Page last updated: 2024-10-25

amphetamine and Cerebrovascular Disorders

amphetamine has been researched along with Cerebrovascular Disorders in 12 studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.

Research Excerpts

ExcerptRelevanceReference
"In classical migraine (headache associated with prodromal visual field disturbances) and migraine accompagnée (headache associated with transient neurological symptoms), disturbances of cerebral blood flow and amine metabolism are thought to be pathogenetic factors."1.27123I-amphetamine-SPECT in classical migraine and migraine accompagnée. ( Böttger, I; Brune, G; Grotemeyer, KH; Husstedt, IW; Schlake, HP, 1987)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19908 (66.67)18.7374
1990's4 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
POPEK, K1
Sine, RD1
Soufi, A1
Shah, M1
Hassid, EI1
Feeney, DM1
Petitti, DB1
Sidney, S1
Quesenberry, C1
Bernstein, A1
Williams, RL1
Beaton, JM1
Pegram, GV1
Capra, N1
Halsey, JH1
Bradley, RJ1
Kaku, DA1
Lowenstein, DH1
Tsuda, Y1
Hartmann, A1
Biersack, HJ1
Valerius, E1
Reichmann, K1
Crisostomo, EA1
Duncan, PW1
Propst, M1
Dawson, DV1
Davis, JN1
Schlake, HP1
Grotemeyer, KH1
Böttger, I1
Husstedt, IW1
Brune, G1
Patel, AN1
Ciurea, E1
Crighel, E1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Neuroanatomical and Neurophysiological Basis of Motor Recovery Associated With Treatment of Recent Stroke Using Amphetamine and Physical Therapy[NCT00001783]Phase 234 participants Interventional1998-04-30Completed
Study of the Effects on Motor Recovery of Early Post-stroke Spasticity Treatment: Double Blinded Comparison Between Botulinum Toxin and Baclofen.[NCT02462317]Phase 4184 participants (Actual)Interventional2015-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for amphetamine and Cerebrovascular Disorders

ArticleYear
Neuropharmacological therapy and motor recovery after stroke.
    Military medicine, 1995, Volume: 160, Issue:5

    Topics: Amphetamine; Animals; Brain; Cerebrovascular Disorders; Desipramine; Humans; Motor Activity; Motor N

1995
From laboratory to clinic: noradrenergic enhancement of physical therapy for stroke or trauma patients.
    Advances in neurology, 1997, Volume: 73

    Topics: Adrenergic Agents; Amphetamine; Cerebrovascular Disorders; Humans; Physical Therapy Modalities; Woun

1997

Trials

1 trial available for amphetamine and Cerebrovascular Disorders

ArticleYear
Evidence that amphetamine with physical therapy promotes recovery of motor function in stroke patients.
    Annals of neurology, 1988, Volume: 23, Issue:1

    Topics: Aged; Amphetamine; Cerebrovascular Disorders; Evaluation Studies as Topic; Humans; Middle Aged; Move

1988
Evidence that amphetamine with physical therapy promotes recovery of motor function in stroke patients.
    Annals of neurology, 1988, Volume: 23, Issue:1

    Topics: Aged; Amphetamine; Cerebrovascular Disorders; Evaluation Studies as Topic; Humans; Middle Aged; Move

1988
Evidence that amphetamine with physical therapy promotes recovery of motor function in stroke patients.
    Annals of neurology, 1988, Volume: 23, Issue:1

    Topics: Aged; Amphetamine; Cerebrovascular Disorders; Evaluation Studies as Topic; Humans; Middle Aged; Move

1988
Evidence that amphetamine with physical therapy promotes recovery of motor function in stroke patients.
    Annals of neurology, 1988, Volume: 23, Issue:1

    Topics: Aged; Amphetamine; Cerebrovascular Disorders; Evaluation Studies as Topic; Humans; Middle Aged; Move

1988

Other Studies

9 other studies available for amphetamine and Cerebrovascular Disorders

ArticleYear
THE STUDY OF CHANGES IN THE SO-CALLED SUCCESSIVE CONTRAST IN NEUROLOGY.
    Activitas nervosa superior, 1964, Volume: 6

    Topics: Afterimage; Amphetamine; Arteriosclerosis; Brain Concussion; Brain Injuries; Brain Neoplasms; Bromid

1964
Callosal syndrome: implications for understanding the neuropsychology of stroke.
    Archives of physical medicine and rehabilitation, 1984, Volume: 65, Issue:10

    Topics: Adult; Amphetamine; Apraxias; Cerebrovascular Disorders; Corpus Callosum; Dominance, Cerebral; Human

1984
Stroke and cocaine or amphetamine use.
    Epidemiology (Cambridge, Mass.), 1998, Volume: 9, Issue:6

    Topics: Adolescent; Adult; Amphetamine; Central Nervous System Stimulants; Cerebrovascular Disorders; Cocain

1998
Amphetamine induced turning behavior as an index of stroke in the Mongolian gerbil.
    Experientia, 1977, May-15, Volume: 33, Issue:5

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Carotid Arteries; Cerebrovascular Disorders; Di

1977
Emergence of recreational drug abuse as a major risk factor for stroke in young adults.
    Annals of internal medicine, 1990, Dec-01, Volume: 113, Issue:11

    Topics: Adolescent; Adult; Amphetamine; Case-Control Studies; Cerebral Hemorrhage; Cerebrovascular Disorders

1990
Assessment of regional cerebral blood flow with 123I amphetamine single photon emission computed tomography in cerebrovascular disease. Semiquantitative analysis comparing IMP SPECT with the 133Xe inhalation method.
    Acta radiologica. Supplementum, 1986, Volume: 369

    Topics: Amphetamine; Cerebrovascular Circulation; Cerebrovascular Disorders; Humans; Iodine Radioisotopes; M

1986
123I-amphetamine-SPECT in classical migraine and migraine accompagnée.
    Neurosurgical review, 1987, Volume: 10, Issue:3

    Topics: Adolescent; Adult; Amphetamine; Basilar Artery; Cerebrovascular Disorders; Female; Hemiplegia; Human

1987
Self-inflicted strokes.
    Annals of internal medicine, 1972, Volume: 76, Issue:5

    Topics: Amphetamine; Animals; Cerebral Angiography; Cerebrovascular Disorders; Fundus Oculi; Haplorhini; Hum

1972
Neurogenic mechanisms in the evolution of cerebral circulatory insufficiency. Investigations on the role of the brain stem reticular formation.
    Confinia neurologica, 1967, Volume: 29, Issue:6

    Topics: Amphetamine; Basilar Artery; Blood Pressure; Carotid Artery Diseases; Cerebrovascular Circulation; C

1967