amodiaquine has been researched along with Innate Inflammatory Response in 6 studies
Amodiaquine: A 4-aminoquinoline compound with anti-inflammatory properties.
amodiaquine : A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amodiaquine is an antimalarial drug that causes life-threatening agranulocytosis and hepatotoxicity in about 1 in 2000 patients, which is usually associated with an inflammatory response." | 5.35 | Amodiaquine-induced oxidative stress in a hepatocyte inflammation model. ( O'Brien, PJ; Tafazoli, S, 2009) |
| " CF fortified with highly bioavailable iron improved iron status but not Hb concentration, despite three-monthly IPT of malaria." | 2.80 | The effect of iron-fortified complementary food and intermittent preventive treatment of malaria on anaemia in 12- to 36-month-old children: a cluster-randomised controlled trial. ( Adiossan, LG; Brittenham, GM; Diakité, VG; Glinz, D; Hurrell, RF; N'Goran, EK; Ouattara, M; Righetti, AA; Seifert, B; Utzinger, J; Wegmüller, R; Zimmermann, MB, 2015) |
| "Gastric ulcers were in four groups; Group I was administered Artesunate, group II received Artesunate-Amodiaquine, group III received Artemether-Lumefantrine, and group IV was a positive control (normal saline)." | 1.56 | Antimalarial combination therapies increase gastric ulcers through an imbalance of basic antioxidative-oxidative enzymes in male Wistar rats. ( Atusiimirwe, JK; Ayikobua, ET; Kalange, M; Kasolo, J; Kasozi, KI; Matama, K; Munanura, EI; Namulema, J; Nansunga, M; Okpanachi, AO; Semuyaba, I; Ssempijja, F; Zirintunda, G, 2020) |
| "Amodiaquine is an antimalarial drug that causes life-threatening agranulocytosis and hepatotoxicity in about 1 in 2000 patients, which is usually associated with an inflammatory response." | 1.35 | Amodiaquine-induced oxidative stress in a hepatocyte inflammation model. ( O'Brien, PJ; Tafazoli, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Kalange, M | 1 |
| Nansunga, M | 1 |
| Kasozi, KI | 1 |
| Kasolo, J | 1 |
| Namulema, J | 1 |
| Atusiimirwe, JK | 1 |
| Ayikobua, ET | 1 |
| Ssempijja, F | 1 |
| Munanura, EI | 1 |
| Matama, K | 1 |
| Semuyaba, I | 1 |
| Zirintunda, G | 1 |
| Okpanachi, AO | 1 |
| Mak, A | 1 |
| Cho, T | 1 |
| Uetrecht, J | 1 |
| Glinz, D | 1 |
| Hurrell, RF | 1 |
| Ouattara, M | 1 |
| Zimmermann, MB | 1 |
| Brittenham, GM | 1 |
| Adiossan, LG | 1 |
| Righetti, AA | 1 |
| Seifert, B | 1 |
| Diakité, VG | 1 |
| Utzinger, J | 1 |
| N'Goran, EK | 1 |
| Wegmüller, R | 1 |
| Tafazoli, S | 1 |
| O'Brien, PJ | 1 |
| BRANCENI, D | 1 |
| AZADIAN-BOULANGER, G | 1 |
| JEQUIER, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Aetiology, Prevention and Control of Anaemia in Sub-Saharan Africa - Work Package 2: Efficacy Study: Efficacy of 2 Iron Fortified Porridges and IPT for the Prevention of Anemia in Young Children in Côte d'Ivoire.[NCT01634945] | 629 participants (Actual) | Interventional | 2012-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for amodiaquine and Innate Inflammatory Response
| Article | Year |
|---|---|
The effect of iron-fortified complementary food and intermittent preventive treatment of malaria on anaemia in 12- to 36-month-old children: a cluster-randomised controlled trial.
Topics: Amodiaquine; Anemia; Antimalarials; Child, Preschool; Cote d'Ivoire; Diphosphates; Drug Combinations | 2015 |
5 other studies available for amodiaquine and Innate Inflammatory Response
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Antimalarial combination therapies increase gastric ulcers through an imbalance of basic antioxidative-oxidative enzymes in male Wistar rats.
Topics: Amodiaquine; Animals; Antimalarials; Artemether; Artesunate; Drug Therapy, Combination; Gastric Muco | 2020 |
Use of an animal model to test whether non-alcoholic fatty liver disease increases the risk of idiosyncratic drug-induced liver injury.
Topics: Amodiaquine; Animals; Antibodies, Blocking; Chemical and Drug Induced Liver Injury; Choline Deficien | 2018 |
Amodiaquine-induced oxidative stress in a hepatocyte inflammation model.
Topics: Amodiaquine; Animals; Antimalarials; Antioxidants; Cell Survival; Cyclic N-Oxides; Dose-Response Rel | 2009 |
[EXPERIMENTAL INFLAMMATION INDUCED BY A HEPARIN ANALOG. A TEST OF ANTI-INFLAMMATORY ACTIVITY].
Topics: Amodiaquine; Anti-Allergic Agents; Anti-Inflammatory Agents; Aspirin; Chemistry, Pharmaceutical; Col | 1964 |