Page last updated: 2024-08-23

amonafide and Benign Neoplasms

amonafide has been researched along with Benign Neoplasms in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's3 (33.33)18.2507
2000's2 (22.22)29.6817
2010's2 (22.22)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Cheng, CC; Zee-Cheng, RK1
Li, Y; Liu, J; Qian, X; Xu, Y; Yin, H1
Chen, Y; Ding, J; He, Q; Li, XH; Miao, ZH; Wang, YQ; Xie, YY; Yang, CH1
Huang, RZ; Jiang, H; Liang, GB; Qin, JT; Wang, HL; Wang, HS; Wei, JH; Zhang, Y1
Li, M; Wang, C; Wang, Y; Xie, S; Zhang, J1
Berezin, F; Janisch, L; Lane, LB; Mick, R; Ratain, MJ; Schilsky, RL; Vogelzang, NJ1
Akerman, S; Allen, SL; Budman, DR; Calabro, A; Chan, K; Fusco, D; Hock, K; Kreis, W; Mittelman, A; Puccio, C; Spigelman, M1
Alberts, DS; Dorr, RT; Hersh, EM; Liddil, JD; Remers, W; Sami, SM1
Diasio, RB; Stagg, MP1

Reviews

1 review(s) available for amonafide and Benign Neoplasms

ArticleYear
Novel chemotherapeutic agents in early clinical development.
    Current opinion in oncology, 1990, Volume: 2, Issue:6

    Topics: Adenine; Alkaloids; Anthraquinones; Antineoplastic Agents; Biphenyl Compounds; Camptothecin; Humans; Imides; Irinotecan; Isoquinolines; Naphthalimides; Neoplasms; Organophosphonates; Paclitaxel; Pyrazoles; Quinazolines; Sulfonylurea Compounds; Terpenes; Trimetrexate

1990

Trials

3 trial(s) available for amonafide and Benign Neoplasms

ArticleYear
Phase I study of amonafide dosing based on acetylator phenotype.
    Cancer research, 1993, May-15, Volume: 53, Issue:10 Suppl

    Topics: Acetylation; Adenine; Adult; Aged; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Humans; Imides; Intercalating Agents; Isoquinolines; Lymphoma; Male; Middle Aged; Models, Biological; Naphthalimides; Neoplasms; Organophosphonates; Phenotype

1993
Clinical pharmacokinetics of amonafide (NSC 308847) in 62 patients.
    Cancer investigation, 1996, Volume: 14, Issue:4

    Topics: Adenine; Adult; Aged; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Imides; Isoquinolines; Male; Mathematics; Metabolic Clearance Rate; Middle Aged; Models, Biological; Naphthalimides; Neoplasms; Organophosphonates; Polymorphism, Genetic

1996
Novel chemotherapeutic agents in early clinical development.
    Current opinion in oncology, 1990, Volume: 2, Issue:6

    Topics: Adenine; Alkaloids; Anthraquinones; Antineoplastic Agents; Biphenyl Compounds; Camptothecin; Humans; Imides; Irinotecan; Isoquinolines; Naphthalimides; Neoplasms; Organophosphonates; Paclitaxel; Pyrazoles; Quinazolines; Sulfonylurea Compounds; Terpenes; Trimetrexate

1990

Other Studies

6 other study(ies) available for amonafide and Benign Neoplasms

ArticleYear
N-(Aminoalkyl)imide antineoplastic agents. Synthesis and biological activity.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:9

    Topics: Adenocarcinoma; Animals; Chemical Phenomena; Chemistry; Colonic Neoplasms; Humans; Imides; Leukemia L1210; Leukemia P388; Melanoma; Neoplasms; Structure-Activity Relationship

1985
Novel N-oxide of naphthalimides as prodrug leads against hypoxic solid tumor: synthesis and biological evaluation.
    Bioorganic & medicinal chemistry letters, 2007, Apr-15, Volume: 17, Issue:8

    Topics: Antineoplastic Agents; Cell Hypoxia; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Naphthalimides; Neoplasms; Oxides; Prodrugs; Structure-Activity Relationship

2007
Design, synthesis and biological evaluation of substituted 11H-benzo[a]carbazole-5-carboxamides as novel antitumor agents.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:12

    Topics: Amides; Animals; Antineoplastic Agents; Carbazoles; Cell Cycle Checkpoints; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Mice; Mice, Nude; Neoplasms; Structure-Activity Relationship

2011
Design, synthesis and antitumor evaluation of new 1,8-naphthalimide derivatives targeting nuclear DNA.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; DNA Damage; Drug Design; Humans; Mice, Nude; Naphthalimides; Neoplasms

2021
Synthesis and evaluation of novel amonafide-polyamine conjugates as anticancer agents.
    Chemical biology & drug design, 2017, Volume: 89, Issue:5

    Topics: Adenine; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Microscopy, Fluorescence; Naphthalimides; Neoplasms; Organophosphonates; Polyamines; Transplantation, Heterologous

2017
Preclinical antitumor activity of the azonafide series of anthracene-based DNA intercalators.
    Anti-cancer drugs, 2001, Volume: 12, Issue:3

    Topics: Adenine; Animals; Antineoplastic Agents; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Humans; Imides; Intercalating Agents; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Naphthalimides; Neoplasms; Organophosphonates; Tumor Cells, Cultured; Tumor Stem Cell Assay

2001