amoxapine and Plague
amoxapine has been researched along with Plague in 1 studies
Amoxapine: The N-demethylated derivative of the antipsychotic agent LOXAPINE that works by blocking the reuptake of norepinephrine, serotonin, or both; it also blocks dopamine receptors. Amoxapine is used for the treatment of depression.
amoxapine : A dibenzooxazepine compound having a chloro substituent at the 2-position and a piperazin-1-yl group at the 11-position.
Plague: An acute infectious disease caused by YERSINIA PESTIS that affects humans, wild rodents, and their ectoparasites. This condition persists due to its firm entrenchment in sylvatic rodent-flea ecosystems throughout the world. Bubonic plague is the most common form.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " A total of 17 prioritized drugs, based on efficacy in in vitro screens, were chosen for further evaluation in a murine model of pneumonic plague to delineate if in vitro efficacy could be translated in vivo Three drugs, doxapram (DXP), amoxapine (AXPN), and trifluoperazine (TFP), increased animal survivability despite not exhibiting any direct bacteriostatic or bactericidal effect on Y." | 3.83 | New Role for FDA-Approved Drugs in Combating Antibiotic-Resistant Bacteria. ( Andersson, JA; Chauhan, S; Chopra, AK; Dann, SM; Fitts, EC; Kirtley, ML; Motin, VL; Peniche, AG; Ponnusamy, D; Rosenzweig, JA; Sha, J, 2016) |
Research
Studies (1)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Andersson, JA | 1 |
| Fitts, EC | 1 |
| Kirtley, ML | 1 |
| Ponnusamy, D | 1 |
| Peniche, AG | 1 |
| Dann, SM | 1 |
| Motin, VL | 1 |
| Chauhan, S | 1 |
| Rosenzweig, JA | 1 |
| Sha, J | 1 |
| Chopra, AK | 1 |
Other Studies
1 other study available for amoxapine and Plague
| Article | Year |
|---|---|
New Role for FDA-Approved Drugs in Combating Antibiotic-Resistant Bacteria.
Topics: Amoxapine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Clostridioides difficile | 2016 |