Page last updated: 2024-10-25

amphetamine and Autism

amphetamine has been researched along with Autism in 9 studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Research Excerpts

ExcerptRelevanceReference
"Strain genome comparisons identified autism candidate genes, including Cntnap2 and Slc6a4, located within regions divergent in C58/J."5.40Repetitive behavior profile and supersensitivity to amphetamine in the C58/J mouse model of autism. ( Agster, KL; Baker, LK; Bodfish, JW; Moy, SS; Nadler, JJ; Nikolova, VD; Nonneman, RJ; Riddick, NV; Teng, BL; Young, NB, 2014)
"Strain genome comparisons identified autism candidate genes, including Cntnap2 and Slc6a4, located within regions divergent in C58/J."1.40Repetitive behavior profile and supersensitivity to amphetamine in the C58/J mouse model of autism. ( Agster, KL; Baker, LK; Bodfish, JW; Moy, SS; Nadler, JJ; Nikolova, VD; Nonneman, RJ; Riddick, NV; Teng, BL; Young, NB, 2014)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19906 (66.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moy, SS1
Riddick, NV1
Nikolova, VD1
Teng, BL1
Agster, KL1
Nonneman, RJ1
Young, NB1
Baker, LK1
Nadler, JJ1
Bodfish, JW1
Braida, D1
Guerini, FR1
Ponzoni, L1
Corradini, I1
De Astis, S1
Pattini, L1
Bolognesi, E1
Benfante, R1
Fornasari, D1
Chiappedi, M1
Ghezzo, A1
Clerici, M1
Matteoli, M1
Sala, M1
Batinić, B1
Santrač, A1
Divović, B1
Timić, T1
Stanković, T1
Obradović, ALj1
Joksimović, S1
Savić, MM1
Bakwin, H1
Ridley, RM1
Baker, HF1
Kinsbourne, M1
Ginestet, D1
Bender, L1
Kornetsky, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Development and Validation of a System for the Anticipation of Challenging Behaviors of People With Autism Spectrum Disorder Based on a Smart Shirt: a Mixed-method Design[NCT05340608]51 participants (Actual)Observational2022-06-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for amphetamine and Autism

ArticleYear
Is there a relationship between social isolation, cognitive inflexibility, and behavioral stereotypy? An analysis of the effects of amphetamine in the marmoset.
    Progress in clinical and biological research, 1983, Volume: 131

    Topics: Amphetamine; Animals; Autistic Disorder; Brain; Callithrix; Choice Behavior; Cognition; Discriminati

1983
Psychoactive drugs in the immature organism.
    Psychopharmacologia, 1970, Volume: 17, Issue:2

    Topics: Amphetamine; Animals; Autistic Disorder; Behavior, Animal; Catecholamines; Child; Child Behavior; Ch

1970

Trials

1 trial available for amphetamine and Autism

ArticleYear
Psychoactive drugs in the immature organism.
    Psychopharmacologia, 1970, Volume: 17, Issue:2

    Topics: Amphetamine; Animals; Autistic Disorder; Behavior, Animal; Catecholamines; Child; Child Behavior; Ch

1970

Other Studies

7 other studies available for amphetamine and Autism

ArticleYear
Repetitive behavior profile and supersensitivity to amphetamine in the C58/J mouse model of autism.
    Behavioural brain research, 2014, Feb-01, Volume: 259

    Topics: Amphetamine; Animals; Autistic Disorder; Disease Models, Animal; Dizocilpine Maleate; Excitatory Ami

2014
Association between SNAP-25 gene polymorphisms and cognition in autism: functional consequences and potential therapeutic strategies.
    Translational psychiatry, 2015, Jan-27, Volume: 5

    Topics: Adolescent; Amphetamine; Animals; Autistic Disorder; Behavior, Animal; Central Nervous System Stimul

2015
Lipopolysaccharide exposure during late embryogenesis results in diminished locomotor activity and amphetamine response in females and spatial cognition impairment in males in adult, but not adolescent rat offspring.
    Behavioural brain research, 2016, Feb-15, Volume: 299

    Topics: Amphetamine; Animals; Autistic Disorder; Behavior, Animal; Cognition; Disease Models, Animal; Female

2016
Developmental hyperactivity.
    Acta paediatrica Scandinavica, 1967

    Topics: Adolescent; Amphetamine; Autistic Disorder; Child; Child Behavior Disorders; Child Guidance; Chlorpr

1967
Do repetitive movement patterns in children and animals serve a dearousing function?
    Journal of developmental and behavioral pediatrics : JDBP, 1980, Volume: 1, Issue:1

    Topics: Amphetamine; Animals; Arousal; Autistic Disorder; Displacement, Psychological; Humans; Intellectual

1980
The psychiatrist attitudes and therapeutic means when faced with resistant depressions.
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1974, Volume: 7, Issue:4

    Topics: Amitriptyline; Amphetamine; Antidepressive Agents; Autistic Disorder; Depression; Drug Resistance; D

1974
The life course of children with schizophrenia.
    The American journal of psychiatry, 1973, Volume: 130, Issue:7

    Topics: Amphetamine; Anticonvulsants; Autistic Disorder; Barbiturates; Child; Child, Preschool; Culture; Fam

1973