amoxicillin-potassium-clavulanate-combination and Pilonidal-Sinus

amoxicillin-potassium-clavulanate-combination has been researched along with Pilonidal-Sinus* in 3 studies

Trials

1 trial(s) available for amoxicillin-potassium-clavulanate-combination and Pilonidal-Sinus

ArticleYear
Single-dose metronidazole versus 5-day multi-drug antibiotic regimen in excision of pilonidal sinuses with primary closure: a prospective randomised controlled double-blinded study.
    International journal of colorectal disease, 2002, Volume: 17, Issue:5

    This pilot study examines whether single-dose intravenous metronidazole preoperatively is at least as effective as a broad-spectrum multi-drug regimen in preventing infection-related wound complications following excision of pilonidal sinuses with primary closure.. A double-blinded study with 50 patients randomised to receiving either a single drug (intravenous metronidazole 500 mg) prophylaxis preoperatively or multi-drug cover (intravenous cefuroxime 1.5 g and metronidazole 0.5 g preoperatively, and oral co-amoxiclav 375 mg 8-hourly postoperatively). They will be reviewed 1, 2 and 4 weeks postoperatively. The wound will be graded as: I, healthy; II, redness and swelling of edges; III, abscess related to a suture; IV, spreading wound infection; V, wound breakdown. Other factors considered are the distance from the lowest wound margin to the anal verge, and previous pilonidal sinus surgery.. Results awaited.. Single-dose metronidazole seems an appropriate and low-cost antibiotic to consider for prophylaxis in pilonidal sinus surgery. This study will form the base for a trial to be conducted in larger numbers as a randomised controlled trial in order to have statistical power.

    Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; Cefuroxime; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Elective Surgical Procedures; Female; Humans; Male; Metronidazole; Pilonidal Sinus; Pilot Projects; Prospective Studies; Recurrence; Surgical Wound Infection; Treatment Outcome; United Kingdom

2002

Other Studies

2 other study(ies) available for amoxicillin-potassium-clavulanate-combination and Pilonidal-Sinus

ArticleYear
Excision and primary closure using the Karydakis flap for the treatment of pilonidal disease: outcomes from a single institution.
    World journal of surgery, 2011, Volume: 35, Issue:8

    Chronic pilonidal disease is a debilitating condition that typically affects young adults. There is a wide variety of available therapeutic strategies reflecting the inconsistent outcomes attributed to the various operative approaches. The majority involve excision of the sinus tract followed by either primary closure or healing by secondary intention. A variety of closure approaches exist. There remains uncertainty as to which is more effective. The aim of the current study was to determine subjective and objective outcomes following excision and Karydakis flap closure in a unit where this technique is the standard of care in the management of chronic pilonidal disease.. This study involving consecutive patients with chronic pilonidal disease was conducted over a 4-year period. A tailored patient satisfaction questionnaire was given to each patient. Postoperative primary and secondary outcomes were evaluated. The mean follow-up time was 30 months.. One hundred six consecutive patients (33 female, 73 male) underwent excision and primary closure using the Karydakis flap. Ninety-two completed questionnaires were returned (87% response rate). Patients consulted their general practitioner 2.8 times (mean) and 46% received empirical oral antimicrobial therapy prior to referral for a surgical opinion. The mean time lost to work/school following the Karydakis flap repair was 13 days (range 3-33). Successful treatment was achieved in 96.3% of cases and 92% of patients were satisfied with their operative result.. Excision and primary closure with Karydakis flap is an effective treatment for chronic pilonidal disease. It is associated with low morbidity, early return to premorbid functioning, and a high degree of patient satisfaction (92%).

    Topics: Abscess; Adolescent; Adult; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Antibiotic Prophylaxis; Female; Germany; Humans; Male; Middle Aged; Pain, Postoperative; Patient Satisfaction; Pilonidal Sinus; Postoperative Complications; Surgical Flaps; Surveys and Questionnaires; Suture Techniques; Young Adult

2011
Case records of the Massachusetts General Hospital. Case 14-2005. A 38-year-old man with fever and blurred vision.
    The New England journal of medicine, 2005, May-12, Volume: 352, Issue:19

    Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Biopsy; Colitis, Ulcerative; Colon; Diagnosis, Differential; Fever; Humans; Male; Pilonidal Sinus; Postoperative Complications; Purpura; Retinal Vasculitis; Skin; Thrombophlebitis; Vasculitis; Vision Disorders

2005