amodiaquine has been researched along with Pyrexia in 19 studies
Amodiaquine: A 4-aminoquinoline compound with anti-inflammatory properties.
amodiaquine : A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The Home Management of Malaria (HMM) strategy was developed using chloroquine, a now obsolete drug, which has been replaced by artemisinin-based combination therapy (ACT) in health facility settings." | 9.13 | Feasibility and acceptability of artemisinin-based combination therapy for the home management of malaria in four African sites. ( Agyei-Baffour, P; Ajayi, IO; Balyeku, A; Bateganya, F; Browne, EN; Cousens, S; Doamekpor, L; Garshong, B; Munguti, K; Pagnoni, F; Yusuf, B, 2008) |
| "In 2003, artesunate-amodiaquine (AS+AQ) was introduced as the new first-line treatment for uncomplicated malaria in Burundi." | 7.74 | Community coverage of an antimalarial combination of artesunate and amodiaquine in Makamba Province, Burundi, nine months after its introduction. ( Brasher, C; Checchi, F; Cohuet, S; Edoh, K; Gerstl, S; Guthmann, JP; Lesage, A, 2007) |
| "The safety and efficacy of the two most widely used fixed-dose artemisinin-based combination therapies (ACT), artesunate-amodiaquine (ASAQ) and artemether-lumefantrine (AL) are well established for single episodes of uncomplicated Plasmodium falciparum malaria, but the effects of repeated, long-term use are not well documented." | 5.19 | Efficacy and safety of fixed-dose artesunate-amodiaquine vs. artemether-lumefantrine for repeated treatment of uncomplicated malaria in Ugandan children. ( Afizi, K; Fredrick, M; Kamya, MR; Lameyre, V; Lukwago, R; Talisuna, AO; Yeka, A, 2014) |
| "Community health workers in Dangme-West district, Ghana, treated children aged 2-59 months with fever with either artesunate-amodiaquine (AAQ) or AAQ plus amoxicillin (AAQ + AMX) within a cluster-randomized controlled trial (registration no." | 5.17 | Impact of treating young children with antimalarials with or without antibiotics on morbidity: a cluster-randomized controlled trial in Ghana. ( Abbey, M; Adjuik, M; Chinbuah, MA; Cobelens, F; Gyapong, JO; Gyapong, M; Kager, PA; Koram, KA, 2013) |
| "The Home Management of Malaria (HMM) strategy was developed using chloroquine, a now obsolete drug, which has been replaced by artemisinin-based combination therapy (ACT) in health facility settings." | 5.13 | Feasibility and acceptability of artemisinin-based combination therapy for the home management of malaria in four African sites. ( Agyei-Baffour, P; Ajayi, IO; Balyeku, A; Bateganya, F; Browne, EN; Cousens, S; Doamekpor, L; Garshong, B; Munguti, K; Pagnoni, F; Yusuf, B, 2008) |
| "The study examined the efficacy of chloroquine (CQ), amodiaquine (AQ) and sulphadoxine-pyrimethamine (SP) for the treatment of uncomplicated Plasmodium falciparum malaria in Ghana." | 5.11 | A randomized comparative study of chloroquine, amodiaquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated malaria in Ghana. ( Amankwa, J; Ansah, NA; Ansah, P; Anto, F; Anyorigiya, T; Atuguba, F; Hodgson, A; Mumuni, G; Oduro, AR, 2005) |
| "We conducted two randomized clinical trials to determine the in vivo efficacy of amodiaquine and sulfadoxine/pyrimethamine in treating Plasmodium falciparum malaria." | 5.09 | In vivo efficacy study of amodiaquine and sulfadoxine/ pyrimethamine in Kibwezi, Kenya and Kigoma, Tanzania. ( Ashruf, G; Bennebroek, J; Gikunda, S; Gorissen, E; Kager, PA; Lamboo, M; Mbaruku, G, 2000) |
| " MRDT-positive children received artesunate-amodiaquine (ASAQ), while MRDT-negative children were treated based on the clinical diagnosis of non-malaria febrile illness." | 3.91 | Consequences of restricting antimalarial drugs to rapid diagnostic test-positive febrile children in south-west Nigeria. ( Ajayi, IO; Baba, E; Badejo, JA; Chandramohan, D; Dada-Adegbola, HO; Falade, CO; Funwei, RI; Hamade, P; Jegede, AS; Michael, OS; Ogunkunle, OO; Ojurongbe, OD; Orimadegun, AE; Ssekitooleko, J; Webster, J, 2019) |
| "In 2003, artesunate-amodiaquine (AS+AQ) was introduced as the new first-line treatment for uncomplicated malaria in Burundi." | 3.74 | Community coverage of an antimalarial combination of artesunate and amodiaquine in Makamba Province, Burundi, nine months after its introduction. ( Brasher, C; Checchi, F; Cohuet, S; Edoh, K; Gerstl, S; Guthmann, JP; Lesage, A, 2007) |
| "A village-based programme of presumptive treatment of fever, using voluntary village aides to dispense oral chloroquine or amodiaquine, was established in 1982 by the Papua New Guinea Institute of Medical Research (PNG IMR) in 35 rural villages or hamlets near Madang, on the north coast of PNG." | 3.67 | The role of voluntary village aides in the control of malaria by presumptive treatment of fever. 2. Impact on village health. ( Alpers, MP; Heywood, PF; Jolley, DJ; Moir, JS; Tulloch, JL; Vrbova, H, 1985) |
| "Malaria and pneumonia are leading causes of childhood mortality." | 2.77 | Impact of community management of fever (using antimalarials with or without antibiotics) on childhood mortality: a cluster-randomized controlled trial in Ghana. ( Abbey, M; Adjuik, M; Aikins, M; Awini, E; Chinbuah, MA; Gyapong, JO; Gyapong, M; Kager, PA; Nonvignon, J; Pagnoni, F, 2012) |
| " Adverse events and clinical and parasitological outcomes were recorded." | 2.73 | A randomised trial to assess the safety and efficacy of artemether-lumefantrine (Coartem) for the treatment of uncomplicated Plasmodium falciparum malaria in Rwanda. ( D'Alessandro, U; Fanello, CI; Karema, C; Ngamije, D; van Doren, W; Van Overmeir, C, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.53) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (47.37) | 29.6817 |
| 2010's | 7 (36.84) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Pembet Singana, B | 1 |
| Casimiro, PN | 1 |
| Matondo Diassivi, B | 1 |
| Kobawila, SC | 1 |
| Youndouka, JM | 1 |
| Basco, LK | 1 |
| Ringwald, P | 1 |
| Briolant, S | 1 |
| Ndounga, M | 1 |
| Falade, CO | 1 |
| Orimadegun, AE | 1 |
| Michael, OS | 1 |
| Dada-Adegbola, HO | 1 |
| Ogunkunle, OO | 1 |
| Badejo, JA | 1 |
| Funwei, RI | 1 |
| Ajayi, IO | 2 |
| Jegede, AS | 1 |
| Ojurongbe, OD | 1 |
| Ssekitooleko, J | 1 |
| Baba, E | 1 |
| Hamade, P | 1 |
| Webster, J | 1 |
| Chandramohan, D | 1 |
| Baba, M | 1 |
| Toyama, M | 1 |
| Sakakibara, N | 1 |
| Okamoto, M | 1 |
| Arima, N | 1 |
| Saijo, M | 1 |
| Munyangi, J | 1 |
| Cornet-Vernet, L | 1 |
| Idumbo, M | 1 |
| Lu, C | 1 |
| Lutgen, P | 1 |
| Perronne, C | 1 |
| Ngombe, N | 1 |
| Bianga, J | 1 |
| Mupenda, B | 1 |
| Lalukala, P | 1 |
| Mergeai, G | 1 |
| Mumba, D | 1 |
| Towler, M | 1 |
| Weathers, P | 1 |
| Bisoffi, Z | 1 |
| Tinto, H | 1 |
| Sirima, BS | 1 |
| Gobbi, F | 1 |
| Angheben, A | 1 |
| Buonfrate, D | 1 |
| Van den Ende, J | 1 |
| Chinbuah, MA | 2 |
| Adjuik, M | 2 |
| Cobelens, F | 1 |
| Koram, KA | 2 |
| Abbey, M | 2 |
| Gyapong, M | 2 |
| Kager, PA | 3 |
| Gyapong, JO | 2 |
| Yeka, A | 1 |
| Lameyre, V | 1 |
| Afizi, K | 1 |
| Fredrick, M | 1 |
| Lukwago, R | 1 |
| Kamya, MR | 1 |
| Talisuna, AO | 1 |
| Ahorlu, CK | 1 |
| Seakey, AK | 1 |
| Weiss, MG | 1 |
| Awini, E | 1 |
| Nonvignon, J | 1 |
| Aikins, M | 1 |
| Pagnoni, F | 2 |
| Oduro, AR | 1 |
| Anyorigiya, T | 1 |
| Hodgson, A | 1 |
| Ansah, P | 1 |
| Anto, F | 1 |
| Ansah, NA | 1 |
| Atuguba, F | 1 |
| Mumuni, G | 1 |
| Amankwa, J | 1 |
| Sowunmi, A | 1 |
| Fehintola, FA | 1 |
| Adedeji, AA | 1 |
| Gbotosho, GO | 1 |
| Tambo, E | 1 |
| Fateye, BA | 1 |
| Happi, TC | 1 |
| Oduola, AM | 1 |
| Patrick Kachur, S | 1 |
| Schulden, J | 1 |
| Goodman, CA | 1 |
| Kassala, H | 1 |
| Elling, BF | 1 |
| Khatib, RA | 1 |
| Causer, LM | 1 |
| Mkikima, S | 1 |
| Abdulla, S | 1 |
| Bloland, PB | 1 |
| Fanello, CI | 1 |
| Karema, C | 1 |
| van Doren, W | 1 |
| Van Overmeir, C | 1 |
| Ngamije, D | 1 |
| D'Alessandro, U | 1 |
| Gerstl, S | 1 |
| Cohuet, S | 1 |
| Edoh, K | 1 |
| Brasher, C | 1 |
| Lesage, A | 1 |
| Guthmann, JP | 1 |
| Checchi, F | 1 |
| Browne, EN | 1 |
| Garshong, B | 1 |
| Bateganya, F | 1 |
| Yusuf, B | 1 |
| Agyei-Baffour, P | 1 |
| Doamekpor, L | 1 |
| Balyeku, A | 1 |
| Munguti, K | 1 |
| Cousens, S | 1 |
| Gorissen, E | 1 |
| Ashruf, G | 1 |
| Lamboo, M | 1 |
| Bennebroek, J | 1 |
| Gikunda, S | 1 |
| Mbaruku, G | 1 |
| Talani, P | 1 |
| Samba, G | 1 |
| Moyen, G | 1 |
| Moir, JS | 2 |
| Tulloch, JL | 2 |
| Vrbova, H | 2 |
| Jolley, DJ | 2 |
| Heywood, PF | 2 |
| Alpers, MP | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized, Double-blind, Placebo-controlled, Multicenter, Multi-arm, Phase II Trial of Novel Agents for the Treatment of Mild to Moderate COVID-19 Positive Outpatients[NCT04530617] | Phase 2 | 246 participants (Actual) | Interventional | 2020-10-05 | Terminated (stopped due to Results from the interim analysis) | ||
| A Randomised Study to Compare a Fixed Dose Combination of Artesunate Plus Amiodaquine (Coarsucam) Versus a Fixed Dose Combination of Artemether Plus Lumefantrine (Coartem) in the Treatment of Repeated Uncomplicated Plasmodium Falciparum Malaria Attacks Oc[NCT00699920] | Phase 4 | 413 participants (Actual) | Interventional | 2008-06-30 | Completed | ||
| Exploring the Impact of Scaling up Mass Testing, Treatment and Tracking on Malaria Prevalence Among Children in the Pakro Sub District of Ghana[NCT04167566] | 5,000 participants (Actual) | Interventional | 2017-07-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 trials available for amodiaquine and Pyrexia
| Article | Year |
|---|---|
Artemisia annua and Artemisia afra tea infusions vs. artesunate-amodiaquine (ASAQ) in treating Plasmodium falciparum malaria in a large scale, double blind, randomized clinical trial.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Artemisia; Artemisia annua; Artemisinins; Child; Doub | 2019 |
Impact of treating young children with antimalarials with or without antibiotics on morbidity: a cluster-randomized controlled trial in Ghana.
Topics: Amodiaquine; Amoxicillin; Anemia; Anti-Bacterial Agents; Antimalarials; Artemisinins; Caregivers; Ch | 2013 |
Efficacy and safety of fixed-dose artesunate-amodiaquine vs. artemether-lumefantrine for repeated treatment of uncomplicated malaria in Ugandan children.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Child, Preschool; Data Collection; Drug Combin | 2014 |
Effectiveness of combined intermittent preventive treatment for children and timely home treatment for malaria control.
Topics: Adult; Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Caregivers; Child, Preschool; | 2009 |
Impact of community management of fever (using antimalarials with or without antibiotics) on childhood mortality: a cluster-randomized controlled trial in Ghana.
Topics: Amodiaquine; Amoxicillin; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antimalarials; Artemis | 2012 |
A randomized comparative study of chloroquine, amodiaquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated malaria in Ghana.
Topics: Amodiaquine; Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Female; Fever; Ghana; | 2005 |
Open randomized study of artesunate-amodiaquine vs. chloroquine-pyrimethamine-sulfadoxine for the treatment of uncomplicated Plasmodium falciparum malaria in Nigerian children.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Com | 2005 |
A randomised trial to assess the safety and efficacy of artemether-lumefantrine (Coartem) for the treatment of uncomplicated Plasmodium falciparum malaria in Rwanda.
Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschoo | 2007 |
Feasibility and acceptability of artemisinin-based combination therapy for the home management of malaria in four African sites.
Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschoo | 2008 |
In vivo efficacy study of amodiaquine and sulfadoxine/ pyrimethamine in Kibwezi, Kenya and Kigoma, Tanzania.
Topics: Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Drug Resistance, Microbial; Female; Fe | 2000 |
9 other studies available for amodiaquine and Pyrexia
| Article | Year |
|---|---|
Prevalence of malaria among febrile patients and assessment of efficacy of artemether-lumefantrine and artesunate-amodiaquine for uncomplicated malaria in Dolisie, Republic of the Congo.
Topics: Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artesunate; Child | 2022 |
Consequences of restricting antimalarial drugs to rapid diagnostic test-positive febrile children in south-west Nigeria.
Topics: Amodiaquine; Antimalarials; Artemisinins; Child, Preschool; Cross-Sectional Studies; Drug Combinatio | 2019 |
Establishment of an antiviral assay system and identification of severe fever with thrombocytopenia syndrome virus inhibitors.
Topics: Amides; Amodiaquine; Animals; Antiviral Agents; Bunyaviridae; Bunyaviridae Infections; Cell Line; Ch | 2017 |
Should malaria treatment be guided by a point of care rapid test? A threshold approach to malaria management in rural Burkina Faso.
Topics: Adult; Amodiaquine; Antimalarials; Burkina Faso; Child, Preschool; Decision Making; Drug Combination | 2013 |
Prevalence of malaria parasitemia among clients seeking treatment for fever or malaria at drug stores in rural Tanzania 2004.
Topics: Adult; Amodiaquine; Analgesics, Non-Narcotic; Anemia; Antimalarials; Child, Preschool; Drug Combinat | 2006 |
Community coverage of an antimalarial combination of artesunate and amodiaquine in Makamba Province, Burundi, nine months after its introduction.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Burundi; Child, Preschool; Community Health Se | 2007 |
[Management of child fever in the battle against malaria in Brazzaville].
Topics: Amodiaquine; Antimalarials; Asthenia; Child, Preschool; Chills; Chloroquine; Congo; Diarrhea; Fever; | 2002 |
The role of voluntary village aides in the control of malaria by presumptive treatment of fever. 1. Selection, training and practice.
Topics: Adult; Amodiaquine; Attitude to Health; Chloroquine; Community Health Workers; Female; Fever; Humans | 1985 |
The role of voluntary village aides in the control of malaria by presumptive treatment of fever. 2. Impact on village health.
Topics: Adolescent; Amodiaquine; Child; Child, Preschool; Chloroquine; Community Health Workers; Fever; Huma | 1985 |