amodiaquine has been researched along with Long QT Syndrome in 3 studies
Amodiaquine: A 4-aminoquinoline compound with anti-inflammatory properties.
amodiaquine : A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position.
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These side effects include various mild heart rate changes (amodiaquine) to excessive prolongation of the QT interval (halofantrine) which may lead to lethal arrhythmias such as Torsade de Pointes (TdP)." | 4.82 | Antimalarial drugs: QT prolongation and cardiac arrhythmias. ( Dumotier, B; Traebert, M, 2005) |
| "Amodiaquine is a 4-aminoquinoline antimalarial similar to chloroquine that is used extensively for the treatment and prevention of malaria." | 2.72 | The cardiovascular effects of amodiaquine and structurally related antimalarials: An individual patient data meta-analysis. ( Ashley, EA; Chan, XHS; Djimdé, A; Fanello, CI; Haeusler, IL; Hanafiah, M; Hanboonkunupakarn, B; Kiechel, JR; Lacerda, MV; Lee, SJ; Ogutu, B; Onyamboko, MA; Pike, J; Siqueira, AM; Taylor, WR; White, NJ; Win, YN, 2021) |
| "There was no evidence of proarrhythmia with any treatment during the study although dihydroartemisinin-piperaquine, artesunate-amodiaquine and artemether-lumefantrine significantly prolonged QTc." | 1.51 | Evaluation of the effects on the QT-interval of 4 artemisinin-based combination therapies with a correction-free and heart rate-free method. ( Beavogui, AH; Borghini-Fuhrer, I; Djimdé, AA; Duparc, S; Felices, M; Funck-Brentano, C; Khan, Y; Ouedraogo, JB; Ouologuem, N; Sagara, I; Sirima, SB; Soulama, I; Voiriot, P, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Chan, XHS | 1 |
| Haeusler, IL | 1 |
| Win, YN | 1 |
| Pike, J | 1 |
| Hanboonkunupakarn, B | 1 |
| Hanafiah, M | 1 |
| Lee, SJ | 1 |
| Djimdé, A | 1 |
| Fanello, CI | 1 |
| Kiechel, JR | 1 |
| Lacerda, MV | 1 |
| Ogutu, B | 1 |
| Onyamboko, MA | 1 |
| Siqueira, AM | 1 |
| Ashley, EA | 1 |
| Taylor, WR | 1 |
| White, NJ | 1 |
| Funck-Brentano, C | 1 |
| Ouologuem, N | 1 |
| Duparc, S | 1 |
| Felices, M | 1 |
| Sirima, SB | 1 |
| Sagara, I | 1 |
| Soulama, I | 1 |
| Ouedraogo, JB | 1 |
| Beavogui, AH | 1 |
| Borghini-Fuhrer, I | 1 |
| Khan, Y | 1 |
| Djimdé, AA | 1 |
| Voiriot, P | 1 |
| Traebert, M | 1 |
| Dumotier, B | 1 |
2 reviews available for amodiaquine and Long QT Syndrome
| Article | Year |
|---|---|
The cardiovascular effects of amodiaquine and structurally related antimalarials: An individual patient data meta-analysis.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Bradycardia; Cardiotoxicity; Child; Child, Preschool; | 2021 |
Antimalarial drugs: QT prolongation and cardiac arrhythmias.
Topics: Amodiaquine; Drug Approval; Electrophysiology; Humans; Long QT Syndrome; Malaria; Phenanthrenes; Ris | 2005 |
1 other study available for amodiaquine and Long QT Syndrome
| Article | Year |
|---|---|
Evaluation of the effects on the QT-interval of 4 artemisinin-based combination therapies with a correction-free and heart rate-free method.
Topics: Adolescent; Amodiaquine; Antimalarials; Arrhythmias, Cardiac; Artemether; Artemether, Lumefantrine D | 2019 |