amphetamine has been researched along with Alloxan Diabetes in 13 studies
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These diabetic animals had a higher level of the spontaneous pain threshold, but displayed a reduced sensitivity of analgesic responses to morphine injection." | 3.67 | Alterations in physiologic functions and in brain monoamine content in streptozocin-diabetic rats. ( Chu, PC; Leu, SY; Lin, MT; Shian, LR, 1986) |
| "Amphetamine and cocaine increase extracellular levels of DA by acting on the DAT; thus, variations in DAT binding sites or activity might influence the action of some drugs of abuse." | 1.32 | Selective decreases in amphetamine self-administration and regulation of dopamine transporter function in diabetic rats. ( France, CP; Frazer, A; Galici, R; Galli, A; Gould, GG; Jones, DJ; Lin, RZ; Sanchez, TA; Saunders, C, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sevak, RJ | 5 |
| Koek, W | 4 |
| Owens, WA | 5 |
| Galli, A | 7 |
| Daws, LC | 5 |
| France, CP | 6 |
| Williams, JM | 1 |
| Saunders, C | 2 |
| Avison, MJ | 1 |
| Galici, R | 2 |
| Jones, DJ | 1 |
| Sanchez, TA | 1 |
| Frazer, A | 1 |
| Gould, GG | 1 |
| Lin, RZ | 1 |
| Chang, X | 1 |
| Javors, MA | 1 |
| Trulson, ME | 1 |
| MacKenzie, RG | 1 |
| Heaton, JP | 1 |
| Varrin, SJ | 1 |
| Murzi, E | 1 |
| Contreras, Q | 1 |
| Teneud, L | 1 |
| Valecillos, B | 1 |
| Parada, MA | 1 |
| De Parada, MP | 1 |
| Hernandez, L | 1 |
| Bellush, LL | 1 |
| Reid, SG | 1 |
| Medvedeva, NA | 1 |
| Kuznetsova, LV | 1 |
| Medvedev, OS | 1 |
| Chu, PC | 1 |
| Lin, MT | 1 |
| Shian, LR | 1 |
| Leu, SY | 1 |
13 other studies available for amphetamine and Alloxan Diabetes
| Article | Year |
|---|---|
Feeding conditions differentially affect the neurochemical and behavioral effects of dopaminergic drugs in male rats.
Topics: Amphetamine; Animals; Behavior, Animal; Blood Glucose; Body Weight; Brain Chemistry; Caloric Restric | 2008 |
Rescue of dopamine transporter function in hypoinsulinemic rats by a D2 receptor-ERK-dependent mechanism.
Topics: Amphetamine; Analysis of Variance; Animals; Blood Glucose; Body Weight; Brain; Brain Mapping; Corpus | 2012 |
Selective decreases in amphetamine self-administration and regulation of dopamine transporter function in diabetic rats.
Topics: Amphetamine; Animals; Blood Glucose; Cocaine; Diabetes Mellitus, Experimental; Dopamine; Dopamine Pl | 2003 |
Deficits in dopamine clearance and locomotion in hypoinsulinemic rats unmask novel modulation of dopamine transporters by amphetamine.
Topics: Amphetamine; Animals; Body Weight; Diabetes Mellitus, Experimental; Dopamine; Dopamine Agents; Dopam | 2005 |
Insulin replacement restores the behavioral effects of quinpirole and raclopride in streptozotocin-treated rats.
Topics: Amphetamine; Animals; Behavior, Animal; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; | 2007 |
Evidence for D2 receptor mediation of amphetamine-induced normalization of locomotion and dopamine transporter function in hypoinsulinemic rats.
Topics: Amphetamine; Animals; Blood Glucose; Brain; Brain Chemistry; Diabetes Mellitus, Experimental; Dopami | 2007 |
Behavioral effects of amphetamine in streptozotocin-treated rats.
Topics: Amphetamine; Animals; Behavior, Animal; Blood Glucose; Body Weight; Conditioning, Psychological; Dia | 2008 |
Subsensitivity to 5-hydroxytryptamine agonists occurs in streptozocin-diabetic rats with no change in [3H]-5-HT receptor binding.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Behavior, Animal; Brain Chemistry; Diabetes Mellitus, Exp | 1981 |
Effects of streptozotocin-induced diabetes on dopaminergic functioning in the rat: analysis of yawning behavior.
Topics: Amphetamine; Animals; Apomorphine; Brain Chemistry; Diabetes Mellitus, Experimental; Dopamine; Male; | 1993 |
Diabetes decreases limbic extracellular dopamine in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Chromatography, High Pressure Liquid; Diabetes | 1996 |
Altered behavior and neurochemistry during short-term insulin withdrawal in streptozocin-induced diabetic rats.
Topics: Amphetamine; Animals; Diabetes Mellitus, Experimental; Dopamine; Hyperglycemia; Hypothalamo-Hypophys | 1991 |
[Disordered sympathetic regulation of the functions of the cardiovascular system in rats with streptozotocin diabetes].
Topics: Amphetamine; Animals; Cardiovascular System; Diabetes Mellitus, Experimental; Hemodynamics; Male; No | 1991 |
Alterations in physiologic functions and in brain monoamine content in streptozocin-diabetic rats.
Topics: Amphetamine; Animals; Body Temperature Regulation; Brain; Brain Chemistry; Brain Stem; Corpus Striat | 1986 |