amphetamine has been researched along with Adverse Drug Event in 23 studies
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this pharmacokinetic (PK) study in healthy adults, we sought to: (1) compare the PK properties of a novel amphetamine extended-release orally disintegrating tablet formulation (Adzenys XR-ODT™ [AMP XR-ODT]) to a reference extended-release mixed amphetamine salts (MAS ER) formulation and (2) assess the effect of food on AMP XR-ODT." | 2.82 | A randomized crossover study to assess the pharmacokinetics of a novel amphetamine extended-release orally disintegrating tablet in healthy adults. ( Engelking, D; McMahen, R; Sikes, C; Stark, JG, 2016) |
| " Administration of low doses of SCs can cause euphoria and increased alertness, and administration of high doses or chronic use of cathinones can cause serious adverse effects such as hallucinations, delirium, hyperthermia and tachycardia." | 1.72 | Toxicological Analysis of Intoxications with Synthetic Cathinones. ( Czekaj, P; Pieprzyca, E; Skowronek, R, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (65.22) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 4 (17.39) | 24.3611 |
| 2020's | 2 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| Pieprzyca, E | 1 |
| Skowronek, R | 1 |
| Czekaj, P | 1 |
| Elliott, J | 1 |
| Johnston, A | 1 |
| Husereau, D | 1 |
| Kelly, SE | 1 |
| Eagles, C | 1 |
| Charach, A | 1 |
| Hsieh, SC | 1 |
| Bai, Z | 1 |
| Hossain, A | 1 |
| Skidmore, B | 1 |
| Tsakonas, E | 1 |
| Chojecki, D | 1 |
| Mamdani, M | 1 |
| Wells, GA | 1 |
| Winkelman, TNA | 1 |
| Admon, LK | 1 |
| Jennings, L | 1 |
| Shippee, ND | 1 |
| Richardson, CR | 1 |
| Bart, G | 1 |
| Stark, JG | 1 |
| Engelking, D | 1 |
| McMahen, R | 1 |
| Sikes, C | 1 |
| Thompson, BL | 1 |
| Levitt, P | 1 |
| Stanwood, GD | 1 |
| Rasmussen, N | 1 |
| BECKER, WF | 1 |
| KEITER, WE | 1 |
| ARNOLD, JH | 1 |
| Hansen, T | 1 |
| Walker, KA | 1 |
| Bourgeois, P | 1 |
| Aeschlimann, A | 1 |
| Evans, HL | 1 |
| Bushnell, PJ | 1 |
| Taylor, JD | 1 |
| Monico, A | 1 |
| Teal, JJ | 1 |
| Pontecorvo, MJ | 1 |
| Schwartz, JF | 1 |
| Dille, JR | 1 |
| Mohler, SR | 1 |
| Messini, M | 1 |
| Willetts, GS | 1 |
| Hopkins, DJ | 1 |
| Aschenbrenner, R | 1 |
| Reynolds, HH | 1 |
| Mitchell, DF | 1 |
| Silverman, A | 1 |
| Scher, J | 1 |
7 reviews available for amphetamine and Adverse Drug Event
| Article | Year |
|---|---|
Pharmacologic treatment of attention deficit hyperactivity disorder in adults: A systematic review and network meta-analysis.
Topics: Adult; Amphetamine; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Bayes | 2020 |
Prenatal exposure to drugs: effects on brain development and implications for policy and education.
Topics: Alcohols; Amphetamine; Antidepressive Agents; Brain; Child; Crack Cocaine; Drug-Related Side Effects | 2009 |
Drug-induced scleroderma.
Topics: Amphetamine; Bleomycin; Cocaine; Diethylpropion; Drug-Related Side Effects and Adverse Reactions; Hu | 1991 |
Drug-induced neurologic disorders in childhood.
Topics: Adolescent; Adult; Age Factors; Aged; Amphetamine; Anesthesia, Inhalation; Anesthesia, Local; Animal | 1971 |
[On the harmful effects of drugs. II].
Topics: Adrenergic beta-Antagonists; Allopurinol; Amphetamine; Animals; Anti-Bacterial Agents; Contraceptive | 1970 |
Systemic therapeutic agents and glaucoma.
Topics: Alkaloids; Amphetamine; Anterior Chamber; Anthropometry; Antiparkinson Agents; Atropa belladonna; Dr | 1972 |
Nonhuman primates in the study of toxicological effects on the central nervous system: a review.
Topics: Amphetamine; Animals; Central Nervous System; Chlordiazepoxide; Chlorpromazine; Drug-Related Side Ef | 1969 |
1 trial available for amphetamine and Adverse Drug Event
| Article | Year |
|---|---|
A randomized crossover study to assess the pharmacokinetics of a novel amphetamine extended-release orally disintegrating tablet in healthy adults.
Topics: Administration, Oral; Adult; Amphetamine; Area Under Curve; Attention Deficit Disorder with Hyperact | 2016 |
15 other studies available for amphetamine and Adverse Drug Event
| Article | Year |
|---|---|
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Toxicological Analysis of Intoxications with Synthetic Cathinones.
Topics: Alkaloids; Amphetamine; Chromatography, Liquid; Drug-Related Side Effects and Adverse Reactions; Eth | 2022 |
Evaluation of Amphetamine-Related Hospitalizations and Associated Clinical Outcomes and Costs in the United States.
Topics: Adolescent; Adult; Aged; Amphetamine; Amphetamine-Related Disorders; Cross-Sectional Studies; Drug-R | 2018 |
Medical science and the military: the Allies' use of amphetamine during World War II.
Topics: Amphetamine; Drug-Related Side Effects and Adverse Reactions; History, 20th Century; Military Medici | 2011 |
[Therapy and clinical aspects of acute barbituric acid intoxications].
Topics: Amphetamine; Amphetamines; Barbiturates; Drug-Related Side Effects and Adverse Reactions; Humans; Po | 1954 |
Acute dexedrine intoxication in children.
Topics: Amphetamine; Central Nervous System Agents; Child; Dextroamphetamine; Drug-Related Side Effects and | 1955 |
[Studies on the biotransformation of drugs and its significance in pharmaceutical industry].
Topics: Amphetamine; Animals; Drug Industry; Drug-Related Side Effects and Adverse Reactions; Humans; Pharma | 1967 |
Motor-racing.
Topics: Airway Obstruction; Alcohol Drinking; Amphetamine; Athletic Injuries; Automobile Driver Examination; | 1975 |
A system for assessing toxicity of chemicals by continuous monitoring of homecage behaviors.
Topics: Amphetamine; Animals; Behavior, Animal; Circadian Rhythm; Drug Evaluation, Preclinical; Drug-Related | 1986 |
Drug and toxic hazrds in general aviation. AM-68-16.
Topics: Accidents, Aviation; Adult; Alcoholic Intoxication; Amphetamine; Analgesics; Carbon Monoxide Poisoni | 1968 |
Drugs that cause depression.
Topics: Amphetamine; Antipsychotic Agents; Brain; Contraceptives, Oral; Depression; Drug-Related Side Effect | 1972 |
[The doctor's responsibility and risk in the prescribing of drugs].
Topics: Adult; Amphetamine; Appetite Depressants; Drug and Narcotic Control; Drug Industry; Drug Packaging; | 1973 |
Undesirable side reactions to drugs.
Topics: Amphetamine; Diuretics; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Huma | 1968 |
What are our dangerous drugs? 2.
Topics: Amphetamine; Caffeine; Cocaine; Dentistry; Drug-Related Side Effects and Adverse Reactions; Humans | 1971 |
Patterns and profiles of addiction and drug abuse.
Topics: Amphetamine; Drug-Related Side Effects and Adverse Reactions; Ethnology; Hallucinogens; Humans; Juri | 1966 |