amphetamine has been researched along with Anorexia in 28 studies
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
Anorexia: The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Imipramine and mianserine potentiated amphetamine-induced anorexia both after acute administration or after prolonged previous treatment with each drug." | 7.68 | Lack of tolerance to imipramine or mianserine in two animal models of depression. ( Barros, HM; Tannhauser, M; Wainstein, M, 1990) |
| "The concept of dopamine receptor subtypes and the recent development of selective dopamine receptor agonists and antagonists raises the possibility of specific subtype involvement in amphetamine-induced anorexia, and, furthermore, provides the means to evaluate the possibility." | 7.67 | Analysis of dopamine D1 and D2 receptor involvement in d- and l-amphetamine-induced anorexia in rats. ( Cooper, SJ; Gilbert, DB, 1985) |
| "Repeated treatment with amphetamine (AMPH), an anorectic agent, induced a marked anorexia on day 1 followed by a gradual reversion of this anorexia to the normal level of feeding (tolerant anorexia)." | 3.71 | Role of cerebral dopamine but not plasma insulin, leptin and glucocorticoid in the development of tolerance to the anorectic effect of amphetamine. ( Cheng, JT; Kuo, DY, 2002) |
| "5 mg/kg amphetamine and 75 microM/kg LiCl, which produced similar degrees of anorexia, inhibited running by about 50%." | 3.68 | Scheduled running wheel activity indexes the specificity of pharmacological anorexia. ( Fudge, J; Geary, N; Le Sauter, J, 1992) |
| " Imipramine and mianserine potentiated amphetamine-induced anorexia both after acute administration or after prolonged previous treatment with each drug." | 3.68 | Lack of tolerance to imipramine or mianserine in two animal models of depression. ( Barros, HM; Tannhauser, M; Wainstein, M, 1990) |
| "The effect of 6-OHDA-induced lesions of neostriatum on locomotor activity, stereotypy and anorexia induced by amphetamine (0." | 3.67 | Dissociable effects of 6-OHDA-induced lesions of neostriatum on anorexia, locomotor activity and stereotypy: the role of behavioural competition. ( Iversen, SD; Joyce, EM, 1984) |
| "The concept of dopamine receptor subtypes and the recent development of selective dopamine receptor agonists and antagonists raises the possibility of specific subtype involvement in amphetamine-induced anorexia, and, furthermore, provides the means to evaluate the possibility." | 3.67 | Analysis of dopamine D1 and D2 receptor involvement in d- and l-amphetamine-induced anorexia in rats. ( Cooper, SJ; Gilbert, DB, 1985) |
| "Development of a contingent tolerance to amphetamine (AMPH) anorexia has been reported with chronic s." | 3.67 | Dissociation of receptor sensitivity changes in rat perifornical hypothalamus: a role for dopaminergic receptors in amphetamine anorexic tolerance. ( Bhakthavatsalam, P; Ghosh, MN; Kamatchi, GL, 1987) |
| " Among the hallucinogens decreasing food intake, both LSD and atropine produced substantial anorexia, but the slopes of their dose-response curves were clearly different from d-amphetamine." | 3.66 | Anorexia and hyperphagia produced by five pharmacologic classes of hallucinogens. ( Morton, EC; Vaupel, DB, 1982) |
| " Complete dose-response functions for the effects of the drugs on food pellet intake on days that candy was not available were determined before, during, and after the period of access to candy." | 1.37 | Consumption of palatable food decreases the anorectic effects of serotonergic, but not dopaminergic drugs in baboons. ( Foltin, RW, 2011) |
| "AMPH-induced anorexia is documented to mediate through the release of dopamine (DA), via an activation of D(1)- and D(2)-subtype receptors, to affect the hypothalamic NPY." | 1.31 | Effect of amphetamine repeated treatment on the feeding behavior in neuropeptide Y-overexpressing mice. ( Cheng, JT; Inui, A; Kuo, DY, 2002) |
| " These results suggest that MET is endowed with peculiar hypophagic effects at dosage levels that are not able to affect gross behaviour in mice." | 1.31 | Methylamine and benzylamine induced hypophagia in mice: modulation by semicarbazide-sensitive benzylamine oxidase inhibitors and aODN towards Kv1.1 channels. ( Banchelli, G; Galeotti, N; Ghelardini, C; Pirisino, R; Raimondi, L, 2001) |
| "Amphetamine-treated rats developed tolerance to these ingestive effects and to weight loss, whereas nicotine-injected rats did not." | 1.26 | Nicotine and amphetamine: differential tolerance and no cross-tolerance for ingestive effects. ( Baettig, K; Classen, W; Martin, JR, 1980) |
| "Clonidine was 100 times more potent than norepinephrine and increased the intake of both the ordinary diet of powdered food and a highly palatable wet food." | 1.25 | Neurochemical regulation of feeding in the rat: facilitation by alpha-noradrenergic, but not dopaminergic, receptor stimulants. ( Ritter, S; Stein, L; Wise, D, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (42.86) | 18.7374 |
| 1990's | 6 (21.43) | 18.2507 |
| 2000's | 4 (14.29) | 29.6817 |
| 2010's | 6 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| White, W | 1 |
| Beyer, JD | 1 |
| White, IM | 1 |
| Hsieh, YS | 2 |
| Yang, SF | 2 |
| Chen, PN | 1 |
| Chu, SC | 1 |
| Chen, CH | 1 |
| Kuo, DY | 4 |
| Foltin, RW | 1 |
| Wolgin, DL | 2 |
| Jean, A | 1 |
| Laurent, L | 1 |
| Bockaert, J | 1 |
| Charnay, Y | 1 |
| Dusticier, N | 1 |
| Nieoullon, A | 1 |
| Barrot, M | 1 |
| Neve, R | 1 |
| Compan, V | 1 |
| Inui, A | 1 |
| Cheng, JT | 2 |
| LONGO, VG | 1 |
| DI FERRENTE, N | 1 |
| CUCURACHI, L | 1 |
| SALVI, G | 1 |
| STRATA, A | 1 |
| SIMKIN, B | 1 |
| WALLACE, L | 1 |
| Vaupel, DB | 1 |
| Morton, EC | 1 |
| Silverstone, T | 1 |
| Joyce, EM | 1 |
| Iversen, SD | 1 |
| Leshem, M | 1 |
| Baettig, K | 1 |
| Martin, JR | 1 |
| Classen, W | 1 |
| Gitanjali, B | 1 |
| Sivagnanam, G | 1 |
| Raveendran, R | 1 |
| Shashindran, CH | 1 |
| Gillard, ER | 1 |
| Dang, DQ | 1 |
| Stanley, BG | 1 |
| Pirisino, R | 1 |
| Ghelardini, C | 1 |
| Banchelli, G | 1 |
| Galeotti, N | 1 |
| Raimondi, L | 1 |
| Ritter, S | 1 |
| Wise, D | 1 |
| Stein, L | 1 |
| Clark, JM | 1 |
| Clark, AJ | 1 |
| Winn, P | 1 |
| Geary, N | 1 |
| Fudge, J | 1 |
| Le Sauter, J | 1 |
| Parada, MA | 1 |
| Hernández, L | 1 |
| Degoma, E | 1 |
| Wainstein, M | 1 |
| Tannhauser, M | 1 |
| Barros, HM | 1 |
| Gilbert, DB | 1 |
| Cooper, SJ | 1 |
| Oslan, IA | 1 |
| Thompson, GB | 1 |
| Bhakthavatsalam, P | 1 |
| Kamatchi, GL | 1 |
| Ghosh, MN | 1 |
3 reviews available for amphetamine and Anorexia
| Article | Year |
|---|---|
Racemic amphetamine sulfate (Evekeo) for ADHD.
Topics: Amphetamine; Animals; Anorexia; Attention Deficit Disorder with Hyperactivity; Child; Humans; Random | 2015 |
Amphetamine stereotypy, the basal ganglia, and the "selection problem".
Topics: Amphetamine; Animals; Anorexia; Appetitive Behavior; Basal Ganglia; Central Nervous System Stimulant | 2012 |
The clinical pharmacology of appetite--its relevance to psychiatry.
Topics: Amphetamine; Anorexia; Appetite; Bipolar Disorder; Brain Chemistry; Depressive Disorder; Dopamine; F | 1983 |
25 other studies available for amphetamine and Anorexia
| Article | Year |
|---|---|
Acute withdrawal-related hypophagia elicited by amphetamine is attenuated by pretreatment with selective dopamine D1 or D2 receptor antagonists in rats.
Topics: Amphetamine; Analysis of Variance; Animals; Anorexia; Benzazepines; Central Nervous System Stimulant | 2015 |
Knocking down the transcript of protein kinase C-lambda modulates hypothalamic glutathione peroxidase, melanocortin receptor and neuropeptide Y gene expression in amphetamine-treated rats.
Topics: alpha-Methyltyrosine; Amphetamine; Animals; Anorexia; Antisense Elements (Genetics); Appetite Depres | 2011 |
Consumption of palatable food decreases the anorectic effects of serotonergic, but not dopaminergic drugs in baboons.
Topics: Amphetamine; Animals; Anorexia; Dexfenfluramine; Dietary Sucrose; Disease Models, Animal; Dopamine U | 2011 |
The nucleus accumbens 5-HTRâ‚„-CART pathway ties anorexia to hyperactivity.
Topics: Amphetamine; Animals; Anorexia; Cocaine; Hyperkinesis; Male; Mice; Mice, Knockout; N-Methyl-3,4-meth | 2012 |
Effect of amphetamine repeated treatment on the feeding behavior in neuropeptide Y-overexpressing mice.
Topics: Amphetamine; Animals; Anorexia; Central Nervous System Stimulants; Dopamine Antagonists; Dopamine D2 | 2002 |
Role of cerebral dopamine but not plasma insulin, leptin and glucocorticoid in the development of tolerance to the anorectic effect of amphetamine.
Topics: Adrenalectomy; alpha-Methyltyrosine; Amphetamine; Animals; Anorexia; Brain; Catecholamines; Dopamine | 2002 |
[The effect of prefrontal lobotomy of the anorexic action of benzedrine].
Topics: Amphetamine; Amphetamines; Anorexia; Frontal Lobe; Humans; Psychosurgery | 1952 |
[METABOLIC COMPONENT IN MECHANISM OF ANOREXIC ACTION OF AMPHETAMINES].
Topics: Amphetamine; Amphetamines; Anorexia; Biochemical Phenomena; Humans; Pharmacology | 1964 |
Some quantitative observations on a methamphetamine-phenobarbital anorexic compound in obese outpatients.
Topics: Amphetamine; Amphetamines; Anorexia; Methamphetamine; Obesity; Outpatients; Phenobarbital | 1960 |
Intracerebral administration of protein kinase A or cAMP response element-binding protein antisense oligonucleotide can modulate amphetamine-mediated appetite suppression in free-moving rats.
Topics: Amphetamine; Animals; Anorexia; Appetite Depressants; Appetite Regulation; Cyclic AMP Response Eleme | 2007 |
Anorexia and hyperphagia produced by five pharmacologic classes of hallucinogens.
Topics: Amphetamine; Animals; Anorexia; Atropine; Dextroamphetamine; Dogs; Dronabinol; Feeding and Eating Di | 1982 |
Dissociable effects of 6-OHDA-induced lesions of neostriatum on anorexia, locomotor activity and stereotypy: the role of behavioural competition.
Topics: Amphetamine; Animals; Anorexia; Catecholamines; Corpus Striatum; Feeding and Eating Disorders; Feedi | 1984 |
Morphine-induced anorexia in lateral hypothalamic rats.
Topics: Amphetamine; Animals; Anorexia; Dextroamphetamine; Feeding and Eating Disorders; Fenfluramine; Human | 1981 |
Nicotine and amphetamine: differential tolerance and no cross-tolerance for ingestive effects.
Topics: Amphetamine; Animals; Anorexia; Body Weight; Drug Tolerance; Eating; Male; Nicotine; Rats | 1980 |
Ascorbic acid delays the development of tolerance to amphetamine induced anorexia but does not affect the reverse tolerance which develops to the locomotor activity.
Topics: Amphetamine; Animals; Anorexia; Ascorbic Acid; Drug Tolerance; Male; Motor Activity; Rats; Rats, Wis | 1994 |
Evidence that neuropeptide Y and dopamine in the perifornical hypothalamus interact antagonistically in the control of food intake.
Topics: Amphetamine; Animals; Anorexia; Catecholamines; Dopamine; Eating; Epinephrine; Hypothalamus; Male; N | 1993 |
Methylamine and benzylamine induced hypophagia in mice: modulation by semicarbazide-sensitive benzylamine oxidase inhibitors and aODN towards Kv1.1 channels.
Topics: Allyl Compounds; Ammonium Chloride; Amphetamine; Animals; Anorexia; Behavior, Animal; Benzylamine Ox | 2001 |
Neurochemical regulation of feeding in the rat: facilitation by alpha-noradrenergic, but not dopaminergic, receptor stimulants.
Topics: Adrenergic alpha-Agonists; Amphetamine; Animals; Anorexia; Apomorphine; Cerebral Ventricles; Chemore | 1975 |
N-methyl-D-aspartate lesions of the lateral hypothalamus do not reduce amphetamine or fenfluramine anorexia but enhance the acquisition of eating in response to tail pinch in the rat.
Topics: Amphetamine; Analysis of Variance; Animals; Anorexia; Feeding Behavior; Fenfluramine; Hypothalamic A | 1992 |
Scheduled running wheel activity indexes the specificity of pharmacological anorexia.
Topics: Amphetamine; Animals; Anorexia; Behavior, Animal; Feeding Behavior; Female; Injections, Intraperiton | 1992 |
Serotonin may play a role in the anorexia induced by amphetamine injections into the lateral hypothalamus.
Topics: Amphetamine; Animals; Anorexia; Epinephrine; Hypothalamic Area, Lateral; Injections; Male; Norepinep | 1992 |
Lack of tolerance to imipramine or mianserine in two animal models of depression.
Topics: Amphetamine; Animals; Anorexia; Behavior, Animal; Depression; Disease Models, Animal; Dose-Response | 1990 |
Analysis of dopamine D1 and D2 receptor involvement in d- and l-amphetamine-induced anorexia in rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Anorexia; Appetite | 1985 |
Effects of "anorexia" on appetitive and consummatory behavior.
Topics: Amphetamine; Animals; Anorexia; Appetite; Feeding and Eating Disorders; Feeding Behavior; Fenflurami | 1988 |
Dissociation of receptor sensitivity changes in rat perifornical hypothalamus: a role for dopaminergic receptors in amphetamine anorexic tolerance.
Topics: Amphetamine; Animals; Anorexia; Benserazide; Dextroamphetamine; Drug Tolerance; Eating; Feeding and | 1987 |