Page last updated: 2024-10-25

amphetamine and Atrophy

amphetamine has been researched along with Atrophy in 8 studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

ExcerptRelevanceReference
"The influence of embryonic mesencephalic, striatal and mesencephalic/striatal co-grafts on amphetamine- and apomorphine-induced rotation behaviour was assessed in a rat model of multiple system atrophy/striatonigral degeneration type using dopamine D1 ([3H]SCH23390) and D2 ([3H]spiperone) receptor and dopamine re-uptake ([3H]mazindol) autoradiography."7.70Autoradiographic study of striatal dopamine re-uptake sites and dopamine D1 and D2 receptors in a 6-hydroxydopamine and quinolinic acid double-lesion rat model of striatonigral degeneration (multiple system atrophy) and effects of embryonic ventral mesenc ( Granata, R; Jenner, P; Laboyrie, P; Poewe, W; Puschban, Z; Quinn, NP; Scherfler, C; Wenning, GK, 2000)
"The influence of embryonic mesencephalic, striatal and mesencephalic/striatal co-grafts on amphetamine- and apomorphine-induced rotation behaviour was assessed in a rat model of multiple system atrophy/striatonigral degeneration type using dopamine D1 ([3H]SCH23390) and D2 ([3H]spiperone) receptor and dopamine re-uptake ([3H]mazindol) autoradiography."3.70Autoradiographic study of striatal dopamine re-uptake sites and dopamine D1 and D2 receptors in a 6-hydroxydopamine and quinolinic acid double-lesion rat model of striatonigral degeneration (multiple system atrophy) and effects of embryonic ventral mesenc ( Granata, R; Jenner, P; Laboyrie, P; Poewe, W; Puschban, Z; Quinn, NP; Scherfler, C; Wenning, GK, 2000)
"One hundred ten patients with alcohol dependence and 56 psychiatric patients with either senile dementia, amphetamine psychosis, epilepsy or chronic schizophrenia were investigated with a CT scan of the brain."3.68Computerized tomographic study on the brain of patients with alcohol dependence. ( Kato, A; Nakajima, T; Nakamura, M; Tsuji, M, 1991)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's4 (50.00)18.2507
2000's2 (25.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Muhammad, A1
Kolb, B1
Bazzett, TJ1
Becker, JB1
Kaatz, KW1
Albin, RL1
Rosenblad, C1
Kirik, D1
Devaux, B1
Moffat, B1
Phillips, HS1
Björklund, A1
Freire-Garabal, M1
Núñez, MJ1
Balboa, J1
Rodríguez-Cobo, A1
López-Paz, JM1
Rey-Méndez, M1
Suárez-Quintanilla, JA1
Millán, JC1
Mayán, JM1
Puschban, Z1
Scherfler, C1
Granata, R1
Laboyrie, P1
Quinn, NP1
Jenner, P1
Poewe, W1
Wenning, GK1
Roghani, M1
Behzadi, G1
Kato, A1
Tsuji, M1
Nakamura, M1
Nakajima, T1
Stern, WC1
Hartmann, EL1

Other Studies

8 other studies available for amphetamine and Atrophy

ArticleYear
Maternal separation altered behavior and neuronal spine density without influencing amphetamine sensitization.
    Behavioural brain research, 2011, Sep-30, Volume: 223, Issue:1

    Topics: Amphetamine; Animals; Atrophy; Brain; Dendritic Spines; Disease Models, Animal; Female; Frontal Lobe

2011
Chronic intrastriatal dialytic administration of quinolinic acid produces selective neural degeneration.
    Experimental neurology, 1993, Volume: 120, Issue:2

    Topics: Amphetamine; Animals; Atrophy; Corpus Striatum; Dialysis; Dose-Response Relationship, Drug; Electron

1993
Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the lateral ventricle.
    The European journal of neuroscience, 1999, Volume: 11, Issue:5

    Topics: Amphetamine; Animals; Antibodies; Apomorphine; Atrophy; Body Weight; Cerebral Ventricles; Corpus Str

1999
Effects of amphetamine on development of oral candidiasis in rats.
    Clinical and diagnostic laboratory immunology, 1999, Volume: 6, Issue:4

    Topics: Amphetamine; Animals; Atrophy; Candida albicans; Candidiasis, Oral; Colony Count, Microbial; Male; M

1999
Autoradiographic study of striatal dopamine re-uptake sites and dopamine D1 and D2 receptors in a 6-hydroxydopamine and quinolinic acid double-lesion rat model of striatonigral degeneration (multiple system atrophy) and effects of embryonic ventral mesenc
    Neuroscience, 2000, Volume: 95, Issue:2

    Topics: Amphetamine; Animals; Apomorphine; Atrophy; Autoradiography; Behavior, Animal; Brain Tissue Transpla

2000
Neuroprotective effect of vitamin E on the early model of Parkinson's disease in rat: behavioral and histochemical evidence.
    Brain research, 2001, Feb-16, Volume: 892, Issue:1

    Topics: Amphetamine; Animals; Apomorphine; Atrophy; Axonal Transport; Corpus Striatum; Disease Models, Anima

2001
Computerized tomographic study on the brain of patients with alcohol dependence.
    The Japanese journal of psychiatry and neurology, 1991, Volume: 45, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Withdrawal Delirium; Alcoholism; Amphetamine; Atrophy; Brain

1991
Reduced amphetamine lethality following chronic stress.
    Psychopharmacologia, 1972, Volume: 23, Issue:2

    Topics: Adrenal Glands; Adrenocortical Hyperfunction; Amphetamine; Animals; Atrophy; Hypertrophy; Immersion;

1972