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amphetamine and Acute Liver Injury, Drug-Induced

amphetamine has been researched along with Acute Liver Injury, Drug-Induced in 13 studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Research Excerpts

ExcerptRelevanceReference
"Amphetamine treatment caused an acute rise in core body temperature to 40 degrees C for at least 1 hr and increased hsp25 and hsp70i levels, as measured by Western blotting, at 6, 24, 48, and 72 hr with no apparent induction of other hsps (hsp60, hsc70, or hsp90)."1.30Protection against hepatotoxicity by a single dose of amphetamine: the potential role of heat shock protein induction. ( Roberts, SM; Salminen, WF; Voellmy, R, 1997)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's3 (23.08)18.2507
2000's0 (0.00)29.6817
2010's4 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fourches, D1
Barnes, JC1
Day, NC1
Bradley, P1
Reed, JZ1
Tropsha, A1
Liu, Z1
Shi, Q1
Ding, D1
Kelly, R1
Fang, H1
Tong, W2
Chen, M1
Suzuki, A1
Thakkar, S1
Yu, K1
Hu, C1
Carvalho, M1
Carmo, H1
Costa, VM1
Capela, JP1
Pontes, H1
Remião, F1
Carvalho, F1
Bastos, Mde L1
GOLDBERG, LI1
Salminen, WF1
Voellmy, R1
Roberts, SM1
Lin, X1
Levitsky, DA1
King, JM1
Campbell, TC1
Bakheit, AM1
Min, KW1
Gyorkey, F1
Cain, GD1
Gastpar, M1
Ladewig, D1
Richter, R1
Weidmann, M1
Lagacé, R1
Vtiurin, BV1
Kalashnikova, MM1
Weizel, A1
Linhart, P1
Heilmann, K1

Reviews

3 reviews available for amphetamine and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr

2016
Toxicity of amphetamines: an update.
    Archives of toxicology, 2012, Volume: 86, Issue:8

    Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Chemical and

2012
MONOAMINE OXIDASE INHIBITORS. ADVERSE REACTIONS AND POSSIBLE MECHANISMS.
    JAMA, 1964, Nov-02, Volume: 190

    Topics: Amphetamine; Amphetamines; Chemical and Drug Induced Liver Injury; Headache; Hematologic Diseases; H

1964

Other Studies

10 other studies available for amphetamine and Acute Liver Injury, Drug-Induced

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI

2010
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Protection against hepatotoxicity by a single dose of amphetamine: the potential role of heat shock protein induction.
    Toxicology and applied pharmacology, 1997, Volume: 147, Issue:2

    Topics: Acetaminophen; Amphetamine; Animals; Bromobenzenes; Carbon Tetrachloride; Chemical and Drug Induced

1997
The promotion effect of anorectic drugs on aflatoxin B(1)-induced hepatic preneoplastic foci.
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: Adipose Tissue, Brown; Aflatoxin B1; Amphetamine; Animals; Appetite Depressants; Biomarkers; Body Te

1999
Intracerebral haemorrhage in previously healthy young adults.
    Postgraduate medical journal, 1999, Volume: 75, Issue:886

    Topics: Adult; Amphetamine; Central Nervous System Stimulants; Cerebral Hemorrhage; Chemical and Drug Induce

1999
Talc granulomata in liver disease in narcotic addicts.
    Archives of pathology, 1974, Volume: 98, Issue:5

    Topics: Adult; Amphetamine; Barbiturates; Biopsy; Cannabis; Chemical and Drug Induced Liver Injury; Granulom

1974
[Intravenous drug administration and hepatitis among young people in Basel].
    Schweizerische medizinische Wochenschrift, 1974, Aug-24, Volume: 104, Issue:34

    Topics: Adolescent; Adult; Age Factors; Amphetamine; Analgesics; Animals; Antitussive Agents; Cannabis; Chem

1974
[Special aspect of hepatitis in people abusing drugs].
    La Vie medicale au Canada francais, 1972, Volume: 1, Issue:6

    Topics: Amphetamine; Chemical and Drug Induced Liver Injury; Humans; Substance-Related Disorders

1972
[Functional morphology of the nuclear membrane and its pores].
    Arkhiv patologii, 1972, Volume: 34, Issue:7

    Topics: Amphetamine; Animals; Burns; Carbon Tetrachloride Poisoning; Cell Nucleus; Cerebral Cortex; Chemical

1972
[Hepatitides following narcotics and hallucinogens].
    Deutsche medizinische Wochenschrift (1946), 1971, Mar-12, Volume: 96, Issue:11

    Topics: Adult; Amphetamine; Cannabis; Chemical and Drug Induced Liver Injury; Female; Hepatitis B Antigens;

1971