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amoxapine and Bipolar Disorder

amoxapine has been researched along with Bipolar Disorder in 12 studies

Amoxapine: The N-demethylated derivative of the antipsychotic agent LOXAPINE that works by blocking the reuptake of norepinephrine, serotonin, or both; it also blocks dopamine receptors. Amoxapine is used for the treatment of depression.
amoxapine : A dibenzooxazepine compound having a chloro substituent at the 2-position and a piperazin-1-yl group at the 11-position.

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research Excerpts

ExcerptRelevanceReference
"Amitriptyline was the most effective with regard to symptoms included in the factor Sleep Disturbances and-secondary maybe-towards some items included in the factor Somatization."6.65Amoxapine versus amitriptyline in endogenous depression. A double-blind study. ( Fruensgaard, K; Hansen, CE; Korsgaard, S; Nymgaard, K; Vaag, UH, 1979)
"Amoxapine is a second-generation antidepressant possessing significant dopamine-blocking activity and extra-pyramidal side effects."5.28Amoxapine-induced neuroleptic malignant syndrome. ( Madakasira, S, 1989)
"Amoxapine, a tricyclic dibenzoxazepine is an antidepressant which in the dosage range of 150-300 mg/day is notable for its rapid onset of action."2.65Systematic studies with amoxapine, a new antidepressant. ( Ban, TA; Fujimori, M; Petrie, WM; Ragheb, M; Wilson, WH, 1982)
"Amitriptyline was the most effective with regard to symptoms included in the factor Sleep Disturbances and-secondary maybe-towards some items included in the factor Somatization."2.65Amoxapine versus amitriptyline in endogenous depression. A double-blind study. ( Fruensgaard, K; Hansen, CE; Korsgaard, S; Nymgaard, K; Vaag, UH, 1979)
"Amoxapine is a second-generation antidepressant possessing significant dopamine-blocking activity and extra-pyramidal side effects."1.28Amoxapine-induced neuroleptic malignant syndrome. ( Madakasira, S, 1989)
"A case of nonketotic hyperglycemic coma associated with the recent introduction of loxapine is presented."1.27Nonketotic hyperglycemia associated with loxapine and amoxapine: case report. ( Lesar, T; Tollefson, G, 1983)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199011 (91.67)18.7374
1990's1 (8.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Signer, SF1
Billings, RF1
Anton, RF1
Sexauer, JD1
Randall, CL1
Tollefson, G1
Lesar, T1
Weller, RA1
McKnelly, WV1
Ban, TA1
Fujimori, M1
Petrie, WM1
Ragheb, M1
Wilson, WH1
Barton, JL1
Smith, RS1
Ayd, FJ1
Rothschild, AJ1
Samson, JA1
Bessette, MP1
Carter-Campbell, JT1
Fruensgaard, K1
Hansen, CE1
Korsgaard, S1
Nymgaard, K1
Vaag, UH1
Hekimian, LJ1
Friedhoff, AJ1
Deever, E1
Madakasira, S1
D'Mello, DA1
Nasrallah, HA1

Trials

4 trials available for amoxapine and Bipolar Disorder

ArticleYear
Systematic studies with amoxapine, a new antidepressant.
    International pharmacopsychiatry, 1982, Volume: 17, Issue:1

    Topics: Adult; Amitriptyline; Amoxapine; Bipolar Disorder; Clinical Trials as Topic; Depressive Disorder; De

1982
Efficacy of the combination of fluoxetine and perphenazine in the treatment of psychotic depression.
    The Journal of clinical psychiatry, 1993, Volume: 54, Issue:9

    Topics: Adult; Amoxapine; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Bipolar Disorder; Depressi

1993
Amoxapine versus amitriptyline in endogenous depression. A double-blind study.
    Acta psychiatrica Scandinavica, 1979, Volume: 59, Issue:5

    Topics: Adult; Aged; Amitriptyline; Amoxapine; Bipolar Disorder; Blood Pressure; Body Weight; Clinical Trial

1979
A comparison of the onset of action and therapeutic efficacy of amoxapine and amitriptyline.
    The Journal of clinical psychiatry, 1978, Volume: 39, Issue:7

    Topics: Adolescent; Adult; Aged; Amitriptyline; Amoxapine; Bipolar Disorder; Depression; Dibenzoxazepines; D

1978

Other Studies

8 other studies available for amoxapine and Bipolar Disorder

ArticleYear
Amoxapine failure--a neuroleptic property?
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1984, Volume: 29, Issue:6

    Topics: Adult; Aged; Amoxapine; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Dibenzoxazepine

1984
Amoxapine elevates serum prolactin in depressed men.
    Journal of affective disorders, 1983, Volume: 5, Issue:4

    Topics: Amoxapine; Bipolar Disorder; Depressive Disorder; Desipramine; Dibenzoxazepines; Humans; Male; Middl

1983
Nonketotic hyperglycemia associated with loxapine and amoxapine: case report.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:9

    Topics: Amoxapine; Bipolar Disorder; Diabetic Coma; Dibenzoxazepines; Female; Humans; Hyperglycemic Hyperosm

1983
Case report of withdrawal dyskinesia associated with amoxapine.
    The American journal of psychiatry, 1983, Volume: 140, Issue:11

    Topics: Amoxapine; Bipolar Disorder; Dibenzoxazepines; Dyskinesia, Drug-Induced; Female; Humans; Middle Aged

1983
Amoxapine-induced agitation among bipolar depressed patients.
    The American journal of psychiatry, 1982, Volume: 139, Issue:3

    Topics: Akathisia, Drug-Induced; Amoxapine; Bipolar Disorder; Dibenzoxazepines; Humans

1982
A critical appraisal of amoxapine.
    The Journal of clinical psychiatry, 1981, Volume: 42, Issue:6

    Topics: Adult; Amoxapine; Bipolar Disorder; Depressive Disorder; Dibenzoxazepines; Drug Administration Sched

1981
Amoxapine-induced neuroleptic malignant syndrome.
    DICP : the annals of pharmacotherapy, 1989, Volume: 23, Issue:1

    Topics: Amoxapine; Bipolar Disorder; Dibenzoxazepines; Female; Humans; Middle Aged; Neuroleptic Malignant Sy

1989
Suppression of tardive dyskinesia with amoxapine: case report.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:3

    Topics: Amoxapine; Bipolar Disorder; Dibenzoxazepines; Dyskinesia, Drug-Induced; Female; Humans; Middle Aged

1986