Page last updated: 2024-10-22

amodiaquine and HIV Coinfection

amodiaquine has been researched along with HIV Coinfection in 4 studies

Amodiaquine: A 4-aminoquinoline compound with anti-inflammatory properties.
amodiaquine : A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position.

Research Excerpts

ExcerptRelevanceReference
"Artesunate plus amodiaquine was highly efficacious for malaria treatment in HIV-infected children but was associated with a high risk of neutropenia, especially in the context of concurrent antiretroviral use."9.13High risk of neutropenia in HIV-infected children following treatment with artesunate plus amodiaquine for uncomplicated malaria in Uganda. ( Achan, J; Charlebois, E; Dorsey, G; Gasasira, AF; Havlir, D; Kalyango, JN; Kamya, MR; Kekitiinwa, A; Mebrahtu, T; Rosenthal, PJ; Ruel, T; Staedke, SG, 2008)
"Artesunate plus amodiaquine was highly efficacious for malaria treatment in HIV-infected children but was associated with a high risk of neutropenia, especially in the context of concurrent antiretroviral use."5.13High risk of neutropenia in HIV-infected children following treatment with artesunate plus amodiaquine for uncomplicated malaria in Uganda. ( Achan, J; Charlebois, E; Dorsey, G; Gasasira, AF; Havlir, D; Kalyango, JN; Kamya, MR; Kekitiinwa, A; Mebrahtu, T; Rosenthal, PJ; Ruel, T; Staedke, SG, 2008)
"Artesunate plus amodiaquine is used for malaria treatment in regions with overlapping HIV endemicity."3.80Disposition of amodiaquine and desethylamodiaquine in HIV-infected Nigerian subjects on nevirapine-containing antiretroviral therapy. ( Adedeji, WA; Adewole, IF; Akinola, IT; Akinyinka, OO; Aweeka, FT; Darin, KM; Fehintola, FA; Lindegardh, N; Ma, Q; Morse, GD; Murphy, RL; Ojengbede, O; Parikh, S; Scarsi, KK; Taiwo, B; Tarning, J, 2014)
" Additionally, these models are able to identify patient characteristics that cause alterations in the expected PK/PD profiles and through simulations can recommend changes to dosing which compensate for the differences."2.72Malaria PK/PD and the Role Pharmacometrics Can Play in the Global Health Arena: Malaria Treatment Regimens for Vulnerable Populations. ( Hughes, E; Jagannathan, P; Mohamed Ali, A; Savic, RM; Wallender, E, 2021)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Hughes, E1
Wallender, E1
Mohamed Ali, A1
Jagannathan, P1
Savic, RM1
Scarsi, KK1
Fehintola, FA1
Ma, Q1
Aweeka, FT1
Darin, KM1
Morse, GD1
Akinola, IT1
Adedeji, WA1
Lindegardh, N1
Tarning, J1
Ojengbede, O1
Adewole, IF1
Taiwo, B1
Murphy, RL1
Akinyinka, OO1
Parikh, S1
Gasasira, AF1
Kamya, MR1
Achan, J1
Mebrahtu, T1
Kalyango, JN1
Ruel, T1
Charlebois, E1
Staedke, SG1
Kekitiinwa, A1
Rosenthal, PJ1
Havlir, D1
Dorsey, G1
Olliaro, P1

Reviews

1 review available for amodiaquine and HIV Coinfection

ArticleYear
Malaria PK/PD and the Role Pharmacometrics Can Play in the Global Health Arena: Malaria Treatment Regimens for Vulnerable Populations.
    Clinical pharmacology and therapeutics, 2021, Volume: 110, Issue:4

    Topics: Amodiaquine; Anti-HIV Agents; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins

2021

Trials

1 trial available for amodiaquine and HIV Coinfection

ArticleYear
High risk of neutropenia in HIV-infected children following treatment with artesunate plus amodiaquine for uncomplicated malaria in Uganda.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Apr-01, Volume: 46, Issue:7

    Topics: Amodiaquine; Anti-HIV Agents; Antimalarials; Artemisinins; Artesunate; Chemoprevention; Child; Child

2008

Other Studies

2 other studies available for amodiaquine and HIV Coinfection

ArticleYear
Disposition of amodiaquine and desethylamodiaquine in HIV-infected Nigerian subjects on nevirapine-containing antiretroviral therapy.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:5

    Topics: Adolescent; Adult; Amodiaquine; Anti-Retroviral Agents; Antimalarials; Antiretroviral Therapy, Highl

2014
Disease and drug interactions: treating malaria with artesunate plus amodiaquine in patients also receiving treatment for concomitant HIV infection.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Apr-01, Volume: 46, Issue:7

    Topics: Amodiaquine; Anti-HIV Agents; Antimalarials; Artemisinins; Artesunate; Drug Interactions; Drug Thera

2008