amodiaquine has been researched along with Acute Disease in 15 studies
Amodiaquine: A 4-aminoquinoline compound with anti-inflammatory properties.
amodiaquine : A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The treatment efficacy of artesunate-amodiaquine (AQ) coformulated or copackaged, and the plasma and saliva concentrations of desethylamodiaquine (DEAQ), the active metabolite of AQ, were evaluated in 120 and 7 children, respectively, with uncomplicated Plasmodium falciparum malaria treated with oral daily doses of the 2 formulations for 3 days." | 9.17 | Therapeutic efficacy of artesunate-amodiaquine combinations and the plasma and saliva concentrations of desethylamodiaquine in children with acute uncomplicated Plasmodium falciparum malaria. ( Adewoye, EO; Folarin, O; Gbotosho, GO; Happi, CT; Michael, OS; Okuboyejo, TM; Sijuade, AO; Sowunmi, A, 2013) |
| "The effects of chloroquine (CQ), amodiaquine (AQ) and CQ plus chlorpheniramine (a histamine H(1) antagonist that reverses CQ resistance in vitro and in vivo) on the disposition of the enlarged liver associated with acute, symptomatic, uncomplicated, Plasmodium falciparum malaria were evaluated." | 9.10 | The effects of chloroquine, amodiaquine and chloroquine plus chlorpheniramine on the disposition kinetics of the hepatomegaly associated with acute, uncomplicated, Plasmodium falciparum malaria in children. ( Adedeji, AA; Sowunmi, A, 2002) |
| " In the present study, the efficacies of chloroquine (CQ) or amodiaquine (AQ) in the oral treatment of acute, symptomatic, uncomplicated, Plasmodium falciparum malaria were compared with those of oral treatments with the combination of CQ or AQ with pyrimethamine-sulfadoxine (PS)." | 9.10 | A randomized comparison of chloroquine, amodiaquine and their combination with pyrimethamine-sulfadoxine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children. ( Sowunmi, A, 2002) |
| "6 out of 7 patients with severe neutropenia associated with the use of amodiaquine for malaria prophylaxis amodiaquine (400 mg weekly) plus proguanil (200 mg daily); 1 of these patients had also taken cotrimoxazole and another had taken sulphaguanidine." | 7.67 | Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria. ( Bunch, C; Edwards, G; Hatton, CS; Pasvol, G; Peto, TE; Russell, SJ; Singer, CR; Winstanley, P, 1986) |
| " The findings indicate that - at least at the dosing regimen used in the present study and among children with acute, uncomplicated, P." | 6.71 | A randomized comparison of chloroquine and chloroquine plus ketotifen in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children. ( Sowunmi, A, 2003) |
| "Atovaquone and proguanil was a highly effective and safe drug combination in patients with acute uncomplicated P falciparum malaria in Gabon." | 6.68 | Atovaquone and proguanil for Plasmodium falciparum malaria. ( Hutchinson, D; Kremsner, PG; Nkeyi, M; Philipps, J; Radloff, PD, 1996) |
| "The treatment efficacy of artesunate-amodiaquine (AQ) coformulated or copackaged, and the plasma and saliva concentrations of desethylamodiaquine (DEAQ), the active metabolite of AQ, were evaluated in 120 and 7 children, respectively, with uncomplicated Plasmodium falciparum malaria treated with oral daily doses of the 2 formulations for 3 days." | 5.17 | Therapeutic efficacy of artesunate-amodiaquine combinations and the plasma and saliva concentrations of desethylamodiaquine in children with acute uncomplicated Plasmodium falciparum malaria. ( Adewoye, EO; Folarin, O; Gbotosho, GO; Happi, CT; Michael, OS; Okuboyejo, TM; Sijuade, AO; Sowunmi, A, 2013) |
| "The effects of chloroquine (CQ), amodiaquine (AQ) and CQ plus chlorpheniramine (a histamine H(1) antagonist that reverses CQ resistance in vitro and in vivo) on the disposition of the enlarged liver associated with acute, symptomatic, uncomplicated, Plasmodium falciparum malaria were evaluated." | 5.10 | The effects of chloroquine, amodiaquine and chloroquine plus chlorpheniramine on the disposition kinetics of the hepatomegaly associated with acute, uncomplicated, Plasmodium falciparum malaria in children. ( Adedeji, AA; Sowunmi, A, 2002) |
| " In the present study, the efficacies of chloroquine (CQ) or amodiaquine (AQ) in the oral treatment of acute, symptomatic, uncomplicated, Plasmodium falciparum malaria were compared with those of oral treatments with the combination of CQ or AQ with pyrimethamine-sulfadoxine (PS)." | 5.10 | A randomized comparison of chloroquine, amodiaquine and their combination with pyrimethamine-sulfadoxine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children. ( Sowunmi, A, 2002) |
| "6 out of 7 patients with severe neutropenia associated with the use of amodiaquine for malaria prophylaxis amodiaquine (400 mg weekly) plus proguanil (200 mg daily); 1 of these patients had also taken cotrimoxazole and another had taken sulphaguanidine." | 3.67 | Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria. ( Bunch, C; Edwards, G; Hatton, CS; Pasvol, G; Peto, TE; Russell, SJ; Singer, CR; Winstanley, P, 1986) |
| " The findings indicate that - at least at the dosing regimen used in the present study and among children with acute, uncomplicated, P." | 2.71 | A randomized comparison of chloroquine and chloroquine plus ketotifen in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children. ( Sowunmi, A, 2003) |
| "Atovaquone and proguanil was a highly effective and safe drug combination in patients with acute uncomplicated P falciparum malaria in Gabon." | 2.68 | Atovaquone and proguanil for Plasmodium falciparum malaria. ( Hutchinson, D; Kremsner, PG; Nkeyi, M; Philipps, J; Radloff, PD, 1996) |
| "Recrudescence was detected by a thick blood smear and confirmed by polymerase chain reaction." | 1.35 | Some features of primary and recrudescent amodiaquine-resistant Plasmodium falciparum infections in Nigerian children. ( Balogun, ST; Gbotosho, GO; Happi, CT; Sowunmi, A, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (33.33) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sowunmi, A | 7 |
| Balogun, ST | 1 |
| Gbotosho, GO | 3 |
| Happi, CT | 2 |
| Okuboyejo, TM | 1 |
| Sijuade, AO | 1 |
| Michael, OS | 1 |
| Adewoye, EO | 1 |
| Folarin, O | 1 |
| Adedeji, AA | 2 |
| Fateye, BA | 1 |
| Happi, TC | 1 |
| Falade, CO | 1 |
| Michael, SO | 1 |
| Oduola, AM | 1 |
| Radloff, PD | 1 |
| Philipps, J | 1 |
| Nkeyi, M | 1 |
| Hutchinson, D | 1 |
| Kremsner, PG | 1 |
| al-Yaman, F | 1 |
| Genton, B | 1 |
| Mokela, D | 1 |
| Narara, A | 1 |
| Raiko, A | 1 |
| Alpers, MP | 1 |
| Salako, LA | 1 |
| Hatton, CS | 1 |
| Peto, TE | 1 |
| Bunch, C | 1 |
| Pasvol, G | 1 |
| Russell, SJ | 1 |
| Singer, CR | 1 |
| Edwards, G | 1 |
| Winstanley, P | 1 |
| Amouretti, M | 1 |
| Raymond, JM | 1 |
| Baldit, C | 1 |
| Dumas, F | 1 |
| Couzigou, P | 1 |
| Béraud, C | 1 |
| Rieckmann, KH | 1 |
| Myint, UH | 1 |
| Win, UK | 1 |
| Bruce-Chwatt, LJ | 1 |
1 review available for amodiaquine and Acute Disease
| Article | Year |
|---|---|
Resistance of P. falciparum to chloroquine in Africa: true or false?
Topics: Acute Disease; Africa; Amodiaquine; Antimalarials; Chloroquine; Proguanil | 1970 |
7 trials available for amodiaquine and Acute Disease
| Article | Year |
|---|---|
Therapeutic efficacy of artesunate-amodiaquine combinations and the plasma and saliva concentrations of desethylamodiaquine in children with acute uncomplicated Plasmodium falciparum malaria.
Topics: Acute Disease; Administration, Oral; Amodiaquine; Antimalarials; Artemisinins; Child; Child, Prescho | 2013 |
The effects of chloroquine, amodiaquine and chloroquine plus chlorpheniramine on the disposition kinetics of the hepatomegaly associated with acute, uncomplicated, Plasmodium falciparum malaria in children.
Topics: Acute Disease; Adolescent; Amodiaquine; Antimalarials; Area Under Curve; Child; Child, Preschool; Ch | 2002 |
A randomized comparison of chloroquine and chloroquine plus ketotifen in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children.
Topics: Acute Disease; Administration, Oral; Amodiaquine; Analysis of Variance; Antimalarials; Child; Child, | 2003 |
Enhanced efficacy of amodiaquine and chlorpheniramine combination over amodiaquine alone in the treatment of acute uncomplicated Plasmodium falciparum malaria in children.
Topics: Acute Disease; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chlorpheniramine; Drug | 2008 |
Atovaquone and proguanil for Plasmodium falciparum malaria.
Topics: Acute Disease; Adult; Amodiaquine; Antimalarials; Atovaquone; Drug Administration Schedule; Drug The | 1996 |
A randomized comparison of chloroquine, amodiaquine and their combination with pyrimethamine-sulfadoxine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children.
Topics: Acute Disease; Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Therapy, Combi | 2002 |
Evaluation of the relative efficacy of various antimalarial drugs in Nigerian children under five years of age suffering from acute uncomplicated falciparum malaria.
Topics: Acute Disease; Amodiaquine; Antimalarials; Child, Preschool; Chloroquine; Drug Administration Schedu | 1992 |
7 other studies available for amodiaquine and Acute Disease
| Article | Year |
|---|---|
Some features of primary and recrudescent amodiaquine-resistant Plasmodium falciparum infections in Nigerian children.
Topics: Acute Disease; Amodiaquine; Animals; Antimalarials; Case-Control Studies; Child; Child, Preschool; D | 2008 |
Effects of pyrimethamine-sulphadoxine, chloroquine plus chlorpheniramine, and amodiaquine plus pyrimethamine-sulphadoxine on gametocytes during and after treatment of acute, uncomplicated malaria in children.
Topics: Acute Disease; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Chlorpheni | 2006 |
Resistance of Plasmodium falciparum malaria to amodiaquine, chloroquine and quinine in the Madang Province of Papua New Guinea, 1990-1993.
Topics: Acute Disease; Amodiaquine; Animals; Antimalarials; Case-Control Studies; Child; Child, Preschool; C | 1996 |
Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria.
Topics: Acute Disease; Adult; Agranulocytosis; Amodiaquine; Drug Combinations; Drug Therapy, Combination; Fe | 1986 |
[Amodiaquine (Flavoquine) is hepatotoxic].
Topics: Acute Disease; Adult; Amodiaquine; Chemical and Drug Induced Liver Injury; Female; Humans | 1986 |
Determination of the drug sensitivity of Plasmodium falciparum.
Topics: Acute Disease; Amodiaquine; Antimalarials; Chloroquine; Drug Resistance, Microbial; Folic Acid Antag | 1971 |
The routine treatment of malaria.
Topics: Acute Disease; Adolescent; Adult; Amodiaquine; Child; Child, Preschool; Chloroquine; Chronic Disease | 1971 |