Page last updated: 2024-10-25

amphetamine and Anhedonia

amphetamine has been researched along with Anhedonia in 8 studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Anhedonia: Inability to experience pleasure due to impairment or dysfunction of normal psychological and neurobiological mechanisms. It is a symptom of many PSYCHOTIC DISORDERS (e.g., DEPRESSIVE DISORDER, MAJOR; and SCHIZOPHRENIA).

Research Excerpts

ExcerptRelevanceReference
"Asenapine is indicated for the treatment of schizophrenia and manic episodes in bipolar disorder (BPD)."3.81The effects of the atypical antipsychotic asenapine in a strain-specific battery of tests for mania-like behaviors. ( Einat, H; Ene, HM; Kara, NZ, 2015)
"These findings may direct future treatment of anhedonia by targeting DA and glucocorticoid systems, as well as a possible interaction between the two."1.48Investigating dopamine and glucocorticoid systems as underlying mechanisms of anhedonia. ( Lamontagne, SJ; Melendez, SI; Olmstead, MC, 2018)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (87.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Kangas, BD1
Wooldridge, LM1
Luc, OT1
Bergman, J1
Pizzagalli, DA1
Spierling, SR1
Mattock, M1
Zorrilla, EP1
Pappas, AL1
Bey, AL1
Wang, X1
Rossi, M1
Kim, YH1
Yan, H1
Porkka, F1
Duffney, LJ1
Phillips, SM1
Cao, X1
Ding, JD1
Rodriguiz, RM1
Yin, HH1
Weinberg, RJ1
Ji, RR1
Wetsel, WC1
Jiang, YH1
Lamontagne, SJ1
Melendez, SI1
Olmstead, MC1
Giovanoli, S1
Werge, TM1
Mortensen, PB1
Didriksen, M1
Meyer, U1
Felger, JC1
Mun, J1
Kimmel, HL1
Nye, JA1
Drake, DF1
Hernandez, CR1
Freeman, AA1
Rye, DB1
Goodman, MM1
Howell, LL1
Miller, AH1
Ene, HM1
Kara, NZ1
Einat, H1
Miczek, KA1
Nikulina, EM1
Takahashi, A1
Covington, HE1
Yap, JJ1
Boyson, CO1
Shimamoto, A1
de Almeida, RM1

Reviews

1 review available for amphetamine and Anhedonia

ArticleYear
Gene expression in aminergic and peptidergic cells during aggression and defeat: relevance to violence, depression and drug abuse.
    Behavior genetics, 2011, Volume: 41, Issue:6

    Topics: Aggression; Amines; Amphetamine; Anhedonia; Animals; Brain; Brain Stem; Cocaine; Female; Gene Expres

2011

Other Studies

7 other studies available for amphetamine and Anhedonia

ArticleYear
Empirical validation of a touchscreen probabilistic reward task in rats.
    Translational psychiatry, 2020, 08-13, Volume: 10, Issue:1

    Topics: Amphetamine; Anhedonia; Animals; Depressive Disorder, Major; Female; Learning; Rats; Reward

2020
Modeling hypohedonia following repeated social defeat: Individual vulnerability and dopaminergic involvement.
    Physiology & behavior, 2017, Aug-01, Volume: 177

    Topics: Amphetamine; Anhedonia; Animals; Choice Behavior; Dominance-Subordination; Dopamine; Dopamine Uptake

2017
Deficiency of Shank2 causes mania-like behavior that responds to mood stabilizers.
    JCI insight, 2017, 10-19, Volume: 2, Issue:20

    Topics: Amphetamine; Anhedonia; Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Central Nervo

2017
Investigating dopamine and glucocorticoid systems as underlying mechanisms of anhedonia.
    Psychopharmacology, 2018, Volume: 235, Issue:11

    Topics: Amphetamine; Anhedonia; Animals; Dopamine; Dopamine Agents; Dopamine Agonists; Glucocorticoids; Lear

2018
Interactive effects between hemizygous 15q13.3 microdeletion and peripubertal stress on adult behavioral functions.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019, Volume: 44, Issue:4

    Topics: Age Factors; Amphetamine; Anhedonia; Animals; Anxiety; Behavior, Animal; Central Nervous System Stim

2019
Chronic interferon-α decreases dopamine 2 receptor binding and striatal dopamine release in association with anhedonia-like behavior in nonhuman primates.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:11

    Topics: Amphetamine; Anhedonia; Animals; Carbon Radioisotopes; Corpus Striatum; Dopamine; Dopamine Antagonis

2013
The effects of the atypical antipsychotic asenapine in a strain-specific battery of tests for mania-like behaviors.
    Behavioural pharmacology, 2015, Volume: 26, Issue:4

    Topics: Akathisia, Drug-Induced; Amphetamine; Anhedonia; Animals; Antimanic Agents; Antipsychotic Agents; Ap

2015