amodiaquine has been researched along with Body Weight in 15 studies
Amodiaquine: A 4-aminoquinoline compound with anti-inflammatory properties.
amodiaquine : A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A new dose regimen of artesunate and amodiaquine (NDRAA) based on age or body weight range was compared with standard dose regimen of artesunate and amodiaquine (SDRAA) calculated according to body weight and with fixed-dose artesunate-amodiaquine (FDAA) and artemether-lumefantrine (AL) in 304 children afflicted by malaria aged 15 years or younger." | 9.16 | A simple dose regimen of artesunate and amodiaquine based on age or body weight range for uncomplicated falciparum malaria in children: comparison of therapeutic efficacy with standard dose regimen of artesunate and amodiaquine and artemether-lumefantrin ( Adewoye, EO; Folarin, OO; Gbotosho, GO; Happi, CT; Okuboyejo, TM; Sowunmi, A, 2012) |
| "Sulfadoxine-pyrimethamine with amodiaquine (SP-AQ) is a highly efficacious regimen for intermittent preventive treatment to prevent malaria in children (IPTc), but the amodiaquine component is not always well tolerated." | 9.14 | Amodiaquine dosage and tolerability for intermittent preventive treatment to prevent malaria in children. ( Ba, EH; Cairns, M; Cames, C; Cisse, B; Gaye, O; Greenwood, BM; Milligan, PJ; Simondon, K; Sokhna, C; Trape, JF, 2010) |
| "Amodiaquine is effective for the treatment of Plasmodium vivax malaria, but there is little information on the pharmacokinetic and pharmacodynamic properties of amodiaquine in pregnant women with malaria." | 7.78 | Population pharmacokinetic and pharmacodynamic modeling of amodiaquine and desethylamodiaquine in women with Plasmodium vivax malaria during and after pregnancy. ( Bergstrand, M; Cammas, M; Chotsiri, P; Day, NP; Jullien, V; Lindegardh, N; McGready, R; Nosten, F; Rijken, MJ; Singhasivanon, P; Tarning, J; White, NJ, 2012) |
| "A new dose regimen of artesunate and amodiaquine (NDRAA) based on age or body weight range was compared with standard dose regimen of artesunate and amodiaquine (SDRAA) calculated according to body weight and with fixed-dose artesunate-amodiaquine (FDAA) and artemether-lumefantrine (AL) in 304 children afflicted by malaria aged 15 years or younger." | 5.16 | A simple dose regimen of artesunate and amodiaquine based on age or body weight range for uncomplicated falciparum malaria in children: comparison of therapeutic efficacy with standard dose regimen of artesunate and amodiaquine and artemether-lumefantrin ( Adewoye, EO; Folarin, OO; Gbotosho, GO; Happi, CT; Okuboyejo, TM; Sowunmi, A, 2012) |
| "A dose regimen of artesunate and amodiaquine based on arm span- or age range (DRAAAS), derived from a study of 1674 children, was compared with standard dose regimen of the same drugs calculated according to body weight (SDRAA) in 68 malarious children." | 5.16 | A simple dose regimen of artesunate and amodiaquine based on arm span- or age range for childhood falciparum malaria: a preliminary evaluation. ( Akinrinola, IA; Gbotosho, GO; Happi, CT; Okuboyejo, TM; Sowunmi, A, 2012) |
| "Sulfadoxine-pyrimethamine with amodiaquine (SP-AQ) is a highly efficacious regimen for intermittent preventive treatment to prevent malaria in children (IPTc), but the amodiaquine component is not always well tolerated." | 5.14 | Amodiaquine dosage and tolerability for intermittent preventive treatment to prevent malaria in children. ( Ba, EH; Cairns, M; Cames, C; Cisse, B; Gaye, O; Greenwood, BM; Milligan, PJ; Simondon, K; Sokhna, C; Trape, JF, 2010) |
| "Chloroquine and hydroxychloroquine effectively suppress rheumatoid arthritis with a superior benefit to risk ratio." | 5.05 | Antimalarial drugs for rheumatoid arthritis. ( Mackenzie, AH, 1983) |
| "Amodiaquine is effective for the treatment of Plasmodium vivax malaria, but there is little information on the pharmacokinetic and pharmacodynamic properties of amodiaquine in pregnant women with malaria." | 3.78 | Population pharmacokinetic and pharmacodynamic modeling of amodiaquine and desethylamodiaquine in women with Plasmodium vivax malaria during and after pregnancy. ( Bergstrand, M; Cammas, M; Chotsiri, P; Day, NP; Jullien, V; Lindegardh, N; McGready, R; Nosten, F; Rijken, MJ; Singhasivanon, P; Tarning, J; White, NJ, 2012) |
| "Several products of artesunate plus amodiaquine (AS + AQ) are being deployed in malaria-endemic countries for treating uncomplicated falciparum malaria but dosing accuracy and consequential effects on efficacy and tolerability have not been examined." | 2.74 | Dosing accuracy of artesunate and amodiaquine as treatment for falciparum malaria in Casamance, Senegal. ( Agnamey, P; Badiane, M; Brasseur, P; Cisse, M; Gaye, O; Olliaro, P; Taylor, WR; Vaillant, M, 2009) |
| " Suboptimal dosing in children may lead to treatment failure and increased resistance." | 1.48 | Population Pharmacokinetic Properties of Sulfadoxine and Pyrimethamine: a Pooled Analysis To Inform Optimal Dosing in African Children with Uncomplicated Malaria. ( Allen, EN; Barnes, KI; Bell, DJ; de Kock, M; Denti, P; Djimde, AA; Tarning, J; Tekete, MM; Ward, SA; Workman, L, 2018) |
| " Pharmacokinetic (PK) data informing the optimum dosing of these drug regimens is limited, especially in children." | 1.36 | Pharmacokinetics of artemether-lumefantrine and artesunate-amodiaquine in children in Kampala, Uganda. ( Annerberg, A; Aweeka, F; Clark, TD; Dorsey, G; Drysdale, T; German, P; Kalyango, JN; Kamya, MR; Lindegardh, N; McGee, B; Mwesigwa, J; Parikh, S; Rosenthal, PJ, 2010) |
| "To test a novel methodology to define age-based dosing regimens for the treatment of malaria with a new, user-friendly, blister-packaged fixed-dose combination of artesunate and amodiaquine." | 1.33 | Use of weight-for-age-data to optimize tablet strength and dosing regimens for a new fixed-dose artesunate-amodiaquine combination for treating falciparum malaria. ( Brasseur, P; Olliaro, PL; Taylor, W; ter Kuile, FO; Terlouw, DJ; White, NJ, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 10 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Kock, M | 1 |
| Tarning, J | 2 |
| Workman, L | 1 |
| Allen, EN | 1 |
| Tekete, MM | 1 |
| Djimde, AA | 2 |
| Bell, DJ | 1 |
| Ward, SA | 1 |
| Barnes, KI | 1 |
| Denti, P | 1 |
| Jung, HY | 1 |
| Kim, B | 1 |
| Ryu, HG | 1 |
| Ji, Y | 1 |
| Park, S | 1 |
| Choi, SH | 1 |
| Lee, D | 1 |
| Lee, IK | 1 |
| Kim, M | 1 |
| Lee, YJ | 1 |
| Song, W | 1 |
| Lee, YH | 1 |
| Choi, HJ | 1 |
| Hyun, CK | 1 |
| Holzapfel, WH | 1 |
| Kim, KT | 1 |
| Djimde, M | 1 |
| Samouda, H | 1 |
| Jacobs, J | 1 |
| Niangaly, H | 1 |
| Tekete, M | 1 |
| Sombie, SB | 1 |
| Mgina, EJ | 1 |
| Fofana, B | 1 |
| Sagara, I | 1 |
| Doumbo, OK | 2 |
| Vaillant, M | 2 |
| Brasseur, P | 2 |
| Agnamey, P | 1 |
| Gaye, O | 2 |
| Cisse, M | 1 |
| Badiane, M | 1 |
| Taylor, WR | 1 |
| Olliaro, P | 1 |
| Mwesigwa, J | 1 |
| Parikh, S | 1 |
| McGee, B | 1 |
| German, P | 1 |
| Drysdale, T | 1 |
| Kalyango, JN | 1 |
| Clark, TD | 1 |
| Dorsey, G | 1 |
| Lindegardh, N | 2 |
| Annerberg, A | 1 |
| Rosenthal, PJ | 1 |
| Kamya, MR | 1 |
| Aweeka, F | 1 |
| Cairns, M | 1 |
| Cisse, B | 1 |
| Sokhna, C | 1 |
| Cames, C | 1 |
| Simondon, K | 1 |
| Ba, EH | 1 |
| Trape, JF | 1 |
| Greenwood, BM | 2 |
| Milligan, PJ | 3 |
| Gbotosho, GO | 2 |
| Sowunmi, A | 2 |
| Okuboyejo, TM | 2 |
| Happi, CT | 2 |
| Folarin, OO | 1 |
| Adewoye, EO | 1 |
| Konaté, AT | 1 |
| Yaro, JB | 1 |
| Ouédraogo, AZ | 1 |
| Diarra, A | 1 |
| Gansané, A | 1 |
| Soulama, I | 1 |
| Kangoyé, DT | 1 |
| Kaboré, Y | 1 |
| Ouédraogo, E | 1 |
| Ouédraogo, A | 1 |
| Tiono, AB | 1 |
| Ouédraogo, IN | 1 |
| Chandramohan, D | 2 |
| Cousens, S | 2 |
| Sirima, SB | 1 |
| Diallo, DA | 2 |
| Dicko, A | 1 |
| Barry, A | 1 |
| Dicko, M | 1 |
| Diallo, AI | 1 |
| Tembine, I | 1 |
| Dicko, Y | 1 |
| Dara, N | 1 |
| Sidibe, Y | 1 |
| Santara, G | 1 |
| Conaré, T | 1 |
| Greenwood, B | 1 |
| Akinrinola, IA | 1 |
| Chotsiri, P | 1 |
| Jullien, V | 1 |
| Rijken, MJ | 1 |
| Bergstrand, M | 1 |
| Cammas, M | 1 |
| McGready, R | 1 |
| Singhasivanon, P | 1 |
| Day, NP | 1 |
| White, NJ | 2 |
| Nosten, F | 1 |
| Taylor, W | 1 |
| Terlouw, DJ | 1 |
| Olliaro, PL | 1 |
| ter Kuile, FO | 1 |
| Mackenzie, AH | 1 |
| Shute, GT | 1 |
| Ray, AP | 1 |
| Sangalang, R | 1 |
| Elko, EE | 1 |
| Cantrell, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Single-course Malaria Chemoprevention on Clearance of and Protection From Plasmodium Falciparum Infection in the Presence of Resistance-associated Genotypes in Cameroon[NCT06173206] | Phase 3 | 900 participants (Anticipated) | Interventional | 2024-03-15 | Not yet recruiting | ||
| A Trial of the Combined Impact of Intermittent Preventive Treatment and Insecticide Treated Bednets in Reducing Morbidity From Malaria in African Children[NCT00738946] | 6,000 participants (Anticipated) | Interventional | 2008-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 trials available for amodiaquine and Body Weight
| Article | Year |
|---|---|
Dosing accuracy of artesunate and amodiaquine as treatment for falciparum malaria in Casamance, Senegal.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Body Weight; Child; Child, | 2009 |
Amodiaquine dosage and tolerability for intermittent preventive treatment to prevent malaria in children.
Topics: Age Factors; Amodiaquine; Antimalarials; Body Weight; Child; Child, Preschool; Dose-Response Relatio | 2010 |
A simple dose regimen of artesunate and amodiaquine based on age or body weight range for uncomplicated falciparum malaria in children: comparison of therapeutic efficacy with standard dose regimen of artesunate and amodiaquine and artemether-lumefantrin
Topics: Administration, Oral; Adolescent; Age Factors; Amodiaquine; Antimalarials; Artemether, Lumefantrine | 2012 |
Morbidity from malaria in children in the year after they had received intermittent preventive treatment of malaria: a randomised trial.
Topics: Amodiaquine; Anemia; Antimalarials; Body Weight; Burkina Faso; Child, Preschool; Double-Blind Method | 2011 |
Malaria morbidity in children in the year after they had received intermittent preventive treatment of malaria in Mali: a randomized control trial.
Topics: Amodiaquine; Anemia; Antimalarials; Body Weight; Child, Preschool; Drug Administration Schedule; Dru | 2011 |
A simple dose regimen of artesunate and amodiaquine based on arm span- or age range for childhood falciparum malaria: a preliminary evaluation.
Topics: Adolescent; Age Distribution; Amodiaquine; Antimalarials; Area Under Curve; Arm; Artemisinins; Artes | 2012 |
Antimalarial drugs for rheumatoid arthritis.
Topics: Amodiaquine; Antimalarials; Arthritis, Rheumatoid; Body Weight; Chloroquine; Clinical Trials as Topi | 1983 |
8 other studies available for amodiaquine and Body Weight
| Article | Year |
|---|---|
Population Pharmacokinetic Properties of Sulfadoxine and Pyrimethamine: a Pooled Analysis To Inform Optimal Dosing in African Children with Uncomplicated Malaria.
Topics: Africa; Age Factors; Amodiaquine; Antimalarials; Biomarkers, Pharmacological; Body Weight; Chemoprev | 2018 |
Amodiaquine improves insulin resistance and lipid metabolism in diabetic model mice.
Topics: 3T3-L1 Cells; Amodiaquine; Animals; Antimalarials; Blood Glucose; Body Weight; Cell Proliferation; D | 2018 |
Relationship between weight status and anti-malarial drug efficacy and safety in children in Mali.
Topics: Adolescent; Amodiaquine; Antimalarials; Artesunate; Body Weight; Child; Child, Preschool; Clinical T | 2019 |
Pharmacokinetics of artemether-lumefantrine and artesunate-amodiaquine in children in Kampala, Uganda.
Topics: Amodiaquine; Antimalarials; Area Under Curve; Artemether; Artemisinins; Artesunate; Biotransformatio | 2010 |
Population pharmacokinetic and pharmacodynamic modeling of amodiaquine and desethylamodiaquine in women with Plasmodium vivax malaria during and after pregnancy.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Biotransformation; Body Weight; Drug Administration S | 2012 |
Use of weight-for-age-data to optimize tablet strength and dosing regimens for a new fixed-dose artesunate-amodiaquine combination for treating falciparum malaria.
Topics: Adolescent; Age Distribution; Amodiaquine; Antimalarials; Artemisinins; Body Weight; Child; Child, P | 2006 |
Preliminary studies on a Philippine strain of Plasmodium falciparum resistant to amodiaquine.
Topics: Adult; Amodiaquine; Body Weight; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Phi | 1972 |
Nonspecific phagocytic activity in rats infected with Plasmodium berghei and treated with amodiaquine or chloroquine.
Topics: Amodiaquine; Animals; Body Weight; Carbon; Chloroquine; Colloids; Injections, Intravenous; Liver; Lu | 1970 |