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amobarbital and Sclerosis

amobarbital has been researched along with Sclerosis in 16 studies

Amobarbital: A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
amobarbital : A member of the class of barbiturates that is pyrimidine-2,4,6(1H,3H,5H)-trione substituted by a 3-methylbutyl and an ethyl group at position 5. Amobarbital has been shown to exhibit sedative and hypnotic properties.

Sclerosis: A pathological process consisting of hardening or fibrosis of an anatomical structure, often a vessel or a nerve.

Research Excerpts

ExcerptRelevanceReference
"The goal of this study was to explore the relationship between language and memory lateralization in patients with epilepsy undergoing the intracarotid amobarbital procedure."3.75Memory performance is related to language dominance as determined by the intracarotid amobarbital procedure. ( Alexopoulos, AV; Kovac, S; Lineweaver, T; Loddenkemper, T; Möddel, G; Reinholz, J; Schuele, SU; Syed, T, 2009)
"The aim of this study was to determine whether the predictive value of the intracarotid amobarbital test (IAT) for the side to be resected is applicable only to medial temporal lobe epilepsy and to investigate whether there are different patterns of memory performances on the IAT between patients with unilateral mesial temporal sclerosis (UMT group) and those without (non-UMT group)."3.70Lateralized memory deficits on the Wada test correlate with the side of lobectomy only for patients with unilateral medial temporal lobe epilepsy. ( Hayashi, K; Kakeuchi, J; Kanemoto, K; Kawasaki, J; Kubo, H; Morimura, T; Takenouchi, K, 1999)
"Fifty-five percent had a history of febrile seizures."2.69Presurgical evaluation and surgical outcome of temporal lobe epilepsy. ( Asconape, J; Azzarelli, B; Garg, B; Hutchins, GD; Markand, O; Park, HM; Patel, H; Salanova, V; Smith, R; Worth, R, 1999)
"MRI-HS correlated with a history of febrile seizures and pathologically demonstrated hippocampal sclerosis."1.30FDG-PET and MRI in temporal lobe epilepsy: relationship to febrile seizures, hippocampal sclerosis and outcome. ( Azzarelli, B; Ghetti, B; Hutchins, G; Markand, O; Park, H; Salanova, V; Smith, R; Wellman, H; Worth, R, 1998)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (68.75)18.2507
2000's4 (25.00)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kovac, S1
Möddel, G1
Reinholz, J1
Alexopoulos, AV2
Syed, T1
Schuele, SU1
Lineweaver, T1
Loddenkemper, T2
Rathore, C1
George, A1
Kesavadas, C1
Sarma, PS1
Radhakrishnan, K1
Das, RR1
Loring, DW1
Meador, KJ1
Lee, GP1
Smith, JR1
Thadani, VM1
Williamson, PD1
Berger, R1
Spencer, SS1
Spencer, DD1
Novelly, RA1
Sass, KJ1
Kim, JH1
Mattson, RH1
Caner-Cukiert, AR1
Cukiert, A1
Gronich, G1
Marino Júnior, R1
Davies, KG3
Hermann, BP2
Foley, KT1
Carpenter, K1
Oxbury, JM1
Oxbury, S1
Wright, GD1
Salanova, V2
Markand, O2
Worth, R2
Smith, R2
Wellman, H1
Hutchins, G1
Park, H1
Ghetti, B1
Azzarelli, B2
Baxendale, SA1
Van Paesschen, W1
Thompson, PJ1
Duncan, JS1
Shorvon, SD1
Connelly, A1
Bell, BD2
Dohan, FC1
Schweitzer, JB1
Garg, B1
Patel, H1
Asconape, J1
Park, HM1
Hutchins, GD1
Son, YJ1
Chung, CK1
Lee, SK1
Chang, KH1
Lee, DS1
Yi, YN1
Kim, HJ1
Kanemoto, K1
Kawasaki, J1
Takenouchi, K1
Hayashi, K1
Kubo, H1
Morimura, T1
Kakeuchi, J1
Haltiner, AM1
Walters, GL1
Gates, JR1
Cruz-Rodriguez, R1

Reviews

1 review available for amobarbital and Sclerosis

ArticleYear
Mesial temporal sclerosis: pathogenesis, diagnosis, and management.
    Epilepsia, 1990, Volume: 31 Suppl 3

    Topics: Adolescent; Adult; Amobarbital; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Mag

1990

Trials

2 trials available for amobarbital and Sclerosis

ArticleYear
Results from the intracarotid amytal procedure in patients with uni or bitemporal lobe epilepsy and mesial sclerosis.
    Arquivos de neuro-psiquiatria, 1995, Volume: 53, Issue:3-B

    Topics: Amobarbital; Animals; Carotid Artery, Internal; Electroencephalography; Epilepsy, Temporal Lobe; Fun

1995
Presurgical evaluation and surgical outcome of temporal lobe epilepsy.
    Pediatric neurology, 1999, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Age Factors; Amobarbital; Brain Diseases; Brain Neoplasms; Child; Electroencephal

1999

Other Studies

13 other studies available for amobarbital and Sclerosis

ArticleYear
Memory performance is related to language dominance as determined by the intracarotid amobarbital procedure.
    Epilepsy & behavior : E&B, 2009, Volume: 16, Issue:1

    Topics: Adult; Amobarbital; Brain Neoplasms; Carotid Arteries; Cerebral Angiography; Cerebral Cortex; Epilep

2009
Extent of initial injury determines language lateralization in mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS).
    Epilepsia, 2009, Volume: 50, Issue:10

    Topics: Adult; Amobarbital; Brain Injuries; Brain Mapping; Electroencephalography; Epilepsy, Temporal Lobe;

2009
Incidence and clinical decision making for the Wada test over one decade: 1997-2007.
    Epileptic disorders : international epilepsy journal with videotape, 2010, Volume: 12, Issue:4

    Topics: Adolescent; Adult; Aged; Amobarbital; Child; Child, Preschool; Electrodes, Implanted; Epilepsy, Temp

2010
Structural versus functional prediction of memory change following anterior temporal lobectomy.
    Epilepsy & behavior : E&B, 2004, Volume: 5, Issue:2

    Topics: Adult; Amobarbital; Anterior Temporal Lobectomy; Dominance, Cerebral; Epilepsy, Temporal Lobe; Follo

2004
Successful epilepsy surgery without intracranial EEG recording: criteria for patient selection.
    Epilepsia, 1995, Volume: 36, Issue:1

    Topics: Adolescent; Adult; Amobarbital; Electroencephalography; Epilepsy, Complex Partial; Female; Follow-Up

1995
Relation between intracarotid amobarbital memory asymmetry scores and hippocampal sclerosis in patients undergoing anterior temporal lobe resections.
    Epilepsia, 1996, Volume: 37, Issue:6

    Topics: Adolescent; Adult; Amobarbital; Epilepsy; Female; Functional Laterality; Gliosis; Hippocampus; Human

1996
Memory for objects presented early after intracarotid sodium amytal: a sensitive clinical neuropsychological indicator of temporal lobe pathology.
    Seizure, 1996, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Amobarbital; Female; Functional Laterality; Hippocampus; Humans; Male; Memory Dis

1996
FDG-PET and MRI in temporal lobe epilepsy: relationship to febrile seizures, hippocampal sclerosis and outcome.
    Acta neurologica Scandinavica, 1998, Volume: 97, Issue:3

    Topics: Adolescent; Adult; Amobarbital; Atrophy; Carotid Artery, Internal; Child; Electroencephalography; Ep

1998
The relation between quantitative MRI measures of hippocampal structure and the intracarotid amobarbital test.
    Epilepsia, 1997, Volume: 38, Issue:9

    Topics: Adult; Amobarbital; Brain; Carotid Artery, Internal; Epilepsy, Temporal Lobe; Functional Laterality;

1997
Prediction of presence of hippocampal sclerosis from intracarotid amobarbital procedure memory asymmetry scores and epilepsy on set age.
    Epilepsy research, 1999, Volume: 33, Issue:2-3

    Topics: Adult; Age of Onset; Amobarbital; Carotid Arteries; Dominance, Cerebral; Epilepsy, Temporal Lobe; Fe

1999
Comparison of localizing values of various diagnostic tests in non-lesional medial temporal lobe epilepsy.
    Seizure, 1999, Volume: 8, Issue:8

    Topics: Adolescent; Adult; Algorithms; Amobarbital; Amygdala; Child; Cognition Disorders; Electroencephalogr

1999
Lateralized memory deficits on the Wada test correlate with the side of lobectomy only for patients with unilateral medial temporal lobe epilepsy.
    Seizure, 1999, Volume: 8, Issue:8

    Topics: Adult; Amobarbital; Electroencephalography; Epilepsy, Temporal Lobe; Female; Functional Laterality;

1999
Intracarotid amobarbital procedure and prediction of postoperative memory in patients with left temporal lobe epilepsy and hippocampal sclerosis.
    Epilepsia, 2000, Volume: 41, Issue:8

    Topics: Adult; Amobarbital; Brain Diseases; Carotid Artery, Internal; Epilepsy, Temporal Lobe; Female; Hippo

2000