amodiaquine has been researched along with Pregnancy in 43 studies
Amodiaquine: A 4-aminoquinoline compound with anti-inflammatory properties.
amodiaquine : A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether dihydroartemisinin-piperaquine (DHA-PPQ) is non-inferior to artesunate-amodiaquine (ASAQ) for treating uncomplicated malaria infection in pregnancy." | 9.24 | Dihydroartemisinin-piperaquine versus artesunate-amodiaquine for treatment of malaria infection in pregnancy in Ghana: an open-label, randomised, non-inferiority trial. ( Alifrangis, M; Cairns, M; Magnussen, P; Osarfo, J; Tagbor, H, 2017) |
| "To compare the artesunate-amodiaquine and artemether-lumefantrine combinations in the treatment of acute uncomplicated falciparum malaria during pregnancy." | 9.20 | A randomized trial of artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in pregnancy. ( Aboderin, O; Badejoko, O; Fatusi, A; Loto, O; Ogunniyi, S; Ukah, M, 2015) |
| "In order to study the pharmacokinetic properties of amodiaquine and desethylamodiaquine during pregnancy, 24 pregnant women in the second and third trimesters of pregnancy and with Plasmodium vivax malaria were treated with amodiaquine (10 mg/kg of body weight/day) for 3 days." | 9.15 | Pharmacokinetics of amodiaquine and desethylamodiaquine in pregnant and postpartum women with Plasmodium vivax malaria. ( Cammas, M; Hsi, P; Jullien, V; Lindegardh, N; McGready, R; Nosten, F; Phyo, AP; Rijken, MJ; Singhasivanon, P; Tarning, J; White, NJ; Win, AK, 2011) |
| "The use of artemisinin derivative-based combination therapy (ACT) such as artesunate plus amodiaquine is currently recommended for the treatment of uncomplicated Plasmodium falciparum malaria." | 9.14 | Randomized, multicentre assessment of the efficacy and safety of ASAQ--a fixed-dose artesunate-amodiaquine combination therapy in the treatment of uncomplicated Plasmodium falciparum malaria. ( Brasseur, P; Dara, N; Diallo, M; Dicko, Y; Djimde, A; Faye, B; Forlemu, D; Gaye, O; Lameyre, V; Moor, VA; Ndiaye, I; Ndiaye, JL; Randrianarivelojosia, M; Randrianasolo, L; Ratsimbasoa, A; Sagara, I; Same-Ekobo, A; Traore, A, 2009) |
| "Pregnant women with non-severe, slide proven, falciparum malaria were randomised to one of 4 regimes: sulfadoxine-pyrimethamine [SP]; chlorproguanil-dapsone [CD]; SP+amodiaquine [SP+AQ] or amodiaquine+artesunate [AQ+AS]." | 9.14 | Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania. ( Briceño, M; Drakeley, C; Greenwood, BM; Mutabingwa, TK; Muze, K; Ord, R; Whitty, CJ, 2009) |
| "Amodiaquine alone or in combination with sulphadoxine-pyrimethamine, although associated with minor side-effects, is effective when used to treat malaria in pregnancy." | 9.12 | Efficacy, safety, and tolerability of amodiaquine plus sulphadoxine-pyrimethamine used alone or in combination for malaria treatment in pregnancy: a randomised trial. ( Browne, E; Bruce, J; Chandramohan, D; Greenwood, B; Randal, A; Tagbor, H, 2006) |
| "We did a systematic review of interventional or observational cohort studies assessing the efficacy of artemisinin-based or quinine-based treatments in pregnancy." | 9.05 | Efficacy and tolerability of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: a systematic review and individual patient data meta-analysis. ( Anvikar, AR; Ashley, EA; Chandramohan, D; Cohee, LM; D'Alessandro, U; Genton, B; Gilder, ME; Guérin, PJ; Juma, E; Kalilani-Phiri, L; Kennon, K; Kuepfer, I; Laufer, MK; Lwin, KM; Mansoor, R; McGready, R; Meshnick, SR; Mosha, D; Mwapasa, V; Mwebaza, N; Nambozi, M; Ndiaye, JA; Nosten, F; Nyunt, M; Ogutu, B; Parikh, S; Paw, MK; Phyo, AP; Pimanpanarak, M; Piola, P; Rijken, MJ; Saito, M; Sriprawat, K; Stepniewska, K; Tagbor, HK; Tarning, J; Tinto, H; Valéa, I; Valecha, N; White, NJ; Wiladphaingern, J, 2020) |
| "The World Health Organization currently recommends quinine+clindamycin for use against malaria in the first trimester." | 8.95 | Animal Embryotoxicity Studies of Key Non-Artemisinin Antimalarials and Use in Women in the First Trimester. ( Clark, RL, 2017) |
| "Several African countries have begun using amodiaquine-containing combinations as first-line antimalarial treatment, with the result that a substantial number of pregnant women are likely to be exposed to amodiaquine." | 8.82 | Can amodiaquine be used safely during pregnancy? ( D'Alessandro, U; Erhart, A; Thomas, F, 2004) |
| "Artesunate-amodiaquine (ASAQ) and Artemether-lumefantrine (AL) are the recommended treatment for uncomplicated Plasmodium falciparum malaria in Liberia." | 8.12 | Artesunate-amodiaquine and artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in Liberia: in vivo efficacy and frequency of molecular markers. ( Asinya, M; Jeuronlon, MK; Kamara, P; Koko, VS; Kollie, A; Ma, L; Menard, D; Nyansaiye, P; Parwon, S; Pratt, OJ; Ringwald, P; Taweh, F; Tehmeh, L; Vonhm, B; Warsame, M, 2022) |
| "Amodiaquine is effective for the treatment of Plasmodium vivax malaria, but there is little information on the pharmacokinetic and pharmacodynamic properties of amodiaquine in pregnant women with malaria." | 7.78 | Population pharmacokinetic and pharmacodynamic modeling of amodiaquine and desethylamodiaquine in women with Plasmodium vivax malaria during and after pregnancy. ( Bergstrand, M; Cammas, M; Chotsiri, P; Day, NP; Jullien, V; Lindegardh, N; McGready, R; Nosten, F; Rijken, MJ; Singhasivanon, P; Tarning, J; White, NJ, 2012) |
| "To determine whether dihydroartemisinin-piperaquine (DHA-PPQ) is non-inferior to artesunate-amodiaquine (ASAQ) for treating uncomplicated malaria infection in pregnancy." | 5.24 | Dihydroartemisinin-piperaquine versus artesunate-amodiaquine for treatment of malaria infection in pregnancy in Ghana: an open-label, randomised, non-inferiority trial. ( Alifrangis, M; Cairns, M; Magnussen, P; Osarfo, J; Tagbor, H, 2017) |
| " Pregnant women diagnosed with malaria are randomised to receive either amodiaquine-artesunate (AQ-AS), dihydroartemisinin-piperaquine (DHA-PQ), artemether-lumefantrine (AL), or mefloquine-artesunate (MQAS)." | 5.20 | Safe and efficacious artemisinin-based combination treatments for African pregnant women with malaria: a multicentre randomized control trial. ( Claeys, Y; D'Alessandro, U; De Crop, M; Halidou, T; Kalanda, G; Menten, J; Mulenga, M; Mutabingwa, T; Mwakazanga, D; Mwapasa, V; Nambozi, M; Phiri, LK; Ravinetto, R; Schurmans, C; Tagbor, H; Thriemer, K; Traore, M; Valea, I; Van Geertruyden, JP, 2015) |
| "To compare the artesunate-amodiaquine and artemether-lumefantrine combinations in the treatment of acute uncomplicated falciparum malaria during pregnancy." | 5.20 | A randomized trial of artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in pregnancy. ( Aboderin, O; Badejoko, O; Fatusi, A; Loto, O; Ogunniyi, S; Ukah, M, 2015) |
| "In order to study the pharmacokinetic properties of amodiaquine and desethylamodiaquine during pregnancy, 24 pregnant women in the second and third trimesters of pregnancy and with Plasmodium vivax malaria were treated with amodiaquine (10 mg/kg of body weight/day) for 3 days." | 5.15 | Pharmacokinetics of amodiaquine and desethylamodiaquine in pregnant and postpartum women with Plasmodium vivax malaria. ( Cammas, M; Hsi, P; Jullien, V; Lindegardh, N; McGready, R; Nosten, F; Phyo, AP; Rijken, MJ; Singhasivanon, P; Tarning, J; White, NJ; Win, AK, 2011) |
| "Pregnant women with non-severe, slide proven, falciparum malaria were randomised to one of 4 regimes: sulfadoxine-pyrimethamine [SP]; chlorproguanil-dapsone [CD]; SP+amodiaquine [SP+AQ] or amodiaquine+artesunate [AQ+AS]." | 5.14 | Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania. ( Briceño, M; Drakeley, C; Greenwood, BM; Mutabingwa, TK; Muze, K; Ord, R; Whitty, CJ, 2009) |
| "The use of artemisinin derivative-based combination therapy (ACT) such as artesunate plus amodiaquine is currently recommended for the treatment of uncomplicated Plasmodium falciparum malaria." | 5.14 | Randomized, multicentre assessment of the efficacy and safety of ASAQ--a fixed-dose artesunate-amodiaquine combination therapy in the treatment of uncomplicated Plasmodium falciparum malaria. ( Brasseur, P; Dara, N; Diallo, M; Dicko, Y; Djimde, A; Faye, B; Forlemu, D; Gaye, O; Lameyre, V; Moor, VA; Ndiaye, I; Ndiaye, JL; Randrianarivelojosia, M; Randrianasolo, L; Ratsimbasoa, A; Sagara, I; Same-Ekobo, A; Traore, A, 2009) |
| "The use of sulfadoxine-pyrimethamine (SP) for intermittent preventive treatment in pregnancy (IPTp) is threatened by the spread of resistance to SP." | 5.13 | A randomized, controlled trial of intermittent preventive treatment with sulfadoxine-pyrimethamine, amodiaquine, or the combination in pregnant women in Ghana. ( Affipunguh, PK; Bruce, J; Chandramohan, D; Clerk, CA; Greenwood, B; Hodgson, A; Mensah, N, 2008) |
| "Amodiaquine alone or in combination with sulphadoxine-pyrimethamine, although associated with minor side-effects, is effective when used to treat malaria in pregnancy." | 5.12 | Efficacy, safety, and tolerability of amodiaquine plus sulphadoxine-pyrimethamine used alone or in combination for malaria treatment in pregnancy: a randomised trial. ( Browne, E; Bruce, J; Chandramohan, D; Greenwood, B; Randal, A; Tagbor, H, 2006) |
| "In October 1988, a project was implemented for assessing the malaria chemoprophylactic efficacy of weekly chloroquine (CQ) and daily proguanil (PROG) during pregnancy in Muheza-Tanzania." | 5.07 | Malaria in infants whose mothers received chemoprophylaxis: response to amodiaquine therapy. ( de Geus, A; Malle, LN; Mutabingwa, TK; Wernsdorfer, WH, 1992) |
| "We did a systematic review of interventional or observational cohort studies assessing the efficacy of artemisinin-based or quinine-based treatments in pregnancy." | 5.05 | Efficacy and tolerability of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: a systematic review and individual patient data meta-analysis. ( Anvikar, AR; Ashley, EA; Chandramohan, D; Cohee, LM; D'Alessandro, U; Genton, B; Gilder, ME; Guérin, PJ; Juma, E; Kalilani-Phiri, L; Kennon, K; Kuepfer, I; Laufer, MK; Lwin, KM; Mansoor, R; McGready, R; Meshnick, SR; Mosha, D; Mwapasa, V; Mwebaza, N; Nambozi, M; Ndiaye, JA; Nosten, F; Nyunt, M; Ogutu, B; Parikh, S; Paw, MK; Phyo, AP; Pimanpanarak, M; Piola, P; Rijken, MJ; Saito, M; Sriprawat, K; Stepniewska, K; Tagbor, HK; Tarning, J; Tinto, H; Valéa, I; Valecha, N; White, NJ; Wiladphaingern, J, 2020) |
| "The World Health Organization currently recommends quinine+clindamycin for use against malaria in the first trimester." | 4.95 | Animal Embryotoxicity Studies of Key Non-Artemisinin Antimalarials and Use in Women in the First Trimester. ( Clark, RL, 2017) |
| " Chemopreventive strategies have been increasingly deployed in Africa, notably intermittent sulfadoxine-pyrimethamine treatment in pregnancy, and monthly amodiaquine-sulfadoxine-pyrimethamine during the rainy season months in children aged between 3 months and 5 years across the sub-Sahel." | 4.90 | Malaria. ( Dondorp, AM; Faiz, MA; Hien, TT; Mokuolu, OA; Pukrittayakamee, S; White, NJ, 2014) |
| "Several African countries have begun using amodiaquine-containing combinations as first-line antimalarial treatment, with the result that a substantial number of pregnant women are likely to be exposed to amodiaquine." | 4.82 | Can amodiaquine be used safely during pregnancy? ( D'Alessandro, U; Erhart, A; Thomas, F, 2004) |
| "Artesunate-amodiaquine (ASAQ) and Artemether-lumefantrine (AL) are the recommended treatment for uncomplicated Plasmodium falciparum malaria in Liberia." | 4.12 | Artesunate-amodiaquine and artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in Liberia: in vivo efficacy and frequency of molecular markers. ( Asinya, M; Jeuronlon, MK; Kamara, P; Koko, VS; Kollie, A; Ma, L; Menard, D; Nyansaiye, P; Parwon, S; Pratt, OJ; Ringwald, P; Taweh, F; Tehmeh, L; Vonhm, B; Warsame, M, 2022) |
| " This study aimed to monitor the occurrence of adverse events (AEs) after the use of artemisinin-based combination therapies (ACTs), identify potential drivers of reporting suspected adverse drug reactions (ADRs) and monitor AEs among women who were inadvertently exposed to ACTs in the first trimester of pregnancy." | 3.96 | Optimal Approach and Strategies to Strengthen Pharmacovigilance in Sub-Saharan Africa: A Cohort Study of Patients Treated with First-Line Artemisinin-Based Combination Therapies in the Nanoro Health and Demographic Surveillance System, Burkina Faso. ( Bihoun, B; Derra, K; Kazienga, A; Nakanabo-Diallo, S; Pagnoni, F; Rouamba, E; Rouamba, T; Samadoulougou-Kirakoya, F; Sondo, P; Sorgho, H; Tarnagda, Z; Tinto, H; Valea, I, 2020) |
| "A pilot programme of Cohort Event Monitoring (CEM) was conducted across the six geopolitical zones of Nigeria on patients treated for uncomplicated malaria with artemisinin-based combination therapy (ACT)." | 3.79 | Safety of Artemisinin-Based Combination Therapies in Nigeria: A Cohort Event Monitoring Study. ( Adesina, O; Bassi, PU; Coulter, D; Isah, A; Jalo, I; Kalat, M; Nwoasu, SC; Nyong, EE; Osakwe, AI; Osungwu, F; Pal, S; Suku, C; Ugochukwu, C; Wallberg, M; Wammanda, RD, 2013) |
| "Amodiaquine is effective for the treatment of Plasmodium vivax malaria, but there is little information on the pharmacokinetic and pharmacodynamic properties of amodiaquine in pregnant women with malaria." | 3.78 | Population pharmacokinetic and pharmacodynamic modeling of amodiaquine and desethylamodiaquine in women with Plasmodium vivax malaria during and after pregnancy. ( Bergstrand, M; Cammas, M; Chotsiri, P; Day, NP; Jullien, V; Lindegardh, N; McGready, R; Nosten, F; Rijken, MJ; Singhasivanon, P; Tarning, J; White, NJ, 2012) |
| "After adoption of artesunate-amodiaquine (AS/AQ) as first-line therapy for the treatment of uncomplicated malaria by the malaria control programme, this study was designed to assess the availability of anti-malarial drugs, treatment practices and acceptability of the new protocol by health professionals, in the urban health facilities and drugstores of Yaoundé city, Cameroon." | 3.75 | Treatment of malaria from monotherapy to artemisinin-based combination therapy by health professionals in urban health facilities in Yaoundé, central province, Cameroon. ( Bley, D; Gausseres, M; Malvy, D; Millet, P; Sayang, C; Vernazza-Licht, N, 2009) |
| " Understanding the safety, pharmacokinetic and pharmacodynamic properties of antimalarial combination therapies is crucial in optimising dosing." | 2.82 | Pharmacokinetic considerations in seasonal malaria chemoprevention. ( Chotsiri, P; Tarning, J; White, NJ, 2022) |
| " Additionally, these models are able to identify patient characteristics that cause alterations in the expected PK/PD profiles and through simulations can recommend changes to dosing which compensate for the differences." | 2.72 | Malaria PK/PD and the Role Pharmacometrics Can Play in the Global Health Arena: Malaria Treatment Regimens for Vulnerable Populations. ( Hughes, E; Jagannathan, P; Mohamed Ali, A; Savic, RM; Wallender, E, 2021) |
| " However, increasing Plasmodium falciparum resistance to chloroquine and sulfadoxine-pyrimethamine makes finding alternative antimalarials that are safe and effective in pregnancy a priority." | 2.44 | The safety of amodiaquine use in pregnant women. ( Chandramohan, D; Greenwood, B; Tagbor, HK, 2007) |
| "Malaria is not a disease of the past." | 2.36 | [Current information on treatment and prophylaxis of malaria (author's transl)]. ( Cambournac, FJ, 1979) |
| " Reappraisal of quinine therapy has led to important modifications in dosage recommendations and recognition of a major complication of severe malaria associated with its use--hypoglycaemia." | 1.27 | Management of Plasmodium falciparum malaria. ( Phillips, RE, 1984) |
| "Chloroquine resistance was confirmed by testing in vitro and in vivo." | 1.27 | Multiple drug resistant Plasmodium falciparum malaria in a pregnant indigenous Zambian woman. ( Rolfe, M, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (27.91) | 18.7374 |
| 1990's | 1 (2.33) | 18.2507 |
| 2000's | 11 (25.58) | 29.6817 |
| 2010's | 11 (25.58) | 24.3611 |
| 2020's | 8 (18.60) | 2.80 |
| Authors | Studies |
|---|---|
| Dentinger, CM | 1 |
| Rakotomanga, TA | 1 |
| Rakotondrandriana, A | 1 |
| Rakotoarisoa, A | 1 |
| Rason, MA | 1 |
| Moriarty, LF | 1 |
| Steinhardt, LC | 1 |
| Kapesa, L | 1 |
| Razafindrakoto, J | 1 |
| Svigel, SS | 1 |
| Lucchi, NW | 1 |
| Udhayakumar, V | 1 |
| Halsey, ES | 1 |
| Ratsimbasoa, CA | 1 |
| Koko, VS | 1 |
| Warsame, M | 2 |
| Vonhm, B | 1 |
| Jeuronlon, MK | 1 |
| Menard, D | 2 |
| Ma, L | 1 |
| Taweh, F | 1 |
| Tehmeh, L | 1 |
| Nyansaiye, P | 1 |
| Pratt, OJ | 1 |
| Parwon, S | 1 |
| Kamara, P | 1 |
| Asinya, M | 1 |
| Kollie, A | 1 |
| Ringwald, P | 1 |
| Chotsiri, P | 2 |
| White, NJ | 5 |
| Tarning, J | 4 |
| Issa, MS | 1 |
| Mahamat, MHT | 1 |
| Saleh, IDM | 1 |
| Boulotigam, K | 1 |
| Djimrassengar, H | 1 |
| Issa, AH | 1 |
| Abdelkader, O | 1 |
| Hassoumi, M | 1 |
| Djimadoum, M | 1 |
| Doderer-Lang, C | 1 |
| Ndihiokubwayo, JB | 1 |
| Rasmussen, C | 1 |
| Rouamba, T | 1 |
| Sondo, P | 1 |
| Derra, K | 1 |
| Nakanabo-Diallo, S | 1 |
| Bihoun, B | 1 |
| Rouamba, E | 1 |
| Tarnagda, Z | 1 |
| Kazienga, A | 1 |
| Valea, I | 4 |
| Sorgho, H | 1 |
| Pagnoni, F | 1 |
| Samadoulougou-Kirakoya, F | 1 |
| Tinto, H | 3 |
| Saito, M | 1 |
| Mansoor, R | 1 |
| Kennon, K | 1 |
| Anvikar, AR | 1 |
| Ashley, EA | 1 |
| Chandramohan, D | 4 |
| Cohee, LM | 1 |
| D'Alessandro, U | 5 |
| Genton, B | 1 |
| Gilder, ME | 1 |
| Juma, E | 1 |
| Kalilani-Phiri, L | 2 |
| Kuepfer, I | 1 |
| Laufer, MK | 1 |
| Lwin, KM | 1 |
| Meshnick, SR | 1 |
| Mosha, D | 1 |
| Mwapasa, V | 3 |
| Mwebaza, N | 1 |
| Nambozi, M | 3 |
| Ndiaye, JA | 1 |
| Nosten, F | 3 |
| Nyunt, M | 1 |
| Ogutu, B | 1 |
| Parikh, S | 1 |
| Paw, MK | 1 |
| Phyo, AP | 2 |
| Pimanpanarak, M | 1 |
| Piola, P | 1 |
| Rijken, MJ | 3 |
| Sriprawat, K | 1 |
| Tagbor, HK | 2 |
| Valecha, N | 1 |
| Wiladphaingern, J | 1 |
| Stepniewska, K | 1 |
| McGready, R | 3 |
| Guérin, PJ | 2 |
| Siribie, M | 1 |
| Tchouatieu, AM | 1 |
| Soulama, I | 1 |
| Kaboré, JMT | 1 |
| Nombré, Y | 1 |
| Hien, D | 1 |
| Kiba Koumaré, A | 1 |
| Barry, N | 1 |
| Baguiya, A | 1 |
| Héma, A | 1 |
| Dianda, F | 1 |
| Savadogo, Y | 1 |
| Kouanda, S | 1 |
| Tiono, AB | 1 |
| Sirima, SB | 1 |
| Hughes, E | 1 |
| Wallender, E | 1 |
| Mohamed Ali, A | 1 |
| Jagannathan, P | 1 |
| Savic, RM | 1 |
| Osarfo, J | 1 |
| Tagbor, H | 4 |
| Cairns, M | 1 |
| Alifrangis, M | 1 |
| Magnussen, P | 1 |
| Clark, RL | 1 |
| Bassi, PU | 1 |
| Osakwe, AI | 1 |
| Isah, A | 1 |
| Suku, C | 1 |
| Kalat, M | 1 |
| Jalo, I | 1 |
| Wammanda, RD | 1 |
| Ugochukwu, C | 1 |
| Adesina, O | 1 |
| Nyong, EE | 1 |
| Osungwu, F | 1 |
| Pal, S | 1 |
| Nwoasu, SC | 1 |
| Wallberg, M | 1 |
| Coulter, D | 1 |
| Pukrittayakamee, S | 1 |
| Hien, TT | 1 |
| Faiz, MA | 1 |
| Mokuolu, OA | 1 |
| Dondorp, AM | 1 |
| Mulenga, M | 2 |
| Halidou, T | 1 |
| Phiri, LK | 1 |
| Kalanda, G | 2 |
| Traore, M | 1 |
| Mwakazanga, D | 1 |
| Claeys, Y | 2 |
| Schurmans, C | 2 |
| De Crop, M | 2 |
| Menten, J | 2 |
| Ravinetto, R | 2 |
| Thriemer, K | 2 |
| Van Geertruyden, JP | 2 |
| Mutabingwa, T | 2 |
| Ukah, M | 1 |
| Badejoko, O | 1 |
| Ogunniyi, S | 1 |
| Loto, O | 1 |
| Aboderin, O | 1 |
| Fatusi, A | 1 |
| Pekyi, D | 1 |
| Ampromfi, AA | 1 |
| Traoré-Coulibaly, M | 1 |
| Tahita, MC | 1 |
| Madanitsa, M | 1 |
| Gbekor, P | 1 |
| Antwi, G | 1 |
| Van Overmeir, C | 1 |
| Hachizovu, S | 1 |
| Kabuya, JB | 1 |
| Mulenga, J | 1 |
| Clerk, CA | 1 |
| Bruce, J | 2 |
| Affipunguh, PK | 1 |
| Mensah, N | 1 |
| Hodgson, A | 1 |
| Greenwood, B | 3 |
| Mutabingwa, TK | 2 |
| Muze, K | 1 |
| Ord, R | 1 |
| Briceño, M | 1 |
| Greenwood, BM | 1 |
| Drakeley, C | 1 |
| Whitty, CJ | 1 |
| Ndiaye, JL | 1 |
| Randrianarivelojosia, M | 1 |
| Sagara, I | 1 |
| Brasseur, P | 1 |
| Ndiaye, I | 1 |
| Faye, B | 1 |
| Randrianasolo, L | 1 |
| Ratsimbasoa, A | 1 |
| Forlemu, D | 1 |
| Moor, VA | 1 |
| Traore, A | 1 |
| Dicko, Y | 1 |
| Dara, N | 1 |
| Lameyre, V | 1 |
| Diallo, M | 1 |
| Djimde, A | 1 |
| Same-Ekobo, A | 1 |
| Gaye, O | 1 |
| Sayang, C | 1 |
| Gausseres, M | 1 |
| Vernazza-Licht, N | 1 |
| Malvy, D | 1 |
| Bley, D | 1 |
| Millet, P | 1 |
| Willcox, ML | 1 |
| Graz, B | 1 |
| Diakite, C | 1 |
| Falquet, J | 1 |
| Dackouo, F | 1 |
| Sidibe, O | 1 |
| Giani, S | 1 |
| Diallo, D | 1 |
| Beeson, JG | 1 |
| Rogerson, SJ | 1 |
| Mueller, I | 1 |
| Richards, JS | 1 |
| Fowkes, FJ | 1 |
| Jullien, V | 2 |
| Lindegardh, N | 2 |
| Win, AK | 1 |
| Hsi, P | 1 |
| Cammas, M | 2 |
| Singhasivanon, P | 2 |
| Bergstrand, M | 1 |
| Day, NP | 1 |
| Thomas, F | 1 |
| Erhart, A | 1 |
| Bhattarai, A | 1 |
| Maini-Thapar, M | 1 |
| Ali, AS | 1 |
| Björkman, A | 1 |
| Rolland, E | 1 |
| Checchi, F | 1 |
| Pinoges, L | 1 |
| Balkan, S | 1 |
| Guthmann, JP | 1 |
| ter Kuile, FO | 1 |
| Browne, E | 1 |
| Randal, A | 1 |
| Nyunt, MM | 1 |
| Plowe, CV | 1 |
| Stürchler, D | 1 |
| Phillips, RE | 1 |
| Sharp, PT | 1 |
| Harvey, P | 1 |
| Cambournac, FJ | 1 |
| Malle, LN | 1 |
| de Geus, A | 1 |
| Wernsdorfer, WH | 1 |
| Ndumbe, PM | 1 |
| McDermott, JM | 1 |
| Heymann, DL | 1 |
| Wirima, JJ | 1 |
| Macheso, AP | 1 |
| Wahl, RD | 1 |
| Steketee, RW | 1 |
| Campbell, CC | 1 |
| Rolfe, M | 1 |
| Saint-Yves, IF | 1 |
| Laing, AB | 1 |
| Hennig, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Feasibility, Acceptability and Costs of a Strategy Deploying Multiple First-lines Artemisinin-based Combination Therapies for Uncomplicated Malaria: a Pilot Programme in the Health District of Kaya, Burkina Faso[NCT04265573] | 150,000 participants (Actual) | Observational | 2018-11-10 | Completed | |||
| Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity[NCT05757167] | Phase 4 | 2,500 participants (Anticipated) | Interventional | 2023-11-06 | Recruiting | ||
| Incorporation of the 'Ottawa Malaria Decision Aid' Into the Pre-travel Consultation Process: Assessment of Travelers' Knowledge, Decisional Conflict, Preparation for Decision-making and Medication Adherence Compared to Standard Care[NCT01976325] | 100 participants (Anticipated) | Interventional | 2014-01-31 | Recruiting | |||
| Infections in Migrants in Sweden - the Importance of Malaria and Other Parasitic Infections[NCT05086887] | 715 participants (Anticipated) | Observational [Patient Registry] | 2019-04-15 | Recruiting | |||
| Clinical Efficacy of Artemisinin-based Combination Therapy for Treatment of Uncomplicated Plasmodium Falciparum Malaria in North Sumatera, Indonesia and the Association of Molecular Markers With Treatment Outcomes[NCT02325180] | Phase 4 | 338 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| Safe and Efficacious Artemisinin-based Combination Treatments for African Pregnant Women With Malaria[NCT00852423] | Phase 3 | 3,428 participants (Actual) | Interventional | 2010-06-30 | Completed | ||
| Efficacy of Sulphadoxine-pyrimethamine and Amodiaquine Alone or in Combination as Intermittent Preventive Treatment in Pregnancy in the Kassena-Nankana District of Ghana: a Randomized Controlled Trial[NCT00146783] | Phase 2/Phase 3 | 3,642 participants (Actual) | Interventional | 2004-06-30 | Completed | ||
| Treating Malaria During Pregnancy: A Randomized Trial of Potential Options for Treatment in an Area of High Drug Resistance in Tanzania[NCT00146731] | Phase 3 | 310 participants (Actual) | Interventional | 2004-01-31 | Completed | ||
| Multinational, Randomized, Comparative Study of the Efficacy and Safety of Three Therapeutic Regimens: Coarsucam™ (Artesunate + Amodiaquine Fixed-Dose Combination) Administered in 1 or 2 Intakes Per Day Versus Coartem® (Artemether + Lumefantrine) in the T[NCT00316329] | Phase 3 | 1,032 participants | Interventional | 2006-03-31 | Completed | ||
| A Randomised Double Blind Clinical Trial of Amodiaquine (AQ) and Sulphadoxine-pyrimethamine (SP) Used Singly and in Combination (AQ+SP) Compared With Chloroquine (CQ) in the Treatment of Falciparum Malaria Infection in Pregnancy[NCT00131703] | Phase 3 | 900 participants | Interventional | 2003-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for amodiaquine and Pregnancy
| Article | Year |
|---|---|
Pharmacokinetic considerations in seasonal malaria chemoprevention.
Topics: Amodiaquine; Antimalarials; Chemoprevention; Child; Child, Preschool; Drug Combinations; Drug Therap | 2022 |
Efficacy and tolerability of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: a systematic review and individual patient data meta-analysis.
Topics: Amodiaquine; Anti-Bacterial Agents; Antimalarials; Artemisinins; Artesunate; Atovaquone; Clindamycin | 2020 |
Malaria PK/PD and the Role Pharmacometrics Can Play in the Global Health Arena: Malaria Treatment Regimens for Vulnerable Populations.
Topics: Amodiaquine; Anti-HIV Agents; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins | 2021 |
Animal Embryotoxicity Studies of Key Non-Artemisinin Antimalarials and Use in Women in the First Trimester.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Malaria; Malar | 2017 |
Malaria.
Topics: Africa South of the Sahara; Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate | 2014 |
Malaria.
Topics: Africa South of the Sahara; Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate | 2014 |
Malaria.
Topics: Africa South of the Sahara; Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate | 2014 |
Malaria.
Topics: Africa South of the Sahara; Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate | 2014 |
Malaria.
Topics: Africa South of the Sahara; Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate | 2014 |
Malaria.
Topics: Africa South of the Sahara; Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate | 2014 |
Malaria.
Topics: Africa South of the Sahara; Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate | 2014 |
Malaria.
Topics: Africa South of the Sahara; Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate | 2014 |
Malaria.
Topics: Africa South of the Sahara; Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate | 2014 |
Can amodiaquine be used safely during pregnancy?
Topics: Africa; Amodiaquine; Antimalarials; Contraindications; Female; Humans; Malaria; Pregnancy; Pregnancy | 2004 |
The safety of amodiaquine use in pregnant women.
Topics: Amodiaquine; Animals; Antimalarials; Female; Humans; Malaria, Falciparum; Pregnancy; Pregnancy Compl | 2007 |
Malaria prophylaxis in travellers: the current position.
Topics: Africa; Amodiaquine; Antimalarials; Asia; Chloroquine; Culicidae; Drug Resistance; Female; Humans; I | 1984 |
[Current information on treatment and prophylaxis of malaria (author's transl)].
Topics: Adolescent; Adult; Amodiaquine; Child; Child, Preschool; Chloroquine; Dose-Response Relationship, Dr | 1979 |
15 trials available for amodiaquine and Pregnancy
| Article | Year |
|---|---|
Efficacy of artesunate-amodiaquine and artemether-lumefantrine for uncomplicated Plasmodium falciparum malaria in Madagascar, 2018.
Topics: Adolescent; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Chi | 2021 |
Dihydroartemisinin-piperaquine versus artesunate-amodiaquine for treatment of malaria infection in pregnancy in Ghana: an open-label, randomised, non-inferiority trial.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Female; Humans; Pregnancy; | 2017 |
Safe and efficacious artemisinin-based combination treatments for African pregnant women with malaria: a multicentre randomized control trial.
Topics: Adult; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesuna | 2015 |
A randomized trial of artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in pregnancy.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisini | 2015 |
Four Artemisinin-Based Treatments in African Pregnant Women with Malaria.
Topics: Adult; Africa; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; | 2016 |
Four Artemisinin-Based Treatments in African Pregnant Women with Malaria.
Topics: Adult; Africa; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; | 2016 |
Four Artemisinin-Based Treatments in African Pregnant Women with Malaria.
Topics: Adult; Africa; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; | 2016 |
Four Artemisinin-Based Treatments in African Pregnant Women with Malaria.
Topics: Adult; Africa; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; | 2016 |
A randomized, controlled trial of intermittent preventive treatment with sulfadoxine-pyrimethamine, amodiaquine, or the combination in pregnant women in Ghana.
Topics: Amodiaquine; Anemia; Animals; Antimalarials; Child, Preschool; Drug Combinations; Drug Therapy, Comb | 2008 |
Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania.
Topics: Adult; Amodiaquine; Artemisinins; Artesunate; Dapsone; Drug Combinations; Drug Therapy, Combination; | 2009 |
Randomized, multicentre assessment of the efficacy and safety of ASAQ--a fixed-dose artesunate-amodiaquine combination therapy in the treatment of uncomplicated Plasmodium falciparum malaria.
Topics: Adolescent; Adult; Africa; Aged; Aged, 80 and over; Amodiaquine; Animals; Antimalarials; Artemisinin | 2009 |
Is parasite clearance clinically important after malaria treatment in a high transmission area? A 3-month follow-up of home-based management with herbal medicine or ACT.
Topics: Adolescent; Amodiaquine; Antimalarials; Argemone; Artemisinins; Child; Child, Preschool; Drug Combin | 2011 |
Pharmacokinetics of amodiaquine and desethylamodiaquine in pregnant and postpartum women with Plasmodium vivax malaria.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Female; Humans; Malaria, Vivax; Postpartum Period; Pr | 2011 |
Efficacy, safety, and tolerability of amodiaquine plus sulphadoxine-pyrimethamine used alone or in combination for malaria treatment in pregnancy: a randomised trial.
Topics: Adult; Amodiaquine; Antimalarials; Chloroquine; Drug Administration Schedule; Drug Combinations; Fem | 2006 |
Malaria in infants whose mothers received chemoprophylaxis: response to amodiaquine therapy.
Topics: Administration, Oral; Amodiaquine; Chloroquine; Drug Resistance; Female; Humans; Immunity, Maternall | 1992 |
Falciparum malaria and pregnancy: relationship and treatment response.
Topics: Adolescent; Adult; Amodiaquine; Animals; Female; Humans; Malaria; Plasmodium falciparum; Pregnancy; | 1988 |
Efficacy of chemoprophylaxis in preventing Plasmodium falciparum parasitaemia and placental infection in pregnant women in Malawi.
Topics: Amodiaquine; Animals; Chloroquine; Female; Humans; Malaria; Malawi; Placenta Diseases; Plasmodium fa | 1988 |
The suppression of malaria with dapolar: a trial of 4-monthly doses in a village community in the Gambia, West Africa.
Topics: Acetanilides; Adolescent; Adult; Age Factors; Amodiaquine; Antimalarials; Child; Child, Preschool; F | 1971 |
19 other studies available for amodiaquine and Pregnancy
| Article | Year |
|---|---|
Artesunate-amodiaquine and artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in Liberia: in vivo efficacy and frequency of molecular markers.
Topics: Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artesunate; Child | 2022 |
Therapeutic efficacy of artesunate-amodiaquine and artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in Chad: clinical and genetic surveillance.
Topics: Adult; Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisini | 2023 |
Optimal Approach and Strategies to Strengthen Pharmacovigilance in Sub-Saharan Africa: A Cohort Study of Patients Treated with First-Line Artemisinin-Based Combination Therapies in the Nanoro Health and Demographic Surveillance System, Burkina Faso.
Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Burkina Faso; Child; Child, Preschool; Cohort | 2020 |
Protocol for a quasi-experimental study to assess the feasibility, acceptability and costs of multiple first-lines artemisinin-based combination therapies for uncomplicated malaria in the Kaya health district, Burkina Faso.
Topics: Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Bur | 2021 |
Safety of Artemisinin-Based Combination Therapies in Nigeria: A Cohort Event Monitoring Study.
Topics: Adolescent; Adult; Amodiaquine; Anti-Infective Agents; Antimalarials; Artemisinins; Child; Child, Pr | 2013 |
Treatment of malaria from monotherapy to artemisinin-based combination therapy by health professionals in urban health facilities in Yaoundé, central province, Cameroon.
Topics: Adult; Aged; Aged, 80 and over; Amodiaquine; Antimalarials; Artemisinins; Cameroon; Child, Preschool | 2009 |
Intermittent preventive treatment to reduce the burden of malaria in children: new evidence on integration and delivery.
Topics: Amodiaquine; Antimalarials; Child, Preschool; Drug Combinations; Female; Humans; Infant; Infant, New | 2011 |
Population pharmacokinetic and pharmacodynamic modeling of amodiaquine and desethylamodiaquine in women with Plasmodium vivax malaria during and after pregnancy.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Biotransformation; Body Weight; Drug Administration S | 2012 |
Amodiaquine during pregnancy.
Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Drug Therapy, Combination; Female; Humans; Malaria; | 2004 |
Operational response to malaria epidemics: are rapid diagnostic tests cost-effective?
Topics: Adolescent; Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Cost-Benefit An | 2006 |
Amodiaquine, malaria, pregnancy: the old new drug.
Topics: Amodiaquine; Antimalarials; Drug Combinations; Drug Therapy, Combination; Female; Ghana; Humans; Mal | 2006 |
Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Dapsone; Drug Design; | 2007 |
Management of Plasmodium falciparum malaria.
Topics: Amodiaquine; Anemia; Antimalarials; Brain Diseases; Chloroquine; Drug Resistance; Female; Humans; Hy | 1984 |
Malaria and growth stunting in young children of the highlands of Papua New Guinea.
Topics: Amodiaquine; Anthropometry; Child; Child, Preschool; Chloroquine; Female; Growth Disorders; Health S | 1980 |
Curative and preventive treatment of uncomplicated malaria in public health institutions in Cameroon.
Topics: Amodiaquine; Antimalarials; Cameroon; Child; Chloroquine; Drug Combinations; Female; Humans; Malaria | 1989 |
Multiple drug resistant Plasmodium falciparum malaria in a pregnant indigenous Zambian woman.
Topics: Adult; Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Erythro | 1988 |
Malaria prophylaxis for Canadian travellers.
Topics: Amodiaquine; Canada; Chloroquine; Dapsone; Doxycycline; Drug Combinations; Drug Resistance, Microbia | 1985 |
The chemotherapy and prophylaxis of malaria.
Topics: Adolescent; Adult; Amodiaquine; Child; Child, Preschool; Chloroquine; Drug Resistance, Microbial; Fe | 1973 |
[Ileus in the puerperium. (Case report)].
Topics: Adult; Amodiaquine; Female; Gastrointestinal Motility; Humans; Intestinal Obstruction; Laparotomy; M | 1968 |