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amodiaquine and Itching

amodiaquine has been researched along with Itching in 4 studies

Amodiaquine: A 4-aminoquinoline compound with anti-inflammatory properties.
amodiaquine : A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position.

Research Excerpts

ExcerptRelevanceReference
"Amodiaquine+SP is not well tolerated and a substantial proportion of patients experienced pruritus and fatigue, thus decreasing their compliance and compromising the first line treatment implementation at national level."9.12Tolerability of amodiaquine and sulphadoxine-pyrimethamine, alone or in combination for the treatment of uncomplicated Plasmodium falciparum malaria in Rwandan adults. ( D'Alessandro, U; Fanello, CI; Karema, C; Rwagacondo, CE; van Doren, W, 2006)
"Amodiaquine+SP is not well tolerated and a substantial proportion of patients experienced pruritus and fatigue, thus decreasing their compliance and compromising the first line treatment implementation at national level."5.12Tolerability of amodiaquine and sulphadoxine-pyrimethamine, alone or in combination for the treatment of uncomplicated Plasmodium falciparum malaria in Rwandan adults. ( D'Alessandro, U; Fanello, CI; Karema, C; Rwagacondo, CE; van Doren, W, 2006)
"Using a presumptive animal model of the pruritus produced by chloroquine or amodiaquine in patients with malaria, the ability of mono de-ethylated chloroquine, chloroquine, mono de-ethylated amodiaquine, bi-de-ethylated amodiaquine and normal saline (placebo) to be differentiated in their pruritogenic potentials were determined."3.68Structure activity relationships in the pruritogenicity of chloroquine and amodiaquine metabolites in a dog model. ( Osifo, NG, 1991)
" The safety was evaluated by incidence of adverse events."2.73Randomized, comparative study of the efficacy and safety of artesunate plus amodiaquine, administered as a single daily intake versus two daily intakes in the treatment of uncomplicated falciparum malaria. ( Brasseur, P; Cisse, M; Diouf, AM; Faye, B; Gaye, O; Kuété, T; Lameyre, V; Ndiaye, JL; Same-Ekobo, A; Seck, PA, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fanello, CI1
Karema, C1
van Doren, W1
Rwagacondo, CE1
D'Alessandro, U1
Ndiaye, JL1
Faye, B1
Diouf, AM1
Kuété, T1
Cisse, M1
Seck, PA1
Brasseur, P1
Same-Ekobo, A1
Lameyre, V1
Gaye, O1
Olatunde, A1
Obih, PO1
Osifo, NG1

Trials

2 trials available for amodiaquine and Itching

ArticleYear
Tolerability of amodiaquine and sulphadoxine-pyrimethamine, alone or in combination for the treatment of uncomplicated Plasmodium falciparum malaria in Rwandan adults.
    Tropical medicine & international health : TM & IH, 2006, Volume: 11, Issue:5

    Topics: Adult; Amodiaquine; Antimalarials; Blood Cell Count; Double-Blind Method; Drug Combinations; Drug Th

2006
Randomized, comparative study of the efficacy and safety of artesunate plus amodiaquine, administered as a single daily intake versus two daily intakes in the treatment of uncomplicated falciparum malaria.
    Malaria journal, 2008, Jan-19, Volume: 7

    Topics: Adolescent; Adult; Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Cameroon; Child; C

2008

Other Studies

2 other studies available for amodiaquine and Itching

ArticleYear
Use and misuse of 4-aminoquinoline antimalarials in tropical Africa and re-examination of itch reaction to these drugs.
    Tropical doctor, 1981, Volume: 11, Issue:3

    Topics: Amodiaquine; Chloroquine; Health Surveys; Humans; Malaria; Nigeria; Pruritus

1981
Structure activity relationships in the pruritogenicity of chloroquine and amodiaquine metabolites in a dog model.
    Journal of dermatological science, 1991, Volume: 2, Issue:2

    Topics: Amodiaquine; Animals; Chloroquine; Dealkylation; Dogs; Female; Hindlimb; Ischemia; Male; Pruritus; S

1991