amoxicillin-potassium-clavulanate-combination and Blindness

A 4-year-old castrated male Chihuahua was evaluated because of unilateral vision loss following extraoral administration of a caudal maxillary nerve block during a dental procedure.. The menace response was absent in the left eye, but the pupillary light reflex was intact. Vitreal hemorrhages and opacities were present on ophthalmic examination of the left eye. Ultrasonographic findings were supportive of the clinical findings. The posterior lens capsule and retina appeared to be undisturbed.. Treatment consisted of administration of carprofen and prophylactic administration of amoxicillin-clavulanate. Vision was clinically normal with an intact menace response 1 week later.. Findings indicated that intravitreal injection of the local anesthetic agent should be considered as a potential complication when performing nerve blocks prior to dental procedures in dogs.

Topics: Amoxicillin-Potassium Clavulanate Combination; Anesthetics, Local; Animals; Blindness; Bupivacaine; Carbazoles; Dog Diseases; Dogs; Intravitreal Injections; Male; Medical Errors

Sudden onset of bilateral blindness is rare; hysteria, cortical infarction or bilateral central retinal arterial occlusion can cause this.. The authors describe a single case of sudden onset bilateral blindness in a patient with nasopharyngeal carcinoma, which is unusual. Biopsy revealed a high-grade lymphoma. After treatment the patient made a complete visual recovery, with no evidence of visual sequelae and no clear reasons for this complete recovery.. CT and MR imaging did not demonstrate any lesions invading any part of the visual pathway or even indeed the occipital cortex. High dose steroids may have reduced the mass effect of the tumour or the blindness may have been hysterical but is unlikely.

Topics: Amoxicillin-Potassium Clavulanate Combination; Blindness; Dexamethasone; Drug Therapy, Combination; Female; Humans; Lymphoma, Non-Hodgkin; Magnetic Resonance Imaging; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Paranasal Sinus Neoplasms; Tomography, X-Ray Computed