amoxicillin-potassium-clavulanate-combination and Hemolytic-Uremic-Syndrome

We report Hemolytic Uremic Syndrome (HUS) induced by Streptococcus pneumoniae in a 20 month-old girl. She responded well to hemodialysis.

Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Female; Hemolytic-Uremic Syndrome; Humans; Infant; Pneumococcal Infections; Risk Factors; Streptococcus pneumoniae

A 43-year-old female with Staphyloccocus-induced perianal abscess, was admitted to hospital because of a clinical picture of acute renal failure and thrombotic microangiopathy. Schistocytes, thrombopenia, a negative Coombs test and no detectable plasma haptoglobin were diagnostic for thrombotic microangiopathy. Antibiotics, surgical drainage, plasmapheresis and fresh frozen plasma were given with a favourable evolution. We review the prognostic factors determining recovery of renal function and hematological abnormalities.

Topics: Abscess; Acute Kidney Injury; Adult; Amoxicillin-Potassium Clavulanate Combination; Anal Canal; Debridement; Drug Therapy, Combination; Female; Hemolytic-Uremic Syndrome; Humans; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Plasma; Plasmapheresis; Staphylococcal Infections; Thrombocytopenia

Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ceftriaxone; Child, Preschool; Combined Modality Therapy; Drug Therapy, Combination; Erythrocyte Transfusion; Hemolytic-Uremic Syndrome; Humans; Incidence; Male; Pneumococcal Infections; Prognosis; Risk Factors; Severity of Illness Index; Treatment Outcome