amoxapine has been researched along with Depressive Disorder, Major in 2 studies
Amoxapine: The N-demethylated derivative of the antipsychotic agent LOXAPINE that works by blocking the reuptake of norepinephrine, serotonin, or both; it also blocks dopamine receptors. Amoxapine is used for the treatment of depression.
amoxapine : A dibenzooxazepine compound having a chloro substituent at the 2-position and a piperazin-1-yl group at the 11-position.
Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amoxapine, a tricyclic dibenzoxazepine is an antidepressant which in the dosage range of 150-300 mg/day is notable for its rapid onset of action." | 2.65 | Systematic studies with amoxapine, a new antidepressant. ( Ban, TA; Fujimori, M; Petrie, WM; Ragheb, M; Wilson, WH, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ban, TA | 1 |
| Fujimori, M | 1 |
| Petrie, WM | 1 |
| Ragheb, M | 1 |
| Wilson, WH | 1 |
| Ogura, A | 1 |
| Morinobu, S | 1 |
| Kawakatsu, S | 1 |
| Totsuka, S | 1 |
| Komatani, A | 1 |
1 trial available for amoxapine and Depressive Disorder, Major
| Article | Year |
|---|---|
Systematic studies with amoxapine, a new antidepressant.
Topics: Adult; Amitriptyline; Amoxapine; Bipolar Disorder; Clinical Trials as Topic; Depressive Disorder; De | 1982 |
1 other study available for amoxapine and Depressive Disorder, Major
| Article | Year |
|---|---|
Changes in regional brain activity in major depression after successful treatment with antidepressant drugs.
Topics: Adult; Amoxapine; Antidepressive Agents, Tricyclic; Brain; Cerebral Cortex; Clomipramine; Depressive | 1998 |