Page last updated: 2024-10-22

amodiaquine and Enlarged Spleen

amodiaquine has been researched along with Enlarged Spleen in 4 studies

Amodiaquine: A 4-aminoquinoline compound with anti-inflammatory properties.
amodiaquine : A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position.

Research Excerpts

ExcerptRelevanceReference
"The safety and efficacy of the two most widely used fixed-dose artemisinin-based combination therapies (ACT), artesunate-amodiaquine (ASAQ) and artemether-lumefantrine (AL) are well established for single episodes of uncomplicated Plasmodium falciparum malaria, but the effects of repeated, long-term use are not well documented."5.19Efficacy and safety of fixed-dose artesunate-amodiaquine vs. artemether-lumefantrine for repeated treatment of uncomplicated malaria in Ugandan children. ( Afizi, K; Fredrick, M; Kamya, MR; Lameyre, V; Lukwago, R; Talisuna, AO; Yeka, A, 2014)
"A village-based programme of presumptive treatment of fever, using voluntary village aides to dispense oral chloroquine or amodiaquine, was established in 1982 by the Papua New Guinea Institute of Medical Research (PNG IMR) in 35 rural villages or hamlets near Madang, on the north coast of PNG."3.67The role of voluntary village aides in the control of malaria by presumptive treatment of fever. 2. Impact on village health. ( Alpers, MP; Heywood, PF; Jolley, DJ; Moir, JS; Tulloch, JL; Vrbova, H, 1985)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yeka, A1
Lameyre, V1
Afizi, K1
Fredrick, M1
Lukwago, R1
Kamya, MR1
Talisuna, AO1
Hedman, P1
Brohult, J1
Forslund, J1
Sirleaf, V1
Bengtsson, E1
Moir, JS1
Tulloch, JL1
Vrbova, H1
Jolley, DJ1
Heywood, PF1
Alpers, MP1
Schneider, MD1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomised Study to Compare a Fixed Dose Combination of Artesunate Plus Amiodaquine (Coarsucam) Versus a Fixed Dose Combination of Artemether Plus Lumefantrine (Coartem) in the Treatment of Repeated Uncomplicated Plasmodium Falciparum Malaria Attacks Oc[NCT00699920]Phase 4413 participants (Actual)Interventional2008-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for amodiaquine and Enlarged Spleen

ArticleYear
Efficacy and safety of fixed-dose artesunate-amodiaquine vs. artemether-lumefantrine for repeated treatment of uncomplicated malaria in Ugandan children.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Child, Preschool; Data Collection; Drug Combin

2014

Other Studies

3 other studies available for amodiaquine and Enlarged Spleen

ArticleYear
A pocket of controlled malaria in a holoendemic region of West Africa.
    Annals of tropical medicine and parasitology, 1979, Volume: 73, Issue:4

    Topics: Amodiaquine; Anopheles; Child; Child, Preschool; Chloroquine; Costs and Cost Analysis; Humans; Liber

1979
The role of voluntary village aides in the control of malaria by presumptive treatment of fever. 2. Impact on village health.
    Papua and New Guinea medical journal, 1985, Volume: 28, Issue:4

    Topics: Adolescent; Amodiaquine; Child; Child, Preschool; Chloroquine; Community Health Workers; Fever; Huma

1985
Characteristics and cross-resistance patterns of chloroquine-resistant Plasmodium berghei infections in mice.
    Experimental parasitology, 1968, Volume: 23, Issue:1

    Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Dapsone; Drug Resistance, Microbial; Female; Hemat

1968