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amobarbital and Pregnancy

amobarbital has been researched along with Pregnancy in 22 studies

Amobarbital: A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
amobarbital : A member of the class of barbiturates that is pyrimidine-2,4,6(1H,3H,5H)-trione substituted by a 3-methylbutyl and an ethyl group at position 5. Amobarbital has been shown to exhibit sedative and hypnotic properties.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Plasma half-lives of amobarbital were determined in newborn children of 10 mothers who had been treated with barbiturates for hypertension in pregnancy for 6 to 42 days prior to delivery."7.65Maternal and neonatal elimination of amobarbital after treatment of the mother with barbiturates during late pregnancy. ( Clare, RA; Darling, M; Davies, DS; Dollery, CT; Draffan, GH; Hawkins, DF; Krauer, B; Sertel, H; Trudinger, BJ; Williams, FM, 1976)
"Seventy unwed pregnant patients in states of mild to moderate depression evidenced by one or more symptoms (tenseness, "nervousness," crying spells, listlessness, fatigue, nausea and vomiting, insomnia and overeating), received informal psychotherapy and a sustained-release capsule combining d-amphetamine sulfate and amobarbital."7.63Prepartum depression; a study of seventy unwed mothers treated with d-amphetamine sulfate and amobarbital. ( CALDWELL, WG; NOWERS, W, 1958)
"Plasma half-lives of amobarbital were determined in newborn children of 10 mothers who had been treated with barbiturates for hypertension in pregnancy for 6 to 42 days prior to delivery."3.65Maternal and neonatal elimination of amobarbital after treatment of the mother with barbiturates during late pregnancy. ( Clare, RA; Darling, M; Davies, DS; Dollery, CT; Draffan, GH; Hawkins, DF; Krauer, B; Sertel, H; Trudinger, BJ; Williams, FM, 1976)
"Seventy unwed pregnant patients in states of mild to moderate depression evidenced by one or more symptoms (tenseness, "nervousness," crying spells, listlessness, fatigue, nausea and vomiting, insomnia and overeating), received informal psychotherapy and a sustained-release capsule combining d-amphetamine sulfate and amobarbital."3.63Prepartum depression; a study of seventy unwed mothers treated with d-amphetamine sulfate and amobarbital. ( CALDWELL, WG; NOWERS, W, 1958)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199021 (95.45)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Petik, D1
Czeizel, B1
Banhidy, F1
Czeizel, AE1
ALDER, S2
CALDWELL, WG1
NOWERS, W1
BOCS, G1
DEVENYI, I1
LAWSON, JG1
NEWTON, M1
PLASTYNOV, AB1
Kalow, W3
Towers, SH1
McMullin, GP1
Kadar, D1
Inaba, T2
Tang, BK1
Endrenyi, L1
Ginsberg, L1
Hillman, N1
Draffan, GH2
Dollery, CT1
Davies, DS1
Krauer, B1
Williams, FM2
Clare, RA2
Trudinger, BJ1
Darling, M1
Sertel, H1
Hawkins, DF1
MacGillivray, I1
Campbell, M1
Breuer, H1
Wolman, SR1
Luck, VR1
Kikuchi, Y1
Lauersen, NH1
Fuchs, F1
Burke, M1
Marks, J1
Goodlin, RC1
Gillessen, H1

Trials

1 trial available for amobarbital and Pregnancy

ArticleYear
Controlled trial of antenatal barbiturates in rhesus haemolytic disease.
    Archives of disease in childhood, 1977, Volume: 52, Issue:4

    Topics: Amobarbital; Clinical Trials as Topic; Erythroblastosis, Fetal; Female; Humans; Infant, Newborn; Mat

1977

Other Studies

21 other studies available for amobarbital and Pregnancy

ArticleYear
A study of the risk of mental retardation among children of pregnant women who have attempted suicide by means of a drug overdose.
    Journal of injury & violence research, 2012, Volume: 4, Issue:1

    Topics: Abnormalities, Drug-Induced; Adult; Amobarbital; Birth Weight; Chi-Square Distribution; Drug Combina

2012
[Management of hyperemesis gravidarum with metrotonin and phenothiazine].
    Munchener medizinische Wochenschrift (1950), 1956, Dec-28, Volume: 98, Issue:52

    Topics: Amobarbital; Female; Hyperemesis Gravidarum; Methamphetamine; Phenothiazines; Pregnancy; Sympathomim

1956
[Management of hyperemesis gravidarum with metrotonin and phenothiazine].
    Munchener medizinische Wochenschrift (1950), 1956, Dec-28, Volume: 98, Issue:52

    Topics: Amobarbital; Female; Hyperemesis Gravidarum; Methamphetamine; Phenothiazines; Pregnancy; Sympathomim

1956
[Management of hyperemesis gravidarum with metrotonin and phenothiazine].
    Munchener medizinische Wochenschrift (1950), 1956, Dec-28, Volume: 98, Issue:52

    Topics: Amobarbital; Female; Hyperemesis Gravidarum; Methamphetamine; Phenothiazines; Pregnancy; Sympathomim

1956
[Management of hyperemesis gravidarum with metrotonin and phenothiazine].
    Munchener medizinische Wochenschrift (1950), 1956, Dec-28, Volume: 98, Issue:52

    Topics: Amobarbital; Female; Hyperemesis Gravidarum; Methamphetamine; Phenothiazines; Pregnancy; Sympathomim

1956
Prepartum depression; a study of seventy unwed mothers treated with d-amphetamine sulfate and amobarbital.
    California medicine, 1958, Volume: 88, Issue:5

    Topics: Amobarbital; Amphetamine; Amphetamines; Anxiety; Apathy; Depression; Depressive Disorder; Dextroamph

1958
[Megimide therapy of severe Dorlotyn intoxication during the 5th month of pregnancy].
    Pathologie et biologie, 1962, Jan-21, Volume: 103

    Topics: Amobarbital; Bemegride; Central Nervous System Stimulants; Pregnancy; Pregnancy Complications

1962
TOXAEMIA OF PREGNANCY.
    The Practitioner, 1964, Volume: 192

    Topics: Albuminuria; Amobarbital; Blood Pressure; Edema; Female; Humans; Labor, Induced; Morphine; Paraldehy

1964
THE CONTINUING PROBLEM OF ECLAMPSIA.
    Surgery, gynecology & obstetrics, 1964, Volume: 118

    Topics: Amobarbital; Antihypertensive Agents; Cesarean Section; Eclampsia; Female; Humans; Hydralazine; Hype

1964
[Treatment of threatened abortion with pharmacological sleep with the use of medinal and urethane].
    Azerbaidzhanskii meditsinskii zhurnal = Aserbaidschanische medizinische Zeitschrift, 1961, Volume: 5

    Topics: Abortion, Induced; Abortion, Spontaneous; Abortion, Threatened; Amobarbital; Barbital; Female; Human

1961
Search for single gene effects in multifactorial inheritance in pharmacogenetics.
    Human genetics. Supplement, 1978, Issue:1

    Topics: Amobarbital; Antipyrine; Enzymes; Female; Genes; Humans; Male; Pregnancy; Twins, Dizygotic; Twins, M

1978
A case of deficiency of N-hydroxylation of amobarbital.
    Clinical pharmacology and therapeutics, 1977, Volume: 21, Issue:5

    Topics: Adolescent; Adult; Aged; Alleles; Amobarbital; Biotransformation; Female; Half-Life; Humans; Hydroxy

1977
Genetic study of amobarbital elimination based on its kinetics in twins.
    Clinical pharmacology and therapeutics, 1976, Volume: 20, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Amobarbital; Female; Half-Life; Humans; Injections, Intrave

1976
Shifts in ATP synthesis during preimplantation stages of mouse embryos.
    Journal of reproduction and fertility, 1975, Volume: 43, Issue:1

    Topics: Adenosine Triphosphate; Amobarbital; Animals; Antimycin A; Binding Sites; Blastocyst; Cyanides; Embr

1975
Maternal and neonatal elimination of amobarbital after treatment of the mother with barbiturates during late pregnancy.
    Clinical pharmacology and therapeutics, 1976, Volume: 19, Issue:3

    Topics: Adult; Amobarbital; Barbiturates; Female; Half-Life; Humans; Hypertension; Infant, Newborn; Kinetics

1976
Treatment of severe toxaemia of pregnancy.
    Lancet (London, England), 1972, Jan-22, Volume: 1, Issue:7743

    Topics: Amobarbital; Birth Weight; Cevanes; Chlormethiazole; Female; Furosemide; Gestational Age; Heparin; H

1972
The interplay of biological and environmental factors in a preschool-age patient with Klinefelter's syndrome. Case report.
    Pediatrics, 1973, Volume: 52, Issue:1

    Topics: Abnormalities, Drug-Induced; Amobarbital; Child Behavior Disorders; Child, Preschool; Dermatoglyphic

1973
Oral contraceptives.
    The Medical journal of Australia, 1966, Nov-05, Volume: 2, Issue:19

    Topics: Adult; Amobarbital; Chlormadinone Acetate; Contraceptives, Oral; Female; Humans; Mestranol; Methenam

1966
Dynamics of pyridine nucleotide in the placenta and the effect on it of sexagens.
    Acta obstetrica et gynaecologica Japonica, 1969, Volume: 16, Issue:4

    Topics: Abortion, Spontaneous; Amobarbital; Animals; Centrifugation; Delivery, Obstetric; Estradiol; Female;

1969
Experience with Shirodkar's operation and postoperative alcohol treatment.
    Acta obstetricia et gynecologica Scandinavica, 1973, Volume: 52, Issue:1

    Topics: Abortion, Threatened; Amobarbital; Delivery, Obstetric; Ethanol; Female; Fetal Death; Gestational Ag

1973
Purpura associated with vomiting in pregnancy.
    British medical journal, 1973, May-26, Volume: 2, Issue:5864

    Topics: Amobarbital; Female; Humans; Pregnancy; Pregnancy Complications; Purpura; Vomiting

1973
Determination of barbiturates and their metabolites in small plasma samples by gas chromatography-mass spectrometry. Amylorbarbitone and 3'-hydroxyamylobarbitone.
    Journal of chromatography, 1973, Jan-03, Volume: 75, Issue:1

    Topics: Amobarbital; Barbiturates; Chromatography, Gas; Dose-Response Relationship, Drug; Female; Humans; Hy

1973
Suppression of fetal breathing to prevent aspiration of meconium.
    Obstetrics and gynecology, 1970, Volume: 36, Issue:6

    Topics: Amniotic Fluid; Amobarbital; Animals; Asphyxia Neonatorum; Atropine; Female; Fetal Diseases; Fetus;

1970
[Dolo-Buscopan in gynecology].
    Medizinische Klinik, 1966, Sep-09, Volume: 61, Issue:36

    Topics: Abortion, Threatened; Aminopyrine; Amobarbital; Analgesics; Codeine; Female; Genital Diseases, Femal

1966