Page last updated: 2024-08-23

amonafide and Lung Neoplasms

amonafide has been researched along with Lung Neoplasms in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's4 (40.00)18.2507
2000's3 (30.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, Z; Qian, X; Yang, Q3
Wang, C; Wang, Y; Xie, S; Zhang, X; Zhao, J1
Li, M; Wang, C; Wang, Y; Xie, S; Zhang, J1
Ebbert, LP; Foley, JF; Gesme, DH; Hatfield, AK; Jett, JR; Krook, JE; Mailliard, JA; Maksymiuk, AW; Schreffler, DD; Su, JQ1
Blum, R; Bonomi, P; Chang, AY; Smith, JL; Smith, TJ; Tu, ZN; Wiernik, PH1
Berger, MZ; Dimaggio, JJ; Gralla, RJ; Heelan, RT; Kris, MG; Marks, LD; Potanovich, LM1
Ayoub, J; Cormier, Y; Eisenhauer, EA; Evans, WK; Laberge, F; Shepherd, FA; Wierzbicki, R1
Craig, JB; Hardy, J; Harman, G; Havlin, K; Koeller, J; Kuhn, JG; Melink, TJ; Phillips, J; Saez, R; Weiss, GR1

Trials

3 trial(s) available for amonafide and Lung Neoplasms

ArticleYear
A randomized phase II trial of amonafide or trimetrexate in patients with advanced non-small cell lung cancer. A trial of the North Central Cancer Treatment Group.
    Cancer, 1993, May-01, Volume: 71, Issue:9

    Topics: Adenine; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Administration Schedule; Female; Humans; Imides; Isoquinolines; Lung Neoplasms; Male; Middle Aged; Naphthalimides; Neoplasm Staging; Organophosphonates; Trimetrexate

1993
Phase II trial of gallium nitrate, amonafide and teniposide in metastatic non-small cell lung cancer. An Eastern Cooperative Oncology Group study (E2588).
    Investigational new drugs, 1995, Volume: 13, Issue:2

    Topics: Adenine; Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drugs, Investigational; Female; Gallium; Humans; Imides; Infusions, Intravenous; Isoquinolines; Longitudinal Studies; Lung Neoplasms; Male; Middle Aged; Naphthalimides; Organophosphonates; Survival Rate; Teniposide

1995
Phase I clinical investigation of amonafide.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1989, Volume: 7, Issue:9

    Topics: Adenine; Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Chromatography, High Pressure Liquid; Clinical Trials as Topic; Drug Evaluation; Female; Half-Life; Humans; Imides; Isoquinolines; Lung Neoplasms; Male; Metabolic Clearance Rate; Middle Aged; Naphthalimides; Organophosphonates; Prostatic Neoplasms

1989

Other Studies

7 other study(ies) available for amonafide and Lung Neoplasms

ArticleYear
Synthesis, antitumor evaluation and DNA photocleaving activity of novel methylthiazonaphthalimides with aminoalkyl side chains.
    Bioorganic & medicinal chemistry letters, 2005, Jun-15, Volume: 15, Issue:12

    Topics: Animals; Antineoplastic Agents; Cattle; DNA; Drug Screening Assays, Antitumor; Humans; Imides; Inhibitory Concentration 50; Intercalating Agents; Leukemia P388; Lung Neoplasms; Mice; Naphthalenes; Radiation-Sensitizing Agents; Structure-Activity Relationship; Superoxides; Tumor Cells, Cultured; Ultraviolet Rays

2005
Highly efficient antitumor agents of heterocycles containing sulfur atom: linear and angular thiazonaphthalimides against human lung cancer cell in vitro.
    Bioorganic & medicinal chemistry, 2007, Nov-01, Volume: 15, Issue:21

    Topics: Antineoplastic Agents; Cell Line, Tumor; Heterocyclic Compounds; Humans; Lung Neoplasms; Naphthalimides; Structure-Activity Relationship; Sulfur Compounds

2007
Nonhematotoxic naphthalene diimide modified by polyamine: synthesis and biological evaluation.
    Journal of medicinal chemistry, 2012, Apr-12, Volume: 55, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Imides; Lung Neoplasms; Mice; Naphthalenes; Neoplasm Transplantation; Polyamines; Structure-Activity Relationship; Transplantation, Heterologous

2012
Synthesis and evaluation of novel amonafide-polyamine conjugates as anticancer agents.
    Chemical biology & drug design, 2017, Volume: 89, Issue:5

    Topics: Adenine; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Microscopy, Fluorescence; Naphthalimides; Neoplasms; Organophosphonates; Polyamines; Transplantation, Heterologous

2017
Novel thiazonaphthalimides as efficient antitumor and DNA photocleaving agents: effects of intercalation, side chains, and substituent groups.
    Bioorganic & medicinal chemistry, 2005, Aug-15, Volume: 13, Issue:16

    Topics: Adenine; Animals; Antineoplastic Agents; Cattle; Cell Line, Tumor; DNA; DNA, Superhelical; Drug Screening Assays, Antitumor; Humans; Imides; Intercalating Agents; Isoquinolines; Leukemia P388; Lung Neoplasms; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Naphthalenes; Naphthalimides; Organophosphonates; Phthalimides; Structure-Activity Relationship; Thiadiazines; Ultraviolet Rays

2005
Phase II trial of amonafide in patients with stage III and IV non-small-cell lung cancer.
    American journal of clinical oncology, 1991, Volume: 14, Issue:2

    Topics: Adenine; Adenocarcinoma; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Evaluation; Drug Tolerance; Female; Humans; Imides; Intercalating Agents; Isoquinolines; Lung Neoplasms; Male; Middle Aged; Naphthalimides; Neoplasm Staging; Organophosphonates; Remission Induction

1991
Phase II study of amonafide: results of treatment and lessons learned from the study of an investigational agent in previously untreated patients with extensive small-cell lung cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:3

    Topics: Adenine; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Clinical Protocols; Drug Evaluation; Drugs, Investigational; Female; Humans; Imides; Infusions, Intravenous; Isoquinolines; Lung Neoplasms; Male; Middle Aged; Naphthalimides; Organophosphonates

1990