amphetamine has been researched along with Amyotrophic Lateral Sclerosis in 2 studies
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Excerpt | Relevance | Reference |
|---|---|---|
| ""Amphetamine exposure" was defined as a prior use of amphetamine, methamphetamine or dextroamphetamine." | 1.33 | Amphetamine exposure is elevated in Parkinson's disease. ( Bekele, W; Christine, CW; Garwood, ER; McCulloch, CE, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, JK | 1 |
| Dedeoglu, A | 1 |
| Jenkins, BG | 1 |
| Garwood, ER | 1 |
| Bekele, W | 1 |
| McCulloch, CE | 1 |
| Christine, CW | 1 |
2 other studies available for amphetamine and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Longitudinal monitoring of motor neuron circuitry in FALS rats using in-vivo phMRI.
Topics: Amphetamine; Amyotrophic Lateral Sclerosis; Animals; Brain Mapping; Central Nervous System Stimulant | 2010 |
Amphetamine exposure is elevated in Parkinson's disease.
Topics: Adrenergic Agents; Aged; Amphetamine; Amphetamine-Related Disorders; Amyotrophic Lateral Sclerosis; | 2006 |