Page last updated: 2024-10-25

amphetamine and Agitation, Psychomotor

amphetamine has been researched along with Agitation, Psychomotor in 13 studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Research Excerpts

ExcerptRelevanceReference
" Mice treated with PGW5 (25 and 50mg/kg/d) for 28 days did not show toxic effects in terms of weight gain and blood-chemistry analysis."5.40A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia. ( Bidder, M; Gil-Ad, I; Kramer, M; Portnoy, M; Taler, M; Tarasenko, I; Weizman, A, 2014)
" In the context of bipolar disorder, amphetamine-induced hyperactivity (AIH) is a frequently used screening model for antimanic effects."3.91Questioning the predictive validity of the amphetamine-induced hyperactivity model for screening mood stabilizing drugs. ( Einat, H; Lan, A, 2019)
" Mice treated with PGW5 (25 and 50mg/kg/d) for 28 days did not show toxic effects in terms of weight gain and blood-chemistry analysis."1.40A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia. ( Bidder, M; Gil-Ad, I; Kramer, M; Portnoy, M; Taler, M; Tarasenko, I; Weizman, A, 2014)
"In case 3, the patient exhibited restlessness on the first day and one of the removed packets had ruptured."1.39Methamphetamine and amphetamine concentrations in survivors of body-packer syndrome in Japan. ( Hara, K; Hayashida, M; Mashiko, K; Ohno, Y; Saito, N; Uekusa, K; Waters, B, 2013)
"Amphetamine has been used in Attention Deficit Hyperactivity Disorder (ADHD), narcolepsy, and as an appetite suppressant either as the racemate or in different proportions of its enantiomers."1.33Quantitation of R-(-)- and S-(+)-amphetamine in hair and blood by gas chromatography-mass spectrometry: an application to compliance monitoring in adult-attention deficit hyperactivity disorder treatment. ( Ahlner, J; Kronstrand, R; Nyström, I; Trygg, T; Woxler, P, 2005)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19903 (23.08)18.7374
1990's0 (0.00)18.2507
2000's5 (38.46)29.6817
2010's5 (38.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lan, A1
Einat, H1
Gil-Ad, I1
Portnoy, M1
Tarasenko, I1
Bidder, M1
Kramer, M1
Taler, M1
Weizman, A1
FROMMEL, E1
FLEURY, C1
BEGUIN, M1
Pase, CS1
Roversi, K2
Trevizol, F1
Kuhn, FT1
Dias, VT1
Vey, LT1
Antoniazzi, CT1
Barcelos, RC1
Bürger, ME1
Vadnie, CA1
Ayers-Ringler, J1
Oliveros, A1
Abulseoud, OA1
Choi, S1
Hitschfeld, MJ1
Choi, DS1
Uekusa, K1
Hayashida, M1
Saito, N1
Mashiko, K1
Hara, K1
Waters, B1
Ohno, Y1
DELPHAUT, J1
LANZA, M1
Nyström, I1
Trygg, T1
Woxler, P1
Ahlner, J1
Kronstrand, R1
Brann, MR1
Hacker, M1
Finnerty, M1
Ellis, J1
Lenox, RH1
Ehrlich, YH1
Vanderschuren, LJ1
Schoffelmeer, AN1
Wardeh, G1
De Vries, TJ1
Balla, A1
Koneru, R1
Smiley, J1
Sershen, H1
Javitt, DC1
Lipska, BK1
Halim, ND1
Segal, PN1
Weinberger, DR1
Pinna, GA1
Pirisi, MA1
Chelucci, G1
Mussinu, JM1
Murineddu, G1
Loriga, G1
D'Aquila, PS1
Serra, G1

Other Studies

13 other studies available for amphetamine and Agitation, Psychomotor

ArticleYear
Questioning the predictive validity of the amphetamine-induced hyperactivity model for screening mood stabilizing drugs.
    Behavioural brain research, 2019, 04-19, Volume: 362

    Topics: Amphetamine; Animals; Anticonvulsants; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Central

2019
A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:3

    Topics: Alanine; Amphetamine; Animals; Antipsychotic Agents; Anxiety; Benzodiazepines; Brain; Central Nervou

2014
[On the pharmacodynamics of a new neuroleptic: the alpha-isomer of 2-chloro-9-(3-dimethylaminopropylidene)-thiaxanthene HC1 or tractan. Action on the sleep centers, on motor excitation caused by nikethamide, on pentylenetetrazole, electroshock and psychom
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1960, Volume: 154

    Topics: Amphetamine; Amphetamines; Antipsychotic Agents; Central Nervous System; Electroshock; Humans; Niket

1960
Chronic consumption of trans fat can facilitate the development of hyperactive behavior in rats.
    Physiology & behavior, 2015, Volume: 139

    Topics: Adaptation, Psychological; Akathisia, Drug-Induced; Amphetamine; Animals; Central Nervous System Sti

2015
Antipsychotic-like effects of a neurotensin receptor type 1 agonist.
    Behavioural brain research, 2016, May-15, Volume: 305

    Topics: Amphetamine; Analysis of Variance; Animals; Antipsychotic Agents; Brain; Central Nervous System Stim

2016
Methamphetamine and amphetamine concentrations in survivors of body-packer syndrome in Japan.
    Forensic science international, 2013, Apr-10, Volume: 227, Issue:1-3

    Topics: Adult; Amphetamine; Central Nervous System Stimulants; Crime; Foreign Bodies; Forensic Toxicology; G

2013
[Effect of certain ataraxic drugs on agitations induced with amphetamine and cocaine in white mice].
    Journal de physiologie, 1958, Volume: 50, Issue:2

    Topics: Amphetamine; Amphetamines; Animals; Cocaine; Mice; Psychomotor Agitation; Seizures; Tranquilizing Ag

1958
Quantitation of R-(-)- and S-(+)-amphetamine in hair and blood by gas chromatography-mass spectrometry: an application to compliance monitoring in adult-attention deficit hyperactivity disorder treatment.
    Journal of analytical toxicology, 2005, Volume: 29, Issue:7

    Topics: Adult; Amphetamine; Central Nervous System Stimulants; Drug Monitoring; Female; Gas Chromatography-M

2005
Automated analysis of stereotypic behavior induced by psychomotor stimulants.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:1

    Topics: Amphetamine; Animals; Apomorphine; Autoanalysis; Drug Interactions; Haloperidol; Humans; Male; Metho

1983
Dissociable effects of the kappa-opioid receptor agonists bremazocine, U69593, and U50488H on locomotor activity and long-term behavioral sensitization induced by amphetamine and cocaine.
    Psychopharmacology, 2000, Volume: 150, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amphetamin

2000
Continuous phencyclidine treatment induces schizophrenia-like hyperreactivity of striatal dopamine release.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 25, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Central Nervous System Stimulants; Corpus Stri

2001
Effects of reversible inactivation of the neonatal ventral hippocampus on behavior in the adult rat.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Apr-01, Volume: 22, Issue:7

    Topics: Age Factors; Aging; Amphetamine; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal;

2002
Synthesis and D(2)-like binding affinity of new derivatives of N-(1-ethyl-2-pyrrolidinylmethyl)-4,5-dihydro-1H-benzo[g]indole-3-carboxamide and related 4H-[1]benzothiopyrano[4,3-b]pyrrole and 5,6-dihydro-4H-benzo[6,7]cyclohepta[b]pyrrole-3-carboxamide ana
    Bioorganic & medicinal chemistry, 2002, Volume: 10, Issue:8

    Topics: Amides; Amphetamine; Animals; Antipsychotic Agents; Indoles; Protein Binding; Psychomotor Agitation;

2002