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amphetamine and Brain Diseases

amphetamine has been researched along with Brain Diseases in 20 studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.

Research Excerpts

ExcerptRelevanceReference
"Schizophrenia is a neuropsychiatric disorder of a neurodevelopmental origin manifested symptomatically after puberty."5.35Clozapine administration in adolescence prevents postpubertal emergence of brain structural pathology in an animal model of schizophrenia. ( Assaf, Y; Piontkewitz, Y; Weiner, I, 2009)
"Schizophrenia is a neuropsychiatric disorder of a neurodevelopmental origin manifested symptomatically after puberty."1.35Clozapine administration in adolescence prevents postpubertal emergence of brain structural pathology in an animal model of schizophrenia. ( Assaf, Y; Piontkewitz, Y; Weiner, I, 2009)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19907 (35.00)18.7374
1990's7 (35.00)18.2507
2000's5 (25.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kanemaru, K1
Kinouchi, H1
Yoshioka, H1
Yagi, T1
Wakai, T1
Hashimoto, K1
Fukumoto, Y1
Umeda, T1
Onishi, H1
Nishiyama, Y1
Horikoshi, T1
Piontkewitz, Y1
Assaf, Y1
Weiner, I1
Olds, ME1
Jacques, DB1
Kpoyov, O1
CLANCY, J1
Moroz, IA1
Peciña, S1
Schallert, T1
Stewart, J1
Ouagazzal, A1
Nieoullon, A1
Amalric, M1
Sziráki, I1
Kardos, V1
Patthy, M1
Pátfalusi, M1
Budai, G1
Chambers, RA1
Moore, J1
McEvoy, JP1
Levin, ED1
Balse, E1
Suhr, R1
Haaf, A1
Kelche, C1
Jackisch, R1
Cassel, JC1
Joseph, MH1
Peters, SL1
Moran, PM1
Grigoryan, GA1
Young, AM1
Gray, JA1
Leviel, V1
Siever, L1
Kraemer, H1
Sack, R1
Angwin, P1
Berger, P1
Zarcone, V1
Barchas, J1
Brodie, HK1
Kolarík, J1
Pĕnicková, V1
Ohta, H1
Komibuchi, T1
Nishino, I1
Enomoto, Y1
Miyata, M1
Castañeda, E1
Whishaw, IQ1
Robinson, TE1
Meloni, R1
Gale, K1
Tennant, FS1
Swendseid, ME1
Shogam, II1
Jovanović, UJ1
Crighel, E1
Poilici, I1

Reviews

1 review available for amphetamine and Brain Diseases

ArticleYear
The reverse transport of DA, what physiological significance?
    Neurochemistry international, 2001, Volume: 38, Issue:2

    Topics: Amphetamine; Animals; Biological Transport, Active; Brain Diseases; Brain Ischemia; Corpus Striatum;

2001

Other Studies

19 other studies available for amphetamine and Brain Diseases

ArticleYear
Cerebral hemodynamic disturbance in dural arteriovenous fistula with retrograde leptomeningeal venous drainage: a prospective study using (123)I-iodoamphetamine single photon emission computed tomography.
    Journal of neurosurgery, 2015, Volume: 123, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amphetamine; Brain Diseases; Central Nervous System Vascular Malform

2015
Clozapine administration in adolescence prevents postpubertal emergence of brain structural pathology in an animal model of schizophrenia.
    Biological psychiatry, 2009, Dec-01, Volume: 66, Issue:11

    Topics: Abnormalities, Drug-Induced; Age Factors; Amphetamine; Animals; Antipsychotic Agents; Attention; Bra

2009
Behavioral/neurophysiological investigation of effects of combining a quinolinic acid entopeduncular lesion with a fetal mesencephalic tissue transplant in striatum of the 6-OHDA hemilesioned rat.
    Synapse (New York, N.Y.), 2003, Volume: 49, Issue:1

    Topics: Amphetamine; Animals; Apomorphine; Brain Diseases; Brain Tissue Transplantation; Corpus Striatum; Do

2003
OTHER ASPECTS OF DEPRESSION.
    Geriatrics, 1965, Volume: 20

    Topics: Alcoholism; Amphetamine; Antidepressive Agents; Barbiturates; Bipolar Disorder; Brain Diseases; Depr

1965
Sparing of behavior and basal extracellular dopamine after 6-hydroxydopamine lesions of the nigrostriatal pathway in rats exposed to a prelesion sensitizing regimen of amphetamine.
    Experimental neurology, 2004, Volume: 189, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Behav

2004
Locomotor activation induced by MK-801 in the rat: postsynaptic interactions with dopamine receptors in the ventral striatum.
    European journal of pharmacology, 1994, Jan-14, Volume: 251, Issue:2-3

    Topics: Amphetamine; Animals; Brain; Brain Diseases; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamin

1994
Methamphetamine protects against MPTP neurotoxicity in C57BL mice.
    European journal of pharmacology, 1994, Jan-14, Volume: 251, Issue:2-3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Amphetamine; Animals; Bra

1994
Cognitive effects of neonatal hippocampal lesions in a rat model of schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1996, Volume: 15, Issue:6

    Topics: Amphetamine; Animals; Behavior, Animal; Brain Diseases; Central Nervous System Stimulants; Disease M

1996
The potentiation of amphetamine-induced hyperlocomotion by fimbria-fornix lesions in rats is abolished by intrahippocampal grafts rich in serotonergic neurons.
    Neuroscience letters, 1999, Apr-16, Volume: 265, Issue:2

    Topics: Amphetamine; Animals; Brain Diseases; Choline; Drug Synergism; Electric Stimulation; Female; Frontal

1999
Modulation of latent inhibition in the rat by altered dopamine transmission in the nucleus accumbens at the time of conditioning.
    Neuroscience, 2000, Volume: 101, Issue:4

    Topics: Amphetamine; Animals; Association Learning; Behavior, Animal; Brain Diseases; Conditioning, Psycholo

2000
Gradients of biogenic amine metabolites in cerebrospinal fluid.
    Diseases of the nervous system, 1975, Volume: 36, Issue:1

    Topics: Alzheimer Disease; Amphetamine; Brain Diseases; Brain Neoplasms; Depression; Homovanillic Acid; Huma

1975
A contribution to the electrogenesis of distant rhythms in EEG.
    Activitas nervosa superior, 1975, Volume: 17, Issue:1

    Topics: Amphetamine; Brain; Brain Diseases; Cerebellar Neoplasms; Electroencephalography; Epilepsy; Humans;

1975
Brain perfusion abnormalities in a thinner and amphetamine abuser detected by I-123 IMP scintigraphy.
    Annals of nuclear medicine, 1992, Volume: 6, Issue:4

    Topics: Adult; Amphetamine; Amphetamines; Brain Diseases; Electroencephalography; Humans; Iodine Radioisotop

1992
Changes in striatal dopamine neurotransmission assessed with microdialysis following recovery from a bilateral 6-OHDA lesion: variation as a function of lesion size.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1990, Volume: 10, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Brain Diseases; Corpus Striatum; Dialysis; Dop

1990
Cocaine-induced turning behavior in rats with 6-hydroxydopamine lesions: effect of transplants of fetal substantia nigra.
    European journal of pharmacology, 1991, Dec-10, Volume: 209, Issue:1-2

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Diseases; Brain Tissue Transplantation; C

1991
Alterations in catecholamine metabolism partially corrected during amphetamine-dependence.
    Drug and alcohol dependence, 1985, Volume: 15, Issue:1-2

    Topics: Adult; Amphetamine; Brain Diseases; Catecholamines; Female; Humans; Neurocognitive Disorders; Self M

1985
[A study of sensation by the double simultaneous stimulation method].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1974, Volume: 74, Issue:9

    Topics: Adult; Amphetamine; Brain Diseases; Caffeine; Epinephrine; Female; Humans; Hypesthesia; Methods; Pai

1974
[Subclinical sleep activity in the EEG].
    Psychiatria clinica, 1969, Volume: 2, Issue:6

    Topics: Adult; Amphetamine; Arousal; Brain Diseases; Cataplexy; Child; Child Behavior Disorders; Electroence

1969
Photic evoked responses in patients with thalamic and brain stem lesions.
    Confinia neurologica, 1968, Volume: 30, Issue:5

    Topics: Adult; Aged; Amphetamine; Blindness; Blood Pressure; Brain Diseases; Brain Stem; Cerebral Cortex; El

1968