amoxicillin-potassium-clavulanate-combination and Blepharitis

Anthrax is an infectious disease that is not well known by ophthalmologists. In its cutaneous form, it may produce lesions of the eyelids. We report eight cases of palpebral anthrax. All patients presented with a black necrotic eschar and a tegumentary edema, with a history of contact with sick animals. The curative treatment was based on intravenous penicillin G in four cases and amoxicillin-clavulanic acid in the four other cases. The palpebral lesions resolved, leaving no clinical evidence of eyelid abnormalities in six patients. Only two patients developed a cicatricial ectropion and a palpebral symphysis. Although palpebral anthrax is a rare disease in humans, ophthalmologists should be aware of its symptoms and management.

Topics: Adolescent; Adult; Aged; Amoxicillin-Potassium Clavulanate Combination; Anthrax; Blepharitis; Child; Conjunctivitis, Bacterial; Ectropion; Female; Humans; Male; Middle Aged; Penicillin G

We report here a rare case of simultaneous onset of preseptal cellulitis in twins. The absence of any infection in three other siblings during this period would suggest that the twins may not have developed simultaneous lid infection by sheer coincidence. The authors discuss the possible mechanism and emphasize the need for close surveillance of the twin of an index case with ocular infection.

Topics: Amoxicillin-Potassium Clavulanate Combination; Blepharitis; Cefotaxime; Cellulitis; Diseases in Twins; Drug Therapy, Combination; Follow-Up Studies; Humans; Infant; Infusions, Intravenous; Male; Risk Assessment; Severity of Illness Index; Treatment Outcome; Twins, Monozygotic