amoxapine has been researched along with Disease Models, Animal in 5 studies
Amoxapine: The N-demethylated derivative of the antipsychotic agent LOXAPINE that works by blocking the reuptake of norepinephrine, serotonin, or both; it also blocks dopamine receptors. Amoxapine is used for the treatment of depression.
amoxapine : A dibenzooxazepine compound having a chloro substituent at the 2-position and a piperazin-1-yl group at the 11-position.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A total of 17 prioritized drugs, based on efficacy in in vitro screens, were chosen for further evaluation in a murine model of pneumonic plague to delineate if in vitro efficacy could be translated in vivo Three drugs, doxapram (DXP), amoxapine (AXPN), and trifluoperazine (TFP), increased animal survivability despite not exhibiting any direct bacteriostatic or bactericidal effect on Y." | 3.83 | New Role for FDA-Approved Drugs in Combating Antibiotic-Resistant Bacteria. ( Andersson, JA; Chauhan, S; Chopra, AK; Dann, SM; Fitts, EC; Kirtley, ML; Motin, VL; Peniche, AG; Ponnusamy, D; Rosenzweig, JA; Sha, J, 2016) |
| "Amoxapine has great clinical potential to be rapidly translated to human subjects for irinotecan-induced diarrhea." | 1.40 | Old drug new use--amoxapine and its metabolites as potent bacterial β-glucuronidase inhibitors for alleviating cancer drug toxicity. ( Ahmad, S; Kong, R; Liu, T; Phan, AT; Scott, JE; Williams, AL; Wong, ST; Yeh, LA; Zhao, H; Zhu, X, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Kong, R | 1 |
| Liu, T | 1 |
| Zhu, X | 1 |
| Ahmad, S | 1 |
| Williams, AL | 1 |
| Phan, AT | 1 |
| Zhao, H | 1 |
| Scott, JE | 1 |
| Yeh, LA | 1 |
| Wong, ST | 1 |
| Andersson, JA | 1 |
| Fitts, EC | 1 |
| Kirtley, ML | 1 |
| Ponnusamy, D | 1 |
| Peniche, AG | 1 |
| Dann, SM | 1 |
| Motin, VL | 1 |
| Chauhan, S | 1 |
| Rosenzweig, JA | 1 |
| Sha, J | 1 |
| Chopra, AK | 1 |
| Takamori, K | 1 |
| Yoshida, S | 1 |
| Okuyama, S | 1 |
5 other studies available for amoxapine and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Old drug new use--amoxapine and its metabolites as potent bacterial β-glucuronidase inhibitors for alleviating cancer drug toxicity.
Topics: Amoxapine; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Lin | 2014 |
New Role for FDA-Approved Drugs in Combating Antibiotic-Resistant Bacteria.
Topics: Amoxapine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Clostridioides difficile | 2016 |
Availability of learned helplessness test as a model of depression compared to a forced swimming test in rats.
Topics: Amoxapine; Animals; Antidepressive Agents; Behavior, Animal; Clomipramine; Depression; Disease Model | 2001 |