Page last updated: 2024-10-25

amphetamine and Anesthesia

amphetamine has been researched along with Anesthesia in 40 studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
" In cats, the effects of tranylcypromine and pheniprazine, two monoamine oxidase (MAO) inhibitors with strong amphetamine-like actions, of pargyline, an inhibitor without amphetamine-like actions, and of amphetamine itself, were examined on the hypothermia produced by a 2 hr period of halothane inhalation."7.65Effects of monoamine oxidase inhibitors and amphetamine on hypothermia produced by halothane. ( Feldberg, W; Lang, WJ, 1970)
" The primary objective of the current study was to assess differences in blood pressure and heart rate before and after induction of anesthesia between patients on chronic amphetamine or methylphenidate therapy who receive their normal dose preoperatively compared to patients in whom the prescribed medication was withheld."3.85Hemodynamic profile and behavioral characteristics during induction of anesthesia in pediatric patients with attention deficit hyperactivity disorder. ( Cartabuke, RS; Rice, J; Tobias, JD; Tumin, D, 2017)
" In cats, the effects of tranylcypromine and pheniprazine, two monoamine oxidase (MAO) inhibitors with strong amphetamine-like actions, of pargyline, an inhibitor without amphetamine-like actions, and of amphetamine itself, were examined on the hypothermia produced by a 2 hr period of halothane inhalation."3.65Effects of monoamine oxidase inhibitors and amphetamine on hypothermia produced by halothane. ( Feldberg, W; Lang, WJ, 1970)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199031 (77.50)18.7374
1990's2 (5.00)18.2507
2000's4 (10.00)29.6817
2010's3 (7.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kashiwagi, Y1
Rokugawa, T1
Yamada, T1
Obata, A1
Watabe, H1
Yoshioka, Y1
Abe, K1
Cartabuke, RS1
Tobias, JD1
Rice, J1
Tumin, D1
ABEL, S1
HARRIS, SC1
McCormick, PN1
Ginovart, N1
Wilson, AA1
VOORHOEVE, HC1
KADEN, W1
NIKIFOROV, MI1
SZENDEI, A1
DOBROVITS, T1
HERR, F1
ERDELYI, G1
KEREKES, E1
JACKSON, B1
HARRIS, LS1
UHLE, FC1
TAYLOR, RG1
DOKU, HC1
HANNA, C1
UPTON, PD1
CHAMBERS, WF1
PERKS, ER1
WOJEWODZKI, W1
EVERS, W1
MALIK, K1
DOBKIN, AB2
LEE, PK1
CHO, MH1
NORTON, J1
NICKERSON, M2
PLENK, AM1
Liles, JT1
Dabisch, PA1
Hude, KE1
Pradhan, L1
Varner, KJ1
Porter, JR1
Hicks, AR1
Corll, C1
Baber, SR1
Kadowitz, PJ1
Jongen, C1
de Bruin, K1
Beekman, F1
Booij, J1
Wright, M1
Cremades, A1
Serrano, JS1
Jané, F1
Milanés, MV1
Moroni, F1
Corradetti, R1
Casamenti, F2
Moneti, G1
Pepeu, G2
Bianchi, C1
Beani, L1
Fink-Jensen, A1
Ingwersen, SH1
Nielsen, PG1
Hansen, L1
Nielsen, EB1
Hansen, AJ1
Lin, MT1
Chuang, SF1
Li, YC1
Young, MS1
Chai, CY1
Berridge, CW1
Morris, MF1
Florence, G1
Bonnier, R1
Plagnes, D1
Piérard, C1
Satabin, P1
Pérès, M1
Lagarde, D1
Horita, A1
Carino, MA1
Nielsen, IM1
Boeck, V1
Christensen, AV1
Danneskiold-Samsoe, P1
Hyttel, J1
Langeland, J1
Pedersen, V1
Svendsen, O1
Bunney, BS1
Walters, JR1
Kuhar, MJ1
Roth, RH1
Aghajanian, GK1
Klissiunis, N1
Paradelis, A1
Stoichev, Ts1
Koleva, M1
Kirova, A1
Klemm, WR1
Feldberg, W1
Lang, WJ1
Bolt, AG1
Mulligan, BM1
Graham, G1
Hatch, RC1
Ruch, T1
Doberauer, W1
Buyniski, JP1
Smith, ML1
Bierwagen, ME1
Leake, CD1

Reviews

3 reviews available for amphetamine and Anesthesia

ArticleYear
MONOAMINE OXIDASE INHIBITORS.
    Anaesthesia, 1964, Volume: 19

    Topics: Amphetamine; Amphetamines; Anesthesia; Anesthetics; Antidepressive Agents; Chlorpromazine; Ephedrine

1964
Pharmacologic effects of ketamine and its use in veterinary medicine.
    Journal of the American Veterinary Medical Association, 1982, Jun-15, Volume: 180, Issue:12

    Topics: Amphetamine; Anesthesia; Animals; Antipsychotic Agents; Brain; Cardiovascular System; Cats; Cattle;

1982
Review of reviews.
    Annual review of pharmacology, 1970, Volume: 10

    Topics: Alcohols; Amphetamine; Anesthesia; Animals; Cardiovascular System; Drug Therapy; Hormones; Kidney; N

1970

Other Studies

37 other studies available for amphetamine and Anesthesia

ArticleYear
Pharmacological MRI response to a selective dopamine transporter inhibitor, GBR12909, in awake and anesthetized rats.
    Synapse (New York, N.Y.), 2015, Volume: 69, Issue:4

    Topics: Amphetamine; Anesthesia; Animals; Brain; Brain Mapping; Dopamine Agents; Dopamine Plasma Membrane Tr

2015
Hemodynamic profile and behavioral characteristics during induction of anesthesia in pediatric patients with attention deficit hyperactivity disorder.
    Paediatric anaesthesia, 2017, Volume: 27, Issue:4

    Topics: Adolescent; Amphetamine; Anesthesia; Anti-Anxiety Agents; Anxiety; Attention Deficit Disorder with H

2017
Morphine-benzedrine analgesia in obstetrics.
    Federation proceedings, 1947, Volume: 6, Issue:1 Pt 2

    Topics: Amphetamine; Analgesia; Anesthesia; Anesthesia, Obstetrical; Female; Gynecology; Humans; Morphine; O

1947
Isoflurane anaesthesia differentially affects the amphetamine sensitivity of agonist and antagonist D2/D3 positron emission tomography radiotracers: implications for in vivo imaging of dopamine release.
    Molecular imaging and biology, 2011, Volume: 13, Issue:4

    Topics: Amphetamine; Anesthesia; Animals; Cats; Cerebellum; Dopamine; Dopamine D2 Receptor Antagonists; Isof

2011
[Hiccup during and after anesthesia].
    Nederlands tijdschrift voor geneeskunde, 1954, Nov-13, Volume: 98, Issue:46

    Topics: Amphetamine; Amphetamines; Anesthesia; Anesthesiology; Hiccup; Humans

1954
[Experience with peridural anesthesia, with special consideration of blood pressure stabilizing adjuvants in the anesthetic solution].
    Zentralblatt fur Chirurgie, 1957, Jun-22, Volume: 82, Issue:25

    Topics: Amphetamine; Amphetamines; Anesthesia; Anesthesia, Epidural; Anesthesia, Spinal; Anesthetics; Blood

1957
[Effect of extirpation of the cerebral hemispheres in pigeons on manifestation of anti-narcotic action of corazole, phenamine and of their mixtures].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1957, Volume: 43, Issue:10

    Topics: Amphetamine; Amphetamines; Anesthesia; Anesthesiology; Animals; Brain; Cerebrum; Columbidae; Humans;

1957
[Effect of the aktedron-adrenalin synergism on the prolongation of local anesthesia procaine].
    Orvosi hetilap, 1958, Jul-20, Volume: 99, Issue:29

    Topics: Amphetamine; Amphetamines; Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Local; Epine

1958
Aspects of the induction of anaesthesia with thiopentone.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1958, Jul-19, Volume: 32, Issue:29

    Topics: Amphetamine; Amphetamines; Analgesia; Anesthesia; Anesthesia and Analgesia; Pain Management; Thiopen

1958
Enhancement of amphetamine stimulation and prolongation of barbiturate depression by a substituted pyridl 3,4-blindole derivative.
    The Journal of pharmacology and experimental therapeutics, 1961, Volume: 132

    Topics: Amphetamine; Amphetamines; Analgesia; Anesthesia; Anesthesia and Analgesia; Barbiturates; Depression

1961
USE OF A 'SOMA' COMPOUND IN PAIN CONTROL AFTER ORAL SURGERY.
    Journal of oral surgery, anesthesia, and hospital dental service, 1963, Volume: 21

    Topics: Acetaminophen; Amphetamine; Analgesics; Analgesics, Non-Narcotic; Anesthesia; Anesthesia, Dental; An

1963
COMPARATIVE EFFECTS OF D-, L AMPHETAMINE AND L-PHENYL-I-(PIPERIDYL-2'-)-I-ACETOXY-I-METHANE (R.P.-8228) IN ANTAGONIZING BARBITURATE HYPNOSIS.
    Archives internationales de pharmacodynamie et de therapie, 1963, Oct-01, Volume: 145

    Topics: Amphetamine; Amphetamines; Anesthesia; Anesthesia, Intravenous; Barbiturates; Cats; Hypnosis; Hypnot

1963
STRUCTURE-ACTIVITY RELATIONSHIP IN THE PHENYLISOPROPYLAMINE GROUP. V. THE ACTION OF DL-M AND P-DI-(2-AMINOPROPYL)-BENZENES ON THE CENTRAL NERVOUS SYSTEM.
    Archivum immunologiae et therapiae experimentalis, 1964, Volume: 12

    Topics: Amphetamine; Amphetamines; Anesthesia; Animals; Benzene; Central Nervous System; Chemistry, Pharmace

1964
INFLUENCE OF DOXAPRAM HYDROCHLORIDE ON RECOVERY FROM THIOPENTAL ANAESTHESIA.
    Canadian Anaesthetists' Society journal, 1965, Volume: 12

    Topics: Adolescent; Amphetamine; Amphetamines; Anesthesia; Anesthesia, Intravenous; Animals; Biomedical Rese

1965
EFFECT OF CATECHOLAMINE PRECURSORS AND PHENYLETHYLAMINES ON SPONTANEOUS ACTIVITY AND ON THE RESPONSE TO METHOHEXITAL ANAESTHESIA.
    Canadian Anaesthetists' Society journal, 1965, Volume: 12

    Topics: Amphetamine; Amphetamines; Anesthesia; Anesthetics; Animals; Arousal; Behavior, Animal; Catecholamin

1965
Correlation of the analgesic response to nitrous oxide and nitrous oxide-amphetamine with personality factors.
    The American journal of medicine, 1950, Volume: 8, Issue:4

    Topics: Amphetamine; Amphetamines; Analgesics; Anesthesia; Humans; Nitrous Oxide; Personality

1950
Analgesic effects of nitrous oxide and meperidine, alone and combined with amphetamine.
    The American journal of medicine, 1950, Volume: 8, Issue:4

    Topics: Amphetamine; Amphetamines; Analgesics; Anesthesia; Meperidine; Nitrous Oxide

1950
Pressor responses to ephedrine are mediated by a direct mechanism in the rat.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 316, Issue:1

    Topics: Amphetamine; Anesthesia; Animals; Blood Pressure; Catecholamines; Central Nervous System Stimulants;

2006
SPECT imaging of D2 dopamine receptors and endogenous dopamine release in mice.
    European journal of nuclear medicine and molecular imaging, 2008, Volume: 35, Issue:9

    Topics: Alcohols; Amphetamine; Anesthesia; Animals; Dopamine; Injections, Intraperitoneal; Injections, Intra

2008
Effect of reserpine on body temperature in the rat after pretreatment with amphetamine and monoamineoxidase inhibitors.
    Methods and findings in experimental and clinical pharmacology, 1982, Volume: 4, Issue:8

    Topics: Amphetamine; Anesthesia; Animals; Body Temperature; Female; Male; Monoamine Oxidase Inhibitors; Parg

1982
The release of endogenous GABA and glutamate from the cerebral cortex in the rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1981, Volume: 316, Issue:3

    Topics: Amino Acids; Amphetamine; Anesthesia; Animals; Cerebral Cortex; Electroencephalography; gamma-Aminob

1981
Effect of haloperidol and pimozide on acetylcholine output from the cerebral cortex in rats and guinea pigs.
    European journal of pharmacology, 1980, Jul-25, Volume: 65, Issue:2-3

    Topics: Acetylcholine; Acoustic Stimulation; Amphetamine; Anesthesia; Animals; Cerebral Cortex; Female; Guin

1980
Halothane anesthesia enhances the effect of dopamine uptake inhibition on interstitial levels of striatal dopamine.
    Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 350, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Anesthesia; Animals; Consciousness; Corpus Striatum; Do

1994
Antagonistic effects of stimulation of the paramedian reticular nucleus in the rat medulla oblongata and of amphetamine on locomotor activity and striatal release of dopamine-like material.
    Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 348, Issue:3

    Topics: Amphetamine; Anesthesia; Animals; Blood Pressure; Corpus Striatum; Depression, Chemical; Dopamine; E

1993
Amphetamine-induced activation of forebrain EEG is prevented by noradrenergic beta-receptor blockade in the halothane-anesthetized rat.
    Psychopharmacology, 2000, Volume: 148, Issue:3

    Topics: Amphetamine; Anesthesia; Animals; Electroencephalography; Halothane; Male; Norepinephrine; Prosencep

2000
Effect of modafinil on cerebral blood flow of anaesthetised rats. Comparison with amphetamine.
    Experimental brain research, 2000, Volume: 135, Issue:4

    Topics: Amphetamine; Anesthesia; Animals; Benzhydryl Compounds; Blood Pressure; Central Nervous System Stimu

2000
Analeptic and antianaleptic effects of naloxone and naltrexone in rabbits.
    Life sciences, 1978, Oct-23, Volume: 23, Issue:16

    Topics: Amphetamine; Anesthesia; Animals; Central Nervous System Stimulants; Male; Motor Activity; Naloxone;

1978
The pharmacology of a new potent, long acting neuroleptic, piflutixol.
    Acta pharmacologica et toxicologica, 1977, Volume: 41, Issue:4

    Topics: Adenylyl Cyclases; Amphetamine; Anesthesia; Animals; Apomorphine; Arousal; Barbiturates; Behavior, A

1977
D & L amphetamine stereoisomers: comparative potencies in affecting the firing of central dopaminergic and noradrenergic neurons.
    Psychopharmacology communications, 1975, Volume: 1, Issue:2

    Topics: Amphetamine; Anesthesia; Animals; Cerebral Ventricles; Dextroamphetamine; Dopamine; Neurons; Norepin

1975
[Influence of amphetamine and phenobarbital treatment on hexobarbital narcosis].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1967, Volume: 257, Issue:1

    Topics: Amphetamine; Anesthesia; Animals; Drug Synergism; Female; Hexobarbital; Phenobarbital; Rats

1967
[The effect of unithiol (2-mercapto-propane sulfonate sodium) on the motor activity stimulated by amphetamine, on evipan anesthesia and on the activity of dopamine-beta-hydroxylase].
    Eksperimentalna meditsina i morfologiia, 1974, Volume: 13, Issue:2

    Topics: Alkanesulfonates; Amphetamine; Anesthesia; Animals; Dopamine beta-Hydroxylase; Hexobarbital; Injecti

1974
Physiologic responses to equivalent doses of doxapram and various analeptic combinations in acute barbiturate narcosis in dogs.
    Toxicology and applied pharmacology, 1966, Volume: 8, Issue:3

    Topics: Amphetamine; Anesthesia; Animals; Barbiturates; Blood Pressure; Central Nervous System Stimulants; D

1966
Effects of monoamine oxidase inhibitors and amphetamine on hypothermia produced by halothane.
    British journal of pharmacology, 1970, Volume: 38, Issue:1

    Topics: Amphetamine; Anesthesia; Animals; Cats; Female; Halothane; Hydrazines; Hypothermia; Injections; Inje

1970
The lipolytic activity of amphetamine in the spinalised cat.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 9, Issue:1

    Topics: Amphetamine; Anesthesia; Animals; Cats; Chloralose; Cordotomy; Fatty Acids, Nonesterified; Female; H

1974
Experiments on antagonism of ketamine anesthesia in cats given adrenergic, serotonergic, and cholinergic stimulants alone and in combination.
    American journal of veterinary research, 1974, Volume: 35, Issue:1

    Topics: Amphetamine; Anesthesia; Animals; Cats; Female; Heart Rate; Injections, Intramuscular; Injections, I

1974
Age, ether narcosis and 'Weck'-amines.
    Experientia, 1974, Feb-15, Volume: 30, Issue:2

    Topics: Aging; Amphetamine; Anesthesia; Animals; Ethyl Ethers; Male; Rats; Time Factors

1974
Cardiovascular and gross behavioral effects of amphetamine, 2-amino-1-(2,5-dimethoxy-4-methylphenyl) propane (DOM) and 2-amino-1-(2,5-dimethoxy-4-methylphenyl) butane (BL-3912A) in the conscious dog.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 8, Issue:2

    Topics: Amphetamine; Anesthesia; Animals; Behavior, Animal; Blood Pressure; Butylamines; Dogs; DOM 2,5-Dimet

1974