amoxicillin-potassium-clavulanate-combination and Arthritis

This case series considers the incidence of patients taking bisphosphonate medication that suffer with bisphosphonate-related osteonecrosis of the jaw (BRONJ) following an exodontia procedure. Forty five such patients who attended the Wigan Royal Albert Edward Infirmary (RAEI) Oral and Maxillofacial Surgery (OMFS) department for an exodontia procedure were examined. A patient's age, gender, exodontia technique, bisphosphonate route (Oral/IV), smoking status and reason for taking the bisphosphonates, eg osteoporosis/cancer/ arthritis was considered. All of the patients that experienced BRONJ were smokers.. Bisphosphonates are now widely accepted for the management of medical conditions, including arthritis, osteoporosis and various forms of cancer. Such patients are regularly referred to OMFS departments for dental extractions.

Topics: Administration, Intravenous; Administration, Oral; Aged; Amoxicillin-Potassium Clavulanate Combination; Antibiotic Prophylaxis; Arthritis; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Female; Humans; Male; Middle Aged; Neoplasms; Osteoporosis; Pamphlets; Patient Education as Topic; Retrospective Studies; Risk Factors; Smoking; Tooth Extraction

Topics: Amoxicillin-Potassium Clavulanate Combination; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Arthritis; Clarithromycin; Drug Therapy, Combination; Humans; Hydrocortisone; Lung Diseases, Interstitial; Male; Middle Aged; Prednisolone; Rituximab; Treatment Outcome