40 | 37 |
"Measure is count of participants who slightly agree or strongly agree with either Most people with AIDS are responsible for having their illness or A person with AIDS must have done something wrong and deserves to be punished." (NCT03331978)
Timeframe: baseline (pre-treatment) and post-treatment observations at 7 and 12 months post-baseline
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| 7 months post-baseline | 12 months post-baseline | |
| Control - No Treatment Education | 29 | 26 |
| Rise - Treatment Education | 25 | 15 |
Outcome is mean agreement with 9 HIV-related conspiracy beliefs, each measured on a 5-point scale from 1=Strongly Disagree to 5=Strongly Agree. (NCT03331978)
Timeframe: baseline (pre-treatment) and post-treatment observations at 7 and 12 months post-baseline
| Intervention | score on a scale (Mean) | |
|---|---|---|
| 7 months post-baseline | 12 months post-baseline | |
| Control - No Treatment Education | 2.65 | 2.56 |
| Rise - Treatment Education | 2.62 | 2.41 |
Viral load undetectable per venipuncture or medical records (NCT03331978)
Timeframe: baseline (pre-treatment) and post-treatment observations at 7 and 12 months post-baseline. For 7M, medical records were used if within 90 days of survey completion; for 13 months, medical records were used if within 90 days before or 180 days after survey
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| 7 month post-baseline | 12 month post-baseline | |
| Control - No Treatment Education | 60 | 56 |
| Rise - Treatment Education | 45 | 50 |
11 reviews available for amphetamine and Cocaine Abuse
| Article | Year |
|---|---|
Psychostimulant use and the brain.
Topics: Amphetamine; Amphetamine-Related Disorders; Brain; Central Nervous System Stimulants; Cocaine; Cocai | 2019 |
Magnesium in drug dependences.
Topics: Amphetamine; Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Magnesium; Models, Bi | 2008 |
Psychological treatments for stimulant misuse, comparing and contrasting those for amphetamine dependence and those for cocaine dependence.
Topics: Amphetamine; Central Nervous System Stimulants; Cocaine-Related Disorders; Cognitive Behavioral Ther | 2009 |
Pharmacogenetic treatments for drug addiction: cocaine, amphetamine and methamphetamine.
Topics: Amphetamine; Amphetamine-Related Disorders; Cocaine-Related Disorders; Disulfiram; Dopamine Uptake I | 2009 |
Stimulant abuse: pharmacology, cocaine, methamphetamine, treatment, attempts at pharmacotherapy.
Topics: Amphetamine; Amphetamine-Related Disorders; Central Nervous System Stimulants; Cocaine; Cocaine-Rela | 2011 |
Stimulant-induced adaptations in neostriatal matrix and striosome systems: transiting from instrumental responding to habitual behavior in drug addiction.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Arousal; Basal Ganglia; Central Nervous System | 2005 |
Balance between dopamine and serotonin release modulates behavioral effects of amphetamine-type drugs.
Topics: Amphetamine; Animals; Behavior, Addictive; Cocaine-Related Disorders; Dopamine; Dopamine Agents; Hap | 2006 |
ADHD, substance use disorders, and psychostimulant treatment: current literature and treatment guidelines.
Topics: Amphetamine; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child | 2008 |
The role of dopamine, dynorphin, and CART systems in the ventral striatum and amygdala in cocaine abuse.
Topics: Amphetamine; Amygdala; Animals; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Dopamine; Dynor | 1999 |
[Amphetamine, ecstasy and cocaine. Clinical aspects of acute poisoning].
Topics: Amphetamine; Amphetamine-Related Disorders; Central Nervous System Stimulants; Cocaine; Cocaine-Rela | 1999 |
Modulation of the behavioral and neurochemical effects of psychostimulants by kappa-opioid receptor systems.
Topics: Adaptation, Psychological; Affect; Amphetamine; Animals; Basal Ganglia; Brain Chemistry; Cocaine; Co | 2001 |
3 trials available for amphetamine and Cocaine Abuse
| Article | Year |
|---|---|
Mixed-amphetamine salts increase abstinence from marijuana in patients with co-occurring attention-deficit/hyperactivity disorder and cocaine dependence.
Topics: Adult; Amphetamine; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants | 2016 |
Working memory fMRI activation in cocaine-dependent subjects: association with treatment response.
Topics: Adult; Amphetamine; Analysis of Variance; Benzhydryl Compounds; Brain; Brain Mapping; Carbidopa; Cen | 2010 |
Extended-release mixed amphetamine salts and topiramate for cocaine dependence: a randomized controlled trial.
Topics: Adolescent; Adult; Amphetamine; Cocaine-Related Disorders; Delayed-Action Preparations; Double-Blind | 2012 |
48 other studies available for amphetamine and Cocaine Abuse
| Article | Year |
|---|---|
Isolation housing elevates amphetamine seeking independent of nucleus accumbens glutamate receptor adaptations.
Topics: Amphetamine; Animals; Cocaine; Cocaine-Related Disorders; Cues; Drug-Seeking Behavior; Extinction, P | 2021 |
Urine Drug Tests Indicate Higher Prevalence of Combined Alcohol and Cocaine Use Compared to Alcohol Together with Cannabis or Amphetamine-A Possible Link to Cocaethylene.
Topics: Amphetamine; Cannabis; Chromatography, Liquid; Cocaine; Cocaine-Related Disorders; Ethanol; Humans; | 2023 |
Concomitant Drug Use among Opioid-Dependent Patients with and without Attention Deficit Hyperactivity Disorder: Does Methylphenidate Merit a Trial?
Topics: Amphetamine; Analgesics, Opioid; Attention Deficit Disorder with Hyperactivity; Central Nervous Syst | 2023 |
Imaging Cortical Dopamine Transmission in Cocaine Dependence: A [
Topics: Amphetamine; Cocaine-Related Disorders; Dopamine; Humans; Kinetics; Positron-Emission Tomography; Py | 2020 |
Amphetamine maintenance therapy during intermittent cocaine self-administration in rats attenuates psychomotor and dopamine sensitization and reduces addiction-like behavior.
Topics: Amphetamine; Animals; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Uptake Inhibitors; Male | 2021 |
Pharmacotherapeutic strategies for treating cocaine use disorder-what do we have to offer?
Topics: Amphetamine; Cocaine; Cocaine-Related Disorders; Humans; Substance-Related Disorders; Topiramate | 2021 |
Designing Neuroimaging Studies to Help Inform the Clinical Treatment of Addiction.
Topics: Amphetamine; Carbon Radioisotopes; Cocaine-Related Disorders; Dopamine; Humans; Neuroimaging; Positr | 2020 |
Cocaine-like discriminative stimulus effects of "norepinephrine-preferring" monoamine releasers: time course and interaction studies in rhesus monkeys.
Topics: Amphetamine; Animals; Cocaine; Cocaine-Related Disorders; Discrimination Learning; Dopamine; Dopamin | 2017 |
Amphetamine Reverses Escalated Cocaine Intake via Restoration of Dopamine Transporter Conformation.
Topics: Amphetamine; Animals; Cocaine-Related Disorders; Dopamine Plasma Membrane Transport Proteins; Drug T | 2018 |
Construction and Analysis of Protein-Protein Interaction Network of Heroin Use Disorder.
Topics: Alcoholism; Amphetamine; Cocaine-Related Disorders; Genetic Predisposition to Disease; Heroin Depend | 2019 |
Modulation of striatal dopamine dynamics by cocaine self-administration and amphetamine treatment in female rats.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Corpus | 2019 |
Cue-evoked cocaine "craving": role of dopamine in the accumbens core.
Topics: Amphetamine; Animals; Cocaine; Cocaine-Related Disorders; Cues; Dopamine; Dopamine Antagonists; Drug | 2013 |
The effect of chronic amphetamine treatment on cocaine-induced facilitation of intracranial self-stimulation in rats.
Topics: Amphetamine; Animals; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Implantable Ne | 2014 |
Adolescent D-amphetamine treatment in a rodent model of ADHD: Pro-cognitive effects in adolescence without an impact on cocaine cue reactivity in adulthood.
Topics: Aging; Amphetamine; Animals; Attention Deficit Disorder with Hyperactivity; Central Nervous System S | 2016 |
Early adolescent nicotine exposure affects later-life cocaine reward in mice.
Topics: Aging; Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; | 2016 |
Adolescent d-amphetamine treatment in a rodent model of attention deficit/hyperactivity disorder: impact on cocaine abuse vulnerability in adulthood.
Topics: Amphetamine; Analysis of Variance; Animals; Attention Deficit Disorder with Hyperactivity; Central N | 2016 |
Disparate cocaine-induced locomotion as a predictor of choice behavior in rats trained in a delay-discounting task.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Animals; Choice Behavior; Cocaine; Cocaine-Rela | 2008 |
The rate of intravenous cocaine or amphetamine delivery does not influence drug-taking and drug-seeking behavior in rats.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Body Temperature; Cocaine; Cocaine-Related Diso | 2008 |
The reliability and validity of drug users' self reports of amphetamine use among primarily heroin and cocaine users.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amphetamine; Amphetamine-Related Disorders; Cocaine-Rela | 2010 |
The relationship of quality and price of the psychostimulants cocaine and amphetamine with health care outcomes.
Topics: Adult; Amphetamine; Amphetamine-Related Disorders; Cocaine; Cocaine-Related Disorders; Commerce; Fem | 2010 |
The GABA-B positive modulator GS39783 decreases psychostimulant conditioned-reinforcement and conditioned-reward.
Topics: Allosteric Regulation; Amphetamine; Animals; Association Learning; Baclofen; Central Nervous System | 2011 |
[The phenomenon of drug change in the interviews with injecting drug users].
Topics: Adolescent; Adult; Amphetamine; Cocaine; Cocaine-Related Disorders; Designer Drugs; Dopamine Uptake | 2012 |
Long-term safety of stimulant use for ADHD: findings from nonhuman primates.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine-Related Disorders | 2012 |
Regulation of medial prefrontal cortex dopamine by alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amphetamine; Animals; Cocaine; Cocaine-Related Disorders; Dopa | 2002 |
Periadolescent mice show enhanced DeltaFosB upregulation in response to cocaine and amphetamine.
Topics: Age Factors; Aging; Amphetamine; Amphetamine-Related Disorders; Animals; Caudate Nucleus; Cocaine; C | 2002 |
Neonatal administration of monosodium glutamate prevents the development of ethanol- but not psychostimulant-induced sensitization: a putative role of the arcuate nucleus.
Topics: Alcoholism; Amphetamine; Amphetamine-Related Disorders; Animals; Animals, Newborn; Arcuate Nucleus o | 2003 |
Repeated i.v. cocaine exposure produces long-lasting behavioral sensitization in pregnant adults, but behavioral tolerance in their offspring.
Topics: Amphetamine; Animals; Animals, Newborn; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dopami | 2003 |
Individual differences in sensitivity to factors provoking reinstatement of cocaine-seeking behavior.
Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Addictive; Behavior, Animal; Central Nervous S | 2004 |
Brief social defeat stress: long lasting effects on cocaine taking during a binge and zif268 mRNA expression in the amygdala and prefrontal cortex.
Topics: Amphetamine; Amygdala; Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorder | 2005 |
[Assessment of disorders after chronic psychoactive drug abuse in patients hospitalized in detoxification units].
Topics: Adolescent; Adult; Amphetamine; Amphetamine-Related Disorders; Cannabis; Cocaine; Cocaine-Related Di | 2004 |
Expression of mutant NMDA receptors in dopamine D1 receptor-containing cells prevents cocaine sensitization and decreases cocaine preference.
Topics: Amino Acid Substitution; Amphetamine; Animals; Brain; Central Nervous System Stimulants; Chromosomes | 2005 |
Mitochondrial dysfunction and caspase activation in rat cortical neurons treated with cocaine or amphetamine.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Apoptosis; Caspases; Cell Line, Tumor; Central | 2006 |
Drug use patterns and adherence to treatment among HIV-positive patients: evidence from a large sample of French outpatients (ANRS-EN12-VESPA 2003).
Topics: Adult; Amphetamine; Antiretroviral Therapy, Highly Active; Cluster Analysis; Cocaine-Related Disorde | 2006 |
Identification and quantification of change in Australian illicit drug markets.
Topics: Amphetamine; Amphetamine-Related Disorders; Cluster Analysis; Cocaine; Cocaine-Related Disorders; Dr | 2006 |
Fluctuation of the dopamine uptake inhibition potency of cocaine, but not amphetamine, at mammalian cells expressing the dopamine transporter.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Benztropine; Binding, Competitive; Brain; Brain | 2007 |
Amphetamine-induced dopamine release: markedly blunted in cocaine dependence and predictive of the choice to self-administer cocaine.
Topics: Adult; Amphetamine; Basal Ganglia; Carbon Radioisotopes; Choice Behavior; Cocaine; Cocaine-Related D | 2007 |
The effects of perceived quality on the behavioural economics of alcohol, amphetamine, cannabis, cocaine, and ecstasy purchases.
Topics: Adult; Alcohol Drinking; Amphetamine; Catchment Area, Health; Cocaine-Related Disorders; Commerce; C | 2008 |
Chronic cocaine but not chronic amphetamine use is associated with perseverative responding in humans.
Topics: Adolescent; Adult; Aged; Amphetamine; Amphetamine-Related Disorders; Appetitive Behavior; Associatio | 2008 |
Hospitalizations with amphetamine abuse among pregnant women.
Topics: Adolescent; Adult; Age Factors; Amphetamine; Amphetamine-Related Disorders; Chi-Square Distribution; | 2008 |
The beta-lactam antibiotic ceftriaxone inhibits physical dependence and abstinence-induced withdrawal from cocaine, amphetamine, methamphetamine, and clorazepate in planarians.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Anti-Bacterial Agents; Ceftriaxone; Clorazepate | 2008 |
Stroke and cocaine or amphetamine use.
Topics: Adolescent; Adult; Amphetamine; Central Nervous System Stimulants; Cerebrovascular Disorders; Cocain | 1998 |
U69593, a kappa-opioid agonist, decreases cocaine self-administration and decreases cocaine-produced drug-seeking.
Topics: Amphetamine; Animals; Behavior, Addictive; Benzeneacetamides; Cocaine-Related Disorders; Dopamine An | 1999 |
[Poisoning with central nervous system stimulants. Amphetamine, ecstasy, cocaine and gamma-hydroxybutyrate].
Topics: Amphetamine; Amphetamine-Related Disorders; Cocaine; Cocaine-Related Disorders; Denmark; Drug Overdo | 1999 |
Factors that determine a propensity for cocaine-seeking behavior during abstinence in rats.
Topics: Amphetamine; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dose-Response Relationsh | 2000 |
Differential effects of discrete subarea-specific lesions of the rat medial prefrontal cortex on amphetamine- and cocaine-induced behavioural sensitization.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Behavior, Animal; Cocaine; Cocaine-Related Diso | 2000 |
The variable number of tandem repeats polymorphism of the dopamine transporter gene is not associated with significant change in dopamine transporter phenotype in humans.
Topics: Adult; Amphetamine; Attention Deficit Disorder with Hyperactivity; Benzamides; Carrier Proteins; Coc | 2001 |
Cocaine and amphetamine increase extracellular dopamine in the nucleus accumbens of mice lacking the dopamine transporter gene.
Topics: Adrenergic Uptake Inhibitors; Amphetamine; Animals; Carrier Proteins; Chromatography, High Pressure | 2001 |
Psychostimulant-induced behavioral sensitization depends on nicotinic receptor activation.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Association Learning; Behavior, Animal; Central | 2002 |