amoxicillin-potassium-clavulanate-combination and Paranasal-Sinus-Neoplasms

Maxillofacial district osteomas are benign lesions with very slow growth. The most frequent localization is the frontal sinus, about 57% of all paranasal cavity osteomas; less frequently, they can be located in the ethmoidal sinus or sphenoidal and maxillary. Etiology has not completely clarified yet; nevertheless, there are 3 main pathogenetic theories: osteogenic, traumatic, and infective. Open procedures represent the gold standard, but there is still an unsolved debate for the best treatment option. Endoscopic techniques offer an alternative approach, enabling closer and more direct visualization of the anatomy as well as avoiding damage to surrounding structures. In our study, we analyzed all patients treated with endoscopic approach for paranasal sinus osteomas in the ENT unit of the University of Varese and compared them with patients treated for the same pathology with open surgery in the Maxillo-facial Department of the University of Rome "La Sapienza." The purpose of the work was to compare the advantages and disadvantages of the 2 procedures. In conclusion, this study underlines the importance of flexibility in surgical approach decision, which must fit the different issues of the pathology and of the patient.

Topics: Adolescent; Adult; Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Contraindications; Endoscopes; Endoscopy; Ethmoid Sinus; Female; Follow-Up Studies; Frontal Sinus; Humans; Length of Stay; Male; Maxillary Sinus Neoplasms; Middle Aged; Nasal Cavity; Nasal Septum; Osteoma; Osteotomy; Paranasal Sinus Neoplasms; Periosteum; Sphenoid Sinus; Surgical Flaps; Tomography, X-Ray Computed; Young Adult

Sudden onset of bilateral blindness is rare; hysteria, cortical infarction or bilateral central retinal arterial occlusion can cause this.. The authors describe a single case of sudden onset bilateral blindness in a patient with nasopharyngeal carcinoma, which is unusual. Biopsy revealed a high-grade lymphoma. After treatment the patient made a complete visual recovery, with no evidence of visual sequelae and no clear reasons for this complete recovery.. CT and MR imaging did not demonstrate any lesions invading any part of the visual pathway or even indeed the occipital cortex. High dose steroids may have reduced the mass effect of the tumour or the blindness may have been hysterical but is unlikely.

Topics: Amoxicillin-Potassium Clavulanate Combination; Blindness; Dexamethasone; Drug Therapy, Combination; Female; Humans; Lymphoma, Non-Hodgkin; Magnetic Resonance Imaging; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Paranasal Sinus Neoplasms; Tomography, X-Ray Computed