Page last updated: 2024-10-22

amodiaquine and Parasitemia

amodiaquine has been researched along with Parasitemia in 75 studies

Amodiaquine: A 4-aminoquinoline compound with anti-inflammatory properties.
amodiaquine : A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position.

Parasitemia: The presence of parasites (especially malarial parasites) in the blood. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"To compare the artesunate-amodiaquine and artemether-lumefantrine combinations in the treatment of acute uncomplicated falciparum malaria during pregnancy."9.20A randomized trial of artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in pregnancy. ( Aboderin, O; Badejoko, O; Fatusi, A; Loto, O; Ogunniyi, S; Ukah, M, 2015)
" The objective was to assess the efficacy and safety of repeated administrations of two fixed-dose presentations of ACT--artesunate plus amodiaquine (ASAQ) and artemether-lumefantrine (AL)--in subsequent episodes of Plasmodium falciparum malaria."9.15Repeated treatment of recurrent uncomplicated Plasmodium falciparum malaria in Senegal with fixed-dose artesunate plus amodiaquine versus fixed-dose artemether plus lumefantrine: a randomized, open-label trial. ( Barry, A; Cissé, B; Faye, B; Gaye, O; Gueye, A; Lameyre, V; Ndiaye, D; Ndiaye, I; Ndiaye, JL; Tchania, C; Tine, R, 2011)
"The treatment efficacy and effects of artemether-lumefantrine (AL) and amodiaquine-sulfalene-pyrimethamine (ASP) on gametocyte carriage were evaluated in 181 children < or = 10 years of age with uncomplicated Plasmodium falciparum malaria randomized to receive either drug combination."9.12Therapeutic efficacy and effects of artemether-lumefantrine and amodiaquine-sulfalene-pyrimethamine on gametocyte carriage in children with uncomplicated Plasmodium falciparum malaria in southwestern Nigeria. ( Adedeji, AA; Fateye, BA; Fehintola, FA; Folarin, OA; Gbotosho, GO; Happi, CT; Sowunmi, A; Tambo, E, 2007)
"The Angolan government recommends three artemisinin-based combinations for the treatment of uncomplicated Plasmodium falciparum malaria: artemether-lumefantrine (AL), artesunate-amodiaquine (ASAQ), and dihydroartemisinin-piperaquine (DP)."7.88Efficacy and safety of artemether-lumefantrine, artesunate-amodiaquine, and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in three provinces in Angola, 2017. ( Andrade, BN; Davlantes, E; Dimbu, PR; Dos Santos Souza, S; Félix, J; Ferreira, CM; Florinda Joao, M; Fortes, F; Halsey, ES; Martins, JF; Mbounga, E; Owens, C; Plucinski, MM; Pode, D; Sanhangala, E; Talundzic, E; Udhayakumar, V; Wiesner, L, 2018)
"falciparum malaria was compared with that of CQ, each drug being given at 10 mg/kg per day for 3 days (days 0, 1 and 2)."6.70Randomized comparison of chloroquine and amodiaquine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children. ( Adedeji, AA; Ayede, AI; Falade, AG; Falade, CO; Happi, TC; Ndikum, VN; Oduola, AM; Sowunmi, A; Sowunmi, CO, 2001)
" Adverse events were documented in less than 2% of participants for both drugs."5.62In vivo efficacy and safety of artemether-lumefantrine and amodiaquine-artesunate for uncomplicated Plasmodium falciparum malaria in Mozambique, 2018. ( Aide, P; Bassat, Q; Candrinho, B; Carvalho, E; Chidimatembue, A; Enosse, S; Halsey, ES; Lucchi, N; Macete, E; Mayor, A; Moriarty, LF; Nhacolo, A; Nhama, A; Nhamússua, L; Saifodine, A; Salvador, C; Svigel, SS; Zulliger, R, 2021)
"To compare the artesunate-amodiaquine and artemether-lumefantrine combinations in the treatment of acute uncomplicated falciparum malaria during pregnancy."5.20A randomized trial of artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in pregnancy. ( Aboderin, O; Badejoko, O; Fatusi, A; Loto, O; Ogunniyi, S; Ukah, M, 2015)
" The objective was to assess the efficacy and safety of repeated administrations of two fixed-dose presentations of ACT--artesunate plus amodiaquine (ASAQ) and artemether-lumefantrine (AL)--in subsequent episodes of Plasmodium falciparum malaria."5.15Repeated treatment of recurrent uncomplicated Plasmodium falciparum malaria in Senegal with fixed-dose artesunate plus amodiaquine versus fixed-dose artemether plus lumefantrine: a randomized, open-label trial. ( Barry, A; Cissé, B; Faye, B; Gaye, O; Gueye, A; Lameyre, V; Ndiaye, D; Ndiaye, I; Ndiaye, JL; Tchania, C; Tine, R, 2011)
"Artesunate (AS) plus amodiaquine (AQ) is one artemisinin-based combination (ACT) recommended by the WHO for treating Plasmodium falciparum malaria."5.14The efficacy and safety of a new fixed-dose combination of amodiaquine and artesunate in young African children with acute uncomplicated Plasmodium falciparum. ( Diarra, A; Gansané, A; Kiechel, JR; Konaté, AT; Morgan, CC; Olliaro, PL; Ouédraogo, A; Sirima, SB; Taylor, WR; Tiono, AB, 2009)
"The use of sulfadoxine-pyrimethamine (SP) for intermittent preventive treatment in pregnancy (IPTp) is threatened by the spread of resistance to SP."5.13A randomized, controlled trial of intermittent preventive treatment with sulfadoxine-pyrimethamine, amodiaquine, or the combination in pregnant women in Ghana. ( Affipunguh, PK; Bruce, J; Chandramohan, D; Clerk, CA; Greenwood, B; Hodgson, A; Mensah, N, 2008)
"The treatment efficacy and effects of artemether-lumefantrine (AL) and amodiaquine-sulfalene-pyrimethamine (ASP) on gametocyte carriage were evaluated in 181 children < or = 10 years of age with uncomplicated Plasmodium falciparum malaria randomized to receive either drug combination."5.12Therapeutic efficacy and effects of artemether-lumefantrine and amodiaquine-sulfalene-pyrimethamine on gametocyte carriage in children with uncomplicated Plasmodium falciparum malaria in southwestern Nigeria. ( Adedeji, AA; Fateye, BA; Fehintola, FA; Folarin, OA; Gbotosho, GO; Happi, CT; Sowunmi, A; Tambo, E, 2007)
" In order to investigate the latter, we conducted a randomized clinical trial testing the AR plus amodiaquine (AQ) combination for the treatment of uncomplicated Plasmodium falciparum malaria in Burkina Faso."5.11A randomized trial of amodiaquine and artesunate alone and in combination for the treatment of uncomplicated falciparum malaria in children from Burkina Faso. ( Barennes, H; Koussoubé-Balima, T; Nagot, N; Ouedraogo, A; Sanou, T; Valea, I; Yé, S, 2004)
"The study examined the efficacy of chloroquine (CQ), amodiaquine (AQ) and sulphadoxine-pyrimethamine (SP) for the treatment of uncomplicated Plasmodium falciparum malaria in Ghana."5.11A randomized comparative study of chloroquine, amodiaquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated malaria in Ghana. ( Amankwa, J; Ansah, NA; Ansah, P; Anto, F; Anyorigiya, T; Atuguba, F; Hodgson, A; Mumuni, G; Oduro, AR, 2005)
" The authors recommend that the treatment to be used in Abie must be firstly amodiaquine followed by sulfadoxine-pyrimethamine in cases where there is persistent asymptomatic parasitemia."5.11[Evaluation of the therapeutic efficacy of amodiaquine versus chloroquine in the treatment of uncomplicated malaria in Abie, Côte-d'Ivoire]. ( Adjetey, TA; Affoumou, GB; Barro-Kiki, P; Kone, M; Loukou, DD; Menan, EI; Nebavi, NG; Yavo, W, 2005)
"We evaluated gametocyte carriage and intensities of gametocytaemia in 710 children presenting with acute, symptomatic, uncomplicated Plasmodium falciparum malaria who were treated with various antimalarial drug regimens: chloroquine (CQ); chloroquine plus chlorpheniramine, a histamine H1 receptor antagonist that reverses CQ resistance in P."5.10Plasmodium falciparum gametocytaemia in Nigerian children: before, during and after treatment with antimalarial drugs. ( Fateye, BA; Sowunmi, A, 2003)
"We conducted two randomized clinical trials to determine the in vivo efficacy of amodiaquine and sulfadoxine/pyrimethamine in treating Plasmodium falciparum malaria."5.09In vivo efficacy study of amodiaquine and sulfadoxine/ pyrimethamine in Kibwezi, Kenya and Kigoma, Tanzania. ( Ashruf, G; Bennebroek, J; Gikunda, S; Gorissen, E; Kager, PA; Lamboo, M; Mbaruku, G, 2000)
"In a prospective longitudinal in vivo study, neutrophil rates were compared with malaria carriage after treatment with different ACTs: Artemether - lumefantrine (AL), Artesunate - amodiaquine (ASAQ), Dihydroartemisinin - piperaquine (DP) or Pyronaridine artesunate (PA)."4.31Variation in neutrophil levels and artemisinin-based combination therapy efficacy in West-Africa. ( Arama, C; Beavogui, AH; Dicko, A; Djimde, A; Djimde, M; Fofana, B; Kayentao, K; Mens, PF; Ouedraogo, JB; Sagara, I; Schallig, HD; Sirima, SB; Tshiongo, JK, 2023)
" Whether the addition of azithromycin to the monthly sulfadoxine-pyrimethamine plus amodiaquine used for seasonal malaria chemoprevention could reduce mortality and morbidity among African children was unclear."3.91Effect of Adding Azithromycin to Seasonal Malaria Chemoprevention. ( Barry, A; Cairns, M; Chandramohan, D; Coumare, S; Diarra, M; Dicko, A; Doumbo, O; Greenwood, B; Kuepfer, I; Milligan, P; Nikiema, F; Ouedraogo, JB; Sagara, I; Tapily, A; Thera, I; Tinto, H; Traore, A; Yerbanga, S; Zongo, I, 2019)
"The Angolan government recommends three artemisinin-based combinations for the treatment of uncomplicated Plasmodium falciparum malaria: artemether-lumefantrine (AL), artesunate-amodiaquine (ASAQ), and dihydroartemisinin-piperaquine (DP)."3.88Efficacy and safety of artemether-lumefantrine, artesunate-amodiaquine, and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in three provinces in Angola, 2017. ( Andrade, BN; Davlantes, E; Dimbu, PR; Dos Santos Souza, S; Félix, J; Ferreira, CM; Florinda Joao, M; Fortes, F; Halsey, ES; Martins, JF; Mbounga, E; Owens, C; Plucinski, MM; Pode, D; Sanhangala, E; Talundzic, E; Udhayakumar, V; Wiesner, L, 2018)
" This study reports the results of therapeutic efficacy studies conducted on artemether-lumefantrine and artesunate-amodiaquine for the treatment of uncomplicated Plasmodium falciparum malaria in Togo, between 2005 and 2009."3.78Surveillance of the efficacy of artemether-lumefantrine and artesunate-amodiaquine for the treatment of uncomplicated Plasmodium falciparum among children under five in Togo, 2005-2009. ( Agbo, YM; Barrette, A; Bogreau, H; Dorkenoo, MA; Kutoati, S; Morgah, K; Sodahlon, YK, 2012)
" Adverse events and clinical and parasitological outcomes were recorded."2.73A randomised trial to assess the safety and efficacy of artemether-lumefantrine (Coartem) for the treatment of uncomplicated Plasmodium falciparum malaria in Rwanda. ( D'Alessandro, U; Fanello, CI; Karema, C; Ngamije, D; van Doren, W; Van Overmeir, C, 2007)
"Nearly all recurrences were due to new infections."2.73Artemether-lumefantrine versus amodiaquine plus sulfadoxine-pyrimethamine for uncomplicated falciparum malaria in Burkina Faso: a randomised non-inferiority trial. ( Dokomajilar, C; Dorsey, G; Guiguemde, RT; Ouedraogo, JB; Rosenthal, PJ; Rouamba, N; Tinto, H; Zongo, I, 2007)
"The main adverse events were gastrointestinal disorders (2."2.73Randomized, comparative study of the efficacy and safety of artesunate plus amodiaquine, administered as a single daily intake versus two daily intakes in the treatment of uncomplicated falciparum malaria. ( Brasseur, P; Cisse, M; Diouf, AM; Faye, B; Gaye, O; Kuété, T; Lameyre, V; Ndiaye, JL; Same-Ekobo, A; Seck, PA, 2008)
"Amodiaquine is a common partner drug in different malaria combination therapies used or investigated in sub-Saharan Africa, but data on its efficacy as a single drug are scarce."2.73Efficacy of amodiaquine in the treatment of uncomplicated falciparum malaria in young children of rural north-western Burkina Faso. ( Coulibaly, B; Mandi, G; Meissner, P; Mockenhaupt, FP; Müller, O, 2008)
"falciparum malaria was compared with that of CQ, each drug being given at 10 mg/kg per day for 3 days (days 0, 1 and 2)."2.70Randomized comparison of chloroquine and amodiaquine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children. ( Adedeji, AA; Ayede, AI; Falade, AG; Falade, CO; Happi, TC; Ndikum, VN; Oduola, AM; Sowunmi, A; Sowunmi, CO, 2001)
" Adverse events were documented in less than 2% of participants for both drugs."1.62In vivo efficacy and safety of artemether-lumefantrine and amodiaquine-artesunate for uncomplicated Plasmodium falciparum malaria in Mozambique, 2018. ( Aide, P; Bassat, Q; Candrinho, B; Carvalho, E; Chidimatembue, A; Enosse, S; Halsey, ES; Lucchi, N; Macete, E; Mayor, A; Moriarty, LF; Nhacolo, A; Nhama, A; Nhamússua, L; Saifodine, A; Salvador, C; Svigel, SS; Zulliger, R, 2021)
"Artemisinin resistance, a long parasite clearance half-life in response to artemisinin, has been described in patients with Plasmodium falciparum malaria in southeast Asia."1.39Plasmodium falciparum clearance rates in response to artesunate in Malian children with malaria: effect of acquired immunity. ( Anderson, JM; Chiang, S; Diakite, M; Diakite, SA; Doumbia, S; Doumbouya, M; Fairhurst, RM; Fay, MP; Keita, AS; Konate, DS; Long, CA; Lopera-Mesa, TM; Ndiaye, D; Sa, JM; Stepniewska, K; Traore, K; Zeituni, AE, 2013)
" Intermittent preventive treatment for children (IPTc) combined with timely treatment of malaria related febrile illness at home to reduce parasite prevalence and malaria morbidity in children aged between six and 60 months in a coastal community in Ghana."1.37Two-year evaluation of Intermittent Preventive Treatment for Children (IPTc) combined with timely home treatment for malaria control in Ghana. ( Ahorlu, CK; Koram, KA; Seake-Kwawu, A; Weiss, MG, 2011)
"Recrudescence was detected by a thick blood smear and confirmed by polymerase chain reaction."1.35Some features of primary and recrudescent amodiaquine-resistant Plasmodium falciparum infections in Nigerian children. ( Balogun, ST; Gbotosho, GO; Happi, CT; Sowunmi, A, 2008)
"Falciparum Malaria is hyperendemic in southern Nigeria and chloroquine resistance is an increasing problem."1.33Efficacy of amodiaquine in uncomplicated falciparum malaria in Nigeria in an area with high-level resistance to chloroquine and sulphadoxine/pyrimethamine. ( Göbels, K; Graupner, J; Grobusch, MP; Häussinger, D; Lund, A; Richter, J, 2005)
"Amodiaquine was 3."1.31In vitro sensitivity of Plasmodium falciparum to amodiaquine compared with other major antimalarials in Madagascar. ( Ariey, F; Duchemin, JB; Harisoa, JL; Mauclere, P; Pietra, V; Rabarijaona, LP; Raharimalala, LA; Rakotomanana, F; Ranaivo, L; Randrianarivelojosia, M; Robert, V, 2002)
"Amodiaquine was shown to be more effective than chloroquine in clinical response and ridding patients of parasites: adequate clinical response was significantly higher with amodiaquine than chloroquine [100% (27/27) versus 45% (9/20), p < 0."1.31[Evaluation of efficacy and tolerance of amodiaquine versus chloroquine in the treatment of uncomplicated malaria outbreak in children of Gabon]. ( Bouyou Akotet, M; Guiyedi, V; Koko, J; Kombila, M; Mabika Manfoumbi, M; Matsiégui, PB; Traoré, B, 2001)

Research

Studies (75)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (4.00)18.2507
2000's37 (49.33)29.6817
2010's31 (41.33)24.3611
2020's4 (5.33)2.80

Authors

AuthorsStudies
Cross, RM1
Flanigan, DL1
Monastyrskyi, A1
LaCrue, AN1
Sáenz, FE1
Maignan, JR1
Mutka, TS1
White, KL1
Shackleford, DM1
Bathurst, I1
Fronczek, FR1
Wojtas, L1
Guida, WC1
Charman, SA1
Burrows, JN1
Kyle, DE1
Manetsch, R1
Nhama, A1
Nhamússua, L1
Macete, E1
Bassat, Q1
Salvador, C1
Enosse, S1
Candrinho, B1
Carvalho, E1
Nhacolo, A1
Chidimatembue, A1
Saifodine, A1
Zulliger, R1
Lucchi, N1
Svigel, SS1
Moriarty, LF1
Halsey, ES2
Mayor, A1
Aide, P1
Pembet Singana, B1
Casimiro, PN1
Matondo Diassivi, B1
Kobawila, SC1
Youndouka, JM1
Basco, LK3
Ringwald, P1
Briolant, S1
Ndounga, M2
Djimde, M1
Kayentao, K1
Tshiongo, JK1
Fofana, B1
Arama, C1
Sirima, SB3
Ouedraogo, JB4
Beavogui, AH1
Sagara, I2
Dicko, A3
Mens, PF1
Schallig, HD1
Djimde, A2
Akano, K5
Fatunmbi, B4
Ntadom, G6
Ayede, AI4
Aderoyeje, T4
Bakre, A1
Alebiosu, OT1
Akpoborie, O1
Okafor, C1
Gbotosho, GO9
Folarin, OA5
Ebenebe, JC2
Ambe, J2
Wammanda, R2
Jiya, N2
Finomo, F2
Emechebe, G2
Mokuolu, O2
Agomo, C4
Oguche, S4
Happi, C3
Sowunmi, A17
Esu, EB1
Oringanje, C1
Meremikwu, MM1
Ayede, A1
Okafor, H1
Watila, I2
Meremikwu, M2
Ogala, W2
Agomo, P2
Adowoye, E1
Gbotosho, G1
Folarin, O1
Valverde, EA1
Romero, AH1
Acosta, ME1
Gamboa, N1
Henriques, G1
Rodrigues, JR1
Ciangherotti, C1
López, SE1
Davlantes, E1
Dimbu, PR1
Ferreira, CM1
Florinda Joao, M1
Pode, D1
Félix, J1
Sanhangala, E1
Andrade, BN1
Dos Santos Souza, S1
Talundzic, E1
Udhayakumar, V1
Owens, C1
Mbounga, E1
Wiesner, L1
Martins, JF1
Fortes, F1
Plucinski, MM1
Useh, F1
Oyibo, W1
Abdulkadir, M1
Ezeigwe, NM1
Munyangi, J1
Cornet-Vernet, L1
Idumbo, M1
Lu, C1
Lutgen, P1
Perronne, C1
Ngombe, N1
Bianga, J1
Mupenda, B1
Lalukala, P1
Mergeai, G1
Mumba, D1
Towler, M1
Weathers, P1
Chandramohan, D3
Zongo, I2
Cairns, M1
Kuepfer, I1
Diarra, M1
Barry, A3
Tapily, A1
Nikiema, F1
Yerbanga, S1
Coumare, S1
Thera, I1
Traore, A1
Milligan, P1
Tinto, H3
Doumbo, O1
Greenwood, B3
Lopera-Mesa, TM1
Doumbia, S1
Chiang, S1
Zeituni, AE1
Konate, DS1
Doumbouya, M1
Keita, AS1
Stepniewska, K1
Traore, K1
Diakite, SA1
Ndiaye, D2
Sa, JM1
Anderson, JM1
Fay, MP1
Long, CA1
Diakite, M1
Fairhurst, RM1
Ojurongbe, O1
Lawal, OA1
Abiodun, OO1
Okeniyi, JA1
Oyeniyi, AJ1
Oyelami, OA1
Zwang, J1
Dorsey, G3
Mårtensson, A1
d'Alessandro, U2
Ndiaye, JL4
Karema, C2
Brasseur, P2
Olliaro, P2
Onyamboko, MA1
Fanello, CI2
Wongsaen, K1
Tarning, J1
Cheah, PY1
Tshefu, KA1
Dondorp, AM1
Nosten, F1
White, NJ1
Day, NP1
Okafor, HU1
Banjo, O1
Okuboyejo, T2
Ogunrinde, G1
Odey, F1
Aina, O1
Sofola, T1
Ukah, M1
Badejoko, O1
Ogunniyi, S1
Loto, O1
Aboderin, O1
Fatusi, A1
Sondo, P1
Derra, K1
Diallo Nakanabo, S1
Tarnagda, Z1
Kazienga, A1
Zampa, O1
Valéa, I2
Sorgho, H1
Owusu-Dabo, E1
Guiguemdé, TR1
Adewoye, EO2
Siqueira, AM1
Alencar, AC1
Melo, GC1
Magalhaes, BL1
Machado, K1
Alencar Filho, AC1
Kuehn, A1
Marques, MM1
Manso, MC1
Felger, I1
Vieira, JL1
Lameyre, V3
Daniel-Ribeiro, CT1
Lacerda, MV1
Happi, CT7
Carmona-Fonseca, J2
Arango, E1
Blair, S1
Clerk, CA1
Bruce, J1
Affipunguh, PK1
Mensah, N1
Hodgson, A2
Balogun, ST2
Hasugian, AR1
Tjitra, E1
Ratcliff, A1
Siswantoro, H1
Kenangalem, E1
Wuwung, RM1
Purba, HL1
Piera, KA1
Chalfien, F1
Marfurt, J1
Penttinen, PM1
Russell, B1
Anstey, NM1
Price, RN1
Tiono, AB1
Gansané, A1
Diarra, A1
Ouédraogo, A2
Konaté, AT1
Kiechel, JR1
Morgan, CC1
Olliaro, PL1
Taylor, WR2
Kiboi, DM1
Irungu, BN1
Langat, B1
Wittlin, S1
Brun, R1
Chollet, J1
Abiodun, O1
Nganga, JK1
Nyambati, VC1
Rukunga, GM1
Bell, A1
Nzila, A1
Ahorlu, CK2
Koram, KA2
Seakey, AK1
Weiss, MG2
Whegang, SY1
Tahar, R1
Foumane, VN1
Soula, G1
Gwét, H1
Thalabard, JC1
Bousema, T1
Okell, L1
Shekalaghe, S1
Griffin, JT1
Omar, S1
Sawa, P1
Sutherland, C1
Sauerwein, R1
Ghani, AC1
Drakeley, C1
Willcox, ML1
Graz, B1
Diakite, C1
Falquet, J1
Dackouo, F1
Sidibe, O1
Giani, S1
Diallo, D1
Michael, OS1
Oduola, AM3
Seake-Kwawu, A1
Okuboyejo, TM2
Faye, B3
Gueye, A1
Tine, R1
Tchania, C1
Ndiaye, I1
Cissé, B1
Gaye, O3
Dicko, M1
Diallo, AI1
Tembine, I1
Dicko, Y1
Dara, N1
Sidibe, Y1
Santara, G1
Conaré, T1
Cousens, S1
Milligan, PJ1
Diallo, DA1
Doumbo, OK1
Tine, RC1
Ndour, CT1
Ndiaye, M1
Bassene, C1
Magnussen, P1
Bygbjerg, IC1
Sylla, K1
Ndour, JD1
Arango, EM1
Upegui, YA1
Espié, E1
Lima, A1
Atua, B1
Dhorda, M1
Flévaud, L1
Sompwe, EM1
Palma Urrutia, PP1
Guerin, PJ1
Dorkenoo, MA1
Barrette, A1
Agbo, YM1
Bogreau, H1
Kutoati, S1
Sodahlon, YK1
Morgah, K1
Randrianarivelojosia, M1
Harisoa, JL1
Rabarijaona, LP1
Raharimalala, LA1
Ranaivo, L1
Pietra, V2
Duchemin, JB1
Rakotomanana, F1
Robert, V1
Mauclere, P1
Ariey, F1
Fateye, BA5
Barennes, H1
Nagot, N1
Koussoubé-Balima, T1
Sanou, T1
Yé, S1
Adedeji, AA5
Fehintola, FA3
Happi, TC3
Babalola, CP1
Oduro, AR1
Anyorigiya, T1
Ansah, P1
Anto, F1
Ansah, NA1
Atuguba, F1
Mumuni, G1
Amankwa, J1
Graupner, J1
Göbels, K1
Grobusch, MP1
Lund, A1
Richter, J1
Häussinger, D1
Tambo, E2
Adjetey, TA2
Affoumou, GB1
Loukou, DD1
Nebavi, NG2
Barro-Kiki, P1
Menan, EI2
Yavo, W2
Kone, M3
Patrick Kachur, S1
Schulden, J1
Goodman, CA1
Kassala, H1
Elling, BF1
Khatib, RA1
Causer, LM1
Mkikima, S1
Abdulla, S1
Bloland, PB1
Zurovac, D1
Midia, B1
Ochola, SA1
English, M1
Snow, RW1
Grandesso, F1
Hagerman, A1
Kamara, S1
Lam, E1
Checchi, F1
Balkan, S1
Scollo, G1
Durand, R1
Guthmann, JP1
van Doren, W1
Van Overmeir, C1
Ngamije, D1
Holmgren, G1
Björkman, A1
Gil, JP1
Ibrahium, AM1
Kheir, MM1
Osman, ME1
Khalil, IF1
Alifrangis, M1
Elmardi, KA1
Malik, EM1
Adam, I1
Rouamba, N1
Dokomajilar, C2
Guiguemde, RT1
Rosenthal, PJ2
Osorio, L1
Gonzalez, I1
Staedke, S1
Clark, TD1
Njama-Meya, D1
Nzarubara, B1
Maiteki-Sebuguzi, C1
Kamya, MR1
Ehrhardt, S1
Eggelte, TA1
Kaiser, S1
Adjei, L1
Burchard, GD1
Anemana, SD1
Bienzle, U1
Mockenhaupt, FP2
Diouf, AM1
Kuété, T1
Cisse, M1
Seck, PA1
Same-Ekobo, A1
Mandi, G1
Coulibaly, B1
Meissner, P1
Müller, O1
Del Nero, L1
Lamizana, L1
Nebié, I1
le Hesran, JY1
Boudin, C1
Cot, M1
Personne, P1
Chambon, R1
Foumane, V1
Verhave, JP1
de Vries, C1
al-Yaman, F1
Genton, B1
Mokela, D1
Narara, A1
Raiko, A1
Alpers, MP1
Adou-Bryn, KD1
Kouassi, D1
Ouhon, J1
Assoumou, A1
Gorissen, E1
Ashruf, G1
Lamboo, M1
Bennebroek, J1
Gikunda, S1
Mbaruku, G1
Kager, PA1
Collins, WE1
Sullivan, JS1
Fryauff, DJ1
Kendall, J1
Jennings, V1
Galland, GG1
Morris, CL1
Falade, AG1
Ndikum, VN1
Sowunmi, CO1
Falade, CO1
Guiyedi, V1
Koko, J1
Bouyou Akotet, M1
Mabika Manfoumbi, M1
Matsiégui, PB1
Traoré, B1
Kombila, M1
Barro-Kiki, PC1
Nigué, L1
Konan, YJ1

Clinical Trials (17)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
In Vivo Efficacy of Artemether-lumefantrine and Amodiaquine-artesunate for the Treatment of Uncomplicated Falciparum Malaria in Children: A Multisite Open Label, Two-cohort Clinical Trial in Mozambique[NCT04370977]Phase 4630 participants (Actual)Interventional2018-03-21Completed
Effect of Single-course Malaria Chemoprevention on Clearance of and Protection From Plasmodium Falciparum Infection in the Presence of Resistance-associated Genotypes in Cameroon[NCT06173206]Phase 3900 participants (Anticipated)Interventional2024-03-15Not yet recruiting
Randomized, Double-blind, Placebo-controlled, Multicenter, Multi-arm, Phase II Trial of Novel Agents for the Treatment of Mild to Moderate COVID-19 Positive Outpatients[NCT04530617]Phase 2246 participants (Actual)Interventional2020-10-05Terminated (stopped due to Results from the interim analysis)
A Trial of Seasonal Malaria Chemoprevention Plus Azithromycin in African Children[NCT02211729]Phase 322,090 participants (Actual)Interventional2014-05-31Completed
Artemether-Lumefantrine Resistance Monitoring in Children With Uncomplicated Plasmodium Falciparum Malaria in Mali[NCT02645604]154 participants (Actual)Observational2016-01-01Completed
Studies of Innate and Acquired Resistance to P. Falciparum Malaria in Mali[NCT00669084]1,718 participants (Actual)Observational2008-04-21Completed
Pharmacovigilance for Artemisinin-based Combination Treatments in Africa[NCT01232530]3,176 participants (Actual)Observational2010-06-30Completed
A Randomised Comparative Study to Assess the Efficacy and Tolerability of Blood Schizonticidal Treatments With Artesunate Amodiaquine Winthrop® / Coarsucam (ASAQ) Versus Chloroquine (CQ) for Uncomplicated Plasmodium Vivax Monoinfection Malaria[NCT01378286]Phase 3380 participants (Actual)Interventional2012-01-31Completed
Efficacy of Sulphadoxine-pyrimethamine and Amodiaquine Alone or in Combination as Intermittent Preventive Treatment in Pregnancy in the Kassena-Nankana District of Ghana: a Randomized Controlled Trial[NCT00146783]Phase 2/Phase 33,642 participants (Actual)Interventional2004-06-30Completed
Exploring the Impact of Scaling up Mass Testing, Treatment and Tracking on Malaria Prevalence Among Children in the Pakro Sub District of Ghana[NCT04167566]5,000 participants (Actual)Interventional2017-07-01Completed
Assessment of Antimalaria Drugs Susceptibility Testing for an Effective Management of Infected Patients in Sub-Sahara Africa[NCT02974348]Phase 3300 participants (Actual)Interventional2013-01-31Completed
Evaluation of the Efficacy and Safety of Primaquine for Clearance of Gametocytes in Uncomplicated Falciparum Malaria in Uganda[NCT01365598]Phase 3468 participants (Actual)Interventional2011-12-31Completed
Determining the Impact of Scaling up Mass Testing, Treatment and Tracking on Malaria Prevalence Among Children in the Pakro Sub District of Ghana[NCT04301531]5,861 participants (Actual)Interventional2020-03-01Completed
A Randomized Study to Compare Artesunate + Amiodaquine Versus Artemether + Lumefantrine in the Treatment of Repeated Uncomplicated Plasmodium Falciparum Malaria Attacks Occurring During 2 Years in a Cohort in Senegal[NCT00540410]Phase 4366 participants (Actual)Interventional2007-09-30Completed
A Trial of the Combined Impact of Intermittent Preventive Treatment and Insecticide Treated Bednets in Reducing Morbidity From Malaria in African Children[NCT00738946]6,000 participants (Anticipated)Interventional2008-08-31Completed
Efficacy of Amodiaquine-Artesunate and Artemether-Lumefantrine for the Treatment of Uncomplicated Childhood Plasmodium Falciparum Malaria in Pweto, Democratic Republic of Congo, 2008[NCT01567423]301 participants (Actual)Interventional2008-04-30Completed
Longitudinal Comparison of Combination Antimalarial Therapies in Ugandan Children: Evaluation of Safety, Tolerability, and Efficacy[NCT00123552]Phase 3601 participants (Actual)Interventional2004-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for amodiaquine and Parasitemia

ArticleYear
Intermittent preventive treatment for malaria in infants.
    The Cochrane database of systematic reviews, 2021, 07-17, Volume: 7

    Topics: Africa South of the Sahara; Amodiaquine; Antimalarials; Artemisinins; Bias; Confidence Intervals; Di

2021
Plasmodium falciparum clearance in clinical studies of artesunate-amodiaquine and comparator treatments in sub-Saharan Africa, 1999-2009.
    Malaria journal, 2014, Mar-25, Volume: 13

    Topics: Africa South of the Sahara; Amodiaquine; Antimalarials; Artemisinins; Drug Combinations; Humans; Kin

2014

Trials

38 trials available for amodiaquine and Parasitemia

ArticleYear
Artemisia annua and Artemisia afra tea infusions vs. artesunate-amodiaquine (ASAQ) in treating Plasmodium falciparum malaria in a large scale, double blind, randomized clinical trial.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 57

    Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Artemisia; Artemisia annua; Artemisinins; Child; Doub

2019
Efficacy of artemisinin combination therapy for the treatment of uncomplicated falciparum malaria in Nigerian children.
    Journal of infection in developing countries, 2013, Dec-15, Volume: 7, Issue:12

    Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, P

2013
Randomized comparison of the efficacies and tolerabilities of three artemisinin-based combination treatments for children with acute Plasmodium falciparum malaria in the Democratic Republic of the Congo.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:9

    Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschoo

2014
Efficacy of artemisinin-based combination treatments of uncomplicated falciparum malaria in under-five-year-old Nigerian children.
    The American journal of tropical medicine and hygiene, 2014, Volume: 91, Issue:5

    Topics: Amodiaquine; Anemia; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child,

2014
A randomized trial of artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in pregnancy.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2015, Volume: 131, Issue:1

    Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisini

2015
Fixed-Dose Artesunate-Amodiaquine Combination vs Chloroquine for Treatment of Uncomplicated Blood Stage P. vivax Infection in the Brazilian Amazon: An Open-Label Randomized, Controlled Trial.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017, Jan-15, Volume: 64, Issue:2

    Topics: Adolescent; Adult; Aged; Amodiaquine; Antimalarials; Artemisinins; Brazil; Child; Child, Preschool;

2017
[Gametocytemia in falciparum malaria treated with amodiaquine or artesunate].
    Biomedica : revista del Instituto Nacional de Salud, 2008, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Child, Preschool;

2008
A randomized, controlled trial of intermittent preventive treatment with sulfadoxine-pyrimethamine, amodiaquine, or the combination in pregnant women in Ghana.
    The Journal of infectious diseases, 2008, Oct-15, Volume: 198, Issue:8

    Topics: Amodiaquine; Anemia; Animals; Antimalarials; Child, Preschool; Drug Combinations; Drug Therapy, Comb

2008
The efficacy and safety of a new fixed-dose combination of amodiaquine and artesunate in young African children with acute uncomplicated Plasmodium falciparum.
    Malaria journal, 2009, Mar-16, Volume: 8

    Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Burkina Faso; Child, Preschool; Drug Combinations

2009
Effectiveness of combined intermittent preventive treatment for children and timely home treatment for malaria control.
    Malaria journal, 2009, Dec-11, Volume: 8

    Topics: Adult; Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Caregivers; Child, Preschool;

2009
Efficacy of non-artemisinin- and artemisinin-based combination therapies for uncomplicated falciparum malaria in Cameroon.
    Malaria journal, 2010, Feb-19, Volume: 9

    Topics: Administration, Oral; Amodiaquine; Antimalarials; Artemisinins; Cameroon; Child, Preschool; Drug Adm

2010
Is parasite clearance clinically important after malaria treatment in a high transmission area? A 3-month follow-up of home-based management with herbal medicine or ACT.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2011, Volume: 105, Issue:1

    Topics: Adolescent; Amodiaquine; Antimalarials; Argemone; Artemisinins; Child; Child, Preschool; Drug Combin

2011
Early variations in plasmodium falciparum dynamics in Nigerian children after treatment with two artemisinin-based combinations: implications on delayed parasite clearance.
    Malaria journal, 2010, Nov-22, Volume: 9

    Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Blood; Child; C

2010
Oral artesunate-amodiaquine and artemether-lumefantrine in the treatment of uncomplicated hyperparasitaemic Plasmodium falciparum malaria in children.
    Journal of tropical pediatrics, 2012, Volume: 58, Issue:2

    Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, P

2012
Repeated treatment of recurrent uncomplicated Plasmodium falciparum malaria in Senegal with fixed-dose artesunate plus amodiaquine versus fixed-dose artemether plus lumefantrine: a randomized, open-label trial.
    Malaria journal, 2011, Aug-12, Volume: 10

    Topics: Adolescent; Adult; Aged; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Arte

2011
Malaria morbidity in children in the year after they had received intermittent preventive treatment of malaria in Mali: a randomized control trial.
    PloS one, 2011, Volume: 6, Issue:8

    Topics: Amodiaquine; Anemia; Antimalarials; Body Weight; Child, Preschool; Drug Administration Schedule; Dru

2011
Impact of combining intermittent preventive treatment with home management of malaria in children less than 10 years in a rural area of Senegal: a cluster randomized trial.
    Malaria journal, 2011, Dec-13, Volume: 10

    Topics: Amodiaquine; Anemia; Animals; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; C

2011
Efficacy of different primaquine-based antimalarial regimens against Plasmodium falciparum gametocytemia.
    Acta tropica, 2012, Volume: 122, Issue:2

    Topics: Adolescent; Adult; Aged; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Prescho

2012
Efficacy of fixed-dose combination artesunate-amodiaquine versus artemether-lumefantrine for uncomplicated childhood Plasmodium falciparum malaria in Democratic Republic of Congo: a randomized non-inferiority trial.
    Malaria journal, 2012, May-25, Volume: 11

    Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschoo

2012
Plasmodium falciparum gametocytaemia in Nigerian children: before, during and after treatment with antimalarial drugs.
    Tropical medicine & international health : TM & IH, 2003, Volume: 8, Issue:9

    Topics: Age Factors; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combina

2003
A randomized trial of amodiaquine and artesunate alone and in combination for the treatment of uncomplicated falciparum malaria in children from Burkina Faso.
    Tropical medicine & international health : TM & IH, 2004, Volume: 9, Issue:4

    Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Double-Bl

2004
Risk factors for gametocyte carriage in uncomplicated falciparum malaria in children.
    Parasitology, 2004, Volume: 129, Issue:Pt 3

    Topics: Amodiaquine; Animals; Antimalarials; Carrier State; Child; Child, Preschool; Chloroquine; Chlorpheni

2004
Plasmodium falciparum hyperparasitaemia in children. Risk factors, treatment outcomes, and gametocytaemia following treatment.
    Parasite (Paris, France), 2004, Volume: 11, Issue:3

    Topics: Age Factors; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combina

2004
A randomized comparative study of chloroquine, amodiaquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated malaria in Ghana.
    Tropical medicine & international health : TM & IH, 2005, Volume: 10, Issue:3

    Topics: Amodiaquine; Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Female; Fever; Ghana;

2005
Open randomized study of artesunate-amodiaquine vs. chloroquine-pyrimethamine-sulfadoxine for the treatment of uncomplicated Plasmodium falciparum malaria in Nigerian children.
    Tropical medicine & international health : TM & IH, 2005, Volume: 10, Issue:11

    Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Com

2005
[Evaluation of the therapeutic efficacy of amodiaquine versus chloroquine in the treatment of uncomplicated malaria in Abie, Côte-d'Ivoire].
    Bulletin de la Societe de pathologie exotique (1990), 2005, Volume: 98, Issue:3

    Topics: Amodiaquine; Animals; Antimalarials; Child, Preschool; Chloroquine; Cote d'Ivoire; Drug Combinations

2005
A randomised trial to assess the safety and efficacy of artemether-lumefantrine (Coartem) for the treatment of uncomplicated Plasmodium falciparum malaria in Rwanda.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2007, Volume: 101, Issue:4

    Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschoo

2007
Amodiaquine resistance is not related to rare findings of pfmdr1 gene amplifications in Kenya.
    Tropical medicine & international health : TM & IH, 2006, Volume: 11, Issue:12

    Topics: Amodiaquine; Animals; Antimalarials; Child; Drug Resistance, Multiple; Follow-Up Studies; Gene Ampli

2006
Efficacies of artesunate plus either sulfadoxine-pyrimethamine or amodiaquine, for the treatment of uncomplicated, Plasmodium falciparum malaria in eastern Sudan.
    Annals of tropical medicine and parasitology, 2007, Volume: 101, Issue:1

    Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Comb

2007
Artemether-lumefantrine versus amodiaquine plus sulfadoxine-pyrimethamine for uncomplicated falciparum malaria in Burkina Faso: a randomised non-inferiority trial.
    Lancet (London, England), 2007, Feb-10, Volume: 369, Issue:9560

    Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Burkina Faso; C

2007
Artemisinin-based combination therapy for uncomplicated Plasmodium falciparum malaria in Colombia.
    Malaria journal, 2007, Feb-28, Volume: 6

    Topics: Adolescent; Adult; Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Bone Marrow Diseas

2007
Combination therapy for uncomplicated falciparum malaria in Ugandan children: a randomized trial.
    JAMA, 2007, May-23, Volume: 297, Issue:20

    Topics: Amodiaquine; Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesu

2007
Therapeutic efficacy and effects of artemether-lumefantrine and amodiaquine-sulfalene-pyrimethamine on gametocyte carriage in children with uncomplicated Plasmodium falciparum malaria in southwestern Nigeria.
    The American journal of tropical medicine and hygiene, 2007, Volume: 77, Issue:2

    Topics: Amodiaquine; Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child;

2007
Randomized, comparative study of the efficacy and safety of artesunate plus amodiaquine, administered as a single daily intake versus two daily intakes in the treatment of uncomplicated falciparum malaria.
    Malaria journal, 2008, Jan-19, Volume: 7

    Topics: Adolescent; Adult; Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Cameroon; Child; C

2008
Efficacy of amodiaquine in the treatment of uncomplicated falciparum malaria in young children of rural north-western Burkina Faso.
    Malaria journal, 2008, Apr-17, Volume: 7

    Topics: Amino Acid Substitution; Amodiaquine; Animals; Antimalarials; Burkina Faso; Child, Preschool; DNA, P

2008
[Clinical trial of amodiaquine in the community of Attécoubé (Abidjan, Côte d'Ivoire)(May-December 1955)].
    Bulletin de la Societe de pathologie exotique (1990), 2000, Volume: 93, Issue:2

    Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Cote d'Ivoire; Female; Humans; Malaria, Falciparum; M

2000
In vivo efficacy study of amodiaquine and sulfadoxine/ pyrimethamine in Kibwezi, Kenya and Kigoma, Tanzania.
    Tropical medicine & international health : TM & IH, 2000, Volume: 5, Issue:6

    Topics: Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Drug Resistance, Microbial; Female; Fe

2000
Randomized comparison of chloroquine and amodiaquine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children.
    Annals of tropical medicine and parasitology, 2001, Volume: 95, Issue:6

    Topics: Age Factors; Amodiaquine; Analysis of Variance; Antimalarials; Child; Child, Preschool; Chloroquine;

2001

Other Studies

35 other studies available for amodiaquine and Parasitemia

ArticleYear
Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium.
    Journal of medicinal chemistry, 2014, Nov-13, Volume: 57, Issue:21

    Topics: Animals; Antimalarials; Humans; Inhibitory Concentration 50; Malaria; Mice; Microsomes, Liver; Paras

2014
In vivo efficacy and safety of artemether-lumefantrine and amodiaquine-artesunate for uncomplicated Plasmodium falciparum malaria in Mozambique, 2018.
    Malaria journal, 2021, Oct-02, Volume: 20, Issue:1

    Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschoo

2021
Prevalence of malaria among febrile patients and assessment of efficacy of artemether-lumefantrine and artesunate-amodiaquine for uncomplicated malaria in Dolisie, Republic of the Congo.
    Malaria journal, 2022, May-02, Volume: 21, Issue:1

    Topics: Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artesunate; Child

2022
Variation in neutrophil levels and artemisinin-based combination therapy efficacy in West-Africa.
    Journal of infection in developing countries, 2023, 09-30, Volume: 17, Issue:9

    Topics: Africa; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesun

2023
Clinical illness and outcomes in Nigerian children with persistent early-appearing anaemia following initiation of artemisinin-based combination treatments of uncomplicated falciparum malaria.
    Parasite (Paris, France), 2019, Volume: 26

    Topics: Amodiaquine; Anemia; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child,

2019
Anaemia following Artemisinin-Based Combination Treatments of Uncomplicated Plasmodium falciparum Malaria in Children: Temporal Patterns of Haematocrit and the Use of Uncomplicated Hyperparasitaemia as a Model for Evaluating Late-Appearing Anaemia.
    Chemotherapy, 2017, Volume: 62, Issue:4

    Topics: Amodiaquine; Anemia; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child;

2017
Synthesis, β-hematin inhibition studies and antimalarial evaluation of new dehydroxy isoquine derivatives against Plasmodium berghei: A promising antimalarial agent.
    European journal of medicinal chemistry, 2018, Mar-25, Volume: 148

    Topics: Aminoquinolines; Amodiaquine; Animals; Antimalarials; Erythrocytes; Humans; Macrophages; Mice; Paras

2018
Efficacy and safety of artemether-lumefantrine, artesunate-amodiaquine, and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in three provinces in Angola, 2017.
    Malaria journal, 2018, Apr-03, Volume: 17, Issue:1

    Topics: Adolescent; Amodiaquine; Angola; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisin

2018
Efficacy of Artemisinin-Based Combination Treatments of Uncomplicated Falciparum Malaria in Under-Five-Year-Old Nigerian Children Ten Years Following Adoption as First-Line Antimalarials.
    The American journal of tropical medicine and hygiene, 2018, Volume: 99, Issue:3

    Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschoo

2018
Effect of Adding Azithromycin to Seasonal Malaria Chemoprevention.
    The New England journal of medicine, 2019, Jun-06, Volume: 380, Issue:23

    Topics: Amodiaquine; Anti-Bacterial Agents; Antimalarials; Azithromycin; Burkina Faso; Child Mortality; Chil

2019
Plasmodium falciparum clearance rates in response to artesunate in Malian children with malaria: effect of acquired immunity.
    The Journal of infectious diseases, 2013, Jun-01, Volume: 207, Issue:11

    Topics: Adaptive Immunity; Adolescent; Amodiaquine; Antibodies, Protozoan; Antimalarials; Artemisinins; Arte

2013
Plasmodium falciparum clearance rates in response to artesunate in Malian children with malaria: effect of acquired immunity.
    The Journal of infectious diseases, 2013, Jun-01, Volume: 207, Issue:11

    Topics: Adaptive Immunity; Adolescent; Amodiaquine; Antibodies, Protozoan; Antimalarials; Artemisinins; Arte

2013
Plasmodium falciparum clearance rates in response to artesunate in Malian children with malaria: effect of acquired immunity.
    The Journal of infectious diseases, 2013, Jun-01, Volume: 207, Issue:11

    Topics: Adaptive Immunity; Adolescent; Amodiaquine; Antibodies, Protozoan; Antimalarials; Artemisinins; Arte

2013
Plasmodium falciparum clearance rates in response to artesunate in Malian children with malaria: effect of acquired immunity.
    The Journal of infectious diseases, 2013, Jun-01, Volume: 207, Issue:11

    Topics: Adaptive Immunity; Adolescent; Amodiaquine; Antibodies, Protozoan; Antimalarials; Artemisinins; Arte

2013
Artesunate-Amodiaquine and Artemether-Lumefantrine Therapies and Selection of Pfcrt and Pfmdr1 Alleles in Nanoro, Burkina Faso.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Adult; Aged; Alleles; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemis

2016
Therapeutic efficacy and effects of artesunate-amodiaquine and artemether-lumefantrine on malaria-associated anaemia in Nigerian children aged two years and under.
    Infectious diseases of poverty, 2016, Jul-06, Volume: 5, Issue:1

    Topics: Amodiaquine; Anemia; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child,

2016
Early rising asexual parasitaemia in Nigerian children following a first dose of artemisinin-based combination treatments of falciparum malaria.
    BMC infectious diseases, 2017, 01-31, Volume: 17, Issue:1

    Topics: Administration, Oral; Adolescent; Amodiaquine; Antimalarials; Artemisinins; Child; Child Health Serv

2017
Plasmodium falciparum gametocyte sex ratios in children with acute, symptomatic, uncomplicated infections treated with amodiaquine.
    Malaria journal, 2008, Sep-02, Volume: 7

    Topics: Africa; Amodiaquine; Anemia; Animals; Child; Child, Preschool; Female; Humans; Infant; Kaplan-Meier

2008
In vivo and in vitro efficacy of amodiaquine monotherapy for treatment of infection by chloroquine-resistant Plasmodium vivax.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Adolescent; Age Distribution; Amodiaquine; Animals; Antimalarials; Chloroquine; Confidence Intervals

2009
Some features of primary and recrudescent amodiaquine-resistant Plasmodium falciparum infections in Nigerian children.
    Memorias do Instituto Oswaldo Cruz, 2008, Volume: 103, Issue:8

    Topics: Acute Disease; Amodiaquine; Animals; Antimalarials; Case-Control Studies; Child; Child, Preschool; D

2008
Plasmodium berghei ANKA: selection of resistance to piperaquine and lumefantrine in a mouse model.
    Experimental parasitology, 2009, Volume: 122, Issue:3

    Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Disease Models, Animal; Drug Resista

2009
Revisiting the circulation time of Plasmodium falciparum gametocytes: molecular detection methods to estimate the duration of gametocyte carriage and the effect of gametocytocidal drugs.
    Malaria journal, 2010, May-24, Volume: 9

    Topics: Adolescent; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Art

2010
Two-year evaluation of Intermittent Preventive Treatment for Children (IPTc) combined with timely home treatment for malaria control in Ghana.
    Malaria journal, 2011, May-15, Volume: 10

    Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chemoprevention; Child, Preschool; Drug Combinati

2011
Two-year evaluation of Intermittent Preventive Treatment for Children (IPTc) combined with timely home treatment for malaria control in Ghana.
    Malaria journal, 2011, May-15, Volume: 10

    Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chemoprevention; Child, Preschool; Drug Combinati

2011
Two-year evaluation of Intermittent Preventive Treatment for Children (IPTc) combined with timely home treatment for malaria control in Ghana.
    Malaria journal, 2011, May-15, Volume: 10

    Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chemoprevention; Child, Preschool; Drug Combinati

2011
Two-year evaluation of Intermittent Preventive Treatment for Children (IPTc) combined with timely home treatment for malaria control in Ghana.
    Malaria journal, 2011, May-15, Volume: 10

    Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chemoprevention; Child, Preschool; Drug Combinati

2011
Therapeutic efficacies of artemisinin-based combination therapies in Nigerian children with uncomplicated falciparum malaria during five years of adoption as first-line treatments.
    The American journal of tropical medicine and hygiene, 2011, Volume: 84, Issue:6

    Topics: Amodiaquine; Analysis of Variance; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemis

2011
Surveillance of the efficacy of artemether-lumefantrine and artesunate-amodiaquine for the treatment of uncomplicated Plasmodium falciparum among children under five in Togo, 2005-2009.
    Malaria journal, 2012, Oct-08, Volume: 11

    Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschoo

2012
In vitro sensitivity of Plasmodium falciparum to amodiaquine compared with other major antimalarials in Madagascar.
    Parassitologia, 2002, Volume: 44, Issue:3-4

    Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance; Drug Resistance, Multiple; Humans

2002
Rapid clearance of Plasmodium falciparum hyperparasitaemia after oral amodiaquine treatment in patients with uncomplicated malaria.
    Acta tropica, 2003, Volume: 88, Issue:1

    Topics: Administration, Oral; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Female; Humans;

2003
Efficacy of amodiaquine in uncomplicated falciparum malaria in Nigeria in an area with high-level resistance to chloroquine and sulphadoxine/pyrimethamine.
    Parasitology research, 2005, Volume: 96, Issue:3

    Topics: Amodiaquine; Animals; Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistan

2005
Prevalence of malaria parasitemia among clients seeking treatment for fever or malaria at drug stores in rural Tanzania 2004.
    Tropical medicine & international health : TM & IH, 2006, Volume: 11, Issue:4

    Topics: Adult; Amodiaquine; Analgesics, Non-Narcotic; Anemia; Antimalarials; Child, Preschool; Drug Combinat

2006
Microscopy and outpatient malaria case management among older children and adults in Kenya.
    Tropical medicine & international health : TM & IH, 2006, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Ambulatory Care; Amodiaquine; Antimalarials; Case Management; Child; Cross-Sectio

2006
Low efficacy of the combination artesunate plus amodiaquine for uncomplicated falciparum malaria among children under 5 years in Kailahun, Sierra Leone.
    Tropical medicine & international health : TM & IH, 2006, Volume: 11, Issue:7

    Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Drug Therapy, Combination; F

2006
Large-scale surveillance of Plasmodium falciparum crt(K76T) in northern Ghana.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9

    Topics: Adolescent; Adult; Aged; Amodiaquine; Animals; Antimalarials; Artemisinins; Child; Chloroquine; Drug

2007
Sensitivity to antimalarial drugs by Plasmodium falciparum in Goundry, Oubritenga province, Burkina Faso.
    Parassitologia, 1994, Volume: 36, Issue:3

    Topics: Amodiaquine; Animals; Antimalarials; Burkina Faso; Child; Child, Preschool; Chloroquine; Drug Resist

1994
In-vivo resistance of Plasmodium falciparum to chloroquine and amodiaquine in south Cameroon and age-related efficacy of the drugs.
    Annals of tropical medicine and parasitology, 1997, Volume: 91, Issue:6

    Topics: Adolescent; Age Factors; Amodiaquine; Animals; Antimalarials; Cameroon; Child; Child, Preschool; Chl

1997
Resistance of Plasmodium falciparum malaria to amodiaquine, chloroquine and quinine in the Madang Province of Papua New Guinea, 1990-1993.
    Papua and New Guinea medical journal, 1996, Volume: 39, Issue:1

    Topics: Acute Disease; Amodiaquine; Animals; Antimalarials; Case-Control Studies; Child; Child, Preschool; C

1996
Adaptation of a chloroquine-resistant strain of Plasmodium vivax from Indonesia to New World monkeys.
    The American journal of tropical medicine and hygiene, 2000, Volume: 62, Issue:4

    Topics: Adaptation, Physiological; Adult; Amodiaquine; Animals; Antimalarials; Aotidae; Child; Chloroquine;

2000
[Evaluation of efficacy and tolerance of amodiaquine versus chloroquine in the treatment of uncomplicated malaria outbreak in children of Gabon].
    Bulletin de la Societe de pathologie exotique (1990), 2001, Volume: 94, Issue:3

    Topics: Adolescent; Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Femal

2001
[In vivo sensitivity of Plasmodium falciparum to amino-4-quinolines and sulfadoxine pyrimethamine in Agou (Ivory Coast)].
    Pathologie-biologie, 2002, Volume: 50, Issue:3

    Topics: Adolescent; Aminoquinolines; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Cote d'Iv

2002