Page last updated: 2024-10-25

amphetamine and Cataleptic Attacks

amphetamine has been researched along with Cataleptic Attacks in 15 studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Research Excerpts

ExcerptRelevanceReference
"Cataplexy was not affected by amphetamine treatment, but was abolished in two patients when clomipramine was given together with either amphetamine."6.64Levo(-) amphetamine and dextro(+) amphetamine in the treatment of narcolepsy. ( Fenton, GW; Parkes, JD, 1973)
"Cataplexy was not affected by amphetamine treatment, but was abolished in two patients when clomipramine was given together with either amphetamine."2.64Levo(-) amphetamine and dextro(+) amphetamine in the treatment of narcolepsy. ( Fenton, GW; Parkes, JD, 1973)
"We found that cataplexy is modulated by a D2-like receptor mechanism, whereas dopamine modulates sleep attacks by a D1-like receptor mechanism."1.36Dopaminergic regulation of sleep and cataplexy in a murine model of narcolepsy. ( Burgess, CR; Gillis, L; Peever, JH; Tse, G, 2010)
"D-Amphetamine was found to be more potent in increasing DA efflux than L-amphetamine, and L-methamphetamine was found to have little effect on DA efflux; there was no significant difference in the potencies of the three derivatives on NE efflux."1.31Implication of dopaminergic mechanisms in the wake-promoting effects of amphetamine: a study of D- and L-derivatives in canine narcolepsy. ( Honda, K; Kanbayashi, T; Kodama, T; Mignot, E; Nishino, S, 2000)
"In contrast, the results of cataplexy testing demonstrate that amphetamine (2."1.29Comparative effects of modafinil and amphetamine on daytime sleepiness and cataplexy of narcoleptic dogs. ( Dement, WC; Mignot, E; Nishino, S; Shelton, J; Vaught, J, 1995)
"NARCOLEPSY IS A DISORDER OF SLEEP CONTROL CHARACTERIZED BY A TETRAD OF SYMPTOMS: sleep attacks, cataplexy, sleep paralysis and hypnagogic hallucinations."1.25Narcolepsy. ( Foley, A; Murray, TJ, 1974)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199010 (66.67)18.7374
1990's2 (13.33)18.2507
2000's1 (6.67)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Krishnamurthy, VB1
Nallamothu, V1
Singareddy, R1
Burgess, CR1
Tse, G1
Gillis, L1
Peever, JH1
CRUMP, GP1
Shelton, J1
Nishino, S2
Vaught, J1
Dement, WC2
Mignot, E2
Kanbayashi, T1
Honda, K1
Kodama, T1
Lange, KW1
Roth, B2
Faber, J2
Nevsímalová, S2
Tosovský, J2
Kuhlo, W1
Zarcone, V1
Guilleminault, C1
Carskadon, M1
Parkes, JD2
Fenton, GW1
Fenton, G1
Struthers, G1
Curzon, G1
Kantamaneni, BD1
Buxton, BH1
Record, C1
Murray, TJ1
Foley, A1
Jovanović, UJ1

Reviews

3 reviews available for amphetamine and Cataleptic Attacks

ArticleYear
[Narcolepsy].
    Deutsche medizinische Wochenschrift (1946), 1990, Aug-17, Volume: 115, Issue:33

    Topics: Adolescent; Adult; Amphetamine; Cataplexy; Child; Clomipramine; Diagnosis, Differential; Female; Hum

1990
[Nacolepsy an its therapy].
    Deutsche medizinische Wochenschrift (1946), 1971, Jul-30, Volume: 96, Issue:31

    Topics: Amphetamine; Barbiturates; Cataplexy; Drug Tolerance; Electroencephalography; Humans; Imipramine; Mo

1971
Narcolepsy.
    The New England journal of medicine, 1973, May-31, Volume: 288, Issue:22

    Topics: Adolescent; Adult; Amphetamine; Cataplexy; Child; Diagnosis, Differential; Female; Hallucinations; H

1973

Trials

1 trial available for amphetamine and Cataleptic Attacks

ArticleYear
Levo(-) amphetamine and dextro(+) amphetamine in the treatment of narcolepsy.
    Journal of neurology, neurosurgery, and psychiatry, 1973, Volume: 36, Issue:6

    Topics: Adult; Amphetamine; Antidepressive Agents; Cataplexy; Dextroamphetamine; Electroencephalography; Eva

1973

Other Studies

11 other studies available for amphetamine and Cataleptic Attacks

ArticleYear
An interesting case of late age at onset of narcolepsy with cataplexy.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2014, Feb-15, Volume: 10, Issue:2

    Topics: Amphetamine; Cataplexy; Central Nervous System Stimulants; Dextroamphetamine; Diagnosis, Differentia

2014
Dopaminergic regulation of sleep and cataplexy in a murine model of narcolepsy.
    Sleep, 2010, Volume: 33, Issue:10

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Analysis of Variance; Anima

2010
NARCOLEPSY. A DISCUSSION AND CASE PRESENTATION.
    Proceedings of the Weekly Seminar in Neurology, 1963, Volume: 15

    Topics: Amphetamine; Amphetamines; Cataplexy; Diagnosis, Differential; Genetics, Medical; Hallucinations; Hu

1963
Comparative effects of modafinil and amphetamine on daytime sleepiness and cataplexy of narcoleptic dogs.
    Sleep, 1995, Volume: 18, Issue:10

    Topics: Amphetamine; Animals; Behavior, Animal; Benzhydryl Compounds; Cataplexy; Central Nervous System Stim

1995
Implication of dopaminergic mechanisms in the wake-promoting effects of amphetamine: a study of D- and L-derivatives in canine narcolepsy.
    Neuroscience, 2000, Volume: 99, Issue:4

    Topics: Amphetamine; Animals; Cataplexy; Caudate Nucleus; Central Nervous System Stimulants; Cerebral Cortex

2000
[Effect of imipramine, dexphenmetrazine and amphetamine sulfate on synchronous and paradoxical sleep in narcolepsy-cataplexy. A polygraphic study].
    Ceskoslovenska neurologie, 1970, Volume: 33, Issue:1

    Topics: Amphetamine; Cataplexy; Electroencephalography; Humans; Imipramine; Narcolepsy; Phenmetrazine; Sleep

1970
The influence of imipramine, dexphenmetrazine and amphetaminsulphate upon the clinical and polygraphic picture of narcolepsy-cataplexy.
    Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie, 1971, Volume: 108, Issue:2

    Topics: Amphetamine; Cataplexy; Electrocardiography; Electroencephalography; Electromyography; Electrooculog

1971
On the treatment of rapid eye movement narcolepsy.
    Archives of neurology, 1974, Volume: 30, Issue:1

    Topics: Adult; Amphetamine; Antidepressive Agents; Cataplexy; Depression; Desipramine; Electroencephalograph

1974
Narcolepsy and cataplexy. Clinical features, treatment and cerebrospinal fluid findings.
    The Quarterly journal of medicine, 1974, Volume: 43, Issue:172

    Topics: Adult; Amphetamine; Aspartic Acid; Body Weight; Cataplexy; Cerebrospinal Fluid Proteins; Dextroamphe

1974
Narcolepsy.
    Canadian Medical Association journal, 1974, Jan-05, Volume: 110, Issue:1

    Topics: Accidents, Traffic; Adult; Amphetamine; Automobile Driving; Cataplexy; Female; Hallucinations; Human

1974
[Subclinical sleep activity in the EEG].
    Psychiatria clinica, 1969, Volume: 2, Issue:6

    Topics: Adult; Amphetamine; Arousal; Brain Diseases; Cataplexy; Child; Child Behavior Disorders; Electroence

1969