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amodiaquine and Acute Disease

amodiaquine has been researched along with Acute Disease in 15 studies

Amodiaquine: A 4-aminoquinoline compound with anti-inflammatory properties.
amodiaquine : A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position.

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
"The treatment efficacy of artesunate-amodiaquine (AQ) coformulated or copackaged, and the plasma and saliva concentrations of desethylamodiaquine (DEAQ), the active metabolite of AQ, were evaluated in 120 and 7 children, respectively, with uncomplicated Plasmodium falciparum malaria treated with oral daily doses of the 2 formulations for 3 days."9.17Therapeutic efficacy of artesunate-amodiaquine combinations and the plasma and saliva concentrations of desethylamodiaquine in children with acute uncomplicated Plasmodium falciparum malaria. ( Adewoye, EO; Folarin, O; Gbotosho, GO; Happi, CT; Michael, OS; Okuboyejo, TM; Sijuade, AO; Sowunmi, A, 2013)
"The effects of chloroquine (CQ), amodiaquine (AQ) and CQ plus chlorpheniramine (a histamine H(1) antagonist that reverses CQ resistance in vitro and in vivo) on the disposition of the enlarged liver associated with acute, symptomatic, uncomplicated, Plasmodium falciparum malaria were evaluated."9.10The effects of chloroquine, amodiaquine and chloroquine plus chlorpheniramine on the disposition kinetics of the hepatomegaly associated with acute, uncomplicated, Plasmodium falciparum malaria in children. ( Adedeji, AA; Sowunmi, A, 2002)
" In the present study, the efficacies of chloroquine (CQ) or amodiaquine (AQ) in the oral treatment of acute, symptomatic, uncomplicated, Plasmodium falciparum malaria were compared with those of oral treatments with the combination of CQ or AQ with pyrimethamine-sulfadoxine (PS)."9.10A randomized comparison of chloroquine, amodiaquine and their combination with pyrimethamine-sulfadoxine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children. ( Sowunmi, A, 2002)
"6 out of 7 patients with severe neutropenia associated with the use of amodiaquine for malaria prophylaxis amodiaquine (400 mg weekly) plus proguanil (200 mg daily); 1 of these patients had also taken cotrimoxazole and another had taken sulphaguanidine."7.67Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria. ( Bunch, C; Edwards, G; Hatton, CS; Pasvol, G; Peto, TE; Russell, SJ; Singer, CR; Winstanley, P, 1986)
" The findings indicate that - at least at the dosing regimen used in the present study and among children with acute, uncomplicated, P."6.71A randomized comparison of chloroquine and chloroquine plus ketotifen in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children. ( Sowunmi, A, 2003)
"Atovaquone and proguanil was a highly effective and safe drug combination in patients with acute uncomplicated P falciparum malaria in Gabon."6.68Atovaquone and proguanil for Plasmodium falciparum malaria. ( Hutchinson, D; Kremsner, PG; Nkeyi, M; Philipps, J; Radloff, PD, 1996)
"The treatment efficacy of artesunate-amodiaquine (AQ) coformulated or copackaged, and the plasma and saliva concentrations of desethylamodiaquine (DEAQ), the active metabolite of AQ, were evaluated in 120 and 7 children, respectively, with uncomplicated Plasmodium falciparum malaria treated with oral daily doses of the 2 formulations for 3 days."5.17Therapeutic efficacy of artesunate-amodiaquine combinations and the plasma and saliva concentrations of desethylamodiaquine in children with acute uncomplicated Plasmodium falciparum malaria. ( Adewoye, EO; Folarin, O; Gbotosho, GO; Happi, CT; Michael, OS; Okuboyejo, TM; Sijuade, AO; Sowunmi, A, 2013)
"The effects of chloroquine (CQ), amodiaquine (AQ) and CQ plus chlorpheniramine (a histamine H(1) antagonist that reverses CQ resistance in vitro and in vivo) on the disposition of the enlarged liver associated with acute, symptomatic, uncomplicated, Plasmodium falciparum malaria were evaluated."5.10The effects of chloroquine, amodiaquine and chloroquine plus chlorpheniramine on the disposition kinetics of the hepatomegaly associated with acute, uncomplicated, Plasmodium falciparum malaria in children. ( Adedeji, AA; Sowunmi, A, 2002)
" In the present study, the efficacies of chloroquine (CQ) or amodiaquine (AQ) in the oral treatment of acute, symptomatic, uncomplicated, Plasmodium falciparum malaria were compared with those of oral treatments with the combination of CQ or AQ with pyrimethamine-sulfadoxine (PS)."5.10A randomized comparison of chloroquine, amodiaquine and their combination with pyrimethamine-sulfadoxine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children. ( Sowunmi, A, 2002)
"6 out of 7 patients with severe neutropenia associated with the use of amodiaquine for malaria prophylaxis amodiaquine (400 mg weekly) plus proguanil (200 mg daily); 1 of these patients had also taken cotrimoxazole and another had taken sulphaguanidine."3.67Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria. ( Bunch, C; Edwards, G; Hatton, CS; Pasvol, G; Peto, TE; Russell, SJ; Singer, CR; Winstanley, P, 1986)
" The findings indicate that - at least at the dosing regimen used in the present study and among children with acute, uncomplicated, P."2.71A randomized comparison of chloroquine and chloroquine plus ketotifen in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children. ( Sowunmi, A, 2003)
"Atovaquone and proguanil was a highly effective and safe drug combination in patients with acute uncomplicated P falciparum malaria in Gabon."2.68Atovaquone and proguanil for Plasmodium falciparum malaria. ( Hutchinson, D; Kremsner, PG; Nkeyi, M; Philipps, J; Radloff, PD, 1996)
"Recrudescence was detected by a thick blood smear and confirmed by polymerase chain reaction."1.35Some features of primary and recrudescent amodiaquine-resistant Plasmodium falciparum infections in Nigerian children. ( Balogun, ST; Gbotosho, GO; Happi, CT; Sowunmi, A, 2008)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19905 (33.33)18.7374
1990's3 (20.00)18.2507
2000's6 (40.00)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sowunmi, A7
Balogun, ST1
Gbotosho, GO3
Happi, CT2
Okuboyejo, TM1
Sijuade, AO1
Michael, OS1
Adewoye, EO1
Folarin, O1
Adedeji, AA2
Fateye, BA1
Happi, TC1
Falade, CO1
Michael, SO1
Oduola, AM1
Radloff, PD1
Philipps, J1
Nkeyi, M1
Hutchinson, D1
Kremsner, PG1
al-Yaman, F1
Genton, B1
Mokela, D1
Narara, A1
Raiko, A1
Alpers, MP1
Salako, LA1
Hatton, CS1
Peto, TE1
Bunch, C1
Pasvol, G1
Russell, SJ1
Singer, CR1
Edwards, G1
Winstanley, P1
Amouretti, M1
Raymond, JM1
Baldit, C1
Dumas, F1
Couzigou, P1
BĂ©raud, C1
Rieckmann, KH1
Myint, UH1
Win, UK1
Bruce-Chwatt, LJ1

Reviews

1 review available for amodiaquine and Acute Disease

ArticleYear
Resistance of P. falciparum to chloroquine in Africa: true or false?
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1970, Volume: 64, Issue:5

    Topics: Acute Disease; Africa; Amodiaquine; Antimalarials; Chloroquine; Proguanil

1970

Trials

7 trials available for amodiaquine and Acute Disease

ArticleYear
Therapeutic efficacy of artesunate-amodiaquine combinations and the plasma and saliva concentrations of desethylamodiaquine in children with acute uncomplicated Plasmodium falciparum malaria.
    American journal of therapeutics, 2013, Volume: 20, Issue:1

    Topics: Acute Disease; Administration, Oral; Amodiaquine; Antimalarials; Artemisinins; Child; Child, Prescho

2013
The effects of chloroquine, amodiaquine and chloroquine plus chlorpheniramine on the disposition kinetics of the hepatomegaly associated with acute, uncomplicated, Plasmodium falciparum malaria in children.
    Annals of tropical medicine and parasitology, 2002, Volume: 96, Issue:6

    Topics: Acute Disease; Adolescent; Amodiaquine; Antimalarials; Area Under Curve; Child; Child, Preschool; Ch

2002
A randomized comparison of chloroquine and chloroquine plus ketotifen in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children.
    Annals of tropical medicine and parasitology, 2003, Volume: 97, Issue:2

    Topics: Acute Disease; Administration, Oral; Amodiaquine; Analysis of Variance; Antimalarials; Child; Child,

2003
Enhanced efficacy of amodiaquine and chlorpheniramine combination over amodiaquine alone in the treatment of acute uncomplicated Plasmodium falciparum malaria in children.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2008, Volume: 17, Issue:3

    Topics: Acute Disease; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chlorpheniramine; Drug

2008
Atovaquone and proguanil for Plasmodium falciparum malaria.
    Lancet (London, England), 1996, Jun-01, Volume: 347, Issue:9014

    Topics: Acute Disease; Adult; Amodiaquine; Antimalarials; Atovaquone; Drug Administration Schedule; Drug The

1996
A randomized comparison of chloroquine, amodiaquine and their combination with pyrimethamine-sulfadoxine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children.
    Annals of tropical medicine and parasitology, 2002, Volume: 96, Issue:3

    Topics: Acute Disease; Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Therapy, Combi

2002
Evaluation of the relative efficacy of various antimalarial drugs in Nigerian children under five years of age suffering from acute uncomplicated falciparum malaria.
    Annals of tropical medicine and parasitology, 1992, Volume: 86, Issue:1

    Topics: Acute Disease; Amodiaquine; Antimalarials; Child, Preschool; Chloroquine; Drug Administration Schedu

1992

Other Studies

7 other studies available for amodiaquine and Acute Disease

ArticleYear
Some features of primary and recrudescent amodiaquine-resistant Plasmodium falciparum infections in Nigerian children.
    Memorias do Instituto Oswaldo Cruz, 2008, Volume: 103, Issue:8

    Topics: Acute Disease; Amodiaquine; Animals; Antimalarials; Case-Control Studies; Child; Child, Preschool; D

2008
Effects of pyrimethamine-sulphadoxine, chloroquine plus chlorpheniramine, and amodiaquine plus pyrimethamine-sulphadoxine on gametocytes during and after treatment of acute, uncomplicated malaria in children.
    Memorias do Instituto Oswaldo Cruz, 2006, Volume: 101, Issue:8

    Topics: Acute Disease; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Chlorpheni

2006
Resistance of Plasmodium falciparum malaria to amodiaquine, chloroquine and quinine in the Madang Province of Papua New Guinea, 1990-1993.
    Papua and New Guinea medical journal, 1996, Volume: 39, Issue:1

    Topics: Acute Disease; Amodiaquine; Animals; Antimalarials; Case-Control Studies; Child; Child, Preschool; C

1996
Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria.
    Lancet (London, England), 1986, Feb-22, Volume: 1, Issue:8478

    Topics: Acute Disease; Adult; Agranulocytosis; Amodiaquine; Drug Combinations; Drug Therapy, Combination; Fe

1986
[Amodiaquine (Flavoquine) is hepatotoxic].
    Gastroenterologie clinique et biologique, 1986, Volume: 10, Issue:12

    Topics: Acute Disease; Adult; Amodiaquine; Chemical and Drug Induced Liver Injury; Female; Humans

1986
Determination of the drug sensitivity of Plasmodium falciparum.
    JAMA, 1971, Aug-02, Volume: 217, Issue:5

    Topics: Acute Disease; Amodiaquine; Antimalarials; Chloroquine; Drug Resistance, Microbial; Folic Acid Antag

1971
The routine treatment of malaria.
    Tropical doctor, 1971, Volume: 1, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Amodiaquine; Child; Child, Preschool; Chloroquine; Chronic Disease

1971