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amoxapine and Depressive Disorder, Major

amoxapine has been researched along with Depressive Disorder, Major in 2 studies

Amoxapine: The N-demethylated derivative of the antipsychotic agent LOXAPINE that works by blocking the reuptake of norepinephrine, serotonin, or both; it also blocks dopamine receptors. Amoxapine is used for the treatment of depression.
amoxapine : A dibenzooxazepine compound having a chloro substituent at the 2-position and a piperazin-1-yl group at the 11-position.

Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)

Research Excerpts

ExcerptRelevanceReference
"Amoxapine, a tricyclic dibenzoxazepine is an antidepressant which in the dosage range of 150-300 mg/day is notable for its rapid onset of action."2.65Systematic studies with amoxapine, a new antidepressant. ( Ban, TA; Fujimori, M; Petrie, WM; Ragheb, M; Wilson, WH, 1982)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ban, TA1
Fujimori, M1
Petrie, WM1
Ragheb, M1
Wilson, WH1
Ogura, A1
Morinobu, S1
Kawakatsu, S1
Totsuka, S1
Komatani, A1

Trials

1 trial available for amoxapine and Depressive Disorder, Major

ArticleYear
Systematic studies with amoxapine, a new antidepressant.
    International pharmacopsychiatry, 1982, Volume: 17, Issue:1

    Topics: Adult; Amitriptyline; Amoxapine; Bipolar Disorder; Clinical Trials as Topic; Depressive Disorder; De

1982

Other Studies

1 other study available for amoxapine and Depressive Disorder, Major

ArticleYear
Changes in regional brain activity in major depression after successful treatment with antidepressant drugs.
    Acta psychiatrica Scandinavica, 1998, Volume: 98, Issue:1

    Topics: Adult; Amoxapine; Antidepressive Agents, Tricyclic; Brain; Cerebral Cortex; Clomipramine; Depressive

1998