amphetamine has been researched along with Ataxia in 19 studies
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to evaluate the effect of subchronic caffeine treatment on MK-801-induced hyperlocomotion, ataxia and cognitive deficits, as well as amphetamine-induced hyperlocomotion in mice." | 7.73 | Effect of subchronic caffeine treatment on MK-801-induced changes in locomotion, cognition and ataxia in mice. ( Dall'Igna, OP; de Oliveira, RV; Lara, DR; Neto, PF; Santos Gomes, MW; Schuh, JF; Souza, DO; Tort, AB, 2005) |
| "Behavioral rating scales, developed to measure phencyclidine (PCP)-induced stereotypy and ataxia in rats, were tested using acute dose-response and chronic paradigms with concomitant assessment of locomotor activity by automated counters." | 7.66 | Acute and chronic phencyclidine effects on locomotor activity, stereotypy and ataxia in rats. ( Adams, PM; Castellani, S, 1981) |
| " The aim of this study was to evaluate the effect of subchronic caffeine treatment on MK-801-induced hyperlocomotion, ataxia and cognitive deficits, as well as amphetamine-induced hyperlocomotion in mice." | 3.73 | Effect of subchronic caffeine treatment on MK-801-induced changes in locomotion, cognition and ataxia in mice. ( Dall'Igna, OP; de Oliveira, RV; Lara, DR; Neto, PF; Santos Gomes, MW; Schuh, JF; Souza, DO; Tort, AB, 2005) |
| "Behavioral rating scales, developed to measure phencyclidine (PCP)-induced stereotypy and ataxia in rats, were tested using acute dose-response and chronic paradigms with concomitant assessment of locomotor activity by automated counters." | 3.66 | Acute and chronic phencyclidine effects on locomotor activity, stereotypy and ataxia in rats. ( Adams, PM; Castellani, S, 1981) |
| "Dose/response relations have been analysed for the actions of amphetamine-barbiturate mixtures on exploratory activity and ataxia in rats." | 3.64 | MUTUAL POTENTIATION OF AMPHETAMINE AND AMYLOBARBITONE MEASURED BY ACTIVITY IN RATS. ( RUSHTON, R; STEINBERG, H, 1963) |
| "Animal models of Parkinson's disease have been widely used for investigating the mechanisms of neurodegenerative process and for discovering alternative strategies for treating the disease." | 1.35 | Restorative effect of endurance exercise on behavioral deficits in the chronic mouse model of Parkinson's disease with severe neurodegeneration. ( Kurz, MJ; Lau, YS; Pothakos, K, 2009) |
| "Locomotor activity, ataxia, and stereotypy were assessed in the open field after administration of NMDA and AMPA antagonists acting by different mechanisms." | 1.29 | Glutamate antagonists have different effects on spontaneous locomotor activity in rats. ( Bresink, I; Danysz, W; Essmann, U; Wilke, R, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (63.16) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davoren, JE | 1 |
| Garnsey, M | 1 |
| Pettersen, B | 1 |
| Brodney, MA | 1 |
| Edgerton, JR | 1 |
| Fortin, JP | 1 |
| Grimwood, S | 1 |
| Harris, AR | 1 |
| Jenkinson, S | 1 |
| Kenakin, T | 1 |
| Lazzaro, JT | 1 |
| Lee, CW | 1 |
| Lotarski, SM | 1 |
| Nottebaum, L | 1 |
| O'Neil, SV | 1 |
| Popiolek, M | 1 |
| Ramsey, S | 1 |
| Steyn, SJ | 1 |
| Thorn, CA | 1 |
| Zhang, L | 1 |
| Webb, D | 1 |
| Lai, CC | 1 |
| Lee, LJ | 1 |
| Yin, HS | 1 |
| Pothakos, K | 1 |
| Kurz, MJ | 1 |
| Lau, YS | 1 |
| Bamitale, KD | 1 |
| Akanmu, MA | 1 |
| Ukponmwan, OE | 1 |
| EYSENCK, HJ | 1 |
| EASTERBROOK, JA | 1 |
| RUSHTON, R | 1 |
| STEINBERG, H | 1 |
| de Oliveira, RV | 1 |
| Dall'Igna, OP | 1 |
| Tort, AB | 1 |
| Schuh, JF | 1 |
| Neto, PF | 1 |
| Santos Gomes, MW | 1 |
| Souza, DO | 1 |
| Lara, DR | 1 |
| Latz, A | 1 |
| Bain, G | 1 |
| Goldman, M | 1 |
| Kornetsky, C | 1 |
| DeMichele, G | 1 |
| Jolicoeur, FB | 1 |
| Rondeau, DB | 1 |
| Butterworth, RF | 1 |
| Barbeau, A | 1 |
| Castellani, S | 1 |
| Adams, PM | 1 |
| Draski, LJ | 1 |
| Nash, DJ | 1 |
| Gerhardt, GA | 1 |
| Danysz, W | 1 |
| Essmann, U | 1 |
| Bresink, I | 1 |
| Wilke, R | 1 |
| Trulson, ME | 1 |
| Jacobs, BL | 1 |
| Contreras, PC | 1 |
| Johnson, S | 1 |
| Freedman, R | 1 |
| Hoffer, B | 1 |
| Olsen, K | 1 |
| Rafferty, MF | 1 |
| Lessor, RA | 1 |
| Rice, KC | 1 |
| Jacobson, AE | 1 |
| O'Donohue, TL | 1 |
| Glogner, P | 1 |
| Alhava, E | 1 |
| Grunfeld, Y | 1 |
| Edery, H | 1 |
| Pálosi, E | 1 |
| Mészáros, C | 1 |
| Szporny, L | 1 |
| Schneider, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Impact of Caffeine on Cognition in Schizophrenia[NCT02832401] | 24 participants (Actual) | Interventional | 2016-09-02 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
19 other studies available for amphetamine and Ataxia
| Article | Year |
|---|---|
Design and Synthesis of γ- and δ-Lactam M
Topics: Allosteric Regulation; Amphetamine; Animals; Ataxia; Diarrhea; Dogs; Donepezil; Drug Design; Female; | 2017 |
Combinational effects of ketamine and amphetamine on behaviors and neurotransmitter systems of mice.
Topics: Amphetamine; Animals; Ataxia; Behavior, Animal; Brain; Central Nervous System Stimulants; Dopamine; | 2013 |
Restorative effect of endurance exercise on behavioral deficits in the chronic mouse model of Parkinson's disease with severe neurodegeneration.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Animals; Ataxia; Disease Models, Animal; | 2009 |
Neuropharmacological profile of aqueous extract of Anaphe venata larva (Notondotidae) in rats.
Topics: Amphetamine; Animals; Ataxia; Behavior, Animal; Dose-Response Relationship, Drug; Flumazenil; Groomi | 2011 |
Drugs and personality. VI. The effects of stimulant and depressant drugs upon body sway (static ataxia).
Topics: Amobarbital; Amphetamine; Amphetamines; Ataxia; Central Nervous System Stimulants; Humans; Meprobama | 1960 |
MUTUAL POTENTIATION OF AMPHETAMINE AND AMYLOBARBITONE MEASURED BY ACTIVITY IN RATS.
Topics: Amobarbital; Amphetamine; Animals; Ataxia; Behavior, Animal; Dextroamphetamine; Motivation; Pharmaco | 1963 |
Effect of subchronic caffeine treatment on MK-801-induced changes in locomotion, cognition and ataxia in mice.
Topics: Adenosine; Amphetamine; Animals; Ataxia; Caffeine; Central Nervous System Stimulants; Cognition; Dis | 2005 |
Maze learning after the administration of antidepressant drugs.
Topics: Amphetamine; Animals; Antidepressive Agents; Ataxia; Behavior, Animal; Body Temperature Regulation; | 1967 |
Effects of glutamate and aspartate on ataxic gait induced by 3-acetyl pyridine in rats.
Topics: Amphetamine; Animals; Apomorphine; Aspartic Acid; Ataxia; Gait; Glutamates; Male; Pyridines; Rats; S | 1980 |
Acute and chronic phencyclidine effects on locomotor activity, stereotypy and ataxia in rats.
Topics: Amphetamine; Analysis of Variance; Animals; Apomorphine; Ataxia; Dose-Response Relationship, Drug; H | 1981 |
CNS monoamine levels and motoric behaviors in the hotfoot ataxic mutant.
Topics: Aging; Amphetamine; Animals; Ataxia; Biogenic Monoamines; Body Temperature; Body Weight; Central Ner | 1994 |
Glutamate antagonists have different effects on spontaneous locomotor activity in rats.
Topics: Amphetamine; Animals; Ataxia; Binding, Competitive; Dizocilpine Maleate; Excitatory Amino Acid Antag | 1994 |
LSD acts synergistically with serotonin depletion: evidence from behavioral studies in cats.
Topics: Amphetamine; Animals; Ataxia; Behavior, Animal; Cats; Drug Synergism; Female; Fenclonine; Grooming; | 1976 |
Metaphit, an acylating ligand for phencyclidine receptors: characterization of in vivo actions in the rat.
Topics: Acylation; Amphetamine; Animals; Ataxia; Caudate Nucleus; Dose-Response Relationship, Drug; Injectio | 1986 |
[Unfavorable and problematic drug combinations. IV].
Topics: Amphetamine; Ataxia; Bone Marrow; Cerebral Hemorrhage; Depression, Chemical; Dicumarol; Dihydroxyphe | 1970 |
Amphetamine toxicity in adult and developing mice.
Topics: Age Factors; Amphetamine; Animals; Ataxia; Body Surface Area; Central Nervous System; Drug Tolerance | 1972 |
Psychopharmacological activity of the active constituents of hashish and some related cannabinoids.
Topics: Alkaloids; Amphetamine; Animals; Ataxia; Avoidance Learning; Behavior, Animal; Benzopyrans; Cannabis | 1969 |
Pharmacological studies with N-3,4,5-trimethoxybenzoyl-heptamethylene imine (N-1157), a new antidepressant agent.
Topics: Amphetamine; Animals; Antidepressive Agents; Ataxia; Blood Pressure; Body Temperature; Catalepsy; Ca | 1969 |
Behavioural effects of some morphine antagonists and hallucinogens in the rat.
Topics: Amphetamine; Analgesics; Anesthetics; Animals; Ataxia; Atropine; Azocines; Behavior, Animal; Cyclazo | 1968 |